Single ventricle on cardiac MRI Poster No.: C-0414 Congress: ECR 2011 Type: Scientific Exhibit Authors: F. Secchi, V. G. Nardella, A. Giardino, G. Di Leo, F. 1 2 1 1 1 1 2 Sardanelli ; Milano/IT, Milan/IT Keywords: Congenital, MR, Vascular, Cardiovascular system, Cardiac DOI: 10.1594/ecr2011/C-0414 Any information contained in this pdf file is automatically generated from digital material submitted to EPOS by third parties in the form of scientific presentations. References to any names, marks, products, or services of third parties or hypertext links to thirdparty sites or information are provided solely as a convenience to you and do not in any way constitute or imply ECR's endorsement, sponsorship or recommendation of the third party, information, product or service. ECR is not responsible for the content of these pages and does not make any representations regarding the content or accuracy of material in this file. As per copyright regulations, any unauthorised use of the material or parts thereof as well as commercial reproduction or multiple distribution by any traditional or electronically based reproduction/publication method ist strictly prohibited. You agree to defend, indemnify, and hold ECR harmless from and against any and all claims, damages, costs, and expenses, including attorneys' fees, arising from or related to your use of these pages. Please note: Links to movies, ppt slideshows and any other multimedia files are not available in the pdf version of presentations. www.myesr.org Page 1 of 9
Purpose Our aim was to compare two approaches for single ventricle (SV) segmentation on cine MRI and to review our SV patients. Methods and Materials We studied 16 patients (13 males; aged 27±6 years) with diagnosis of single ventricle malformation. pure SV (n=6) tricuspid atresia (n=6) pulmonary atresia (n=2) double inlet (n=1) mitralic atresia (n=1) They underwent a 1.5T cardiac MRI with the following imaging protocol: ECG-triggered axial true-fisp or HASTE and cine true-fisp, ECG-triggered phase contrast on pulmonary and aortic plane, and MR angiography after 0.1 mmol/kg of gadobenate dimeglumine. We classified patients as having one or more of the following characteristics: right or left SV morphology dextrocardia D- or L-ventricle loop situs solitus or ambiguous D- or L-transposition of great vessels (TGA) A reader segmented the cine true-fisp images twice, firstly including only the systemic ventricle, secondly including both the systemic large ventricle and the small accessorial ventricle. Page 2 of 9
Ejection fraction (EF), normalized end-diastolic volume (EDVI) and end-systolic volume (ESVI) were calculated. Wilcoxon test was used. Images for this section: Fig. 1 Page 3 of 9
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Results Morphology analysis Six patients presented L-TGA, 4 dextrocardia, 3 D-ventricle loop, 3 right morphology of the single ventricle, 2 D-TGA, and 1 situs ambiguous. Volumes analysis 2 EDVI (ml/m ) was 74±41 segmenting only the systemic large ventricle, and 92±48 segmenting both ventricles; ESVI was 38±20 and 53±27, respectively. EF was 46±15% segmenting only the systemic large ventricle, and 41±13% segmenting both ventricles, with borderline significance (p=0.049). Images for this section: Fig. 1 Page 8 of 9
Conclusion These findings support the hypothesis that the small accessorial ventricle does not contribute to the pump function. MRI is an optimal technique to define the correct anatomy and morpholgy of patients with single ventricle. References C Lapierre, J De#ry, R Gue#rin, L Viremouneix, J Dubois, L Garel,. Segmental Approach to Imaging of Congenital Heart Disease. RadioGraphics 2010; 30:397-411. Personal Information Dr. Francesco Secchi Università degli Studi di Milano Facoltà di Medicina e Chirurgia Scuola di Specializzazione in Radiodiagnostica Via Festa del Perdono, 7-20122 Milano Tel +390252774468 Fax +390252774626 E-mail: francescosecchimd@gmail.com Page 9 of 9