M1. (a) (concentration high) in the hepatic portal vein is blood with glucose absorbed from the intestine 1

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M. (a) (concentration high) in the hepatic portal vein is blood with glucose absorbed from the intestine concentration is lower in the hepatic vein because insulin (has caused) glucose to be converted into glycogen or allows glucose into liver cells (i) (after 6 hours) most of the glucose has been absorbed from the intestine or from food into the blood (ii) because glucagon (made in the pancreas) causes if biological terms incorrectly spelt they must be phonetically accurate do not accept glucagon made / produced by the liver glycogen to be converted into glucose glucose released into blood allow the liver maintains the correct / constant level of glucose in the blood [7] Page 2

M2. (a) in rainforest: accept converse (water from) sweat does not evaporate (as much) max if not clear whether desert or rainforest any one from: (due to) less wind / higher moisture / humidity less cooling effect ignore references to temperature blood vessels supplying capillaries dilate / widen or vasodilation do not award mark if candidate refers only to blood vessels dilating or to capillaries dilating. accept arteries or arterioles for blood vessels supplying, capillaries but do not accept veins. ignore expand / get bigger / relax / open do not accept idea of blood vessels moving more blood (through skin / surface capillaries) leads to greater heat loss [4] Page 3

M3. (a) proteins are not filtered glucose is filtered and (re)absorbed allow glucose (completely) reabsorbed ions are filtered and some (re)absorbed allow some ions are reabsorbed urea is filtered [and some / none (re)absorbed] allow some / no urea is reabsorbed more / a lot of sweating occurred accept converse arguments for cold day more / a lot of water loss (by sweating) more / a lot of water reabsorption / more water absorption by the kidney lower volume of urine allow less urine / less water in urine [8] Page 4

M4. (a) 0.8 award both marks for correct answer irrespective of working if no answer or incorrect answer allow mark for 45 00 / 25000 2 heat / thermal allow heat from respiration (c) energy / mass / biomass lost / not passed on or energy / mass / biomass is used or not enough energy / mass / biomass left ignore reference to losses via eg respiration / excretion / movement / heat a sensible / appropriate use of figures including heron eg only 2 from frog / to heron ignore units (d) any three from: accept marking points if candidate uses other terms for microorganisms (microorganisms) decay / decompose / digest / breakdown / rot ignore eat (breakdown) releases minerals / nutrients / ions / salts / named ignore food (microorganisms) respiration ignore other organisms respiring (microorganisms / respiration) release of carbon dioxide 3 [8] Page 5

M5. (a) (i) hour 5 mins /.25 hours / 75 mins allow :5 ignore.5 hours (ii) increase in (core / body) temperature ignore numbers (due to an) increase in respiration or more muscle contraction releasing energy (as a waste product) allow produces heat do not allow making energy skin temperature decreases (because there is) sweating (which) evaporates and cools the skin ignore references to vasodilation or vasoconstriction (iii) (there is) dilation of vessels (supplying skin capillaries) allow vasodilation allow blood vessels widen ignore expand do not accept dilating capillaries or moving vessels (so) more blood flows (near skin) (surface) or blood is closer (to the skin) ignore ref to heat (c) pancreas detects (low) blood glucose produces glucagon Page 6

do not allow glucagon made in the liver (so) glycogen is converted to glucose allow adrenaline released which increases conversion of glycogen to glucose or reduced insulin production so less glucose into cells / less glucose converted to glycogen for mark [2] Page 7

M6.(a) if body temperature too high blood vessels supplying skin (capillaries) dilate / widen do not accept capillaries / veins dilate/constrict if body temperature is too low blood vessels supplying skin (capillaries) constrict / narrow do not accept idea of blood vessels moving (through skin) ignore expand accept arteries / arterioles for blood vessels if no reference to skin allow blood vessels dilate and blood vessels constrict for one mark so more / less blood flows through skin (capillaries) or nearer the surface of the skin must correctly relate to dilation or constriction so more / less heat is lost (from the skin by radiation) must correctly relate to dilation or constriction sweat released cannot evaporate because of high humidity / all the water vapour in the air so less heat lost / less cooling or it is evaporation of sweat that cools the body [7] Page 8

M7.(a) Pancreas allow phonetic spelling any three from: max 2 if any one process goes on in wrong organ (amino acids) broken down (amino acids) form urea (amino acids broken down / converted or urea formed) in liver (urea / broken down amino acids) removed / filtered by kidney do not allow amino acids filtered / removed by kidney (urine / urea / broken down amino acids) stored / held in bladder do not allow amino acids stored / held in bladder 3 [4] Page 9

M8. (a) (i) A (ii) (protein) molecule is large ignore letters cannot pass through filter (protein is) too big to get through the filter = 2 marks B is taken back into the blood or B is reabsorbed reabsorbed completely or reabsorbed after filtration (c) RBC is too big to pass through filter Haemoglobin is inside red blood cells or haemoglobin released when RBC bursts Haemoglobin is small enough to pass through filter or haemoglobin diameter [8] Page 0