/aedj EVALUATION OF THE CHANGES IN THE SOFT AND HARD TISSUE PROFILE AFTER ANTERIOR SEGMENTAL OSTEOTOMY OF MAXILLA AND MANDIBLE.

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10.5368/aedj.2017.9.3.1.4 EVALUATION OF THE CHANGE IN THE OFT AND HARD TIUE PROFILE AFTER ANTERIOR EGMENTAL OTEOTOMY OF MAXILLA AND MANDIBLE. 1 sudhakar Gudipalli 2 urekha.k 3 Anil Budumuru 4 Praveen Peramulla 5 Narendra kumar 6 Prasanna PVL. 1 Associate professor 2 Professor and Head 3 enior Lecturer 4 enior Lecturer 5 Post graduate 6 Post graduate 1-6 Department of oral and maxillofacial surgery, 1,2,5,6 Government Dental College and Hospital,Vijayawada, Andhra Pradesh. 4 Vishnu Dental college and Hospital, Bhimavaram, Andhra Pradesh. 5 Kamineni institute of Dental science,narketpally,nalgonda,telengana. ABTRACT: Aim of this study is to evaluate the changes in the soft and hard tissue profile after Anterior egmental Osteotomy of Maxilla and Mandible in Department of Oral and Maxillofacial urgery, Government Dental College and Hospital, Vijayawada. ubjects include 10 men and women who were diagnosed as bialveolar protrusion and underwent maxillary and mandibular anterior segmental osteotomy. tatistical analysis showed changes in both soft and hard tissues parameters. A reduction of the labial prominence with increase nasolabial angle was noted subsequent to anterior segmental osteotomies. Long term, prospective, methodology sound clinical trials with larger samples are required to provide sufficient information for predicting the soft and hard tissues changes response to anterior segmental osteotomies. KEYWORD: Anterior egmental Osteotomy, nasolabial angle, orthognathic surgery INTRODUCTION Orthognathic surgeries are utilized to alter or correct underlying hard tissues abnormalities. Anterior segmental osteotomy is indicated in excess vertical and or anterior posterior dimension of maxilla, bimaxilary protrusion, and anterior open bite and can be combined with other osteotomies to achieve optimal correction of dentofacial esthetics and occlusion 1-4. Aim of the study is to determine the relationship between the changes of soft and hard tissues after anterior segmental osteotomy of maxilla and mandible and evaluate unintentional facial changes using wolfolds and fields analysis has been used in our study. Materials and methods A study was conducted in Department of Oral and Maxillofacial urgery, Government Dental College and Hospital, Vijayawada conducted from November 2014 to eptember 2016 after due approval from hospital ethical committee. Ten patients aged 18-30 years who underwent anterior segmental osteotomy in were included in the study. Patients who underwent other orthognathic surgery and who were less than 18 years or more than 50years were excluded in the study. Preoperative OPG was taken to rule out any underlying abnormalities like bony lesions, supernumerary tooth etc. All the patients were assessed cephalometrically. Preoperative lateral cephalogram of the patient is taken and wolfolds and fields analysis was done on it to assess the skeletal and dental discrepancies which will aid in treatment plan. The postoperative follow up after the surgery is on 3 and 6 months. The soft tissue and hard tissue changes for 10 patients who underwent AMO alone or in combination with Lower sub apical osteotomy or Genioplasty were evaluated with the help of wolfolds and fields analysis and were calculated by subtraction of the corresponding preoperative values and calculation of percentage change for each patient. The data gathered was statistically analyzed The following landmarks were used in the study: 1. Upper incisal angulations 2. Lower incisal Angulation 3. N-A angle 4. 4.N-B angle 5. Lower anterior Dental height 6. N-Pg (mm) 7. Upper lip length 8. Thickness of Upper lip 9. Nasiolabial angulation 10. Labiomental angulation. 17a

Pre operative and post operative pictures of patient Case1 (Fig.1, Fig.2, Fig.3, and Fig.4) case 2(Fig.5, Fig.6, Fig.7, and Fig.8) Results Table1: All patients participating in this study were evaluated cephalometrically. (Table.1, Table.2, Graph1 and 2). On an average 40% of the patients undergone surgical procedures(anterior segmental osteotomy, genioplasty, lower subapical osteotomy)are within the age range of 18-25years and other 40% are of above 24 years of age. Table.1. Demographic details of the subjects ex No. of patients Percentage Female 7 70 Male 3 30 Table 2: The Age distribution of patients in current study Age No. of patients Percentage 18-20 4 40 21-23 2 20 >24 4 40 Based on the surgical procedures performed, patients were separated into two groups: Group I:One group includes only AMO and Group II: Another group includes bimaxillary procedures that include (Genioplasty or lower sub apical osteotomy along with AMO). Results on continuous measurements are presented on Mean +D (Min- Max) and results on categorical measurements are presented in Number (%). ignificance is assessed at 5 % level of significance. tudent t-test has been used to find the significance of study parameters on continuous scale within each group. tatistical analysis showed changes in both soft and hard tissue parameters. Changes were not uniform for all the parameters. Few parameters had significant changes where as others had suggestive significance or moderate significance The Pretreatment values of each the patient(n=10), comparison of the groups in correlation with the surgery performed, amount of hard tissue movement and percentage change for each variable.(table.3 and Table.4) The graph depicts that when AMO posterior and superior repositioning is done : (Graph :2). Graph that depicts that when AMO along with Genioplasty / lower anterior subapical osteotomy is done(graph 3) Discussion Anterior segmental osteotomy is indicated in the case where substantial movement of the anterior teeth is required, but where tooth repositioning by orthodontic 18a treatment alone is impossible because of objective factors such as the amount of tooth movement and periodontal circumstances, and subjective factors such as patient age, treatment time, and economic status. The specific relationships between the hard tissue structures and soft tissue profiles are variable. For some points, hard and soft tissue structure is closely related, but some are independent 1. Generally, the changes of the superior and inferior aspects of the profile, such as Nasion and pogonion, have shown to have more predictable patterns than those of the midface areas, such as the nose and lips. 2. The pair t test is most commonly used for the comparision of preopreative and post operative soft tissue and hard tissue changes. The parameters which have undergone significant changes were Upper incisal angulations, Upper lip length and Nasolabial angulation. Lines and teinhauser in their study reported soft tissue changes associated with the maxillary anterior segmental set back osteotomy which included an increase in the nasolabial angle because of posterior lip rotation around subnasale 3. Our study results are similar to the study of Lew et al who suggested lengthening of the upper lip, decrease in interlabial gap and retraction of the lower lip. 4 In our study soft tissue changes associated with AMO results in increase nasolabial angel due to which prognense of labial prominence has been reduced.the thicknesses of the upper lip in our study shows no significant change. These results are contrast to the study of Park et al in which thickness of upper lip is increased to 2.6% Park et al in their study evaluated hard and soft tissue changes after Anterior egmental Osteotomy on the Maxilla and Mandible. Mean values of Nasolabial angle preoperative was found to be (94.96± 9.67) and postoperative was found to be (109.03 ± 9.08) with a highly significant P value of < 0.0127. Mean value of nasolabial angulation (postoperative) in our study was found to be similar to the above study (110.80±13.4). The results of the upper incisal angualtion inner study is similar to the study of Kasai kazutaka et al in which upper incisal angulation decreased significantly post surgery from preoperative to post operative in a patient treated orthodontically. 1 The mean preoperative value for Labio mental angulation in cases of lower subapical osteotomy is 119.33 and the mean post operative value is 132.0. The P value is <0.05 depicting significance The mean preoperative value for Labio mental angulation in cases of Genioplasty is 145.5 and the mean post operative value is 128.5. The P value is <0.05 depicting significance. The mean ± D of preoperative values of Labiomental angulation in our study are 119.33±0.57 and the postoperative values are 132 ± 2.12 in patients undergoing bimaxillary procedure with upper anterior segmental osteotomy and lower subapical osteotomy. The

Table 3: Comparison of mean between pre and Post in different parameters(amo alone) by using paired t-test. Parameters Timing Mean D P- value Inference Upper Incisal Angulation Pre 35.80 9.20 Post 26.40 5.43 <0.05 N-A angle Pre 89.80 2.86 N Post 87.20 3.31 0.23 Upper lip length Pre 19.60 2.06 Post 23.80 3.12 <0.05 Thickness of upper lip Pre 15.20 2.23 N Post 17.20 2.71 0.39 Nasolabial angle Pre 82.20 13.06 Post 110.80 13.54 <0.05 Table 4: Comparison of mean between pre and Post in different parameters by Bimaxillary procedure using paired t-test. Parameter Timing Mean D P-value Inference Upper Incisal Angulation Pre 34.60 8.99 Post 23.60 2.19 <0.05 Lower Incisal Angulation Pre 38.40 8.08 <0.05 Post 26.60 4.98 N-B Angle Pre 86.00 3.46 0.20 N Post 83.00 3.96 N-A Angle Pre 90.40 3.78 0.41 N Post 86.00 3.74 Lower Anterior Dental Height Pre 38.60 2.41 0.29 N Post 41.00 3.32 N-Pg linear distance{mm} Pre 2.30 0.45 0.78 Post 2.70 0.84 Upper lip length{mm} Pre 15.60 2.30 <0.05 N Post 21.60 2.41 Thickness of upper lip{mm} Pre 13.60 1.52 0.31 N Post 16.20 2.49 Nasolabial Angulation Pre 85.20 11.99 <0.05 Post 102.00 10.20 LabiomentalAngulation Pre 119.33 0.57 <0.05 (lower subapical osteotomy) Post 132.00 2.12 LabiomentalAngulation (Genioplasty) Pre 145.50 3.46 <0.05 Post 128.50 3.54 19a

Graph1: depicting the percentage of the patients undergoing the type of and the average range of their ages Graph 3 : Graph corresponding to table 3 depicting the preoperative and post operative value for each variable in AMO group 20a

Case1. Fig. 1: Pre operative (frontal and lateral view) Fig. 2: Intraoperative photograph showing down fracture of the maxilla Fig. 3: Postoperatie (frontal and lateral view ve (Frontal & Lateral views) Fig. 4: Pre& Post Operative Radiographs 21a

Graph 3: This graph corresponding to table 4 depicting the pre operative and post operative value for each variable in bimaxillary group patients results in our study are similar to studies of Kasai Kazutaka et al in which the Labiomental angulation increased significantly post-surgery from preoperative (136.7±12.9) to postoperative (138.9±9.5) in patients treated orthodontically 1. The results obtained in both procedures regarding Labiomental angulation (AMO along with Lower ub-apical osteotomy or advancement Genioplasty) is contrary to the studies of Harshitha et al in which no significant post-operative changes of Labiomental angulation had occurred 5. Our study results are also dissimilar to the study of Park et al. in which no statistically significant change occurred in Labiomental angle 6. The parameters which underwent significant changes were upper incisal angulation, lower incisal angulation, nasolabial angulation and Labiomental angulation and upper lip length value has undergone a highly significant change in our study For the patients who underwent advancement Genioplasty a moderately significant increase in chin prominence was observed. This shows that there is significant change in the chin which is in agreement with the following studies. Krekmanov and Kahnberg 7 reported that the soft tissue changes following horizontal advancement Genioplasty depend on the magnitude and direction of the positional change of the genial segment and minimal soft tissue 22a stripping. The profile became straighter after advancement Genioplasty procedures. Anterior segmental osteotomy might be recommened as treatment modality of choice in patient with bimaxillary and or dentoalveolar protrusion. The technique is simple, post operative complications are minimal, relapse is limited and soft tissue changes in response to surgery are more predictable.it may take atleast six months for post surgical edema and hematoma to resolve and soft tissue to stabilize. CONCLUION On the basis of this study conducted in the Department of Oral and Maxillofacial urgery, Government Dental College and Hospital, Vijayawada, we have made an attempt to assess the soft and hard tissue profile changes after Anterior segmental osteotomy of maxilla and mandible surgical procedures. This study was conducted on 10 patients and following conclusions were drawn. In Anterior segmental osteotomy of maxilla alone by posterior and superior repositioning there is increase in the Nasolabial angle, Upper incisal angle, and upper lip length. Whereas N - A angle and thickness of upper lip doesn t show significant change.

Case-2. Fig. 5: Pre operative (frontal and lateral view) Fig. 6:Intraoperative showing AO of Maxilla and Anterior ub apical osteotomy of mandible. Fig. 7. Postoperatie (frontal and lateral view ve (Frontal & Lateral views) Fig. 8: Pre& Post Operative Radiographs 23a

For Anterior segmental osteotomy of maxilla along with anterior mandibular subapical osteotomy there is increase in Upper incisal angulation and Lower incisal angulation, Upper lip length, Nasolabial angle, Labio mental angulation. For Anterior segmental osteotomy of maxilla along with Advancement Genioplasty there is increase in Upper incisal angulation and Lower incisal angulation, Upper lip length, Nasolabial angle and decrease in Labio mental angulation was seen. In both the bimaxillary groups N-A angle, N-B angle, Lower anterior dental height, Thickness of upper lip, N- Pog distance didn t show significant change. The post operative changes in the soft tissue profile were understood better by the patients by comparing pre and postoperative cephalograms during the follow up. The limitations of the present study include relatively smaller sample size with short term follow up and the methodology used for measurement of some of the parameters is manual rather than software based and purely based on observer skills in tracing cephalograms. It is anticipated that, a larger sample size with long term follow up study, would enable a more detailed output with definitive conclusion. References: 1. Kasai K. oft tissue adaptability to hard tissues in facial profiles. American journal of orthodontics and dentofacial orthopedics. 1998 Jun 30;113(6):674-84.. 2. Proffit WR, Epker B. Treatment planning for dentofacial deformities. In: Bell WH,White RP, editors. urgical correction of dentofacial deformities. Philadelphia: WB aunders; 1980. p. 183 7. 3. Lines PA, teinhauser E. oft tissue changes in relationship to movement of hard tissue structures in orthognathic surgery: a preliminary report. Journal of Oral urgery 1974; 32:891 6. 4. Lew KKK, Loh F,Yeo JF. Profile changes following anterior subapical osteotomy in Chinese adults with bimaxillary protrusion. Int J Adult Orthodon Orthognath urg 1989; 4:189 96. 5. Harshitha KR, rinath N, unil Christopher H. Evaluation of soft and hard tissue changes after anterior segmental osteotomy. Journal of clinical and diagnostic research: JCDR. 2014 ep;8(9):zc07. 6. Park JU, Hwang Y. Evaluation of the soft and hard tissue changes after anterior segmental osteotomy on the maxilla and mandible. Journal of Oral and Maxillofacial urgery. 2008 Jan 31;66(1):98-103. 7. Krekmanov L, Kahnberg K. oft tissue response to genioplasty procedures. Br J Oral Maxillofac urg 1992; 30:87 91. 8. Johan P Reyneke. Essentials of Orthognathic urgery. Quintessence Publishsing Co. Inc, 2003. 24a 9. Burstone C J, James R B, Legan H, Murphy G A, Norton L A Cephalometrics for orthognathic surgery. J Oral urg 1978; 36: 269 77. 10. Peter ward booth. urgical planning in orthognathic surgery. Elsevier publications, second edition, volume 2, 2007. 11. Athanasious and Athanasiou. Orthodontic Cephalometry. Mosby Wolfe.95. 12. B.Rosenquist.Anterior segmental maxillary osteotomy. IJOM 1993; 22; 210 13. Edward Hui, soft tissue changes following maxillary osteotomies in cleft lip and palate and non cleft patients. 14. Pedersen GW. The versatility of mandibular subapical procedures. Oral urgery, Oral Medicine, Oral Pathology. 1973 Apr 30;35(4):448-61. 15. Pedersen GW, Blaho DM. Correction of mandibular dentoalveolar retrusion by anterior segmental advancement. Oral urgery, Oral Medicine, Oral Pathology. 1976 Mar 31;41(3):281-92. 16. Radney LJ, Jacobs JD. oft-tissue changes associated with surgical total maxillary intrusion. American journal of orthodontics.1981 Aug 1;80(2):191-212 17. Holland GR, Robinson PP. Reinnervation of teeth after segmental osteotomy. International journal of oral and maxillofacial surgery.1986aug31;15(4):437-43. 18. Martis C, Martis K, Papadogeorgakis N. A modified anterior maxillary osteotomy: 15 years experience. British Journal of Oral and Maxillofacial urgery. 1991 Jun 1;29(3):213-4. 19. Rosenquist B. Anterior segmental maxillary osteotomy: A 24-month follow-up. International journal of oral and maxillofacial surgery. 1993 Aug31;22(4):210-3. 20. Harshitha KR, rinath N, unil Christopher H. Evaluation of soft and hard tissue changes after anterior segmental osteotomy. Journal of clinical and diagnostic research: JCDR. 2014 ep;8(9):zc07 Corresponding Author Dr.urekha.K Professor and Head Department of oral and maxillofacial surgery Government Dental College and Hospital, Vijayawada- 520004 Phone no : 8008372713 E-mail:gsletterbox@gmail.com