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Scientific Program ici Wednesday, July 7, 2010 ici Imaging in Cardiovascular Interventions 07:00 18:00 Registration 07:00 08:00 Breakfast at the Congress Center 08:00 08:10 Welcome and Introduction N. Wunderlich, H. Sievert 08:10 09:30 Session 1 Strengths and Weaknesses of Imaging Modalities Chairpersons: N. Wilson, N. Weissman Ultrasound TEE N. Weissman TTE D. Hildick-Smith ICE T. Bartel 3-D J. Simpson MRI: Cardiac and Extracardiac CT: Cardiac and Extracardiac A. Bell O. Klass 09:30 10:30 Session 2 Atrial Septal Defects Chairpersons: S. Qureshi, N. Wunderlich Morphology of ASDs Morphological Suitability of ASD Closure Based on Imaging Follow-up by Imaging: Residual Shunt, Complications and Remodeling Post Closure How do Pulmonary Hypertension and LV Function Influence the Management of ASD Closure? Y. Ho M. Witsenburg A. Cabalka R. Ibrahim 10:30 11:00 Coffee Break and Industry Exhibition 11:00 12:00 Session 3 Patent Foramen Ovale Chairpersons: N. Wilson, M. Carminati Morphology of PFO PFOs - Why are Some More Dangerous Than Others? Live Demonstration of Right-to-left Shunting With Transcranial Doppler Diagnosis and Management of Residual Shunt A. Cook O. Ormerod E. Onorato, G.P. Anzola O. Franzen 12:00 13:00 Session 4 Left Atrial Appendage Chairpersons: S. Qureshi, N.Wunderlich Morphology of the LAA How to Evaluate the LAA by Echo I am Using CT I am Using MRI Y. Ho J. Newton J.-W. Park J. Lopez Minguez

Intraprocedural Imaging During LAA Closure N. Wunderlich 13:10 14:20 Lunch Sessions and Industry Exhibition A1 Live Practical Demonstration: How to do 3D Transthoracic Echo Chairperson: D. Schranz 2D/3D TTE J. Simpson D1 Diagnostic Approach (TEE) for ASDs and PFOs: Step by Step Chairperson: E. Onorato Recorded Case of ASD Evaluation Different Types of ASDs Morphologic and Functional PFO Evaluation PFO Closure With the FlatStent EF Specific Morphological Considerations P. Zartner S. Giusti J. Woehrle E. Onorato E1 MitraClip Procedure Step by Step Supported by an Unrestricted Educational Grant From Abbott Vascular-Structural Heart Chairperson: O. Franzen The use of 3D Echo in Patient Identification for the MitraClip Therapy The use of Live 3D TEE During the MitraClip Procedure The Cardiac Surgeon s Perspective R. Siegel O. Franzen F. Maisano Spektrum 1 Catheter Treatment of Mitral Regurgitation Chairpersons: A. Moritz, S. Kar Echocardiographic Anatomy of the Mitral Valve and Evaluation of Mitral A. Hagendorff Regurgitation Selection of Appropriate Techniques for Reduction of Mitral Regurgitation Who is Suitable for Ring Reduction Techniques? S. Sack Who is Suitable for Leaflet Repair? S. Kar Spektrum 2 Intracardiac Echocardiography Chairperson: J. Newton Introduction to Technique Standard Views T. Bartel Use in Atrial Septal Defects and PFOs A. Cabalka Use in Other Structural Diseases J. Newton Conclusio 1 Ventricular Septal Defects Chairperson: M. Carminati Morphology and Echo Appearance of Different Types of VSDs Intraprocedural Guidance in VSD closure Special Considerations in Post Infarction VSD Closure The Chinese Experience in Imaging During VSD Closure J. Vettukattil G.F. Butera D. Hildick-Smith X. Kong 14:30 15:00 Session 5 Imaging of Pulmonary Arteries and Aortic Arch Chairpersons: N. Wilson, A. Mahnken How to Identify Significant Pulmonary Artery Pathology How To Identify Significant Aortic Pathology A. Bell T. Kuhne 15:00 15:45 Session 6 Mitral Valvuloplasty and Mitral Valve Repair Chairpersons: S. Qureshi, S. Kar

Morphology and Pathology Assessment of Suitability for Mitral Balloon Valvuloplasty Suitability for Mitral Valve Repair The Benefits of Live 3D TEE for MitraClip Procedures Y. Ho C. Esteves S. Kar R. Siegel 15:45 16:30 Session 7 Pulmonary Valve Implantation Chairpersons: N. Wilson, M. Carminati Suitability and Predictors of a Good Result Echo M. Gewillig CT and MRI A. Bell Follow-up After Pulmonary Valve Implantation P. Bonhoeffer 16: 30 17:00 Tea Break and Industry Exhibition 17:00 18:00 Session 8 Aortic Valve Implantation Chairpersons: S. Qureshi, A. Hagendorff Percutaneous Balloon Pulmonary Valvuloplasty Using New Balloon Catheter in Children: Initial Clinical Experience S. Jiang Suitability and Predictors of a Good Result Echo D. Messika-Zeitoun CT and MRI A. Mahnken Intracardiac Echo to Guide Percutaneous Valve Implantation Echocardiographic Follow-up Closing Remarks and Thank you 18:00 20:00 Welcome Reception Wine and Cheese Special Lecture: Why German Wine? J. Kefer A. Hagendorff N. Wunderlich, H. Sievert P. Wurm, J. Klein

Scientific Program CSI Thursday, July 8, 2010 CSI Congenital and Structural Interventions 07:00 19:00 Registration 07:00 08:00 Breakfast at the Congress Center 08:00 08:05 Welcome and Introduction H. Sievert, N. Wunderlich 08:05 08:15 13 Years of Live Transmissions K. Renkhoff 08:15 10:30 Session 1 What is new? Devices and Techniques Chairperson: M. Carminati Moderator: S. Qureshi Live Cases from Riyadh and Frankfurt Evolving Concepts of Transcatheter Valve Therapy Pulmonary Outflow Tract Reducer Devices for Left Atrial Appendage Closure on the Horizon Techniques for Transapical Chordal Implantation Tricuspid Valve Implantation C. Ruiz P. Bonhoeffer N. Wunderlich F. Maisano H.R. Figulla, A. Lauten Live Cases from Riyadh and Frankfurt 10:30 12:20 Session 2 Atrial Septal Defects Chairperson: M. Tynan Moderator: S. Qureshi Live Cases from Riyadh and Frankfurt Pathology of ASDs in Children and Adults Interactive Case Presentation Do not Attempt to Close These ASD: Anatomical and Physiological Contraindications Can we Anticipate Complications? A. Cook S. Qureshi M. Schneider J. Lock Live Cases from Riyadh and Frankfurt 12:30 13:50 Lunch Sessions and Industry Exhibition A1 Mitral Valvuloplasty Chairperson: C. Ruiz Who are Good Candidates for Mitral Valvuloplasty and Where are the D. Messika-Zeitoun

Limits? How to do it and how to Avoid and Manage Complications A Case Based C. Esteves Interactive Discussion D1 Aortic and Pulmonary Valve Implantation With the Edwards SAPIEN XT Valve Supported by an Unrestricted Educational Grant From Edwards Chairpersons: M. Doss What is Important in Valve Design Evolution and Performance? What Clinical Expectations Should we Demand from TAVI in 2010? Patient Selection and TAVI Procedures Edwards SAPIEN Valve in Pulmonary Position M. Fusari P. MacCarthy D. Tchetche Z. Hijazi E1 Devices for Left Atrial Appendage Closure Chairperson: K. Walsh Sideris Patch Occlutech AGA Watchman Coherex pfm Medical Device Other new Devices E.B. Sideris Z. Hijazi K. Walsh Z. Turi M. Mullen A. Javois J. Wiebe Spektrum 1 Pulmonary Atresia With Intact Septum Chairperson: J. De Giovanni Prenatal Detection and Progression Techniques of Catheter Valvotomy Contraindications for Catheter Intervention Acute and Long-term Outcome G. Sharland J. De Giovanni M. Schneider F. Berger Spektrum 2 Clinical Data on PFO Closure Supported by an Unrestricted Educational Grant From AGA Medical Corporation Chairperson: M. Tynan Closure Rate of 3 Different PFO Devices The German Heart Center Berlin Experience The Milano Experience M. Turner P. Ewert M. Carminati Conclusio 1 VSD Closure Devices: Design and Device Specific Tips and Tricks Chairperson: J. Masura Amplatzer pfm Medical Coil Chinese Devices Sideris Patch G.F. Butera R. Kozlik-Feldmann X. Kong E.B. Sideris Conclusio 2 Innovators Workshop: How To Make Things Happen Chairperson: J. Cheatham, P. Bonhoeffer From the Idea to the Patent From Angel-Investment to Exit A. Khairkhahan F. Groenewegen

Prototype Development P. Bonhoeffer First in Man Trial and CE Mark Approval F. Baumgarten 14:00 16:00 Session 3 Patent Foramen Ovale Chairperson: M. Carminati Moderator: S. Qureshi Live Cases from São Paulo and Frankfurt Update on Randomized Trials How to Approach Residual Shunts Complications M. Reisman M. Turner G.F. Butera Live Cases from São Paulo and Frankfurt 16:00 18:00 Session 4 Left Atrial Appendage Chairperson: S. Kar Moderator: N. Wunderlich Live Cases from São Paulo and Frankfurt Step by Step With the Watchman Device P. Sick With the ACP K. Walsh Early Results ACP Update on Watchman N. Wilson Z. Turi Live Cases from São Paulo and Frankfurt 18:10 19:30 Evening Sessions and Industry Exhibition A1 How to Close Challenging ASDs: A Case Based Discussion Chairperson: J. De Giovanni Large ASDs Multiple Defects Deficient Rims J. Masura J. Cheatham N.L. Hieu D1 Catheter Based Mitral Valve Repair With the MitraClip Supported by an Unrestricted Educational Grant From Abbott Vascular- Structural Heart Chairperson: F. Maisano Preprocedural Patient Evaluation MitraClip Repair Step by Step How to Manage Difficult MitraClip Procedural Situations N. Wunderlich O. Franzen S. Kar E1 How to Close Fistulas and Shunts Chairperson: J. Lock Prenatal Detection and Progression Indications and Techniques for Coronary Fistula Closure Transcatheter Closure of Pulmonary AV Fistulas G. Sharland P. Zartner J. Lock

New Devices for Fistula Closure AVP IV R. Martin DCS Coils COOK M. Schneider Spektrum 1 Paravalvar Leaks Chairperson: A. Cabalka How To Evaluate Aortic Paravalvar Leak Closure Mitral Paravalvar Leak Closure Transapical Approach Multicenter Experience J. Newton A. Cabalka R. Ibrahim C. Ruiz J. De Giovanni Spektrum 2 Patent Ductus Closure Chairperson: N. Wilson Devices for PDA Closure Z. Amin The Problem of the Silent Duct M. Witsenburg The Problem of the Large Duct L. Benson Duct Closure in Premature Babies in the Incubator Under Echo Guidance N. Wilson Conclusio 1 Which Device for which PFO? Chairperson: E. Horlick PFO With Septal Aneurysm M. Chessa PFO With Long Tunnels: Premere PFO Closure Device J. Woehrle In-Tunnel Device E. Onorato Residual Shunt After PFO Closure: What to do? E. Horlick Conclusio 2 How to get and Manage Transapical Access Chairperson: Z. Hijazi Surgical Technique Percutaneous Technique Using Perclose Transapical Closure with the Nobles Medical Technology Just do it - and Have Coils and Plugs Ready M. Doss M. Gewillig A. Nobles Z. Hijazi 20:00 23:00 Faculty Dinner Friday, July 9, 2010 CSI Congenital and Structural Interventions 07:00 18:00 Registration 07:00 08:00 Poster Session and Breakfast at the Congress Center Chairpersons: J. Weil, G. Brzezinska-Rajszys, H. Ince, F. Freudenthal 08:00 10:30 Session 5 Ventricular Septal Defects Chairpersons: J. Lock, S. Qureshi Moderator: N. Wilson

The Pathologist View: Which VSDs can be Closed A. Cook Step by Step - Perimembranous X. Kong - Muscular Z. Amin Interactive Case Based Discussion S. Qureshi 10:30 12:20 Session 6 Diseases of the Aortic Arch Chairperson: J. De Giovanni Moderator: S. Qureshi Technical Considerations for Coarctation Treatment Interactive Case Based Discussion Considerations in Growing Patients G. Brzezinska-Rajszys S. Qureshi M. Schneider 12:30 13:50 Lunch Sessions and Industry Exhibitions A1 In-Tunnel PFO Closure With the Coherex FlatStent EF Supported by an Unrestricted Educational Grant From Abbott Vascular- Structural Heart Chairperson: E. Onorato Why an In-Tunnel Device? Tunnel Morphology and Patient Selection FlatStent EF Implantation: Procedural Steps and Keys to Success Clinical Trial Results B. Whisenant M. Noc M. Mullen E. Onorato D1 Left Atrial Appendage Closure With the Watchman Device Supported by an Unrestricted Educational Grant From Atritech Chairperson: H.R. Figulla LAA Closure with the Watchman PROTECT AF/ASAP Clinical Data LAA Anatomy and Imaging Watchman LAA Closure Procedural Technique P. Sick N. Wunderlich S. Kar E1 ASD Closure Devices Around the World Chairpersons: F. Freudenthal, N. Wilson AGA NMT Occlutech Solysafe Lifetech Sideris Patch pfm Medical Device Helex The Cardia Ultrasept Device Other Devices I. Daehnert L. Benson Z. Hijazi R. Hirsch X. Kong E.B. Sideris M. Granja M. Schneider F. Pinto N. Wilson

Spektrum 1 Aortic Valve Implantation With the CoreValve Chairperson: J.C. Laborde How to Screen the Patients for CoreValve? CoreValve Implantation Step by Step Tips and Tricks J. Kovac H. Ince J.C. Laborde Spektrum 2 Fetal Interventions Assessment of Anatomy and Potential for Intervention Chairperson: M. Tynan Aortic Valvuloplasty Pulmonary Valvuloplasty Cases When we Should Avoid Intervention Aortic Pulmonary J. Lock G. Tulzer J. Simpson G. Sharland Conclusio 1 How to Close PFOs A Case Based Teaching Session Chairperson: D. Hildick-Smith Are There PFOs Difficult to Cross? PFO and Aneurysm: Should we Just Close the Hole or Cover the Whole Aneurysm? Long Tunnel PFO: Tips and Tricks My Most Difficult PFO Cases D. Hildick-Smith O. Franzen A. Rodrigues R. Kozlik-Feldmann Conclusio 2 Coarctation Angioplasty and Stenting Chairperson: E. Bruckheimer Indications and Contraindications Angioplasty and Stent Techniques Dealing With Near Atresia How to deal with transverse arch hypoplasia E. Horlick E. Bruckheimer P. Ewert J. Cheatham 14:00 14:20 Special Lecture: Accidents: Investigation, Blame and Prevention N. Dann 14:20 16:00 Session 7 Aortic Valve Disease Chairperson: S. Qureshi Moderator: N. Wunderlich Patient Selection for Aortic Valve Implantation: The Untreated Population B. Iung Latest Results: CoreValve J.C. Laborde Edwards H. Baumgartner Aortic Valvuloplasty in Children and Young Adults: What Should the Patient Leave the Cath Lab With? J. Lock 16:00 18:00 Session 8 Diseases of the Pulmonary Valve and Arteries Chairperson: L. Benson

Moderator: N. Wilson The Spectrum of RVOT Conduits Long-term Follow-up of Pulmonary Valve Implantation Future Perspectives of Pulmonary Valve Implantation S. Westaby J. Nordmeyer M. Carminati 20:00 23:00 Social Dinner Saturday, July 10, 2010 CSI Congenital and Structural Interventions 07:00 16:00 Registration 07:00 08:00 Breakfast at the Congress Center 07:15 08:00 Challenging Cases Chairperson: N. Wilson 08:00 10:30 Session 9 Mitral Valve Regurgitation Chairperson: S. Kar Moderator: A. Cabalka Live Cases from Berlin and Frankfurt Pathology of Mitral Valve Disease Surgical Approaches to Mitral Valve Repair Overview of Clinically Available Ring Reduction Techniques State-of-the-art: Catheter-based Double Orifice Mitral Repair Y. Ho A. Moritz S. Sack S. Kar Live Cases from Berlin and Frankfurt 10:30 12:20 Session 10 Devices for Heart Failure Management Chairperson: S. Kar Moderator: S. Qureshi Live Cases from Berlin and Frankfurt Devices for Monitoring Heart Failure Treatment Devices for Managing Acute Heart Failure Update on the Parachute Stem Cell Therapy: Concepts and Clinical Results S. Kar R. Mueller E. Mazzaferri A. Zeiher Live Cases from Berlin and Frankfurt

12:30 13:50 Lunch Sessions and Industry Exhibition A1 D1 E1 Spektrum 1 Spektrum 2 Conclusio 1 Conclusio 2 How to do Transseptal Puncture Chairperson: C. Ruiz Techniques and Devices for Transseptal Puncture Echo Guidance Fluoroscopic Guidance Complications How to Avoid and Manage Vascular Access Complications when Using Big Sheaths Chairperson: Z. Turi Arterial and Venous Puncture Sites and Techniques Pre-closing With Perclose Large Bore Suture Based Closure With the Nobles Medical Device Complications of the Access Puncture Sites New PFO Devices Chairperson: E. Onorato Coherex FlatStent EF pfm Medical Device Early Experience with NobleStitch Suture Mediated PFO Closure Spider SeptRX Hybrid Procedures Chairperson: J. Cheatham Hybrid Approach to Hypoplastic Left Heart Intraoperative Pulmonary Arteries Stenting Hybrid VSD Closure Transcatheter Palliation of Duct Dependent Pulmonary Circulation Left Atrial Appendage Closure With the ACP Supported by an Unrestricted Educational Grant From AGA Medical Chairperson: K. Walsh Early European Experience Implanting the ACP: My First 20 Cases - What did I Learn? What Does it Take to Have a Successful ACP Program? Percutaneous Pulmonary Valve Implantation Moderator: M. Carminati Step by Step Technique for Melody Implantation Prestenting of the RVOT Complications: How to Avoid, how to Manage When They Occur New Valves for Aortic Implantation and New Devices for Mitral Valve Repair Chairperson: S. Kar HLT Jena Valve E. Horlick O. Ormerod TBD E. Horlick, O. Ormerod Z. Turi R. Mueller A. Nobles J. Thomson E. Onorato K. Renkhoff M. Mullen T. Lehr S. Kleshinski D. Schranz J. Cheatham Z. Amin L. Benson J.-W. Park M. Valdes-Chávarri K. Walsh N. Wilson M. Gewillig M. Carminati S. Kubo H.R. Figulla, J. Kempfert

Percutaneous Mitral Chordae Replacement Babic Technique U. Babic Viacor J. Kautzner Recor Medical MAS System J. Seguin Guided Delivery System S. Kar Other new Transcatheter Valve Techniques J. Kovac Percutaneous Mitral Valve Implantation - Animal Results G. Lutter 14:00 16:00 Session 11 Nightmare Cases Chairperson: N. Wilson Moderator: S. Qureshi Live Cases from Berlin and Frankfurt Case 1 Case 2 Case 3 Case 4 A. Rudzitis R. Hoedl H. Hara J.D. Ferreira Martins Live Cases from Berlin and Frankfurt Closing Remarks and Thank you N. Wilson, S. Qureshi