Board Review with The Chiefs. October 17, 2016 October 23, 2016

Similar documents
Testosterone Therapy in Men with Hypogonadism

ISSM QUICK REFERENCE GUIDE ON TESTOSTERONE DEFICIENCY FOR MEN

Hypogonadism 4/27/2018. Male Hypogonadism -- Definition. Epidemiology. Objectives HYPOGONADISM. Men with Hypogonadism. 95% untreated.

Prior Authorization Criteria Update: Androgens, Topical and Parenteral

The PSA, Prostate Cancer Screening, and other Prostate Treatment Secrets!

The PSA, Prostate Cancer Screening, and other Prostate Treatment Secrets! Mark Bieri, MD!

Prostate Health PHARMACIST VIEW

Overview. Urology Dine and Learn: Erectile Dysfunction & Benign Prostatic Hyperplasia. Iain McAuley September 15, 2014

Testosterone Treatment: Myths Vs Reality. Fadi Al-Khayer, M.D, F.A.C.E

Benign Prostatic Hyperplasia. Jay Lee, MD, FRCSC Clinical Associate Professor University of Calgary

(dutasteride/tamsulosin) For the treatment of Benign Prostatic Hyperplasia (BPH)

Evaluation and Treatment of Primary Androgen Deficiency Syndrome in Male Patients

Index. urologic.theclinics.com. Note: Page numbers of article titles are in boldface type.

The term prostatitis refers to an inflammatory condition of the prostate gland in men.

Benign Prostatic Hyperplasia (BPH):

TESTOSTERONE DEFINITION

BIOCHEMICAL TESTS FOR THE INVESTIGATION OF COMMON ENDOCRINE PROBLEMS IN THE MALE

MANAGING BENIGN PROSTATIC HYPERTROPHY IN PRIMARY CARE DR GEORGE G MATHEW CONSULTANT FAMILY PHYSICIAN FELLOW IN SEXUAL & REPRODUCTIVE HEALTH

Appendix D Answers to the KAP Survey

A USER S GUIDE WHAT EVERY MAN NEEDS TO KNOW

Managing Testosterone Deficiency: A Practical Guide. John Grantmyre MD Professor of Urology Dalhousie University

1/3/2008. Karen Burke Priscilla LeMone Elaine Mohn-Brown. Medical-Surgical Nursing Care, 2e Karen Burke, Priscilla LeMone, and Elaine Mohn-Brown

Cialis. Cialis (tadalafil) Description

6/14/2010. GnRH=Gonadotropin-Releasing Hormone.

Testosterone Oral Buccal Nasal. Android, Androxy, Methitest, Natesto, Striant, Testred. Description

Testosterone Oral Buccal Nasal. Android, Androxy, Methitest, Natesto, Striant, Testred. Description

Testosterone Oral Buccal Nasal. Android, Androxy, Methitest, Natesto, Striant, Testred. Description

All about the Prostate

Cialis. Cialis (tadalafil) Description

Index. D Digital rectal examination (DRE),

PROSTATIC ARTERY EMBOLISATION (PAE) FOR BENIGN PROSTATIC HYPERPLASIA. A Minimally Invasive Innovative Treatment

OVERVIEW OF PRESENTATION

Androderm patch, AndroGel packets and pump, Axiron solution, First- Testosterone, First-Testosterone MC, Fortesta gel, Testim gel, Vogelxo

GUIDELINES ON. Introduction. G.R. Dohle, S. Arver, C. Bettocchi, S. Kliesch, M. Punab, W. de Ronde

Testosterone Injection / Implant

The Royal Marsden. Prostate case study. Presented by Mr Alan Thompson Consultant Urological Surgeon

Basics of Male Libido: Dysfunction & Treatment. Ripu Hundal MD FACE First State Endocrinology Newark, DE

Elements for a Public Summary

Erectile dysfunction. By Anas Hindawi Supervised by Dr Khalid AL Sayyid

Management of LUTS. Simon Woodhams February 2012

UROLOGY TOPICS FOR SENIOR CLERKSHIP HEMATURIA

Late Onset Hypogonadism. Toh Charng Chee Hospital Selayang

Men s Health. Disclosures. Men s Health. Men s Health. Are men the weaker sex? 1/16/ th Annual Winter Refresher Course Family Medicine, MCW

AUCKLAND REGIONAL UROLOGY GUIDELINES AND REFERRAL RECOMMENDATIONS

Testosterone Injection and Implant

Testosterone Injection and Implant

Male Reproductive System

BLADDER HEALTH. Painful Bladder AUA FOUNDATION OFFICIAL FOUNDATION OF THE AMERICAN UROLOGICAL ASSOCIATION

Benign Prostatic Hyperplasia (BPH)

What You Need to Know

10/9/2015. Dana A. Brown, Pharm.D., BCPS Assistant Dean for Academics, Associate Professor of Pharmacy Practice Palm Beach Atlantic University

Late onset hypogonadism

Case studies: LUTS. Case 1 history. Case 1 - questions. Case 1 - outcome. Case 2 - history. Case 1 learning point 14/07/2015 DR JON REES

Men s Health Concerns: Widely Experienced, Widely Misunderstood Date: March 6, 2016

Testosterone Injection and Implant

Sexual dysfunction of chronic kidney disease. Razieh salehian.md psychiatrist

Urinary tract disorders

Prostatitis - A straight forward guide to

University Medical Center Brackenridge Specialty Clinics. Urology Clinic Worksheet

Index. urologic.theclinics.com. Note: Page numbers of article titles are in boldface type.

Benign Prostatic Hyperplasia. Shahideh Amini Pharm.D clinical pharmacy resident Tehran university of medical science Department of pharmacotherapy

Mini-Invasive Treatment in Urological Diseases Dott. Alberto Saita Responsabile Endourologia Istituto Clinico Humanitas - Rozzano

Clinical evaluation of infertility

Lower Urinary Tract Symptoms K Kuruvilla Zachariah Associate Specialist

Managing the Patient with Erectile Dysfunction: What Would You Do?

Prostate Cancer Case Study 2. Medical Student Case-Based Learning

Antibiotic Guidelines for URINARY TRACT/ UROLOGY infections

EAU GUIDELINES ON MALE HYPOGONADISM

What Is the Low T Syndrome? Is Testosterone Supplementation Safe?

Male Lower Urinary Tract Symptoms: Management in primary care and beyond. Daniel Cohen PhD FRCS(Urol) Consultant Urological Surgeon

Men s Health Topics. Learning Objectives. BPH Definition. The Prostate Gland. I have nothing to disclose. Mindi Miller, Pharm. D.

, David Stultz, MD. Erectile Dysfunction. David Stultz, MD September 10, 2001

Trans Urethral Resection of Prostate (TURP)

Alternative management of hypogonadism Tamoxifen. Emmanuele A. Jannini, MD Tor Vergata University of Rome ITALY

ANDROGEN DEFICIENCY Update on Evaluation and Management

Dr Prashant Jain. Sr. Consultant, Pediatric surgery BLK Superspeciality Hospital

The Centre for Men s Health

Sexual Health in Older Adults

Prostate Disease. Chad Baxter, MD

DEFINITION HX & PH/EX

Diagnosis and Mangement of Nocturia in Adults

Saving. Kidneys. Benign Prostate Disease

Low Testosterone Consultation Information

What to do about infertility?

TOPICS COVERED. Male Sexuality. Female Sexuality. Ø Age-Associated Changes Ø Physiology, Evaluation and Treatment of Erectile Dysfunction

Some prostatic diseases

Increasing Awareness, Diagnosis, and Treatment of BPH, LUTS, and EP

66 M with erectile dysfunction and abnormal labs RAJESH JAIN ENDORAMA 10/29/2015

Sexual Health and Dysfunction in the Elderly. Nadya S. Dávila Lourido, MD September 28, 2018

MEDICAL THERAPY. Endocrine Approaches. Página 1 de 5.

The Enlarged Prostate Symptoms, Diagnosis and Treatment

Late onset Hypogonadism. Dr KhooSay Chuan Department of Urology Penang General Hospital

Male History, Clinical Examination and Testing

Canadian Undergraduate Urology Curriculum (CanUUC): Prostate Diseases

Androgen deficiency. Dr Rakesh Iyer Staff Specialist in Endocrinology Calvary hospital

Male Hypogonadism. Types and causes of hypogonadism. What is male hypogonadism? Symptoms. Testosterone production. Patient Information.

Testosterone and PDE5 inhibitors in the aging male

Learning Objectives. The Impact of Testosterone. Diagnosis of Androgen Deficiency and Late Onset Hypogonadism (LOH) Prevalence of Androgen Deficiency

EAU GUIDELINES POCKET EDITION 3

Transcription:

Board Review with The Chiefs October 17, 2016 October 23, 2016

Overview Registration Exam Details Test Day Details Study Resources Study Strategies Women s Health Men s Health

What to Expect: Exam Registration http://www.abim.org/ Registration Period: December 1, 2016 to April 15, 2017 Process Register on website Token/ID comes in snail mail Sign up for dates (6 exam dates in August ) Cost $1,365 :( Can re-schedule/cancel on website

What to Expect: The Test 240 questions total (4 sections, 60 questions) 2 hours per section (2 minutes/question) + 100 minutes break time + Tutorial/Pledge of Honesty (40 minutes) All multiple choice questions Clinical Calculator Audio and Visual

What to Expect: Exam Day Starts at 8 A.M.; end time is up to you (around 2:30 to 5:00 p.m) Sign-in Process 2 forms of non-expired I.D Breaks Lockers

After the test Immediately After: Celebrate/Cry Then, try to forget about it Exam results can take up to 3 months, but will usually come out in October NOT CURVED Passing ~ 67% - 70%

Study Resources MKSAP 16/17 MKSAP Board Basics MKSAP Question Bank MKSAP Extra Questions MKSAP Audio UWorld Question Bank MedStudy Review Books (ex: First Aid) Dasgupta s Board Review

Study Strategies When is optimal time to start studying? Is there anything that surprised you about the test? How did you study for this test? Any tips for exam day? Is there anything you wish you did differently?

Men s Health

Topics Androgen Deficiency Erectile Dysfunction BPH Acute Scrotal Pain Acute Prostatitis

Question 1 A 35-year-old man is evaluated for a 2-month history of low libido. The patient had a normal puberty. Family history is unremarkable. He drinks two beers per week and takes no medication. On physical examination, vital signs are normal; BMI is 23. Visual field examination findings are normal, as is testicular size. No gynecomastia is noted. Studies: Follicle-stimulating hormone: 6 mu/ml (6 units/l) Luteinizing hormone: 5 mu/ml (5 units/l) Thyroid-stimulating hormone: 2.5 µu/ml (2.5 mu/l) Total testosterone (4 PM): 200 ng/dl (7 nmol/l)

Which of the following is the most appropriate next diagnostic test? A.Measurement of serum ferritin and iron saturation levels B. Morning serum free testosterone measurement C.Morning serum total testosterone measurement D.Testicular ultrasonography

Androgen Deficiency Symptoms/Signs: Fatigue, decreased strength, poor libido, ED, gynecomastia Initial Test: 8:00 AM total testosterone levels If >350 ng/dl, the hypogonadism is excluded If <200 ng/dl, then obtain second confirmatory morning level (needs 2 measurements) If in between these values, then obtain serum free testosterone Sex Hormone Binding Globulin Low in obesity, Type 2 DM, hypothyroidism, acromegaly High in hyperthyroidism, HIV, hepatitis, patients taking anticonvulsants If low, check FSH/LH. If FSH/LH high = Primary Testicular Failure Ex: Klinefelter, Atrophy 2/2 mumps, AI destruction, hemachromatosis, Previous XRT or chemo If low or normal FSH/LH = Secondary hypogonadism Hyperprolactinemia, hypothalamic/pituitary disorders (ex: Sarcoid, hemochromatosis), Use of opiates/anabolic steroids, glucocorticoids Side effects of androgen replacement therapy: Worsening sleep apnea, increased hematocrit, BPH, dyslipidemia

Androgen Deficiency Side effects of androgen replacement therapy: Worsening sleep apnea, increased hematocrit, BPH, dyslipidemia Therapy contraindicated if patients with prostate nodules, breast or prostate cancer, PSA >4 ng/ml or 3 ng/ml and at risk for prostate cancer, hematocrit >50%, severe lower urinary tract symptoms. Do NOT screen for androgen deficiency in asymptomatic men, regardless of age

Question 2 A 72-year-old man comes to your office for a routine health exam. He mentions that he cannot maintain an erection, and is seeking help. He denies decreased libido or loss of morning erections. His PMH is significant for diabetes mellitus, peripheral vascular disease, and CAD with stable angina. He is a former smoker, but quit 25 years ago. He drinks 2-3 alcoholic drinks per night approximately 5 nights/week. His medication list includes aspirin, atenolol, isosorbide dinitrate, and glipizide. Patient s vitals are 98.7F, 138/78, HR 61. BMI is 25. Physical exam, including genital exam, is normal. You counsel him on lifestyle modifications. Three months later he returns, with no improvements after he stopped his alcohol consumption. 8:00 AM Testosterone levels are 394 ng/dl, HgA1C is 6.7.

What is the next step? A.Prescribe testosterone gel B. Prescribe sildenafil C.Offer intraurethral alprostadil D.Obtain LH and FSH levels E. Continue lifestyle modifications

Erectile Dysfunction Many causes Vascular Neurogenic Endocrine Trauma/XRT/surgery to perineal/pelvic region Antihypertensive /antidepressant/anticonvulsant/antiadrogen/nsaid use EtOH/Tobacco/cocaine/opiate/marijuana High-Yield Points: 1st line therapy: lifestyle modifications (smoking/etoh cessation, exercise, etc.) PDE inhibitors (sildenafil, vardenafil or tadalafil) Contraindicated in men who receive nitrate therapy and history of nonarteritic anterior ischemic neuropathy (NAIN) Intraurethral/intracavernous alprostadil Intracavernous alprostadil contraindicated in severe coagulopathy/thrombocytopenia

Benign Prostate Hyperplasia Symptoms: nocturia, urinary frequency, urgency, incomplete bladder emptying, urinary retention, decreased urinary stream Perform DRE, obtain baseline AUA symptom index score UA to rule out underlying infection PSA testing is not required for diagnosis, does not need to be followed for therapy Lifestyle modifications: reduced fluid intake, timed voiding, limiting caffeine and EtOH consumption, discontinuing exacerbating medications Medications: Peripheral alpha-blockers (ex: tamsulosin) and 5-alpha-reductase inhibitors (ex: finasteride) Surgical interventions: TURP vs open prostatectomy

Acute Scrotal Pain Testicular Torsion EMERGENCY/RAPID SURGICAL DECOMPRESSION More common in men younger than 30 y.o Acute onset pain, nausea/vomiting Exam: absent cremasteric reflex, elevated/high-riding testis Doppler US shows diminished flow to affected testicle Epididymitis Pain less acute than torsion usually; may be accompanied by lower urinary tract symptoms Younger than 35 yo: ceftraixone/doxycycline. Older men and men who practice anal intercourse: ceftriaxone + Fluoroquinolone Noninfectious epididymitis: caused by reflux of urine into epididymis, leading to inflammation Treatment: scrotal support, ice, NSAIDs

Question 3 A 28-year-old man is evaluated for a 6-month history of pelvic pain, urinary frequency, and painful ejaculation. He has been treated with antibiotics for urinary tract infections three times in the past 6 months, each time with temporary relief of symptoms but recurrence shortly after completion of antibiotics. On physical examination, vital signs are normal. There is minimal suprapubic tenderness with palpation. The prostate is of normal size with minimal tenderness and no nodules. Urinalysis shows multiple leukocytes, bacteria, and no erythrocytes.

Which of the following is the most appropriate treatment of this patient? A.1-week course of trimethoprim-sulfamethoxazole B. 1-month course of ciprofloxacin C.Cognitive Behavioral Therapy D.Finasteride

Prostatitis Symptoms: pain in perineum, testes, penis, or suprapubic area; dysuria, urinary frequency, incomplete bladder emptying Initial studies; UA w/micro, urine culture (only needs imaging if you suspect abscess) Category I: Acute bacterial prostatitis 4-6 weeks of bactrim/fluoroquinolone If requires hospitalization: IV fluoroquinolone +/- gent (also obtain blood cultures) Category II: Chronic bacterial prostatitis 4-6 weeks of fluoroquinolone Category III: Chronic abacterial prostatitis/chronic Pelvic Pain Syndrome (CPPS) Trial of antibiotic, but mostly supportive care (ex: NSAIDs, alpha blockers) Category IV: No symptoms (detected by biopsy or presence of WBCs in semen samples)