Plan of the course. Integrated Clinical Module: Part 1. Academic year 2017/2018. izv. prof. dr. sc. Davorka Lukas

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UNIVERSITY OF ZAGREB SCHOOL OF MEDICINE Plan of the course Integrated Clinical Module: Part 1 Academic year 2017/2018

I. COURSE AIMS 1. COURSE AIMS: To introduce students to diseases that are prevalent in tropical and developing countries, to teach them aboat the epidemiology, causative organisms, clinical features, diagnosis, treatment and prevention of these diseases. The importance of pre-travel advice of travelers to endemic regions will be emphasized, as well as the importance of implementation of diagnostic and treatment algorithms, in a case of the occurrence of certain symptoms upon their return. To explore issues of migration medicine, indicate the importance of evaluating the health status of immigrants During exercise, special attention will be paid to proper examination of patients and taking appropriate epidemiological history Through seminars and practical work to teach students the methods of bacteriological, virological, parasitological and radiological diagnosis of tropical and travel diseases Several eminent speakers from abroad will participate in the lectures: Professor Nicholas White, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand and Centre for Tropical Medicine, Oxford University, UK II. COURSE STRUCTURE Course hours: : 20 : 28 Special clinical practicals: 12 Total hours: 60 (L): 20 s (S): 20 Practicals (P): 20 Total: 60 III. PLAN OF THE COURSE AND COURSE SCHEDULE BLOCKS OF THE COURSE Number of blocks: 1 Block number Start End 1. 6.11.2017 17.11.2017 BLOCKS OF THE COURSE

Number of blocks: 1 Block number Start End 1. 6.11.2017 17.11.2017 BLOCKS OF THE COURSE SHEME Block 1 Date Time Group Course hours type Theme Monday 6.11.2017. Tuesday 7.11.2017. Wednesday 8.11.2017. 09:00-10:30; 09:00-10:30; 09:00-10:30; Special clinical practicals A traveller returnig from tropical country with: diarrhoea HIV infection in the tropics and developing countries Melioidosis C ontrolling highly contagious infection in health-care settings C utaneous and mucocutaneous leishmaniasis Toxoplasmosis Clinical cases presentation Intestinal parasitosis Gastrointestinal infections: Viral hepatitis Teaching staff dr. sc. Neven Papić prof. dr. sc. Josip Begovac Šime Zekan, dr. med. dr. sc. Neven Papić Šime Zekan, dr. med. doc. dr. sc. Mirjana Balen Topić Jelena Lozić Davorka Dušek, dr. med.

Date Time Group Course hours type Theme Thursday 9.11.2017. 16:45-18:15; Friday 10.11.2017. 09:00-10:30; Monday 13.11.2017. 09:00-10:30; Tuesday 14.11.2017. 09:00-10:30; Special clinical practicals Special clinical practicals C linical case presetations C linical case presetations Radiology in Tropical medicine part I Tetanus. Intensive care medicine Haemorrhagic fevers dr. sc. Neven Papić Davorka Dušek, dr. med. dr. sc. Klaudija Višković doc. dr. sc. Marija Santini prof. dr. sc. Alemka Markotić Filariosis dr. sc. Neven Papić Travel medicine Visceral leishmaniasis Malaria Meningoccocal disease Typhoid, Echinococcois Teaching staff Goran Tešović doc. dr. sc. Mirjana Balen Topić

Date Time Group Course hours type Theme Wednesday 15.11.2017. 09:00-10:30; Thursday 16.11.2017. 09:00-10:30; Radiology in Tropical medicine part II African trypanosomiasis Tick typhus, Scrub typhus South American trypanosomiasis - C hagas disease Intensive care medicine, Rabies Teaching staff dr. sc. Klaudija Višković doc. dr. sc. Marko Kutleša Malaria 2 h (L): epidemiology, disease causative agent, transmission, clinical features, diagnosis and treatment 2 h (S): case presentaion of uncomplicated and complicated malaria and different treatment strategies. Malaria prevention. 2 h (P): thin blood film examination, study of parasite morphology and species identification; Visceral leishmaniasis (VL), cutaneous and mucosal leishmaniasis 2 h (L) epidemiology, disease causative agent, transmission, clinical features, diagnosis and treatment 2 h (S): case presentaion of differnet clinical features, diagnosis and treatment 2 h (P): stained bone marrow aspirate examination and detection of leishmania amastigotes South American trypanosomiasis - Chagas disease 2 h (S): case presentaion of differnet clinical features, diagnosis and treatment African trypanosomiasis

Dengue. Yellow fever 2 h (S): case presentaion of differnet clinical features, diagnosis and treatment Viral haemorrhagic fevers Schistosomiasis. Filariasis Leprosy. Tuberculosis 2 h (S) epidemiology, disease causative agent, transmission, clinical features, diagnosis, treatment and prevention Rabies. Tetanus 2 h (S) epidemiology, disease causative agent, transmission, clinical features, diagnosis, treatment and prevention Venomous bites and stings 2 h (S) epidemiology, clinical features, diagnosis, treatment and prevention Gastrointestinal infections: Cholera. Bacillary dysentery. Protozoal infections (Amoebiasis, Giardiasis). Intestinal cestode infections and cysticercosis. Soil-transmitted helminths. Hydatid disease 2 h (S): case presentaion of differnet clinical features, diagnosis and treatment 2 h (P): parasitology laboratory, diagnostic methods HIV infection in the tropics and developing countries

2 h (L) epidemiology, disease causative agent, transmission, clinical features, diagnosis and treatment 2 h (S): case presentaion of various clinical features of opportunistic diseases, diagnosis and treatment 2 h (S): radiologic methods in diagnosis tropical diseases Cutaneous tropical diseases. Tropical ulcer. Buruli ulcer. Cutaneous larva migrans. Myiasis. Drancunculiasis. 2 h (S) epidemiology, disease causative agent, transmission, clinical features, diagnosis and treatment A traveller returnig from tropical country with: 1. fever 2h P 2. rash 2h P 3. diarrhoea 2h P Migration medicine. Refugee health 2h (P) Travel medicine. Pre-travel advice for immunocompetent and special needs traveller, children, and pregnant women travelling to endemic countries, on the prevention, self-treatment. Travel vaccines 2h(L), 4h(P) will take place in the University Hospital for Infectious diseases (The Big Lecture Room) Mirogojska 8, 10 000 Zagreb LEARNING OUTCOMES At the end of the course students should be able to: Recognize most common diseases and syndromes in tropical and developing countries Analyze clinical, laboratory findings and treatment options Recognize the most prevalent health risks for travelers to tropical and developing countries and give advise on travelers diseases prevention Use available literature on tropical and travel medicine IV. EXAMINATIONS There is one Final Exam In order to approach the final exam, students have to have certificate that they have completed this course. The final exam will consist of 40 multiple-choice questions.

6. COURSE GRADES Final exam : 5 = excellent (A) 4 = very good (B) 3 = good (C) 2 = satisfactory (D) Fail (F) V./I. LIST OF LECTURERS AND TEACHING STAFF 1. prof. dr. sc. Josip Begovac 2. prof. dr. sc. Mihael Skerlev 3. prof. dr. sc. Adriana Vince 4. doc. dr. sc. Mirjana Balen Topić 5. doc. dr. sc. Marija Santini 6. Šime Zekan, dr. med. 7. doc. dr. sc. Marko Kutleša 8. Goran Tešović 9. Duška Tješić-Drinković 10. Davorka Dušek, dr. med. V./II EXTERNAL ASSOCIATES: 1. prof. dr. sc. Alemka Markotić 2. dr. sc. Klaudija Višković 3. doc. dr. sc. Suzana Bukovski 4. dr. sc. Neven Papić 5. dr. sc. Oktavija Đaković Rode 6. Jelena Lozić 7. Vanja Romih Pintar V./III UNTENURED LECTURERS: 1.

2. prof. dr. sc. Arjana Tambić Andrašević VI. LITERATURE Obligatory 01. Geoff Gill, Nick Beeching. Tropical Medicine. Lecture Notes: 6th ed. 2009. Published by Blackwell Publishing Additional Gordon C Cook, Alimuddin I Zumla. Manson's Tropical Diseases, 22nd Edition. Published by Saunders of Elsevier Ltd., London, UK, 2009. Handouts for seminars and practical work Additional readings (suggested by lecturer)