Living with Heart Failure. Sitaramesh Emani, MD Advanced Heart Failure & Cardiac Transplantation May 13, 2015

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Living with Heart Failure Sitaramesh Emani, MD Advanced Heart Failure & Cardiac Transplantation May 13, 2015

Definition of Heart Failure 1. Inability of the heart to keep up with demand 2. Failure of the heart to pump with normal efficiency

Common (but maybe inaccurate) synonyms Enlarged heart Weakened heart Cardiomyopathy But not the heart stopped working

What Are The Symptoms of Heart Failure? Think FACES... Fatigue Constant lack of energy Activities limited Difficulty with everyday activities Chest congestion Dry cough or producing white or pink bloodtinged phlegm Edema or ankle swelling Swelling of the feet, ankles, legs, abdomen, or unexplained weight gain Shortness of breath Breathlessness during activity, at rest, or while sleeping Additional symptoms: Lack of appetite, nausea, increased heart rate, irregular heart rhythm

Heart Failure is Very Common Heart failure affects nearly 5 million Americans 50% men and 50% women An estimated ½ million new cases are diagnosed each year Expected to rise to 750,000 new cases by 2040 Related to aging population, better treatment of heart disease and risk factors, awareness Over one million heart failure hospitalizations annually Rising over past few decades Accounts for over 20% admissions in people 65 and over

What Causes Heart Failure? Heart failure results after injury to the heart Heart attack High blood pressure Damage to heart valves Diabetes High cholesterol Heart muscle disease: damage from drugs, alcohol, or infections Congenital heart disease

Types of Heart Failure: Difference Between Systolic and Diastolic Heart Failure Aorta LA LV Dilated Thickened or stiff heart walls Normal Normal ejection (squeeze) =Systolic function Normal relaxation (filling) =Diastolic function Systolic Heart Failure Weakened pump Relaxation ± abnormal Blood backs up and overloads the heart Diastolic Heart Failure Normal ejection Abnormal relaxation: Stiff or scarred Won t allow enough blood to fill the heart before it squeezes Pg 238, Lilly 3rd edition

Simplified View of Systolic Heart Failure Normal Heart Development of Heart Failure

How Severe is A Patient s Heart Failure? We measure the ejection fraction by echo The fraction of blood that the heart pumps with every beat We assess the patient s symptoms No or mild symptoms We assess the patient s functional status

Heart Failure Treatment Guidelines

Heart Failure Mechanisms (simplified) Remodeling (β stimulation) CO = SV x HR Sympathetic Tone Apoptosis Afterload HR O 2 Demand SV CO Symptoms Afterload Renal Perfusion Na + + H 2 O Retention Remodeling (AT 2 pathways) RAAS 11

Treating Chronic HF (Simplified) β-blockers Sympathetic Tone Digoxin(?) Ivabradine HR O 2 Demand SV CO Diuretics Afterload Renal Perfusion Na + + H 2 O Retention Nitrates* Hydralazine* ACEi/ARBs Aldo-antagonism?LCZ696 RAAS 12

Why Do We Use These Treatments? Heart failure limits a patient's ability to perform the routine activities of daily living

Diuretics, ACE Inhibitors Reduce the number of sacks on the wagon (or load on the heart)

ß-Blockers Limit the speed, thus saving energy

Spironolactone, Cardiac Resynchronization Therapy Increase the heart s efficiency

How Do We Treat Heart Failure? Lifestyle Changes Quit smoking Monitor diet: low-fat, low sodium Exercise regularly Lose weight Avoid alcohol Limit caffeine intake

Limiting Sodium or Salt Will Improve Your Heart Failure Symptoms Sodium is a component of salt Naturally occurring in many foods Added during processing In most foods eaten away from home Sodium attracts fluid Fluid build-up in body Your body needs only a small amount of sodium to keep a normal fluid balance. Extra work on heart & kidneys to get rid of fluid Too much sodium causes your body to hold onto fluid and cause symptoms of weight gain, shortness of breath, and fatigue. Higher BP often results Heart failure symptoms, heart attack, stroke The more sodium (salt) you take in, the more fluid your body holds on to

Patients Should Follow a 2000 mg Sodium Diet In addition to heart failure patients, the American Heart Association recommends 1) All adults older than 51 2) All African Americans 3) Anyone with high blood pressure limit their daily intake to 1500 mg Plan your meals for 2000 mg intake MEAL Breakfast Lunch Dinner Snack mg Sodium 600mg 600mg 600mg 200mg Use alternative seasonings! Basil Parsley Chives Paprika Dill weed Pepper Garlic Sage Tarragon Mrs. Dash Thyme Lemon, lime juice

How It Shakes Out ¼ tsp salt = 600 mg sodium ½ tsp salt = 1200 mg sodium 1 tsp salt = 2300 mg sodium More than daily recommendation Even a small amount of salt counts! ½ tsp salt = 1 serving = 3 slices of ham =2 packets of = 3 pickles = 14 green pretzels soy sauce olives

Some common high sodium foods Frozen meals Pickles Canned foods Bacon Breads, baked goods Anchovies Lunch & smoked meats Soy sauce Cheese Seasoning mixes Condiments (salad dressing) Gravy Olives Salted crackers Pretzels FAST FOOD Rule of thumb: the more processed the food, the more sodium it contains

Learn how to read sodium labels on all food 1. Look for Sodium Listed as milligrams or mg 2. Next, look at serving size If you eat 2 servings of a food you need to double what you see on the label 3. Reduced-sodium products still contain sodium Always read the label

Sodium Guidelines < 140 mg = low sodium Enjoy these foods! 140-400 mg = medium sodium Use food in moderation > 400 mg = high sodium Use this food sparingly Low sodium Very low sodium Sodium-free 140 mg or less sodium per serving 35 mg or less sodium per serving Less than 5 mg sodium per serving 1. Use salt substitute or other spices when cooking (watch for high potassium in some substitutes) 2. Don t add salt at the table

Fluid intake & Daily Weights Limiting fluid intake: important in managing heart failure REMEMBER: Anything liquid at room temperature is considered a fluid Daily weights: every morning at the same time using the same scale Keep track of daily weights Typically, weight gain of 3 or more pounds in 24 hours OR 5 or more pounds in 48 hours can be a sign of fluid retention REMEMBER: You might not see swelling until you are 8-15# up

Exercise: Get Off the Couch!

Exercise Will Improve Your Quality of Life Pick a simple aerobic activity that you enjoy Start slowly and increase gradually Need to move large muscle groups Walking is a great first choice Resume activities you stopped (gardening, bowling, fishing) Work your way up to 30 minutes most days Doesn t have to be 30 minutes in a row Warm up and cool down Check with your physician first if You are really out of shape, uncertain about your abilities, or have shortness of breath with very mild activity

What if the Heart is Still Weak After Medications? Risk of death from cardiac arrest Defibrillators can protect the heart from these abnormal rhythms Based on the ejection fraction

Some Patients Need Pacemakers Pacemakers tell the heart when to beat Some versions resynchronize the chambers Based on EKG

Other Conditions Associated with HF Sleep Apnea is very common in HF patients Between 60-75% of HF patients have some form Sleep Apnea is inefficient breathing patterns at night Patients may sleep fine But the inefficiency can cause increased adrenaline

Symptoms of Sleep Apnea Fatigue Excessive daytime sleepiness Frequent naps Falling asleep while doing things (TV, driving) Feeling tired when you wake up

Benefits of Treating Sleep Apnea Increased energy Lower BPs Lower chance of irregular heart rhythms Increase in ejection fraction

What can you do? At home: Take your medicines Limit sodium and fluid intake Exercise Kick bad habits (smoking) Monitor weights and symptoms Have a support system

Friends and Family Emotional support helps a patient have a more positive outlook on life Allow the patient to make decisions regarding health care and lifestyle behaviors Positive reinforcement Discuss fears about heart failure Discuss advanced care planning Don t forget to take care of yourself: eat healthy, exercise, sleep

When to call your doctor A change in shortness of breath, fatigue, or swelling Requiring more pillows than usual to sleep comfortably at night or needing to sleep in a recliner Chest pain Near fainting or fainting Weight gain of more than 2 lbs in 24 hours or 5 lbs in 48 hours

What can we do? With your health care providers: Come to your visits Discuss problems with medications/side-effects Discuss changes in activity, energy, or mood Discuss signs of fluid retention

Into the future New therapies being developed all the time Better understanding of individual disease processes Continue to improve both survival and quality of life

Thank You