Geographic distribution ZIKV

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Shelley M. Wood, RN, BSN, CEN March 16, 2016 Geographic distribution ZIKV 1947 2007 http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2819875/ 1

Current Active Zika transmission WHO declared global health threat of international concern Feb http://www.cdc.gov/zika/geo/index.html ZIKV in the U.S. 2016 JAN Became nationally notifiable condition JAN Imported transmission to the U.S. FEB Sexual transmission in TX MAR First case of Zika in KY 2

Lab confirmed Zika in the U.S.A. 11 FEBRUARY CONUS Total of 52 travel associated cases 17 states US Territories 173 locally acquired cases 1 travel associated cases 9 MARCH CONUS Total of 193 travel associated cases 32 states US Territories 173 locally acquired cases 1 travel associated cases ZIKV Transmission Primary route of infection is via bite of infected mosquito 3

ZIKV Transmission (continued) http://emergency.cdc.gov/coca/ppt/2016/01_26_16_zika.pdf Mosquitoes that Carry ZIKV Aedes aegypti Aedes species known as container mosquitoes and are aggressive daytime biters Aedes albopictus Probable competent vector Known to be infected with Zika Currently, no documentation of transmission Found throughout Kentucky and most states Aedes albopictus Aedes aegypti mosquito Known competent vector Is common in warm climates including Africa, Asia, South America, Central America, the Caribbean, and the Southeast U.S. and we do have some in Kentucky 4

Clinical Features About 20% people infected develop symptoms/ 80% i t ti 80% remain asymptomatic Incubation period 2 12 days Maybe longer Characteristic clinical findings: fever, rash, arthralgia, or conjunctivitis. Clinical illness is usually mild with symptoms lasting for several days to a week Severe disease is uncommon Hospitalization rare Two neurological conditions associated with Zika infection in Brazil and other countries: Microcephaly Guillain Barre syndrome Recommendations for Testing History of travel to Zika affected area AND Symptomatic within two weeks of travel Travel during pregnancy Infants born to mom with positive or inconclusive test for Zika virus 5

Kentucky Testing as of 15 MAR 2016 Total tests approved = 51 pp 42 females symptomatic 4pregnant 9 Males Thus far, tests resulted from CDC One positive ZIKV Educate Travelers Prior to U.S. Departure Educate all travelers to wear mosquito repellent for one two weeks after return from travels. Best way to prevent Zika virus infection is to avoid mosquito bites by avoiding exposure and eliminating mosquito breeding areas. Educate male travelers to wear condoms after departure from Zika affected area for a time period or for the duration of pregnancy of sexual partner Until more is known, pregnant women should consider postponing travel to any area with active Zika virus transmission Healthcare providers should contact their state or local health departmentabout about testing patients with compatible travel history and symptoms for Zika Educate prevention and control measures Removal and modification of mosquito breeding sites Reducing contact between mosquitoes and people 6

References Zika Virus Outbreak on Yap Island, Federated States of Micronesia http://www.nejm.org/doi/pdf/10.1056/nejmoa0805715 World Health Organization Western Pacific Region http://www.wpro.who.int/mediacentre/factsheets/fs_05 182015_zika/en/ CDC http://www.cdc.gov/zika/index.html Coca Clinician Outreach and Communication Activity http://emergency.cdc.gov/coca/ppt/2016/01_26_16_zika.pdf Questions? Contact information: Shelley M. Wood, RN, BSN, CEN Reportable Diseases Section Infectious Disease Branch KY Department for Public Health shelleym.wood@ky.gov 502.564.3261 EXT. 4242 7