Optimising Perioperative Pain Management And Surgical Outcomes

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Optimising Perioperative Pain Management And Surgical Outcomes Dr Chew Ghee Kheng MBBS FRCOG MD FAMS Senior Consultant Gynaecologist Subspecialist in Gynaecology Oncology Surgery Singapore General Hospital

Background Originally pioneered by Professor Henrik Kehlet, Copenhagen, as the Multimodal approach Became widely popular in Europe

Background In 2002, NHS Institute for Innovation set up several centres to develop the Enhanced Recovery Programme

Aims of Enhanced Recovery Better outcomes and reduced length of stay Increased numbers of patients being treated (if there is demand) or reduced level of resources necessary Better staffing environment.

Enhanced Recovery Improving patient outcomes and speeding up a patient's recovery after surgery Pre-op assessment and preparation before admission Reducing physical stress of operation Post op and peri-op management Early mobilisation

Pre-op assessment and preparation before admission Attend Pre-op Assessment Clinic on same day of clinic where possible. Patients needing consultant anaesthetist opinion are identified on the same day. Any relevant investigations can be organised in timely fashion. Patients are optimised for their surgery Patient informed of Enhanced Recovery Programme at clinic once decision to operate made Admit on day of surgery.

Reducing physical stress of operation: To bowel prep or not to bowel prep... Preoperative bowel preparation for patients undergoing elective colorectal surgery: a clinical practice guideline endorsed by the Canadian Society of Colon and Rectal Surgeons Eskicioglu C 1, Forbes SS, Fenech DS, McLeod RS; Best Practice in General Surgery Committee. Conclusion: Taking into account the lack of difference in postoperative infectious complication rates when MBP is omitted and the adverse effects of MBP, we believe that, based on the literature, MBP before surgery should be omitted.

NICE: Cochrane Quality and Productivity topics Mechanical bowel preparation for elective colorectal surgery Summary NICE summary of review conclusions Evidence shows that mechanical bowel preparation is not effective for improving outcomes in patients undergoing elective colorectal surgery and should not be used routinely. It should be reserved for procedures in which intraoperative colonoscopy might be performed or close visualisation of the bowel mucosa is needed. Stopping or reducing the routine use of mechanical bowel preparation in patients undergoing elective colorectal surgery is likely to lead to improved quality of patient care, improved patient experience and productivity savings. Mechanical bowel preparation should still be used at the surgeon s discretion during procedures to identify pathology or when intraoperative colonoscopy might be performed. The Implications for practice section of the Cochrane review stated: Prophylactic mechanical bowel preparation prior to colorectal surgery has not been proven to be valuable for patients. This review suggested this should be abandoned. Bowel cleansing should be considered when a surgeon needs to identify pathology for example, a small tumour or when an intraoperative colonoscopy might be performed. In rectal surgery, prior to construction of an anastomosis, one of the surgical team can wash out possible bowel contents at the anal site of the anastomosis.

Complications of bowel preparation: Hypovolaemia Hypokalaemia Hyponatraemia Phosphate nephropathy (1:1000) Hypocalcaemia

Reducing physical stress of operation Reduce duration of fasting reduces the catabolic state. These high CHO drinks are not recommended for women with IDDM and NIDDM. Ann R Coll Surg Engl. Oct 2011; 93(7): 504 507. The role of carbohydrate drinks in preoperative nutrition for elective colorectal surgery C Jones, 1 SA Badger, 2 and R Hannon 1 The use of CHO drinks pre-operatively in colorectal surgery is both safe and effective. There is no increased risk of aspiration and It results in a shorter hospital stay, a quicker return of bowel function and less loss of muscle mass. On the basis of this evidence, the use of pre-operative CHO drinks should be standard in elective colorectal patients. Further research is nevertheless required for those with diabetes mellitus.

Close Fluid management Restrictive Fluid Use Hypotension Increased post-op nausea Inadequate Oxygen perfusion Impaired tissue oxygenation Liberal Fluid Use Interstitial oedema Poor wound healing Delayed gastric emptying Prolonged resumption in bowel emptying Fluid overload cardiac failure

Hypothermia Definition: core body temperature of less than or equal to 36 degrees Celsius or 96.8 degrees Fahrenheit Perioperative hypothermia can result in: three times the incidence of surgical site infection increased bleeding and increased need for blood transfusions three times the risk for cardiac complications a higher risk for developing pressure ulcers prolonged recovery after surgery

Surgeon in OT in UK Surgeon in OT is Singapore

Peri and post-op analgesia Regional block reduces intraop and immediate post op opiate requirements. (Morphine requirements in the first 24 postoperative hours were also reduced (21.9 8.9 mg vs 80.4 19.2 mg, P 0.05) McDonnell J et al The Analgesic Efficacy of Transversus Abdominis Plane Block after Abdominal Surgery : A Prospective Randomised Control Trial. Anaesthesia and Analgesia. 2007, V104(1):193-7 Reduced opiates means less nausea and bowel dysmotility NSAID and Paracetamol regularly unless contraindicated (suppositories can be given regularly immediately post op until oral intake tolerated)

Early Re-feeding Traditional practice is to keep patients with bowel anastomotic surgery with NG tube nil by mouth is not based on evidence based practice Free fluids immediately post op. Light diet Day1

Early mobilisation Patients are encouraged to sit in a chair or mobilise on the day of surgery Mobilisation on Day 1. Glycerin supp Day 2 to encourage bowel activity Remove all drains and catheters as early as possible

Practical Aspects Staff training and learning Improved processes Procedure specific care plans Change of mindset: patient, doctors, care givers

How Multidisciplinary team Education staff, patients, mindsets Map patient journey - identify needs Implementation Audit identify problems, patient satisfaction Readmission rate- how to prevent

SGH Gynaecology Experience

Discharge within 7 days post OP 100% 95% 90% Rate of discharge within 7 days post OP 85% 80% 75% 70% 65% 60% 55% 50% 45% 40% Median = 92.31% 08-12W1 08-12W2 08-12W3 08-12W4 09-12W1 09-12W2 09-12W3 09-12W4 10-12W1 10-12W2 10-12W3 10-12W4 11-12W1 11-12W2 11-12W3 11-12W4 12-12W1 12-12W2 12-12W3 12-12W4 N 20 8 9 39 12 12 21 26 19 21 14 27 15 11 15 33 22 19 19 14 D 24 10 11 40 13 13 23 29 20 21 15 30 17 12 16 34 23 19 19 14 Rates 83.33% 80.00% 81.82% 97.50% 92.31% 92.31% 91.30% 89.66% 95.00% 100.00% 93.33% 90.00% 88.24% 91.67% 93.75% 97.06% 95.65% 100.00% 100.00% 100.00% Indicators Numerator Denominator Inclusion criteria Exclusion criteria Source Discharge within 7 days post OP All major Gynaecological cases with LOS 7 days All Gynaecological cases All Major matching operation codes for Gynaecological cases major cases All surgery cases done in SGH

How Laparoscopic Surgery where possible The team is encouraged to adopt a different mind-set in managing patients in the pre and post-operative period Patients are encouraged to adopt this pro-active mindset, from the moment they agree to the surgery. Patients are given pre-op high carbohydrate load drinks Anaesthetists to use a different regime of anaesthetic/ analgesics, involving less opiates. Early establishment of oral intake and mobilisation Discharge when patients are ready.

Measures Length of stay Patient satisfaction

Discharged within 4 days post op Rate of discharge within 4 days post OP 100% 95% 90% 85% 80% 75% 70% 65% 60% 55% 50% 45% 40% 35% 30% 25% 20% 15% 10% 5% 0%

Early mobilisation and re-feeding

Length of stay - baseline 100% 95% 90% 85% 80% Rate of discharge within 4 days post OP 75% 70% 65% 60% 55% 50% 45% 40% 35% 30% 25% 20% 15% 10% 5% 0% 08-12W1 08-12W2 08-12W3 08-12W4 09-12W1 09-12W2 09-12W3 09-12W4 10-12W1 10-12W2 10-12W3 10-12W4 11-12W1 11-12W2 11-12W3 11-12W4 12-12W1 12-12W2 12-12W3 12-12W4

Introduction of regular non-opiate analgesics

Introduction of Pre-op drinks

no Laparotomy Laparoscopy Abscess 3 3 Advanced rectal ca 6 6 Ovary (borderline /benign) 6 5 1 Cervical/vaginal cancer?ais 11 10 2 Endometrial cancer 28 16 12 Endometriosis 6 5 1 Fibroid 11 11 IDS (ovary ca) 8 8 Krukenberg 5 5 Ovary /fallopian tube ca 25 25 Peritoneal ca 3 3 Pelvic exanteration 1 1 Sarcoma 4 4

Discharged on Post op day Laparoscopy 1 3 Laparotomy 2 6 2 3 6 24 4 1 22 5 14 6 10 7 6 >7 22 + 2 (died) LOS 4 = 64/118 = 54%

Patient Satisfaction (Telephone exercise by Service Quality Staff) Two hundred and seventy two phone calls were made, of which they were not able to contact 39 of the patients (2 of whom had returned to their own country). 3 main questions: If they felt their post op analgesia was sufficient If they felt that their hospital stay was the correct length If they were satisfied with their care pre-op counselling and hospital stay

If they felt their post op analgesia was sufficient Post Op pain relief Yes No Pain well controlled 219 14 Enough pain medication 231 2

If they felt that their hospital stay was the correct length Length of Stay No. patients Too Short 8 Just Right 169 Too Long 13 No comments 43

If they were satisfied with their care pre-op counselling and hospital stay Satisfied with hospital care No. Patients Satisfactory 9 Good or very good 213 No comments 1

So I ask you: Would you rather look like this

Or this..

Thank you very much for listening