Cutaneous Lymphoid Proliferations: A Comprehensive Textbook of Lymphocytic Infiltrates of the Skin

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Cutaneous Lymphoid Proliferations: A Comprehensive Textbook of Lymphocytic Infiltrates of the Skin Magro, Cynthia M., MD ISBN-13: 9780471695981 Table of Contents Chapter One: Introduction to the Classification of Lymphoma (Martin C. Mihm, Cynthia M. Magro, and A. Neil Crowson). Kiel, Lukes Collins, and Working Formulation Classifications. WHO, Real, and EORTC Classifications. Summary. Appendix: Definitions of Key Terms and Techniques. Chapter Two: The Therapy of Cutaneous T Cell Lymphoma (Pierluigi Porcu and Mark A. Bechtel). Diagnostic Work-up and Staging Procedures. Goals of Therapy in Advanced Stage CTCL. Extracorporeal Photopheresis (ECP). Interferons. Retinoids. Immunotoxins. Monoclonal Antibodies. Cytotoxic Chemotherapy. Investigational Therapies. Monoclonal Antibodies. TLR Agonists and Cytokines. Histone Deacetylase Inhibitors (HDACi). Allogeneic Hematopoietic Stem Cell Transplantation (allo-hsct). CTCL Therapies. Skin-Directed Therapies. Chapter Three: Molecular Techniques (Carl Morrison). Immunoglobulin Receptor Structure. IgH. TCR-β. PCR Design for Determination of Clonality. Detection of PCR Products for Clonality.

Evaluation of Results. Limitations of Clonality Assessment by PCR. Summary. Chapter Four: Benign Lymphocytic Infiltrates Spongiotic and Eczematous Dermatitis. Allergic Contact Dermatitis. Pityriasis Rosea. Pityriasis Rosea-like Drug Reaction. Other Spongiotic/Eczematous Tissue Reactions. Photoallergic Reactions. Other Causes of Subacute Eczematous Dermatitis. Nummular Eczema. Small Plaque Parapsoriasis. Pruritic Urticarial Plaques and Papules of Pregnancy. Superficial Erythema Annulare Centrifugum. Interface Dermatitis: Cell-Poor Vacuolar Interface Dermatitis. Erythema Multiforme. Gianotti Crosti Syndrome (Popular Acrodermatitis of Childhood). Acute Graft-Versus-Host Disease. Morbiliform Viral Exanthem and Morbiliform Drug Eruption. Collagen Vascular Disease Compatible with Antibody-Dependent Cellular Immunity and/or Anti endothelial Cell Antibodies. Interface Dermatitis: Lichenoid Pattern. Lichen Planus. Lichen Planus-like Eruptions of Hepatobiliary Disease. Lichen Planus-like Eruptions of Secondary Syphilis. Lichenoid Drug Reactions. Lichenoid Connective Tissue Disease Syndromes. Lichenoid ( Chronic ) Graft-Versus-Host Disease. Diffuse and Nodular Lymphocytic Dermal Infiltrates Without Atypia. Polymorphous Light Eruption as the Prototypic Type IV Immune Reaction. Other Dermal Perivascular Lymphocytic Infiltrates. Gyrate Erythemas. Diffuse and Nodular Lymphocytic Infiltrates Associated with Autoimmune Disease. Nonscarring Discoid Lupus Erythematosus/Tumid Lupus Erythematosus. Morphea.

Jessner s Lymphocytic Infiltrate of the Skin. Chapter Five: Reactive Lymphomatoid Tissue Reactions Mimicking Cutaneous T and B Cell Lymphoma (Cynthia M. Magro and A. Neil Crowson). Lymphomatoid Drug Eruptions. Molecular Profile of Lymphomatoid Drug Eruptions. Pathogenetic Basis of Lymphomatoid Drug Reactions. Reactive Lymphomatoid Lesions Encountered in Lesions of Collagen Vascular Disease. Lymphomatoid Lupus Erythematosus. Pathogenesis of Lymphomatoid Tissue Response in Collagen Vascular Disease. Lupus Erythematosus Profundus. Viral-Associated Lymphomatoid Dermatitis. Lymphocytoma Cutis. Primary Cutaneous Plasmacytosis. Conclusion. Chapter Six: Precursor Lesions of Cutaneous T Cell Lymphoma (Cynthia M. Magro, Joan Guitart and A. Neil Crowson). Cutaneous T Cell Lymphoid Dyscrasia. Large Plaque Parapsoriasis. Hypopigmented Epitheliotropic T Cell Dyscrasia/Hypopigmented Large Plaque Parapsoriasis as a Precursor Lesion to Hypopigmented Mycosis Fungoides. Pigmented Purpuric Dermatosis (PPD). Pityriasis Lichenoides Chronica. Syringolymphoid Hyperplasia with Alopecia. Idiopathic Follicular Mucinosis/Alopecia Mucinosa. Atypical Lymphocytic Lobular Panniculitis. Chapter Seven: Marginal Zone Lymphoma and Other Low-Grade B Cell Lymphoproliferative Disorders of the Skin Marginal Zone Lymphoma. Castleman s Disease. Primary Cutaneous Plasmacytoma. Chapter Eight: Primary Cutaneous Follicle Center Cell Lymphoma

Additional Molecular and Cytogenetic Study. Chapter Nine: Primary Cutaneous Diffuse Large B-Cell Lymphoma and Precursor Lymphoblastic Lymphoma Primary Cutaneous Diffuse Large B-Cell Lymphoma. Cutaneous Precursor B Cell Lymphoblastic Lymphoma/Lymphoblastic Leukemia (Precursor B Cell Acute Lymphoblastic Leukemia. Chapter Ten: Intravascular Lymphoma Chapter Eleven: Chronic Lymphocytic Leukemia of B Cell and T Cell Phenotype (T Cell Prolymphocytic Leukemia) B Cell Chronic Lymphocytic Leukemia. T Cell Prolymphocytic Leukemia. Chapter Twelve: Cutaneous Mantle Cell Lymphoma Chapter Thirteen: Primary Cutaneous γ δ T Cell Lymphoma Chapter Fourteen: Mycosis Fungoides (Cynthia M. Magro, Martin C. Mihm, and A. Neil Crowson). Definition. Historical Perspective. Demographics. Clinical Presentation. Patch Stage. Plaque Stage. Tumor Stage. Extracutaneous Dissemination. Clinical Variants. Papuloerythroderma. Mycosis Fungoides in Childhood.

Adnexotropic Mycosis Fungoides. Woringer Kolopp Disease (Pagetoid Reticulosis). Granulomatous Slack Skin/Granulomatous Mycosis Fungoides. Sezary Syndrome. Extracutaneous Involvement in Mycosis Fungoides. Phenotypic Profile. Molecular Profile. Cytogenetics. Pathogenesis. References, 297 Chapter Fifteen: Primary Cutaneous Pleomorphic Small/Medium Sized T-Cell Lymphoma And Peripheral T-Cell Lymphoma, Unspecified, Presenting in the SKIN (CD30-Negative Large Cell T Cell Lymphoma) (Cynthia M. Magro and A. Neil Crowson). Additional Molecular and Cytogenetic Study. Chapter Sixteen: Adult T Cell Leukemia/Lymphoma (Cynthia M. Magro). Chapter Seventeen: Angioimmunoblastic Lymphadenopathy (AILD)/Angioimmunoblastic T Cell Lymphoma Chapter Eighteen: CD8 T Cell Lymphoproliferative Disease of the Skin Primary Cutaneous CD8 Lymphoma. CD8 Variant of Lymphomatoid Papulosis and Other Related CD30-Positive T Cell Lymphoproliferative Disorders of CD8 Subtype. CD8 Prolymphocytic Leukemia. CD8 Pseudolymphoma Related to Underlying HIV Disease. CD8 Cytotoxic Pseudolymphoma Related to Drug Therapy. Chapter Nineteen: Subcutaneous Panniculitis-Like T Cell Lymphoma Chapter Twenty: Epstein Barr Virus-Associated Lymphoproliferative Disease (Cynthia M. Magro and A. Neil Crowson).

Hydroa Vacciniforme-Like EBV-Associated T Cell Lymphoproliferative Disease/Mosquito Bite Hypersensitivity. Epstein Barr Virus-Associated B Cell Lymphoproliferative Disease in the Setting of Iatrogenic Immune Dysregulation. Chapter Twenty-One: Nasal and Related Extranodal Natural Killer Cell/T Cell Lymphomas (Cynthia M. Magro and A. Neil Crowson). Biology of NK and NK-like T Cells. NK/T-Cell Lymphoma. Nasal NK/T-Cell Lymphoma. Nasal Type NK/T Cell Lymphoma. Aggressive NK Cell Lymphoma. Role of Epstein Barr Virus in the Evolution of NK/T Cell Lymphomas. Blastic/Blastoid NK Cell Lymphoma/Agranular CD4-positive CD56-positive Hematodermic Neoplasm. Panniculitis-like T Cell Lymphoma Showing CD56 Positivity. Chronic Granular Lymphocytosis/Large Granular Cell Leukemia. Natural Killer-like T Cell Lymphoma of the CD4 Subset: A Rare Variant of Natural Killer Cell Lymphoma to Be Distinguished from the Hematodermic Neoplasm. Chapter Twenty-Two: Lymphomatoid Granulomatosis (LYG) Chapter Twenty-Three: CD30-Positive Lymphoproliferative Disorders Including Lymphomatoid Papulosis, Borderline CD30-Positive Lymphoproliferative Disease, Anaplastic Large Cell Lymphoma, and T-Cell-Rich CD30- Positive Large B Cell Lymphoma Lymphomatoid Papulosis. CD8 Lymphomatoid Papulosis. Borderline CD30-Positive Lymphoproliferative Disorders (Type C LYP) (Case Vignette 9). Cutaneous Anaplastic Large Cell Lymphoma. CD30-Positive Large B Cell Lymphoma. Chapter Twenty-Four: Primary Cutaneous Hodgkin Lymphoma (Cynthia M. Magro). Subtypes of Hodgkin Lymphoma. Classic Hodgkin Lymphoma.

Lymphocyte-Predominant Hodgkin lymphoma. Index.

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