APCASH 2011 Scientific Program. Time Title Speaker 07:30 08:00 Registration

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Main Conference Saturday 8 January 2011 Ballroom, 3/F, Sheraton Hong Kong Hotel and Towers 07:30 08:00 Registration 07:45 09:00 Best Abstract Competition Judges: Kam-Tim Chan (Hong Kong), Yat-Yin Lam (Hong Kong), Maurice P Leung (Hong Kong) 07:45 07:57 Device Selection without Balloon Sizing Technique in Patients with Large ASD: Clinical Efficacy of Real Time 3 Dimensional Transesophageal Echocardiography Kijima Yasufumi (Japan) 07:57 08:10 The closure of a 2 atrial septal defect using an Amplatzer device without a balloon sizing method Jinyoung Song (Korea) 08:10 08:22 Prevalence and Determinants of Incomplete Right Atrial Reverse Remodeling at Mid-term following Device Closure of Atrial Septal Defects Fang Fang (Hong Kong) 08:22 08:34 Persistent Proximal Hypertension (PHBP) Post COA - Role of the Hypoplastic Arch (HA) Tiow Hoe Goh (Australia) 08:34 08:46 Visualization of the Left Atrial Appendage in 3-Dimensions: Complex Anatomy and Structure in Multidetector CTA as an aid to Percutaneous Closure Strategies Hidehiko Hara (Japan) 08:46 08:58 Left Atrial Appendage Closure with Amplatzer Cardiac Plug for Stroke Prevention in Atrial Fibrillation: Initial Asia-Pacific Experience Byran Yan (Hong Kong) 09:00 10:30 Live Case Transmission from Jiangsu Province Hospital - I Chairpersons: Maurice P Leung (Hong Kong), Shu-Kin Li (Hong Kong) Panelists: Boron CW Cheng (Hong Kong), Shui-Wah Chiu (Hong Kong), Lan Hieu Nguyen (Vietnam), Fen Li (China) 09:00 09:20 Complications in Congenital Heart Disease Interventions Anita Saxena (India) 09:20 10:10 Dicussion of Live Case Perimembranous VSD Xiang-Qing Kong (China) 10:10 10:30 Taped CASH Case New VSD Occluder PFM Coil Lan Hieu Nguyen (Vietnam) 10:30 11:00 Tea Break & Visit Exhibits 1

11:00 12:00 Live Case Transmission from Jiangsu Province Hospital II Chairpersons: Adolphus KT Chau (Hong Kong), Jou-Kou Wang (Taiwan) Panelists: Hong Gu (China), Dora ML Wong (Hong Kong), Man-Ching Yam (Hong Kong) 11:00 11:15 Closing the Ductus in the Presence of Pulmonary Hypertension Seong-Ho Kim (Korea) 11:15 12:00 Discussion of Live Case Large Patent Ductus Arteriosus Xiang-Qing Kong (China) 12:00 13:00 ASD Occlusion Chairpersons: Adolphus KT Chau (Hong Kong), Wing-Hing Chow (Hong Kong), Vincent OH Kwok (Hong Kong), Kin-Ming Tam (Hong Kong), Ping-Tim Tsui (Hong Kong), Gabriel WK Yip (Hong Kong) 12:00 12:15 Anatomy and 3D Imaging of ASD and Placement of the Occlusion Device Toshio Nakanishi (Japan) 12:15 12:30 Can we anticipate Which are the Difficult-to-close ASDs? Clinical Implication of Real-time 3 Dimensional Transesophageal Echocardiography Manabu Taniguchi (Japan) 12:30 13:00 Taped CASH Case Large ASD with Minimal Rims Yee-Guan Yap (Malaysia)*TBC 13:00 13:45 Lunch (Venue: Sky Lounge, 18/F) 13:45 14:00 APCASH 2010 Opening Ceremony 14:00 15:15 Live Case Transmission from Rigshospitalet, Copenhagen, Denmark I Chairpersons: Wilson WM Chan (Hong Kong)*TBC, Michael KY Lee (Hong Kong) Panelists: Kin-Wing Chan (Hong Kong), Liang Chow (Hong Kong), Wing-Hung Chui (Hong Kong), Steven SL Li (Hong Kong) 14:00 14:20 Transcatheter Aortic Valvular Implantation (TAVI) Current Developments Reda Ibrahim (Canada) 14:20 14:35 TAVI Hong Kong Experiences Michael KY Lee (Hong Kong) 14:35 15:15 Discussion of Live Case CoreValve 15:15 16:00 Live Case Transmission from Rigshospitalet, Copenhagen, Denmark II Chairpersons: Kam-Tim Chan (Hong Kong), Yat-Yin Lam (Hong Kong) Panelists: Kwok-Keung Ho (Hong Kong), Reda Ibrahim (Canada), Kin-Lam Tsui (Hong Kong) Lars Sondergaard/ Niels Vejlstrup (Denmark) 15:15 15:30 Investigational Devices for Mitral Regurgitation: State-of-the-Art Gerald Yong (Australia) 2

15:30 16:00 Discussion of Live Case MitraClip 16:00 16:30 Tea Break & Visit Exhibits (Concurrent with Live Transmission Sessions) 16:00 17:00 Live Case Transmission from Rigshospitalet, Copenhagen, Denmark III Olaf Franzen/ Nikolaj Ihlemann (Denmark) Chairpersons: Adam WH Leung (Hong Kong),Yuk-Kong Lau (Hong Kong), Tak-Sun Tse (Hong Kong), Chris KY Wong (Hong Kong), Eugene Wu (Hong Kong) 16:00 16:15 Shall we Close Patent Foramen Ovale in Young patients with Cryptogenic Stroke? Reda Ibrahim (Canada) 16:15 16:45 Discussion of Live Case - PFO closure (Occlutech) Olaf Franzen/ Niels Vejlstrup (Denmark) 16:45 17:00 Preclinical in Vivo Evaluation of the FuStarTM Steerable Introducer in a Porcine Model Wei-Feng Lu (China) 18:45 Faculty Dinner and Awards Presentation of Best Abstract Competition (By invitation) Venue: Serenade Chinese Restaurant, Hong Kong Cultural Centre, Tsim Sha Tsui, Kowloon * Pick-up at Bell Desk, G/F of Sheraton Hong Kong Hotel & Towers at 18:30 CASH Symposium for Allied Health Professionals Saturday 8 January 2011 Tang Room, 3/F, Sheraton Hong Kong Hotel and Towers 14:30 16:00 CASH Made Easy I Chairpersons: Anna KY Chan (Hong Kong), Kin-Ming Tam (Hong Kong) 14:30 14:50 Interventional Cardiovascular Imaging for CASH Interventions Gabriel WK Yip (Hong Kong) 14:50 15:10 Stroke Prevention Strategies for AF Patients Drugs and Devices? Chin-Pang Chan (Hong Kong) 15:10 15:30 Management of ASD and PFO Jason LK Chan (Hong Kong) 15:30 15:50 How to Implant an Aortic Valve Percutaneously? Michael KY Lee (Hong Kong) 3

Free Paper (Oral) Presentation Sunday 8 January 2010 Tang Room, 3/F, Sheraton Hong Kong Hotel and Towers 08:00-09:00 Free Paper (Oral) Presentation Chairpersons: Boron CW Cheng (Hong Kong), Kwok-Keung Ho (Hong Kong) 08:00 08:12 The Effect of 17β-Estradiol on Oxidative Stress-induced Apoptosis and Its regulatory mechanism in H9c2 Cells 08:12 08:24 Effects of Nerve Growth Factor on Action Potential and Potassium Currents in the infarcted rabbit ventricle 08:24 08:36 Molecular Mechanism and Characterization of Maternally Inherit of Essential Hypertension 08:36 08:48 Fragmented QRS on Twelve-Lead Electrocardiogram Predicts The Malignant Ventricular Arrhythmia in Patients With Acute Myocardial Infarction 08:48 09:00 Hemodynamics characteristics of iptakalim hydrochloride, a new potassium channel opener, in anesthetized nomotensive canine model Zong Bin Li (China) *TBC Kun Lin (China) *TBC Shi Wen Wang (China) *TBC Jing Wang (China) Qing lei Zhu (China) *TBC 4

Main Conference Sunday 9 January 2010 Ballroom, 3/F, Sheraton Hong Kong Hotel and Towers 08:25 09:00 Registration LAA Occlusion Symposium * Sponsored by St. Jude Medical * 09:00 10:00 Chairpersons: Joseph YS Chan(Hong Kong), Ngai-Yin Chan (Hong Kong), Wilson WM Chan (Hong Kong)*TBC, Wing-Hong Fung (Hong Kong), Francis SF Yiu (Hong Kong)*TBC 09:00 09:25 Role of TEE in Guiding Transcatheter LAA Occlusion Yat-Yin Lam (Hong Kong) 09:25 10:00 Taped CASH Case Left Atrial Appendage Occlusion (LAAO) using the Cardiac Plug Reda Ibrahim (Canada) 10:00 10:30 Tea Break & Visit Exhibits Mitral Valve, Paravalvar Leak and VSD Interventions 10:30 12:10 Chairpersons: Chung-Seung Chiang (Hong Kong)*TBC, Duncan HK Ho (Hong Kong), Sum-Kin Leung (Hong Kong), Kai-Fat Tse (Hong Kong) 10:30 10:55 Role of TEE in Percutaneous Mitral Valve Interventions Gabriel WK Yip (Hong Kong) 10:55 11:20 Taped CASH Case Paravalvar Leak Reduction using the Vascular Plug III Reda Ibrahim (Canada) 11:20 11:45 Taped CASH Case Can we go on? Yes or No? Transcatheter Closure in the Perimembranous Ventricular Septal Defect (PMVSD) using Symmetry Devise Hui-Shen Wang (China) 11:45 12:10 Transcatheter Closure PmVSD: Using Domestic VSD Occluder (A Single Centre Experience) Zhen-Fei Fang (China) 5

Lunch Symposium (Venue: Sung Room, 4/F) * Sponsored by Pacific Medical Systems Ltd / GE Healthcare * Let s Have a Look (with the Vscan )! A Pocket-sized Visualization Tool for Point-of-care Imaging Lea Anne Danton (USA) Lunch Symposium (Venue: Ming Room, 4/F) * Sponsored by Lifetech Scientific Co. Ltd. * 12:10 13:10 A Prospective, Multicenter, Randomized trial to Assess Efficacy and Safety of the CERA TM Occluder in Congenital Heart Disease (ASD/VSD/PDA): CERA TRIAL Yu-Mei Xie (China) Wei Feng Lu (China) / Use of Vascular Occluder to Treat Re-Entry Tear in Stanford Type B Aortic Dissection: Animal Experiments and Clinical Trials Xiao Tang (China) Transcatheter Aortic Valvular Implantation (TAVI) 13:10 14:10 Chairpersons: Elaine MC Chau (Hong Kong), Chung-Seung Chiang (Hong Kong)*TBC, Steven SL Li (Hong Kong), Gary YK Mak (Hong Kong) 13:10 13:45 Taped CASH Case Transcatheter Aortic Valvular Implantation (TAVI) Anna Sonia Petronio (Italy) 13:45 14:10 Management of TAVI Complications Gerald Yong (Australia) Learn from the Experts 14:10 15:25 Chairpersons: Boron CW Cheng (Hong Kong), Chun-Ho Cheng (Hong Kong), Reda Ibrahim (Canada), Vincent OH Kwok (Hong Kong), Yat-Yin Lam (Hong Kong), Steven SL Li (Hong Kong), 14:10 14:35 Secundum ASD and Pulmonary Hypertension in an Elderly Patient Jou-Kou Wang (Taiwan)/ Gerald Yong (Australia) 14:35 15:05 A Patient with Functional MR Alex PW Lee (Hong Kong)/ Kwok-Keung Ho (Hong Kong)/ Gerald Yong (Australia) 15:05 15:30 Degenerative AS in a Patient with Difficult Peripheral Vascular Access Gerald Yong (Australia)/ Anna Sonia Petronio (Italy) 15:00 15:30 Tea Break & Visit Exhibits (Concurrent with Learn from the Experts) 6

Best Clinical Case Competition 15:30 17:00 Judges: Chung-Seung Chiang (Hong Kong)*TBC, Reda Ibrahim (Canada), Patrick TH Ko (Hong Kong), Anna Sonia Petronio (Italy) 15:30 15:45 A Case of persistent hypoxia after inferior AMI Gary SH Cheung (Hong Kong) 15:45 16:00 Dynamic Left Main Coronary Artery Obstruction: To Treat or Not to Treat? Byran Yan (Hong Kong) 16:00 16:15 A patient with ST-segment elevated myocardial infarction complicating left atrial appendage occlusion Anna KY Chan (Hong Kong) 16:15 16:30 Percutaneous Closure of Coronaryaneurysm Lau Chun Leung (Hong Kong) 16:30 16:45 Home made stent in RVOT of post op TOF Jinyoung Song (Korea) CASH Symposium for Allied Health Professionals Sunday 9 January 2010 Tang Room, 3/F, Sheraton Hong Kong Hotel and Towers CASH Made Easy II 10:00 11:30 Chairpersons: Stephen CC Choy (Hong Kong), Leo CC Kum(Hong Kong), John TH Wong (Hong Kong) 10:00 10:20 Role of Echocardiography in Assessment of Valvular Heart Disease Alex PW Lee (Hong Kong) 10:20 10:40 Surgical Treatment for Valvular Heart Disease Kwok-Keung Ho (Hong Kong) 10:40 11:00 How to do a Transseptal Puncture Safely? Steven SL Li (Hong Kong) 11:00 11:20 Percutaneous Therapy for Mitral Valve Disease Wilson WM Chan (Hong Kong)*TBC 7