WEST EURASIA FMD LAB PHASE ACTIVITY PROPOSAL. A. Naci BULUT Head of the Diagnosis Department, Şap Institute

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WEST EURASIA FMD LAB NETWORK WELNET FMD- 2ND PHASE ACTIVITY PROPOSAL FAO/the EuFMD Commission, 39th General Session, 27/28 April 2011 Rome, Italy A. Naci BULUT Head of the Diagnosis Department, Şap Institute

Background of West Eurasia FMD Lab Network (WELNET FMD) In the 1 st Regional Workshop: it was recommended establish a laboratory network under the West Eurasia Roadmap Organization. Aimed: promote better communication, improvement early detection, diagnostic capacity and performance of laboratories and also implementing a system for proficiency testing Last year, 2010, 1st phase activities were realized: Training on Laboratory Diagnostic Methods of FMDV Organization regular quarterly teleconference meeting End of the year evaluation meeting Gap on the proposed activities (not realized): Technology transfer for gap on the diagnostic methods of the PCP member laboratories Providing services on laboratory tests for early detection of the disease Workshop for Quality Assurance (QA) for laboratory test and laboratory Organization of lab proficiency test scheme 2

RECOMMENDATION OF THE WELNET FMD BY 2nd REGIONAL PROGRESS REVIEW MEETING Support is provided to WELNET in 2011 to better plan activities and achieve regular communication between the reference and national laboratories in the region; Comprehensive plan to address the training needs over the next three years, should be developed, it required supported by FAO consultancy; First priority is to achieve a rapid and sensitive means of confirming the FMD serotype in all countries, and secondary to achieve the capacity to undertake NSP (stage1) and SP (stage2) needed to countries according to their stage in the PCP; That the Annual Workplan for 2011 be considered and supported by EuFMD and/or the other international agencies, and calls upon the EuFMD to provide support for the action plan; Actions to harmonize quality of reporting of suspected vaccination failure (WELNET protocol for investigating suspected vaccine failure, developed with the Epinetwork and pilot study in at least two countries; More work on the stability of type O vaccine strains, and duration of immunity various type O vaccines used in the region; Develop a simple PTS to be serviced within the region, with results that can be brought back to the Annual Meeting. 3

WELNET FMD 2ND PHASE WORKPLAN PROPOSAL FOR 2011 4

Activities for Annual plan for 2011 1. Organization of lab proficiency test scheme Shall be conducted annually in the third quarter of the year: Panels shall be prepared and service for delivering panels and organization of the study shall be provided by Şap Institute (leadership of lab network). serological and virological panel shall be identified according to the minimum lab methods capacities required to their stage. The analyzed results shall be evaluated in the meeting to be held on end of the year. Provide harmonized, more precised and reliable test methods which service for effective control strategy in the region 5

Activities for Annual plan for 2011(2) 2. Organization regular quarterly teleconference and Annual Evaluation Meeting Teleconference meetings shall be conducted as possible as time remained of the year Annual Evaluation Meeting: It will be held on a face to face evaluation meeting end of the year which will be evaluated all activities of the region and planned topics of next year 6

Activities for Annual plan for 2011(3) 3.Training on Laboratory Diagnostic Methods of FMDV Shall be conducted training according to outputs of comprehensive training plan identified specifically subjects on FMD diagnostic methods That will be covered needs on gaps of each laboratory Available topics: methods for typing of FMDV, serology of FMDV (LPBE,NSP and VNT), methods for virus characterization and methods for molecular epidemiology as theoretical and practice Provide a effective capacity building on diagnostic methods in order to supply diagnostic services which need for each stage of PCP 7

Activities for Annual plan for 2011(4) 4.Follow-up training for gap on the diagnostic methods of the WELNET FMD member laboratories Provide achievement test methods establishment in host laboratories in order to maintain sustainable test system 39th General Session of the EuFMD Commission, 27/28 April 2011 Rome, Italy 8

Activities for Annual plan for 2011(5) 5. Providing services on laboratory tests for early detection of the disease and vaccine matching Shall be supplied opportunity on molecular analysis (nucleotide sequencing ) test for field isolates received from endemic network countries by leadership laboratory At least 10 samples from each endemic country will be provided an enough data to understand existed disease situation Within the 15 days, the results will be available And also it could be possible to extent the same supplement for antigenic characterization test, if it would be made a decision as gap for the need. Pilot study on stability of serotype O vaccines A fiseability work will be done for duration of immunity various type O vaccines used in the region Provide an early and proper detection of FMDV which will be lead early identifying important epidemiological events in order to reach a new 9 stage of PCP