Current Topics in Breast Cancer Symposium

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Current Topics in Breast Cancer Symposium Friday, March 22, 2019 Wyndham Grand Hotel 600 Commonwealth Place 15222 Sponsored By Pittsburgh, Pennsylvania In collaboration with The Johns Hopkins Sidney Kimmel Comprehensive Cancer Center Baltimore, Maryland

Conference Overview This symposium will cover areas of recent advances and controversies related to breast cancer screening and detection, surgical, radiation, and medical breast cancer care. Following its presentation, participants should be able to identify new imaging technology for screening and detection, improved treatment methods addressing local and systemic therapies, advances, and concerns in a patient s quality of life, survivorship issues, and the personalized approach to care using molecular and genetic tools. Who Should Attend This course is designed for physicians, nurses, and other health care professionals practicing in the areas of Surgical, Medical, Radiation Oncology, Pathology, and General Surgery recommended for any practitioner caring for women. At the conclusion of this course, participants should be able to: Identify the existing standard of care treatments for breast cancer. Become familiar with evolving novel systemic treatments utilizing molecular and immunotherapy targeting of breast cancer. Understand the utility/importance of molecular assays. Describe the importance of clinical trials in the advancement of breast care treatments. Identify factors that affect patient quality of life and survivorship.

Conference Directors Christie Hilton, DO Division of Hematology and Oncology Thomas B. Julian, MD Professor of Surgery Drexel University College of Medicine Professor of Surgery Temple University School of Medicine Associate Medical Director of Cancer Program Development AHN Breast Surgical Oncology AHN NRG/NSABP PI-AHN Chair Communications NRG Oncology Keynote Speaker Alessandro Leal, MD PhD Candidate Laboratory of Cancer Genomics Sidney Kimmel Comprehensive Cancer Center School of Medicine Karen Lisa Smith, MD, MPH Assistant Professor of Oncology Breast and Ovarian Cancer Program Johns Hopkins Sidney Kimmel Cancer Center Jean L. Wright, MD Associate Professor Director, Breast Radiation Oncology Director, Safety and Quality Department of Radiation Oncology and Molecular Radiation Sciences

Faculty Fariba Asrari, MD Director, Johns Hopkins Breast Center at Green Spring Station Department of Radiation Oncology & Molecular Sciences Sara Alcorn, MD, MPH Assistant Professor Radiation Oncology and Molecular Radiation Sciences School of Medicine Diane Buchbarker, MD Division of Hematology and Oncology Melissa Camp, MD Assistant Professor of Surgical Oncology School of Medicine Roisin Connolly, MD, BCh, BAO Assistant Professor of Oncology School of Medicine Marielle Ferstenberg, DO Breast Surgical Oncology Fellow Lisa Jacobs, MD Associate Professor of Surgery School of Medicine Sarah Miller, DO Division of Hematology and Oncology Lisa Mullen, MD Assistant Professor of Radiology School of Medicine Raquel Nunes, MD Assistant Professor of Oncology The Sidney Kimmel Cancer Center Sibley Memorial Hospital

David S. Parda, MD, FACP Professor and System Chair Department of Oncology/, IRB Indu Poornima, MD Medical Director, Nuclear Cardiology Director, Women s Heart Center Jane Raymond, MD Division of Hematology and Oncology Evanthia Roussos Torres, MD, PhD Assistant Professor of Oncology Sidney Kimmel Comprehensive Cancer Center Jenni Sheng, MD Medical Oncology Fellow Sidney Kimmel Comprehensive Cancer Center Mark Trombetta, MD, FACR Professor of Radiation Oncology Drexel University College of Medicine System Director of Clinical Programs Anthony N. Wakim, MD, FACOG Reproductive Endocrinology Jean L. Wright, MD Associate Professor Director, Breast Radiation Oncology Director, Safety and Quality Department of Radiation Oncology and Molecular Radiation Sciences Cesar A. Santa-Maria, MD, MSCI Assistant Professor of Oncology Breast and Ovarian Cancer Program The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Conference Agenda 7:00 a.m. Registration, Continental Breakfast/Visit Exhibitors 8:00 a.m. 8:10 a.m. 8:30 a.m. Welcome/Introductions/Conference Goals Thomas B. Julian, MD; Christie Hilton, DO; Karen Lisa Smith, MD; Jean L. Wright, MD AHN-JHU Update David Parda, MD Keynote Characterization of Cancer Using Noninvasive Liquid Biopsies Alessandro Leal, MD Session 1 DCIS-Local Therapy Moderator: Diane Buchbarker, MD 9:00 a.m. 9:15 a.m. 9:30 a.m. Current Issues in Management of DCIS: Surgical Considerations Marielle Ferstenberg, DO Current Issues in Management of DCIS: Radiation Oncology Consideration Fariba Asrari, MD DCIS Cases Moderator: Diane Buchbarker, MD Panelists: Angela Keleher, MD and Fariba Asrari, MD 9:45 a.m. Break/Visit Exhibits Session 2 Adjuvant Therapy: Picking the Right Treatment for Each Patient Moderator: Roisin Connolly, MD 10:00 a.m. Individualizing Adjuvant Therapy for HER2 positive Breast Cancer Cesar Santa-Maria, MD

10:20 a.m. 10:40 a.m. 11:00 a.m. 11:20 a.m. Evolving Adjuvant Endocrine Therapy Considerations: The Role of Ovarian Function Suppression and Duration of Treatment Raquel Nunes, MD Evolving Adjuvant Chemotherapy Considerations: Use of Genomic Profiles and the Role of Anthracyclines Jane Raymond, MD Individualizing Radiation Therapy Decisions for Early Stage Breast Cancer Jean Wright, MD Adjuvant Therapy Cases Moderator: Roisin Connolly, MD Panelists: Cesar Santa-Maria, MD; Raquel Nunes, MD; Jane Raymond, MD; Jean Wright, MD 11:40 a.m. Lunch Session 3 Neoadjuvant Therapy Considerations Moderator: Lisa Jacobs, MD 12:30 p.m. 1:00 p.m. 1:20 p.m. 1:40 p.m. 2:00 p.m. Individualizing Neoadjuvant Systemic Therapy: Exploring Options for Escalation and De-escalation Christie Hilton, DO Using Imaging to Assess Response to Neoadjuvant Therapy Lisa Mullen, MD Novel Local/Regional Neoadjuvant Trials Thomas Julian, MD Radiation after Neoadjuvant Therapy Mark Trombetta, MD Surgical Management after Neoadjuvant Therapy Melissa Camp, MD

2:20 p.m. Neoadjuvant Therapy Cases Moderator: Lisa Jacobs, MD Panelists: Christie Hilton, MD; Lisa Mullen, MD; Thomas Julian, MD; Mark Trombetta, MD; Melissa Camp, MD 2:40 p.m. Break/Visit Exhibits Session 4 Metastatic Disease 3:00 p.m. 3:20 p.m. Update in Palliative Radiation for Metastatic Breast Cancer Sara Alcorn, MD Exploring New Drugs, New Pathways, and New Combinations for the Treatment of Metastatic Breast Cancer Evanthia Roussos Torres, MD Session 5 Survivorship 3:40 p.m. 3:55 p.m. 4:10 p.m. 4:25 p.m. 4:40 p.m. 5:00 p.m. Integrative Care/Life Style Management for Breast Cancer Survivors Sarah Miller, DO Diet, Weight, and Exercise in Breast Cancer Survivors Jenni Sheng, MD Fertility Preservation in Breast Cancer Patients: Use of Assisted Reproductive Techniques Anthony Wakim, MD GnRH Analogs for Fertility Preservation: What Are the Data? Karen Smith, MD Cardiology Considerations During and After Breast Cancer Therapy Indu Poornima, MD Closing Remarks Thomas B. Julian, MD; Christie Hilton, DO; Karen Lisa Smith, MD; Jean L. Wright, MD

Accreditation is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit Designation Statement designates this live activity for a maximum of 7.5 AMA PRA Category 1 Credit. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit. Other Credit American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit from organizations accredited by the ACCME. American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credit from organizations accredited by the ACCME. American Academy of Physician Assistants (AAPA) accepts AMA PRA Category 1 Credit from organizations accredited by the ACCME. has approved this activity for 7.5 contact hours for non-physicians. Hotel Accommodations Overnight accommodations at the Wyndham Grand Hotel can be made by calling 412-391-4600. Please be sure to mention Breast Cancer Conference when reserving your room. The room rate is $199 + tax and the deadline to make reservations is February 19, 2019.

Refund Policies A refund of the registration fee, less a $10.00 processing fee, will be made when a written request or a telephone request followed by a written confirmation is received prior to March 15, 2019. After this date, refunds will not be made. Fees will not be refunded for failure to attend. The sponsors of this conference reserve the right to cancel or postpone any conference because of unforeseen circumstances or insufficient enrollment. In the event of such cancellation, full tuition will be refunded. Registration Information The registration fee includes the course materials, continental breakfast, lunch, and break refreshments. Fees Physicians....................................................... $90 Nurses and Other Health Care Professionals......................... $45 Fellows and Residents.......................................... No Fee Off-site Webcast Attendee........................................ $35 (limited to first 25 registrants) Deadline: March 15, 2019 (Registrations will be taken after the deadline date on a space-available basis.) To register: Please go to www.aghcme.org and select conference schedule from the left-hand side and scroll to find the conference. The preferred method of payment is by VISA, MasterCard, American Express, or Discover. Additional Information For additional information concerning the conference, please contact the Continuing Medical Education office by email at rachel.phillips@ahn.org, or by telephone at 412-359-4952.

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