SPRING SYMPOSIUM ACG/FGS ANNUAL MARCH 18 20, 2016 ATTENDEES: USE THE. NEW ACG MOBILE APP TO ACCESS FACULTY PRESENTATIONS (See PG 8) MOC

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2016 ACG/FGS ANNUAL SPRING SYMPOSIUM HYATT REGENCY COCONUT POINT, BONITA SPRINGS, FLORIDA MARCH 18 20, 2016 Course Directors: Chris E. Forsmark, MD, FACG Cynthia Levy, MD EARN CME UP TO12 CREDITS EARN MOC UP TO12 POINTS ATTENDEES: USE THE NEW ACG MOBILE APP TO ACCESS FACULTY PRESENTATIONS (See PG 8)

2016 ACG/FGS ANNUAL SPRING SYMPOSIUM JOIN COLLEAGUES FOR THE ACG/FGS ANNUAL SPRING SYMPOSIUM at the Hyatt Regency Coconut Point Resort & Spa in beautiful Bonita Springs, Florida. The program is designed to fill your mornings learning about the latest clinical updates, and your afternoons exploring the area and enjoying the many amenities the resort offers. 2

March 18 20, 2016 HYATT REGENCY COCONUT POINT BONITA SPRINGS, FLORIDA While at the Hyatt Regency Coconut Point Resort & Spa, relax poolside at the 5,000 sq. ft. Adventure Pool; and for the young at heart, take a ride down the 140 ft. corkscrew slide leading into the expansive lagoon-style pool. Or pamper yourself at the Stillwater Spa that s nestled among the beautiful greenery surrounding the resort. In addition, if golf is your game, you ll find it at the Hyatt Regency Coconut Point Resort & Spa with their world-class 18-hole golf course. Go off property and there are many more things to do and see within a short drive of the resort. Daily sessions wrap up by 1:00 pm, giving you plenty of opportunity to relax and unwind. WHO SHOULD ATTEND: Gastroenterologists GI Trainees Primary Care Physicians GI Nurses Physician Assistants Nurse Practitioners REGISTER ONLINE: GI.ORG/REGIONAL-MEETINGS 3

EDUCATIONAL AGENDA 4 Thursday THURSDAY, MARCH 17, 2016 5 PM 7 PM ON-SITE REGISTRATION WILL BE OPEN Friday FRIDAY, MARCH 18, 2016 6:30 am Registration / Continental Breakfast 7:55 am Welcome and Introductions 8:00 am Microbiome: Role in Health and Disease Lawrence J. Brandt, MD, MACG Describe the involvement of gut microbiota in maintenance of overall health. 8:30 am Prebiotics, Probiotics, Symbiotics, and Antibiotics Role in IBS William D. Chey, MD, FACG Formulate a treatment plan targeting the gut microbiota in patients with irritable bowel syndrome. 9:00 am New Approaches in the Treatment of IBD Oriana M. Damas, MD Determine appropriate and cost-effective treatment goals for IBD, utilizing new and evolving therapies.

2016 ACG/FGS ANNUAL SPRING SYMPOSIUM MARCH 18 20, 2016 HYATT REGENCY COCONUT POINT, BONITA SPRINGS, FL 9:30 am Panel Discussion / Q & A 10:00 am Break / Visit Exhibits 10:30 am Update on Pancreatic Cysts Peter V. Draganov, MD, FACG Recognize the types of pancreatic cysts and their malignancy potential. 11:00 am Advanced Endoscopic Imaging Michael B. Wallace, MD, MPH, FACG Discuss the utility of new technology such as high definition white light, NBI, and chromoendoscopy to improve management of premalignant mucosal diseases. 11:30 am Strategies to Enhance Patient Engagement James S. Leavitt, MD, FACG Create real and measureable value that will be critical for future success. Understand the value proposition from the patient's perspective and how engaging patients will enhance your value proposition to them and contribute to successful clinical and business outcomes. 12 Noon Panel Discussion / Q & A 12:30 pm Announcements 12:40 pm Adjourn 5

EDUCATIONAL AGENDA (cont.) Saturday SATURDAY, MARCH 19, 2016 7:30 am Continental Breakfast 7:55 am Introductions 8:00 am HBV: Update and Treatment Guidelines Virginia C. Clark, MD, MS Identify the appropriate therapy for patients with chronic hepatitis B infection. 8:30 am Update in HCV Treatment Kalyan R. Bhamidimarri, MD, MPH Identify the appropriate treatment choices for various HCV genotypes. 9:00 am Alcoholic Liver Disease Paul Martin, MD, FACG Define the current definitions for diagnosis of alcoholic liver disease and alcoholic hepatitis. 9:30 am Panel Discussion / Q & A 10:00 am Break / Visit Exhibits 6 10:30 am Management of PSC: Update and Guidelines Cynthia Levy, MD Apply the most recent guidelines for diagnosis of patients with PSC.

2016 ACG/FGS ANNUAL SPRING SYMPOSIUM MARCH 18 20, 2016 HYATT REGENCY COCONUT POINT, BONITA SPRINGS, FL 11:00 am Severe Acute Pancreatitis Chris E. Forsmark, MD, FACG Develop a systematic management approach to severe acute pancreatitis. 11:30 am Neuroendocrine Tumors Steven E. Rodgers, MD, PhD Improve the ability to accurately stage neuroendocrine tumors. 12 Noon Panel Discussion / Q & A 12:30 pm Announcements Sunday 12:40 pm Adjourn SUNDAY, MARCH 20, 2016 7:30 am Continental Breakfast 7:55 am Introductions 8:00 am Ischemic Colitis Lawrence J. Brandt, MD, MACG Interpret recommendations from most recent guidelines for the diagnosis of ischemic colitis. 8:30 am Colon Cancer Syndromes Daniel A. Sussman, MD, MSPH Describe the appropriate management of colon cancer syndromes as recommended in recent guidelines. 9:00 am Management of Visceral Pain William D. Chey, MD, FACG Apply appropriate strategies for the management of visceral pain, including medical and behavioral therapies. 9:30 am Panel Discussion / Q & A 10:00 am Break / Visit Exhibits 10:30 am Update on C. difficile Colitis David H. Kerman, MD Determine the most appropriate treatment plan for patients with C. difficile, including the role of surgical therapy and fecal transplantation. 11:00 am Barrett s Esophagus Ablate Everyone? Herbert C. Wolfsen, MD, FACG Utilize the most accurate endoscopic techniques to identify and characterize Barrett s esophagus. 11:30 am Managing Short Bowel Syndrome Patricia M. Byers, MD Discuss the role of intestinal transplantation in managing patients with short bowel syndrome. 12 Noon Panel Discussion / Q & A 12:30 pm Announcements 12:40 pm Adjourn ATTENDEES: USE THE NEW ACG MOBILE APP TO ACCESS FACULTY PRESENTATIONS (See PG 8) 7

PROGRAM DESCRIPTION / ACCOMMODATIONS 8 PROGRAM DESCRIPTION The field of gastroenterology continues to experience an introduction of new and novel diagnostic techniques and therapeutic options affecting numerous areas of GI disease management and patient care. This program is designed to explore those areas which the gastroenterologist often faces in clinical practice and will address management updates in a variety of gastrointestinal and hepatic areas. During the program, several broad topics will be explored, including the role of the gut microbiota, new approaches in the treatment of IBD, pancreatic cysts, advanced endoscopic imaging, hepatitis B, hepatitis C, PSC, severe acute pancreatitis, neuroendocrine tumors, ischemic colitis, colon cancer syndromes, management of visceral pain, C. difficile colitis, alcoholic liver disease, Barrett s esophagus, management of short bowel syndrome and strategies to enhance patient engagement. This program is designed for gastroenterologists, primary care physicians, nurses, physician assistants and nurse practitioners interested in the latest information on diagnostic GI and state-of the art treatment of these illnesses. ACCREDITATION/CME This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the American College of Gastroenterology and the Florida Gastroenterologic Society. The American College of Gastroenterology is accredited by the ACCME to provide continuing medical education for physicians. The American College of Gastroenterology designates this live activity for a maximum of 12 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. MOC POINTS Successful completion of this CME activity enables the participant to earn up to 12 MOC points in the American Board of Internal Medicine s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC points. REGISTRATION The registration fee includes admission to all sessions; continental breakfasts on Friday, Saturday, and Sunday; and mid-morning coffee breaks. NEW: Included with your registration is complimentary access to the course presentations via the ACG Mobile app. The app can be used to download faculty presentations onto tablets, mobile devices, and laptops with note-taking and highlighting capabilities. Take notes at the event and continue reviewing them when you get home. Presentations will also be available online in PDF format. You will have access prior to the course to download or print the slides. (NOTE: A printed syllabus will not be provided) All registrants must pay the full registration fee; one-day registration is not available. $275 ACG and FGS Members and Fellows $125 ACG Trainees/GI Fellows/Resident Members $125 ACG Allied Health Members or ACG NP/PA Members $375 Non-member Physicians/PharmD $175 Non-member NP/PA or Allied Health (RN, LPN)

2016 ACG/FGS ANNUAL SPRING SYMPOSIUM MARCH 18 20, 2016 HYATT REGENCY COCONUT POINT, BONITA SPRINGS, FL Full refund of registration fees will be given, less a $25 administrative fee, if written notice of cancellation is received by ACG by February 26, 2016. No refunds will be given after this date. Attendees may register by submitting the enclosed registration form with payment in U.S. funds to the College headquarters by fax at 301-263-9025, by mail to ACG, 6400 Goldsboro Road, Suite 200, Bethesda, MD 20817, or online at gi.org/regional-meetings. ACCOMMODATIONS Escape the hectic pace of everyday life and join us at the Hyatt Regency Coconut Point Resort & Spa in beautiful Bonita Springs, Florida, situated alongside breathtaking Estero Bay. Go off property and there are many more things to do and see within a short drive off the resort. The Hyatt Regency Coconut Point Resort & Spa is located at 5001 Coconut Road, Bonita Springs, Florida 34134. To make your reservation, please contact the Hyatt Regency Coconut Point Resort & Spa at 239-444-1234. Special meeting room rates per night are $295 single/double plus tax. The Resort Amenities Program fee, which is included in the room rate, includes: wired high speed internet access, golf bag storage, bicycle usage, local telephone calls, 800/888 telephone surcharges, incoming faxes, DVD rental, complimentary self-parking, resort trolley, beach ferry, and exercise facilities. Reservations must be made by February 24, 2016. All major credit cards are accepted. There are a limited number of rooms available at the meeting rate. Requests for reservations received after this date will be on a space available basis only. All reservations require a deposit of one night s room and tax by guest check or credit card to be charged upon reservation. Check in is 4:00 pm. Check out is 11:00 am. MORE INFORMATION For more information about the meeting, call ACG at 301-263-9000. Americans with Disabilities Act: Attendees of this ACG Regional Course who need additional reasonable accommodations or who have special needs (including dietary needs) should contact the ACG office at 301-263-9000 or by email at info@gi.org no later than February 26, 2016. 9

COURSE DIRECTORS / FACULTY 10 COURSE DIRECTORS Chris E. Forsmark, MD, FACG Professor of Medicine Chief, Division of Gastroenterology, Hepatology, and Nutrition University of Florida, Gainesville, FL Cynthia Levy, MD Associate Professor of Medicine FACULTY Lawrence J. Brandt, MD, MACG Professor of Medicine and Surgery Albert Einstein College of Medicine, Bronx, NY Kalyan R. Bhamidimarri, MD, MPH Assistant Professor of Clinical Medicine Patricia M. Byers, MD Professor of Surgery William D. Chey, MD, FACG Professor of Medicine Director, GI Physiology Lab University of Michigan, Ann Arbor, MI Virginia C. Clark, MD, MS Assistant Professor of Medicine Program Director, Gastroenterology Fellowship Program University of Florida, Gainesville, FL Oriana M. Damas, MD Assistant Professor of Medicine Peter V. Draganov, MD, FACG Professor of Medicine University of Florida College of Medicine, Gainesville, FL David H. Kerman, MD Assistant Professor of Clinical Medicine James S. Leavitt, MD, FACG GastroHealth, Miami, FL Paul Martin, MD, FACG Professor of Medicine Chief, Division of Hepatology Steven E. Rodgers, MD, PhD Associate Professor of Clinical Medicine Daniel A. Sussman, MD, MSPH Associate Professor of Clinical Medicine Michael B. Wallace, MD, MPH, FACG Professor of Medicine, Mayo Clinic, Jacksonville, FL Herbert C. Wolfsen, MD, FACG Associate Professor of Medicine Mayo Clinic, Jacksonville, FL

REGISTRATION FORM PARTICIPANT INFORMATION (Please print or type information as you would like it to appear on your name badge) NAME MUST check all that apply: MD* DO* PhD RN NP LPN PA PharmD Other: *Please enter your 10-digit NPI number above (required if physician) ADDRESS CITY STATE ZIP PHONE FAX 2016 ACG/FGS ANNUAL SPRING SYMPOSIUM MARCH 18 20, 2016 HYATT REGENCY COCONUT POINT, BONITA SPRINGS, FL PAYMENT INFORMATION REGISTRATION FEES (please check one) $275 ACG and FGS Members and Fellows $125 ACG Trainees/GI Fellows/Resident Members $125 ACG Allied Health Members $125 ACG NP/PA Members $375 Non-Member Physician/PharmD/PhD/Guest $175 Non-Member Trainees/GI Fellows/Residents $175 Non-Member NP, PA and Allied Health (e.g., RN, LPN) PAYMENT TYPE CHECK PAYABLE TO ACG IS ENCLOSED. (Check payment must be received before February 26, 2016) CREDIT CARD: MASTERCARD VISA AMEX EMAIL (required for meeting confirmation/receipt) RETURN COMPLETED REGISTRATION FORM WITH PAYMENT IN U.S. FUNDS TO ACG MAIL: American College of Gastroenterology 6400 Goldsboro Road, Suite 200 Bethesda, MD 20817 FAX: 301-263-9025 REGISTER ONLINE: gi.org/regional-meetings Full refund of registration fees will be given, less a $25 administrative fee, if written cancellation notice is received by ACG by February 26, 2016. No refunds will be given after this date. CARDHOLDER NAME CARD NUMBER EXP. DATE SIGNATURE SECURITY CODE (3 or 4 digits) TODAY S DATE

AMERICAN COLLEGE OF GASTROENTEROLOGY 6400 Goldsboro Road, Suite 200 Bethesda, MD 20817 2016 ACG/FGS ANNUAL SPRING SYMPOSIUM HYATT REGENCY COCONUT POINT, BONITA SPRINGS, FL MARCH 18 20, 2016 REGISTER TODAY! gi.org/regional-meetings ATTENDEES: USE THE NEW ACG MOBILE APP TO ACCESS FACULTY PRESENTATIONS (See PG 8)