Relieving Arthritis Knee Pain Michael J. Repine MD Boulder Medical Center Orthopedics

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Arthritis is COMMON Relieving Arthritis Michael J. Repine MD Boulder Medical Center Orthopedics 303-622-3172 More than 43 million people have some form of arthritis. It is estimated that the number of people affected by arthritis will increase to 60 million by 2020. Source: CDC This program will touch upon the following topics: Review of Knee Anatomy Discussion of Arthritis Latest Treatment Options for Knee Arthritis Expectations/Outcomes About My Practice Undergraduate at CU Boulder University of Colorado School of Medicine for medical school and residency Board certified in 2005, 2015 Fourteen years at the Boulder Medical Center In addition to the management of arthritis, I enjoy trauma, sports-related injuries, and hand

Normal Knee Bony Anatomy The Knee Joint Musculature Multiple muscles acting upon knee joint The Knee Joint Ligaments Stability Complex array of ligaments Critical for knee stability and function The Knee Joint Cartilage Cartilage is critical in understanding arthritis

The Knee Joint Cartilage Normal Cartilage Transmits applied loads across mobile surfaces Lines the ends of bones Surfaces roll or slide during motion Like the frosting on a piece of cake Like the tires on your car Healthy, normal cartilage rolls easily Smooth motion Hyaline cartilage is fluid-filled wear-resistant surface It reduces friction coefficient to 0.0025. Damaged Cartilage When the cartilage is thinned or absent, problems such as pain, instability, limited motion occur. What is ARTHRITIS? Definition: Inflammation of a joint, usually accompanied by pain, swelling, and stiffness. This mechanical wearing of the cartilage surface leads to deterioration in the joint or ARTHRITIS

What is ARTHRITIS? What is ARTHRITIS? Definition: The mechanical wearing of the cartilage surface resulting in pain and limited function. Normal Anatomy Normal Xrays Importantly, this mechanical change is accompanied by biochemical changes What is ARTHRITIS? Arthritis Anatomy Arthritic Xrays Most Common Causes of Arthritis Degenerative wear and tear Osteoarthritic traumatic Rheumatoid inflammatory Bacterial - infectious

Diagnosing Medical history Physical examination X-rays, Radiographic Studies Other tests Symptoms PAIN Weight-bearing activities While sleeping at night Located across entire knee or focally to an area Usually slow in onset Diagnosis Medical History How and when did the pain start? If the pain has occurred before, how was it treated? What activities aggravate the pain? What activities relieve the pain? Diagnosis Physical Examination Tenderness to the touch Weakness in the muscles Extent of passive and active range of motion Crepitation

Diagnosis X-ray Evaluation X-rays of an arthritic knee: narrowing of the joint space cystic changes in the bone formation of bone spurs (osteophytes) Diagnosis Additional Tests Blood tests Computerized Tomography (CT) scans Magnetic Resonance Imaging (MRI) scans Best non-surgical modality to identify focal cartilage defects Arthroscopy Small areas of traumatic arthritis, loose bodies Physical Therapy Almost always start with physical therapy Improve range of motion Improve strength Decreases pain Medications NSAIDS Decreases inflammation Decreases pain

Supplements Lots of claims NONE have passed FDA testing as proven Personal trials Cortisone injection PROS Relatively easy Excellent diagnostic tool Well-tolerated Very predictable reduction in pain Cortisone injection CONS Must be placed carefully Masks symptoms Can soften cartilage Used to buy time Viscosupplement Purify Hylauronic acid from rooster combs or bacterial growth Oil-additive to joint fluid

Viscosupplement PROS Protects remaining cartilage Improves biochemical environment of joint Reliable reduction in pain Viscosupplement CONS NONE * With appropriate patient selection Small potential for reaction with repetitive administration Stem Cell Therapy Great claims of what can be treated Promising early anecdotal reports Expensive Likely the best future option for moderate arthritis Surgical Treatment Algorithm Focal versus Global

Surgical Treatment Algorithm Decision Variables Individualized with each patient Focal or Global arthritis Age, strength, range of motion Focal cartilage damage Must catch damage early Best treated before secondary bony changes occur Pothole Focal cartilage damage Microfracture Largely treated arthroscopically

Focal cartilage damage Cartilage Transplantation Focal cartilage damage Resurfacing More advanced arthritis requires more advanced surgical options Advanced Arthritis Patient determines the appropriate time for surgical intervention Influenced by Xray Unlike hip arthritis, You CAN miss the boat for certain procedures

At this point decision is between a partial knee replacement versus a total knee replacement Partial versus Total Patient Variables Age Weight Range of motion Alignment Additional arthritis? Xrays Expectations My Philosophy: Do ONE surgery well Partial Knee Three distinct compartments

Partial Knee Makoplasty technique Partial Knee Computer assisted Preoperatively template from CT Scan Extreme precision Partial Knee Partial Knee Resurfacing

Total Knee Tri-compartmental arthritis Mal-alignment Knee contractures Patient factors Total Knee Makoplasty technique Computer Assisted Knee Makoplasty Technique: Preoperative CT scan data is synced to intraoperative data with a probe Implant positioning and surgical resection can be planned before any cuts are actually made Total Knee Computer assisted Preoperatively template from CT Scan Extreme precision

Total Knee Real time guidance Balance knee ligaments Less invasive Total Knee Game changer Total Knee Game changer Recovery Begins immediately Improvements in anesthesia/pain control also facilitate immediate mobility Start working with therapy to get out of bed WBAT

Summary You choose the time to intervene for knee replacement Have to work hard at recovery Very predictable outcome with a painless and fully functional knee joint