The Croatian viewpoint for labour analgesia and anaesthesia

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Spring Congres of the Finish Society of Anaesthesiologist (Obstetric Anaesthesia branch, SOAT) The Croatian viewpoint for labour analgesia and anaesthesia Dragica Kopic,MD, Department of Anaesthesiology and Intensive Care Unit, University Hospital Split

Split University Hospital Split University Hospital is the central health facility southern Croatian area. This institution as a regional hospital, revolves around one million Croatian citizens About 500 000 residents of the southern part of neighboring RBH, As well as around 500 000 tourists during the season. This makes the number of potential two million people.

Split University Hospital in 2012 Beds 1539 Number of employees 3325 Medical workers 2463 Medical doctors-specialists 460 Residents 123 Biochemists 15 Nurses + lab workers 1865 Support staff 862

Department of Anesthesia and Intensive Care Unit Number of employees 167 Anesthesiolgists 46 Anesthesia residents 13 Anesthesia assistances 37 Nurses 62 Number of anesthesia/per year 22516 Operating theaters 20 ICU beds 18

Regional anesthesia in Croatian Obstetrics In Croatia epidural analgesia for labour and delivery was introduced 40 years ago in Sveti Duh (Zagreb) Hospital and Petrova Clinic (Zagreb), simultaneously. At the same time, in Rijeka Clinical Center caudal block was performed for the first time. Howewer it took some 10 years or more to establish complete pain relief service in those hospitals

Regional anesthesia in Obstetrics, Split University Hospital In 1990. some effort was made in order to establish pain relief service for labour and delivery. But during the war all anesthesiologist were engaged in caring for war casualties. Needs of parturients were put on side until 2003.

Regional anesthesia in Obstetrics University Hospital Split (2003) In 2003. in the University Hospital Split, labour epidural analgesia was performed at the rate of < 0.03%. Regional anesthesia for CS was performed with rate of 4%. The introduction of regional anesthesia techniques in obstetrics wasn t easy and always welcomed.

Type of analgesia for vaginal delivery 2003 UNIVERSITY HOSPITALS (2003) HOSPITAL ZAGREB RIJEKA SPLIT TOTAL DELIVERY NUMBER 1997 2493 3283 EPIDURAL ANALGESIA 345 (17) 494 (19) 11 (<1) SPINAL ANALGESIA 0 0 0 NARCOTIC-MEPERIDINE 1012 (51) 679 (27) 727 (22) NOTHING 640 (32) 1320 (53) 2547 (77.6) (%)

Survey of Obstetrics anaesthesia Practices in Croatia in 2003 Short questionnaires were sent to Croatian anaesthesiology departments regarding analgesia and anaesthesia practices for childbirth during 2002 and 2003. 3 university hospitals and 5 city hospitals 14,133 deliveries (35% of registered Croatian birth for 2002) Results: 2003 Anaesthesia for C/S (%) Analgesia for SVD (%) Hospital GA RA None IV LEA University 61 39 58 31 11 City 93 7 63 37 <1

Epidural Analgesia in University Hospital Split LEA< 0.03% till 2004 Increased parturient request for EA Kybele Foundation sponsored additional education of two anesthesiologist Established team work between obstetricians and anesthesiologist September 2004 Establised Labor Pain relief service Childbirth education classes for parturient and family members were introduced Field of action and resposibility of every team member is defined Indication for EA is established by obstetricians Contraindication for EA is established by anesthesiologist

The First Obstetric Anesthesia Meeting Bol, Island Brač, Croatia 2005 Kybele team in capital town Kybele team on the way to Bol, the island Brač

Regional anesthesia in Obstetrics 2005 In September 2005, The First Obstetric Anesthesia Meeting was held, which was envisaged as a symposium and practical educational event. Kybele lecturers (12 anesthesiologists, an internal medicine doctor and a midwife) have been working and living for 15 days in Croatia.

Regional anesthesia in Obstetrics 2005 The two day symposium was attended by 67 anesthesiologists from Croatia and 7 from neighboring countries. Practical education was conducted in 9 hospitals where Kybele instructors worked in ORs and delivery rooms and educated local practitioners on techniques of regional anesthesia.

Delivery department in the old building

OR in the Old building

One of the ladies who had a privilege to give a birth with epidural analgesia

Epidural labour pain Relief The most impressive effect (of epidural analgesia) is to bring TRANQUILLITY and HUMANITY to delivery suite, as well as HAPPINESS and DIGNITY to a woman on one of the most important occasions in her life. Doughty, A. Epidural analgesia in labour: The past, present and future. Proc R Soc Med 71:879, 1978

Cesarean section performed in spinal anaesthesia

Regional anaesthesia techniques for labour epidural analgesia Epidural analgesia Combined Spinal Epidural (CSE) Analgesia Single Shot Spinal (SSS) analgesia

Guidelines for regional anesthesia in obstetrics Complete resuscitation equipment Performed by specialist only (resident under supervision) Obstetricians examination and consent is prerequsite Venous access is mandatory Basic monitoring of mother and fetus during the entire procedure Available personnel to perform an emergency CS Standards for postanaesthetic monitoring

Guidelines for regional anesthesia in obstetrics

Technique for labour epidural Sitting position analgesia Sterile prep and drape, any interspace between L 2 and S 1 LOR for identification of epidural space, cephaleddirected bevel Midline aproach Once the epidural space is identified, insert a multiport epidural catheter 5-6 cm If aspiration is negative, test catheter for IT or IV placement

Epidural kit

Patient postioning, prep and drape,skin infiltation

LOR technique for identification of epidural space

Choices of Local Anesthetics Drugs and Opioids for Labor Epidural Analgesia Catheter position testing Lidocaine 2 % -3-4ml Loading dose/ bolus technique 0.25% Levobupivacaine/Bupivacaine 5-10 ml Fentanyl 5 g/ml (Sufentanyl 0.5 g/ml) (condition: VAS score 3)

Labour Epidural Analgesia Continuous infusion Levobupivacaine/ Bupivacaine 0.125%; Fentanyl 1.5 g/ml- 8-15 ml/hr (condition: VAS score 3) PCEA: Levobupivacaine 0.125% + Fentanyl 1.25 g/ml basal infusion rate- 8ml/h Bolus dose 5ml/h Lock out interval 15min

Combined Spinal Epidural Analgesia Single space technique ( needle trough needle ) Spinal injectate: Levobupivacaine 2.5 mg (0.5ml of 0.5% Levob) Fentanyl 25µg (0.5ml) Start infusion: 0.1 % levobupiv. +Fent 2µg/ml PCEA: Basal infusion: 6-8 ml/h Bolus: 5 ml every 15 min Lockout: 15 min Hourly limit: 20 ml

Single shot spinal analgesia Indications : Multiparous with dilatation >6 cm Primiparous with dilatation > 8 cm Spinal needle: 27 G pencil point Spinal injectate: Levobupivacaine 2.5 mg (0.5% plain) Fentanyl 25µg

Spinal anesthesia for Cesarean section Small pencile point needle 27 G Bupivacine 0.5% (plain is only one available) 1.6-2.2ml +20 µg Fentanyl +0.3 ml of 40% Glucose Sitting position Co load of 500-1000 ml of crystalloid Left lateral tilt of 15 degrees to minimise aortocaval compression Ephedrine or Phenylefrine is available for hypotension tretament

Dosing scheme of bupivacaine according to the weight and height of the parturinet Weight (kg) Height (cm) 140 145 150 155 160 165 170 175 180 50 1.5 1.7 1.8 1.9 55 1.5 1.6 1.8 1.9 2.0 60 1.4 1.6 1.7 1.8 2.0 2.1 65 1.4 1.5 1.7 1.8 1.9 2.1 2.2 70 1.3 1.5 1.6 1.8 1.9 2.0 2.2 2.3 75 1.4 1.5 1.7 1.9 2.0 2.1 2.3 2.4 80 1.4 1.5 1.7 1.8 2.0 2.1 2.2 2.4 85 1.4 1.6 1.8 1.9 2.1 2.2 2.3 90 1.4 1.6 1.7 1.9 2.0 2.2 2.3 95 1.5 1.7 1.8 2.0 2.1 2.3 100 1.5 1.7 1.8 1.9 2.1 2.2 105 1.6 1.7 1.9 2.0 2.2 110 1.7 1.8 2.0 2.2 0.4-0.5 ml of Fentanyl is usually added to hyperbaric bupivacaine

University Hospital Rijeka (In 2001 labour epidural analgesia is in the rutine use) YEAR Delivery number Epidural analgesia Cesarean Section N (%) General Regional/ anaest. spinal 2002 2634 450 (18) 287 (10.1) 128 159 (56.4) 2003 2760 496 (18) 275 (9.9) 105 170 (63) 2004 2827 507 (18.2) 272 (9.8) 99 173 (63.2) 2005 1.1.-31.8.) 1930 386 (21) 225 (11.6) 80 145 (63.4) (%)

University Hospital Split (epidural labour analgesia started in 2003) YEAR Delivery number Epidural analgesia Cesarean Section N (%) General anaest. 2002 4006 0 530 (13.2) 530 1 Regional/ spinal 2003 3918 10 635 (16.2) 604 31 2004 4267 41 (.9) 607 (14.2) 599 18 (3) 2005 4310 154 (1.3) 627 (14.5) 544 83 (13.2) 2006 4329 194 (4.8) 615 (14.2) 474 (77) 141(23) *(%)

2010-New building of Department of Obstetrics and Gynecology

The first labour with epidural analgesia in new building

CS performed in spinal anaesthesia

Regional analgesia and anaesthesia in Croatian Obstetrics in 2011. Hospital Delivery number Labour Epidural anlgesia N (%) Cesarean Section General anaesthesia Regional/ spinal PETROVA* 4266 985 (23) 1126 (26.4) 726 400 (35.5) SVETI DUH* 3185 898 (28.2) 627 (19.6) 106 414 (66) RIJEKA* 3053 641 (21) 341 (11.4) 110 231 (68) SPLIT** 4991 198 (4) 881 (17.6) 614 267 (30.3) PULA** 1410 153 (10.8) 246 (17.4) 46 200 (76.6) ZADAR** 1679 164 (9.8) 261 (15.5) 213 48 (18.4) *hospitals with long standing LEA services, ** hospitals with short standing LEA services (after 2005)

Regional anaesthesia in Croatian Obstetrics 2012 Hospital Delivery number Vaginal delivery Labour epidural analgesia Cesarean delivery No General Regional/ spinal ZAGREB MERKUR 1540 1224 286 (23.4) 316 236 (74.7) 80 (25.3) SPLIT 4720 3764 208 (5.5) 956 (22.25) 560 (58.6) 396 (41.4) SISAK 1021 792 0 229 (22.4) 24 (10.4) 205 (89.5) OSIJEK 2513 1878 22 (1) 635 (25.3) 482 (76) 153 (24) ZADAR 1752 1474 219 (14.8) 278 (15.86) 245 (88.1) 33 (11.9) DUBROVNIK 1094 882 6 212 (19.4) 59(28) 153(72) ČAKOVEC 1077 894 4 183 (17) 130 (71) 53 (29) ŠIBENIK 665 518 24 (4.6) 147 (22.1) 110 (74.8) 37 (25)

What and where is the main cause for low rate of epidural analgesia in UHS?? shortage of anaesthesiologist in delivery department shortage of obstetricans in delivery department shortage of midwifes in delivery department

New building Number of operating theaters in the new building: 2 ORs-for elective gynecological procedures 1 OR for elective and emargency CS 1 OR for outpatient surgical procedures emergencies and epidural analgesia in delivery department Number of availabe anaesthesiologists 2 specialist +1 resident

Duties of one attending anaesthesiologist Elective CSs Emergency CSs Outpatient (ambulatory) surgery Delivery department = 4 jobs simultaneously On the two different floors In the most cases there is no availabe anaesthesiologist for epidural analgesia till 3pm. Women's needs for epidural analgesia are at the bottom of the priority list

In spite of all, my grandson and many others babies were born with epidural analgesia

How to improve labour analgesia and anaesthesia Communication Cooperation Team work etc The Best Possible Outcomes for All