Gastrointestinal Oncology

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2 nd MD ANDERSON INTERNATIONAL MEETING IN Gastrointestinal Oncology CURRENT PRACTICE AND CONTROVERSIES in the Era of Personalized Medicine e Madrid, 13 th -15 th November, 2019 SCIENTIFIC PROGRAM Meeting Directors: Registrations: www.mdanderson.es/gastrointestinaloncology @MDAnderson_ES

SCIENTIFIC COMMITTEE Gastrointestinal Oncology Multidisciplinary Unit, MD Anderson Cancer Center Madrid SCIENTIFIC COMMITEE COORDINATORS Dr. Jose María Viéitez MEDICAL ONCOLOGY Dr. Sara Encinas RADIATION ONCOLOGY Dr. Cristina Garrán DIAGNOSTIC IMAGING Dr. Raquel Saiz Dr. Juan Carlos Alonso SURGICAL ONCOLOGY Dr. Oscar Alonso Dr. Gloria Ortega PATHOLOGY Dr. Ana Teijo GASTROENTEROLOGY Dr. Mercedes García-Casas Dr. José Luis Calleja CLINICAL TRIALS Ms. Belén Bautista Wednesday, November 13 th, 2019 16:30-16:45 WELCOME AND INTRODUCTION IMMUNOTHERAPY 16:45-18:35 SYMPOSIUM: IMMUNOTHERAPY IN GASTROINTESTINAL CANCER Dr. Sara Encinas 16:45-17:05 Basis of cancer immunotherapy. Does it work in GI tumors? Michael J. Overman 17:05-17:25 Immunotherapy in gastric cancer Dr. María Alsina Vall d'hebron Instituto de Oncología, Barcelona, Spain 17:25-17:45 Immunotherapy in pancreatic cancer Dr. Robert A. Wolff 17:45-18:05 Immunotherapy in hepatocellular cancer Dr. Javier Sastre Hospital Clínico San Carlos, Madrid, Spain 18:05-18:35 Discussion

Thursday, November 14 th, 2019 COLORECTAL CANCER (non-metastatic) 08:30-10:00 MULTIDISCIPLINARY SYMPOSIUM Michael J. Overman 08:30-08:50 Radiation therapy in rectal cancer: short course vs long course Dr. Prajnan Das 08:50-09:10 Systemic therapies in colorectal cancer. New trends Dr. Cathy Eng Vanderbilt University, Nashville, USA 09:10-09:30 Mutated BRAF Dr. Elena Élez 09:30-10:00 Discussion 10:00-10:30 KEYNOTE LECTURE Presented by: Dr. Óscar Alonso 10:00-10:20 Innovation in rectal cancer surgery. TATME. Robotic surgery. Techniques and results Dr. Eloy Espín 10:20-10:30 Questions 10:30-11:00 Coffee break 11:00-11:45 DEBATE Adjuvant therapy in stage III colon cancer: are 3 months enough? Dr. Sara Encinas 11:00-11:10 Introduction and voting 11:10-11:20 Against Dr. Cathy Eng Vanderbilt University, Nashville, USA 11:20-11:30 Pro Dr. Carlos Fernández-Martos Fundación Instituto Valenciano de Oncología, Valencia, Spain 11:30-11:40 Discussion 11:40-11:45 Voting after debate 11:45-13:00 MULTIDISCIPLINARY TUMOR BOARD PANEL: Dr. Cathy Eng Vanderbilt University, Nashville, USA Surgical Oncology Dr. Eloy Espín Radiation Oncology Dr. Prajnan Das Dr. Elena Élez Diagnostic Imaging Dr. Raquel Saiz PRESENTERS: 11:45-12:10 Colorectal clinical case 1 12:10-12:35 Colorectal clinical case 2 12:35-13:00 Colorectal clinical case 3 13:00-14:10 Lunch

METASTATIC COLORECTAL CANCER 14:10-16:00 MULTIDISCIPLINARY SYMPOSIUM Dr. Óscar Alonso Dr. Ruth Vera Complejo Hospitalario de Navarra, Pamplona, Spain 14:10-14:30 Radioembolization in CRC liver metastases and HCC Dr. Nuria Rodríguez Salas Hospital Universitario La Paz, Madrid, Spain 14:30-14:50 Liver transplant for non-resectable liver metastases Dr. René Adam Hôpital Paul Brousse, Université Paris-Sud, Villejuif, France 14:50-15:10 ALLPS: indications, technique and results Dr. Ricardo Robles Hospital Universitario Virgen de la Arrixaca, Murcia, Spain 15:10-15:30 Can biology help select patients for resection of colorectal liver metastases? Dr. Jean-Nicolas Vauthey 15:30-16:00 Discussion 16:00-16:40 KEYNOTE LECTURE Presented by: Dr. Gloria Ortega 16:00-16:30 Update in the treatment of colorectal peritoneal disease. HIPEC. PIPAC Dr. François Quenet Institut de Cancer de Montpellier, France 16:30-16:40 Discussion 16:40-17:00 Coffee break 17:00-17:45 DEBATE Native Kras left colon cancer, do we know enough to consider anti-egfr as the standard 1 st line treatment? 17:00-17:10 Introduction and voting 17:10-17:20 Against Dr. Alfredo Carrato Hospital Universitario Ramón y Cajal, Madrid, Spain 17:20-17:30 Pro Dr. Ruth Vera Complejo Hospitalario de Navarra, Pamplona, Spain 17:30-17:40 Discussion 17:40-17:45 Voting after debate 17:45-18:45 MULTIDISCIPLINARY TUMOR BOARD Dr. René Adam Hôpital Paul Brousse, Université Paris-Sud, Villejuif, France PANEL: Surgical Oncology Dr. Jean-Nicolas Vauthey Surgical Oncology Dr. François Quenet Institut de Cancer de Montpellier, France Surgical Oncology Dr. Ricardo Robles Hospital Universitario Virgen de la Arrixaca, Murcia, Spain Dr. Alfredo Carrato Hospital Universitario Ramón y Cajal, Madrid, Spain Diagnostic Imaging Dr. Raquel Saiz PRESENTERS: 17:45-18:05 Metastatic disease clinical case 1 18:05-18:25 Metastatic disease clinical case 2 18:25-18:45 Metastatic disease clinical case 3

Friday, November 15 th, 2019 TRANSLATIONAL ONCOLOGY 08:30-09:40 TRANSLATIONAL ONCOLOGY SYMPOSIUM Dr. Juan Fernando García García Dr. Gema Moreno 08:30-08:50 Detection of autofluorescent cancer stem cells in colon cancer and their utility in diagnostic tool Dr. Bruno Sainz Universidad Autónoma de Madrid, Spain 08:50-09:10 Pancreas cancer subtypes: clinical relevance Dr. Francisco X. Real Centro Nacional de Investigaciones Oncológicas-CNIO, Madrid, Spain 09:10-09:40 Translational oncology clinical case Dr. Ana Teijo PANCREATIC TUMORS 09:40-11:30 MULTIDISCIPLINARY SYMPOSIUM Dr. Cristina Garrán Dr. José Manuel Ramia Hospital Universitario de Guadalajara, Spain 09:40-10:00 Borderline resectable pancreatic cancer Dr. Matthew H.G. Katz 10:00-10:20 Role of radiation therapy in pancreatic cancer Dr. Prajnan Das 10:20-10:40 Surgery and transplant in NET liver metastases Dr. Carmelo Loinaz Hospital Universitario 12 de Octubre, Madrid, Spain 10:40-11:00 Role of nuclear medicine in the treatment of metastatic NET 11:00-11:30 Discussion 11:30-12:00 Coffee break Dr. Mercedes Mitjavila Hospital U. Puerta de Hierro-Majadahonda, Madrid, Spain 12:00-12:30 KEYNOTE LECTURE Presented by: 12:00-12:20 New therapies in metastatic NET 12:20-12:30 Discussion Dr. Enrique Grande 12:30-13:15 DEBATE Is neoadjuvant therapy needed in resectable pancreatic cancer? Dr. Ana Ruiz Hospital U. Puerta de Hierro-Majadahonda, Madrid, Spain 12:30-12:40 Introduction and voting 12:40-12:50 Pro 12:50-13:00 Against 13:00-13:10 Discussion Dr. Robert A. Wolff Dr. Matthew H.G. Katz 13:10-13:15 Voting after debate

13:15-13:55 MULTIDISCIPLINARY TUMOR BOARD PANEL: Dr. Carmelo Loinaz Hospital Universitario 12 de Octubre, Madrid, Spain Dr. Robert A. Wolff Radiation Oncology Dr. Prajnan Das Surgical Oncology Dr. Matthew H.G. Katz Diagnostic Imaging Dr. Raquel Saiz PRESENTERS: 13:15-13:35 Pancreatic tumor clinical case 1 13:35-13:55 Pancreatic tumor clinical case 2 13:55-14:00 CLOSING REMARKS

Under de auspices of: * *The opinions expressed by the organizers do not necessarily reflect the position of SEPD Organized by: Venue: MD Anderson Foundation Spain Auditorium Arturo Soria, 270 28033 Madrid, Spain Accreditation: Applications for CME credits will be forwarded to the Spanish Accreditation Council for Continuing Medical Education. With the collaboration of the Educational Committee of the MD Anderson Cancer Center Madrid. Language: The official language of the meeting is English. Meeting Secretariat: Monasterios de Suso y Yuso 34 28049 Madrid (+34) 91 372 02 03 e-mail: gastrointestinaloncology@doctaforum.com www.mdanderson.es/gastrointestinaloncology