Oil & Gas Manuscript: Supplemental Materials

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Oil & Gas Manuscript: Supplemental Materials Overview of WRF Modeling Version.5 of the WRF model, Advanced Research WRF (ARW) core (Skamarock et al., 2008) was used for generating hourly 2011 meteorology. WRF was initialized with the 12km North American Model (12NAM) analysis product provided by National Climatic Data Center (NCDC). When the 12NAM data was not available, the 40 km Eta Data Assimilation System (EDAS) analysis (ds609.2) from the National Center for Atmospheric Research (NCAR) was used to fill these gaps. Physics options include Kain-Fritsch cumulus parameterization utilizing the moisture-advection trigger, Pleim-Xiu land surface model, Asymmetric Convective Model version 2 planetary boundary layer scheme, RRTMG longwave and shortwave radiation schemes, and Morrison double moment microphysics. The ipxwrf program was used to initialize deep soil moisture at the start of the run using a 10-day spinup period (Gilliam and Pleim, 2010). Landuse and land cover data were based on the 2011 National Land Cover Database (NLCD 2011). Sea surface temperatures were ingested from the Group for High Resolution Sea Surface Temperatures (GHRSST) (Stammer et al., 200) 1 km data product. Analysis nudging for moisture, winds, and temperature were applied above the boundary layer only. References Gilliam, R.C., Pleim, J.E., 2010. Performance assessment of new land surface and planetary boundary layer physics in the WRF-ARW. Journal of Applied Meteorology and Climatology 49, 760-774. Skamarock, W.C., Klemp, J.B., Dudhia, J., Gill, D.O., Barker, D.M., Duda, M.G., Huang, X., Wang, W., Powers, J.G., 2008. A description of the Advanced Reserch WRF version. NCAR Technical Note NCAR/TN-475+STR. Stammer, D., Wentz, F., Gentemann, C., 200. Validation of microwave sea surface temperature measurements for climate purposes. Journal of Climate 16, 7-87.

P Table S-1: Epidemiological Study Parameters Used to Quantify PMR2.5R-Attributable Risks Endpoint Premature Mortality Cohort study, allcause Study Krewski et al. (2009) Lepeule et al. (2012) Study Population >29 years >24 years Risk Estimate (95P PPercent Confidence Interval)P A RR = 1.06 (1.04 1.06) per 10 µg/mp RR = 1.14 (1.07 1.22) per 10 µg/mp Time series, all-cause Zanobetti and Schwartz (2009) All ages Chronic Illness Nonfatal heart Peters et al. (2001) attacks Hospital & Emergency Department Admissions Adults (>18 years) RR = 1.0098 (1.0075 1.022) OR = 1.62 (1.1 2.4) per 20 µg/mp Respiratory Cardiovascular Babin et al. (2007) ICD 49 (asthma) Moolgavkar (2000) ICD 490 496 (COPD) Zanobetti and Schwartz (2006) ICD 470-519 (All Respiratory) Pooled estimate from random effects meta-analysis estimate Pooled using equal weights: Zanobetti and Schwartz (2009) ICD 90-459 (all cardiovascular) Peng et al. (2009) ICD 426-427; 428; 40-48; 410-414; 429; 440-449 (Cardio-, cerebro- and peripheral vacsular disease) Peng et al. (2008) ICD 426-427; 428; 40-48; 410-414; 429; 440-449 (Cardio-, cerebro- and peripheral vacsular disease) <19 β=0.002 (0.0047) 18 64 years 1.02 (1.01 1.0) per 6 µg/mp >64 years β=0.00207 (0.00446) All ages RR = 1.02 (1.00 1.04) >64 years β=0.00189 (0.00028) >64 years >64 years β=0.00068 (0.000214) β=0.00071 (0.0001)

Asthma-related ER visits Other Health Endpoints Bell et al. (2008) ICD 426-427; 428; 40-48; 410-414; 429; 440-449 (Cardio-, cerebro- and peripheral vacsular disease) Moolgavkar (2000) ICD 90 429 (all cardiovascular) Mar et al. (2004) Slaughter et al. (200) >64 years 20 64 years All Ages Acute bronchitis Dockery et al. (1996) 8 12 years Upper respiratory symptoms Lower respiratory symptoms Asthma exacerbations Pope et al. (1991) Schwartz and Neas (2000) Ostro et al. (2001) (cough, wheeze and shortness of breath) Mar et al. (2004) (cough, shortness of breath) Asthmatics, 9 11 years 7 14 years 6 18 years RR=1.04 (t statistic: 4.1) per 10 µg/mp RR = 1.04 (1.01 1.07) per 7 µg/mp RR = 1.0 (0.98 1.09) per 10 µg/mp OR = 1.50 (0.91 2.47) per 14.9 µg/mp 1.00 (1 1.006) per 10 µg/mp OR = 1.11 (1.58 1.58) per 15 µg/mp RR = 1.04 (1.01 1.07) per 7 µg/mp RR = 1.0 (0.98 1.09) per 10 µg/mp Work loss days Ostro (1987) 18 65 years β=0.0046 (0.0006) Minor Restricted Activity Days (MRADs) Ostro and Rothschild (1989) 18 65 years β=0.00220 (0.000658) A Where available, relative risk (RR) and odds ratios (OR) are reported from each epidemiological study. Otherwise, beta coefficients and standard errors are reported from each study. Beta coefficients were derived from each RR or OR using the following equation: (LN(RR or OR))/unit change in pollution.

Table S-2: Epidemiological Study Parameters Used to Quantify OzoneR-Attributable Risks Endpoint Premature Mortality Study Study Population Risk Estimate th (95P PPercentile Confidence Interval)P Smith et al. (2009) All Ages β = 0.0002 (0.00008) Time Series Zanobetti & Schwartz (2008) All Ages β = 0.00051 (0.00012) Hospital & Emergency Department Admissions Respiratory Asthma ED visits Asthma Exacerbation School loss days Acute Respiratory Symptoms Katsouyanni et al. (2009) >65 β = 0.00064 (0.00040) Glad et al. (2012) All Ages β = 0.0006 (0.00117) Ito et al. (2007) >64 years β = 0.00521 (0.00091) Mar and Koenig (2010) All ages β = 0.01044 (0.0046) (0-17 yr olds) β = 0.00770 (0.00284) (18-99 yr olds) Peel et al. (2005) All ages β = 0.00087 (0.0005) Sarnat et al. (201) All ages β = 0.00111 (0.00028) Wilson et al. (2005) All ages RR = 1.022 (0.996 1.049) Mortimer et al. (2002) 6-18 β = 0.00929 (0.0087) Schildecrout et al. (2006) 6-18 β = 0.00222 (0.00282) Chen et al. (2000) 5-17 β = 0.01576 (0.004985) Gilliland et al. (2001) 5-17 β = 0.007824 (0.004445) Ostro and Rothschild 18-65 β = 0.002596 (0.000776) A Procedure for projecting death rates to future years The BenMAP-CE program contains age- and cause-stratified death rates for each county in the contiguous U.S. through the year 2060 in 5-year increments. To estimate these rates, we calculated annual adjustment factors, based on a series of Census Bureau projected national mortality rates (for all- cause mortality), to adjust the age- and county-specific mortality rates calculated using an average of 2012-2014 data from the CDC-WONDER database as a baseline (Table S-1). We used the following procedure:

1. For each age group, we obtained the series of projected national mortality rates from 201 to 2050 (see the 201 rate in Table S-1 below) based on Census Bureau projected life tables. 2. We then calculated, separately for each age group, the ratio of Census Bureau national mortality rate in year Y (Y = 2014, 2015,..., 2060) to the 201 rate. These ratios are shown for selected years in Table S-2.. Finally, to estimate mortality rates in year Y (Y = 2015, 2020,..., 2060) that are both agegroup-specific and county-specific, we multiplied the county- and age-group-specific mortality rates for 2012-2014 by the appropriate ratio calculated in the previous step. For example, to estimate the projected mortality rate in 2015 among ages 18-24 in Wayne County, MI, we multiplied the mortality rate for ages 18-24 in Wayne County in 2012-2014 by the ratio of Census Bureau projected national mortality rate in 2015 for ages 18-24 to Census Bureau national mortality rate in 201 for ages 18-24. Table S-: All-Cause Mortality Rate (per 100 people per year) by Source, Year and Age Group Source & Year 18-24 25-4 5-44 45-54 55-64 65-74 75-84 85+ Calculated CDC 2012-2014 0.078 0.107 0.17 0.405 0.862 1.797 4.628 1.580 Census Bureau 201 1 0.088 0.102 0.18 0.87 0.90 2.292 5.409 1.091 Table S-4: Ratio of Future Year All-Cause Mortality Rate to 201 Estimated All-Cause Mortality Rate by Age Group Year 18-24 25-4 5-44 45-54 55-64 65-74 75-84 85+ 2015 0.96 1.02 0.96 0.96 1.01 1.02 1.0 1.00 2020 0.98 1.04 0.97 0.98 1.02 1.0 1.0 1.00 2025 0.74 0.80 0.75 0.77 0.85 0.91 0.9 0.97 1 For a detailed description of the model, the assumptions, and the data used to create Census Bureau projections, see the working paper, Methodology and Assumptions for the 2012 National Projections, which is available on http://www.census.gov/population/projections/files/methodology/methodstatement12.pdf

P P Healthcare Table S-5: Baseline and Prevalence Rates for Included Morbidity Endpoints Endpoint Parameter Hospitalizations Daily hospitalization rate Asthma ER Visits Nonfatal Myocardial Infarction (heart attacks) Daily asthma ER visit rate Daily nonfatal myocardial infarction incidence rate per person, 18+ Value Age-, region-, and causespecific rate Age- and regionspecific visit rate Age-, region-, state-, and county-specific rate Rates a SourceP Agency for Healthcare Research and Quality (2007) Agency for Healthcare Research and Quality (2007) 2007 AHRQ data files; adjusted by 0.9 for probability of surviving after 28 days (Rosamond 1999) Asthma Exacerbations Acute Bronchitis Lower Respiratory Symptoms Upper Respiratory Symptoms Work Loss Days Minor Restricted- Activity Days Incidence daily wheeze daily cough daily dyspnea 0.17 0.145 0.074 Prevalence among asthmatic children 0.0780 Annual bronchitis incidence rate, children Daily lower respiratory symptom incidence d among childrenp Daily upper respiratory symptom incidence among asthmatic children Daily WLD incidence rate per person (18 65) Aged 18 24 Aged 25 44 Aged 45 64 Daily MRAD incidence rate per person 0.04 Ostro et al. (2001) American Lung Association (2010) American Lung Association (2002) Table 11 0.0012 Schwartz (1994b, Table 2) 0.419 Pope et al. (1991, Table 2) 0.00540 0.00678 0.00492 0.0217 US Bureau of the Census (2001) Ostro and Rothschild (1989) a Cost and Utilization Program (HCUP) database contains individual level, state and regionallevel hospital and emergency department discharges for a variety of ICD codes.

b P P See ftp://ftp.cdc.gov/pub/health_statistics/nchs/datasets/nhds/. c P P See ftp://ftp.cdc.gov/pub/health_statistics/nchs/datasets/nhamcs/. d P P Lower respiratory symptoms are defined as two or more of the following: cough, chest pain, phlegm, and wheeze.

1 2 Table S-6: PM 2.5 and Ozone Related Morbidity Outcomes Attributable to the Oil and Gas Sector in 2025 Incidence (95% Endpoint and Pollutant confidence interval) A Premature Mortality PM 2.5 -Related Premature Death, Ages 0-1,000 99 (670 1,00) (Krewski et al. 2009) PM 2.5 -Related Premature Death, Ages 25-2,00 99 (1,100,400) (Lepeule et al. 2012) Ozone-Related Premature Death, Ages 0-50 99 (260 800) (Smith et al. 2008) Ozone-Related Premature Death, Ages 0-970 99 (520 1,400) (Zanobetti & Schwartz 2009) Respiratory Hospital Admissions, Ages 0-99 1,100 (PM 2.5 & O ) (-280 2,00) Cardiovascular Hospital Admissions, Ages 240 18-99 (110 440) Acute Bronchitis, Ages 8-12 1,00 (-00 2,900) Respiratory Emergency Room Visits, Ages 0-,600 99 (110 11,000) (PM 2.5 & O ) Asthma Exacerbation, Ages 6-18 1,100,000 (PM 2.5 & O ) (-900,000 2,600,000) Work Loss Days, Ages 18-64 110,000 (94,000 10,000) Acute Respiratory Symptoms, Ages 18-64,000,000 (PM 2.5 & O ) (1,500,000 4,400,000) Upper Respiratory Symptoms, Ages 9-11 2,000 (4,00 4,000) Lower Respiratory Symptoms, Ages 7-14 16,000 (6,00 27,000) Acute Myocardial Infarction, Ages 18-99 980 (240 1,700) School Loss Days, Ages 5-17 770,000 (O ) (270,000 1,700,000) A The confidence intervals for some endpoints were quantified by sampling from a distribution that crosses the null; thus, some lower

confidence intervals are negative. Rather than setting these to zero, we report them here as calculated. 4

5 6 7 Table S-7: Value of PM 2.5 and Ozone Related Mortality and Morbidity Outcomes Attributable to the Oil and Gas Sector in 2025 (Millions of 2015$) Incidence (95% confidence Endpoint and Pollutant interval) A Premature Mortality $1,000 (Sum of Krewski et al. 2009 & Smith et al. 2009) ($1,200 $7,000) Premature Mortality $28,000 (Sum of Lepeule et al. 2012 & Zanobett & Schwartz 2008) ($2,500 $80,000) Respiratory Hospital Admissions, Ages 0-99 $ (PM 2.5 & O ) ($-9 $71) Cardiovascular Hospital Admissions, Ages 18-99 $9 ($4 $17) Acute Bronchitis, Ages 8-12 $1 ($0 $2) Respiratory Emergency Room Visits, Ages 0-99 $ (PM 2.5 & O ) ($0 $9) Asthma Exacerbation, Ages 6-18 $61 (PM 2.5 & O ) ($-52 $180) Work Loss Days, Ages 18-64 $17 ($15 $20) Acute Respiratory Symptoms, Ages 18-64 $200 (PM 2.5 & O ) ($81 $60) Upper Respiratory Symptoms, Ages 9-11 $1 ($0 $2) Lower Respiratory Symptoms, Ages 7-14 $0.1 ($0.001 $1) Acute Myocardial Infarction, Ages 18-99 $120 ($19 $00) School Loss Days, Ages 5-17 $74 (O ) ($26 $160) A The confidence intervals for some endpoints were quantified by sampling from a distribution that crosses the null; thus, some lower confidence intervals are negative. Rather than setting these to zero, we report them here as calculated.

8 9 Figure S-1. Percent of Total Deaths Attributable to Annual Mean PM2.5 and Summer Season Daily 8-Hour Maximum Annual Mean PM2.5 Summer Season Average Daily 8-Hour Maximum Ozone 10 Ozone From the Oil and Gas Sector in 2025