Results that require action

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Following is a list of Allina Health Laboratory Results That Require Action (formerly Critical Values). Results That Require Action describes a lab test result that may indicate a lifethreatening situation. Any test falling within this range will be called to the outreach client immediately. CHEMISTRY Test name Age/sex Low High ALT 254 <18 yrs > 500 IU/L Ammonia 27 > 100 µmol/l Bilirubin, total 46 <18 yrs > 12.0 mg/dl Calcium 56 < 6.0 mg/dl > 13.0 mg/dl Calcium, ionized 8141 < 0.80 mmol/l > 1.55 mmol/l Carboxyhemoglobin 59 > 20% CK/CPK (outpatient only) 80 > 1500 IU/L CO2 (bicarbonate) 73 < 10 mmol/l > 40 mmol/l Creatinine 82 < 5 yrs > 1.5 mg/dl 5 10 yrs > 2.0 mg/dl 10 15 yrs > 3.0 mg/dl Adult > 7.0 mg/dl Glucose 0-4 hrs < 30 mg/dl <18 yrs < 40 mg/dl > 300 mg/dl 18 yrs < 40 mg/dl > 400 mg/dl Glucose, CSF < 40 mg/dl > 250 mg/dl HCO3, arterial/venous 1329 < 15 mmol/l > 40 mmol/l HCO3, capillary Base excess, umbilical cord -16 > 40 mmol/l HIV rapid assay Reactive Ketone/acetone or betahyroxybutyrate (blood) >2.5 mmol/l Lactic acid/lactate 12616 12603 Venous > 2.2 mmol/l Arterial >1.6 mmol/l Magnesium 175 < 1.2 mg/dl > 5.9 mg/dl Phosphorous 205 < 1.0 mg/dl > 10.0 mg/dl ph, arterial, venous, capillary < 7.2 > 7.6 pco2 < 20 mmhg > 70 mmhg po2 < 40 mmhg 10/2018 Page 1 of 5

CHEMISTRY cont. Test Name Age/sex Low High Potassium 211 <1 wk < 2.8 mmol/l > 6.0 mmol/l >1 wk < 2.8 mmol/l > 6.0 mmol/l Sodium 233 <10 yrs < 128 mmol/l > 160 mmol/l Adult < 120 mmol/l > 160 mmol/l Troponin I 5045 outpatient only > 0.034 ng/ml BLOOD BANK Positive antibody screen compatible blood is not available. Emergency issuance of blood crossmatch is subsequently positive or incomplete evaluation of positive antibody screen, incomplete antibody workup or antigen type of donor units not complete. COAGULATION Test Name Age/sex Low High APTT 490 0 28 days > 60 seconds APTT (Outpatient) 490 > 60 seconds Factor VII <15% Factor X Chromogenic 5767 <15% Fibrinogen 101 <100 mg% Heparin level 2283 > 1.0 units/ml Heparin antibodies Positive, indeterminate INR 487 0 28 days > 1.3 > 6.0 LMW Heparin 2281 > 1.5 units /ml 10/2018 Page 2 of 5

HEMATOLOGY Test Name Low High Blasts Any seen w/ no previous Ehrlichia Any seen Hemoglobin <7.0 gm/dl >20 gm/dl Hemoglobin (newborn*) <13.5 gm/dl >24 gm/dl Kleihauer-Betke Positive Platelet count <20,000 /mm 3 >1 million Platelet count (newborn*) <50,000 /mm 3 >1 million White blood cell count <2.0 x 10 3 /mm 3 >50.0 x 10 3 /mm 3 White blood cell count (newborn*) <5.0 x 10 3 /mm 3 >35.0 x 10 3 /mm 3 White blood cell count, CSF >5 x 10 3 /mm 3 * Newborn defined as 0-28 days 10/2018 Page 3 of 5

MICROBIOLOGY Result that Require Action call list Positive gram stains on: Amniotic, pleural, pericardial, synovial, ascitic, bile, and joint fluids Blood, bone marrow CSF Organs (kidney, liver, etc.) Surgical eye specimens Tissues from sterile sites such as bone, brain, gallbladder, heart, joint, liver, etc. Test results: Clostridium difficile toxin positive and invalid - inpatients (metro and regional hospitals) Cryptococcal antigen positive Enterovirus PCR - CSF positive, invalid Group B Strep PCR positive, invalid - Labor and Delivery patients only Legionella Urine Antigen positive Shiga toxin positive Streptococcus pneumoniae antigen positive Positive cultures: Amniotic, ascitic, bile, joint, pericardial, pleural, and synovial fluids Blood and bone marrow CSF Organs (kidney, liver, etc.) Tissues from sterile sites such as bone, joint, brain, etc. Cryptococcus neoformans from any source Group B beta Streptococcus, any source, from newborns and labor & delivery patients only E. coli 0157:H7 and Shiga toxin positive Vibrio cholerae Zygomycete from sinus, eye or nose Eye cultures Bacillus species Pseudomonas aeruginosa Streptococcus pneumoniae Any isolate from surgical eye specimens (cornea, vitreous fluid, etc.) Blood parasites (Ehrlichia, Anaplasma etc.) Dialysis water culture out-of-range results Non-Critical Result call list Bordetella pertussis - DNA Detected Clostridium difficile toxin - positive or invalid Influenza Antigen - positive Influenza A/B/H1N1 PCR - positive RSV - positive Histoplasma, Coccidioides, Blastomyces, Paracoccidioides Acid fast bacilli - smear, culture*, DNA probe results*, identification*, and susceptibilities *First results only on patients with multiple concurrent positive cultures, unless different. Outreach clinic patients: MRSA Outreach hospitals inpatients (first patient isolate, each hospitalization): MRSA, VRE, ESBL positive, carbapenemase positive, KPC positive 10/2018 Page 4 of 5

TOXICOLOGY Test Name Low High Acetaminophen 920 >100 μg/ml Carbamazepine 952 > 15.0 μg/ml Digoxin 92 > 2.5 ng/ml Gentamicin, peak 826 > 12.0 μg/ml Gentamicin, random 832 > 12.0 μg/ml Gentamicin, trough 827 > 1.5 μg/ml Lamotrigine 452 > 40.0 μg/ml Lithium 169 > 1.5 meq/l Methotrexate (24hrs. post dose) 939 > 50 μmol/l Methotrexate (48hrs. post dose) 939 > 10 μmol/l Phenobarbital 207 > 50 μg/ml Phenytoin, free 1993 > 3.0 μg/ml Phenytoin, total 91 > 30 μg/ml Salicylate 228 > 35 mg/dl Tobramycin, peak 849 > 12.0 μg/ml Tobramycin, random 833 > 12.0 μg/ml Tobramycin, trough 829 > 2.0 μg/ml Valproic acid, free 6539 > 40 μg/ml Valproic acid, total 949 > 150 μg/ml Vancomycin, peak 964 > 60 μg/ml Vancomycin, trough 963 > 25 μg/ml 10/2018 Page 5 of 5