SEVENTH ANNUAL NEUROSCIENCE, BEHAVIOR AND HEALTH RESEARCH FORUM Image: James Bishop The University of Vermont Dudley H Davis Center Grand Maple Ballroom January 20-21, 2017 Sponsored by: University of Vermont Neuroscience, Behavior and Health Initiative Vermont Chapter of the Society for Neuroscience
Howard Eichenbaum, PhD Boston University Center for Memory and Brain The hippocampus is essential to episodic memory, which is characterized by our ability to recall the spatial and temporal organization of events that constitute a specific past experience. An understanding of how the hippocampus supports episodic memory would benefit by using an animal model to identify neural coding mechanisms for the spatial and temporal organization of memories within the hippocampus. With regard to spatial organization, I will describe a recent study using Representational Similarity Analysis on neural ensembles showing that the hippocampus creates a highly organized, hierarchical network representation of features of events and the places and contexts in which they occurred. With regard to temporal organization, I will present evidence that the hippocampus is critical for memory of order of events in unique experiences in animals, as it is in humans. Furthermore, I will describe recent evidence that hippocampal "time cells" (as contrasted with the famous hippocampal "place cells") encode specific moments in the course of temporally extended experiences, and time cell ensembles encode specific memories and predict memory success. These findings support an emerging view that the hippocampus serves episodic memory by creating a scaffold for the organization of events within their spatial and temporal context.
NBH RESEARCH FORUM SCHEDULE OF EVENTS Friday, January 20 Grand Maple Ballroom 4:00 pm Hors d oeuvres 4:30 pm Welcome and Introduction: John Green, PhD, President, Vermont Chapter of the Society for Neuroscience 4:35 pm Keynote Lecture: Howard Eichenbaum, PhD, Director of the Center for Memory and Brain, Boston University. The Hippocampus: Memory in space and time. 5:35 pm Reception Saturday, January 21 Grand Maple Ballroom 8:00 am Registration and light breakfast and Poster setup 8:30-8:45 am Introductory Remarks: Mark Bouton, PhD, Director, University of Vermont Neuroscience, Behavior and Health Research Initiative Platform Session I (Chairs: Megan Shipman and Sydney Trask) 8:45-9:00 Olivia Miles, Department of Psychological Science, UVM Pituitary adenylate cyclase-activating peptide in the bed nucleus of the stria terminalis mediates stress-induced reinstatement of cocaine seeking in rats 9:00-9:15 Scott Schepers, Department of Psychological Science, UVM Extending the Concept of Context: Introceptive Context and Mechanisms of Relapse 9:15-9:30 Eric Thrailkill, PhD, Department of Psychological Science, UVM The next response, but not the reinforcer, is the goal of behavior in a chain
9:30-9:45 Bradley King, Department of Psychological Science, UVM The Effects of Prior Stress on Anxiety-like Responding to Intra- BNST Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) in Male and Female Rats 9:45-10:00 Jonah Meyerhoff, Department of Psychological Science, UVM Randomized trial of cognitive-behavioral therapy vs. light therapy seasonal affective disorder: Acute and followup outcome 10:10-10:40 Coffee Break Platform Session II (Chairs: Willie Curry and Matt McCabe) 10:45-11:00 Sarah Emerson, Department of Biology, UVM Investigating the Roles of PlexinA1 and PlexinA2 Receptors During Early Eye Development in Zebrafish 11:00-11:15 Riley St. Clair, Department of Biology, UVM Characterizing PlexinA Phosphorylation in Vertebrate Development 11:15-11:30 Ashley Waldron, Department of Biology, UVM Elucidation of Histidyl-tRNA Synthetase s Role in Zebrafish Auditory and Visual System Development 11:30-11:45 Philip Spechler, Department of Psychiatry, UVM Predicting Cannabis Use in Adolescent Males and Females from Biobehavioral Data 11:45-12:00 Scott Mackey, PhD, Department of Psychiatry Parahippocampal cortex thickness partially mediates the effects on anti-social behavior Lunch and Posters 12:00-2:00 Lunch 12:30-1:15 Poster Session I (Odd Numbers) 1:15-2:00 Poster Session II (Even Numbers)
Platform Session III (Chairs: Nick D Alberto and Greg Johnson) 2:00-2:15 Dawei Li, PhD, Department of Microbiology and Molecular Genetics, UVM Genetics of Familial Chiari I Malformation 2:15-2:30 Thomas Longden, PhD, Department of Pharmacology, UVM Brain capillaries act as a sensory web to translate neural activity into blood flow 2:30-2:45 David Bucci, PhD, Department of Psychological and Brain Science, Dartmouth College Recalling old memories: A surprising connection 3:00 Closing Remarks and Awards