Perioperative Management Of Extra-Ventricular Drains (EVD)

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Perioperative Management Of Extra-Ventricular Drains (EVD) Dr. Vijay Tarnal MBBS, FRCA Clinical Assistant Professor Division of Neuroanesthesiology Division of Head & Neck Anesthesiology Michigan Medicine

Disclosures None

Outline To understand the common indications & complications with extra-ventricular drain (EVD) placement Pre-operative assessment of patients presenting with EVD To suggest management of patients with EVD in the perioperative setting including monitoring and CSF drainage

Introduction Temporary devices placed to facilitate external CSF drainage and to monitor ICP Between 1988-2010 around 500,000 ventriculostomies placed 1 Majority in SAH, ICH or Obstructive Hydrocephalus 1 Encountered in OR setting by clinicians with limited experience Mismanagement can be catastrophic 1 Rosenbaum et al; J Clin Neurosci. 2014

Rosebaum et al; J Clin Neuroscience 2014

Rosebaum et al; J Clin Neuroscience 2014

History of EVD Placement 4 eras of progress 1 : Development of technique (1850-1908) Technological Advancements (1927-1950) Expansion of Indications (1960-1995) Accuracy, Training, Infection control (1995- Present ) 1 Srinivasan et al; J Neurosurg 2014

1 Srinivasan et al; J Neurosurg 2014

EVD Materials 1 Srinivasan et al; J Neurosurg 2014

ICP Monitoring Freeman, W.D. (2015). Neurocritical Care, 1299-323.

Outline To understand the common indications & complications with extra-ventricular drain (EVD) placement Pre-operative assessment of patients presenting for or with EVD To suggest management of patients with EVD in the perioperative setting including monitoring and CSF drainage

EVD Placement Indications

Indications for Placement of EVD 1. Acute Symptomatic Hydrocephalus Aneurysmal SAH ICH and IVH with decreased level of consciousness Acute ischemic cerebellar stroke in concurrence with decompressive craniectomy 1 Lele et al; J Neurosurg Anesthesiol 2017

Indications for Placement of EVD 2. ICP monitoring in TBI TBI with post resuscitation GCS of 3-8 and abnormal CT Severe TBI with a normal CT scan if >2 of features present (age>40, motor posturing or SBP<90) Management of Intracranial Hypertension after TBI 1 Lele et al; J Neurosurg Anesthesiol 2017

Indications for Placement of EVD 3. Malfunctioning or infected V-P Shunts 4. Facilitation of intraoperative brain relaxation 5. Targeted Therapeutic Interventions rtpa in patients with IVH and SAH? Treatment of vasospasm after SAH Antibiotics in management of CNS infections 1 Lele et al; J Neurosurg Anesthesiol 2017

Indications for placement of EVD

Site for EVD Placement Placed either electively in OR/IR or emergently at bedside 1,2 Frontal horn of right lateral ventricle- Preferred Destination Non-Dominant side for speech & language for most patients 1 Foreman et al; Clin Neurol Neurosurg. 2015 2 Kakarla et al; Neurosurgery 2008

101mm 28mm mean intracranial catheter length was 60 mm Abdoh et al; Acta Neurochir 2012

Complications Associated with EVD Placement 1,2,3 1. Hemorrhage Intracerebral hemorrhage, tract hematoma or tract hemorrhages (0-41%) 2. Infection (0-28% EVD) 3. Malposition 4. Occlusion and malfunction 1 Lele et al; J Neurosurg Anesthesiol 2017 2 Miller C: J Neurosurg. 2017 3 Niiumara et al; BMJ Case Rep. 2015

Complications Associated with EVD Placement 1,2,3 5. Over Drainage of CSF Subdural or epidural hematoma Re-bleed from a ruptured cerebral aneurysm Intracranial hypotension Cerebellar tonsillar herniation Paradoxical herniation Pneumocephalus 1 Lele et al; J Neurosurg Anesthesiol 2017 2 Miller C: J Neurosurg. 2017 3 Niiumara et al; BMJ Case Rep. 2015

Complications Associated with EVD Placement 1,2,3 6. Iatrogenic vascular injury (arteriovenous fistula, cerebral pseudo aneurysm) 7. Fracture of catheters, with retained fragment of catheters 8. Inadvertent injections of drugs 1 Lele et al; J Neurosurg Anesthesiol 2017 2 Miller C: J Neurosurg. 2017 3 Niiumara et al; BMJ Case Rep. 2015

Complications with EVD Placement

EVD System

EVD System

EVD System

EVD System

EVD Setup

EVD Setup

EVD Setup

Do not connect EVD system to a high pressure system such as pressure bag used for arterial or central venous catheter

Why Do We Need Guidelines?

51% of transports resulted in secondary insults Commonest were Arterial Hypertension & Intracranial Hypertension

Outline To understand the common indications & complications with extra-ventricular drain (EVD) placement Pre-operative assessment of patients presenting for or with EVD To suggest management of patients with EVD in the perioperative setting including monitoring and CSF drainage

Pre-Operative Evaluation Inspection of EVD System Understanding Drain Dynamics ICP Waveforms Results of Clamp Trial

Understanding Drain Dynamics CSF drainage under controlled settings CSF drain volume goals <10-20ml/hr Setting of EVD depends on indication for its placement Aneurysmal SAH (typical EVD settings) 1,2 Pre Repair. : +20cm H 2 O Post Repair : +10cm H 2 O 1 Sakowitz et al; Neurosurg 2006 2 Chung et al; Neurocrit Care 2017

ICP Waveforms Lele et al; J Neurosurg Anesthesiol 2017

Clamping Trials Tolerance to any period of clamping depends on: 1. Indication for EVD placement 2. ICP trends 3. Dependency on external CSF diversion At Risk Patients: External CSF diversion dependency Elevated ICP

11.8% of patients with post-iht ICP>20 18.5% of patients with escalation of ICP category Risk Factors Pre-IHT ICP>20, Therapeutic Procedures.

SNACC Guidelines Summary 1 Thorough Pre-Op evaluation Inspection of EVD system ICP values, trends and other multimodal monitoring data Drain Dynamics Clamping Trials Standard pre-operative handoff between NICU and Anesthesia providers 1 Lele et al; J Neurosurg Anesthesiol 2017

Outline To understand the common indications & complications with extra-ventricular drain (EVD) placement Pre-operative assessment of patients presenting for or with EVD To suggest management of patients with EVD in the perioperative setting including monitoring and CSF drainage

Intra-Hospital Transport (IHT) of Patients with EVD

Intra-Hospital Transport (IHT) of Patients with EVD At risk for secondary insult from intracranial complications Change in patient position may lead to CSF over drainage Rebleeding of Aneurysm Subdural Hemorrhage Paradoxical Brain Herniation

SNACC Guidelines Summary 1 1 Lele et al; J Neurosurg Anesthesiol 2017

Intraoperative Management of EVD

Intraoperative Management of EVD 1 Rosner et al; JNS 1986 2 Birch et al: Neurocrit Care 2006 3 Wilkinson et al; Neurosurgery 1986

Management of EVD in Special Scenarios 1 Visual aids and labeling Accidentally disconnected EVD tubing should be clamped immediately All distal parts of device replaced with a new sterile tubing (Not the EVD catheter) Routine flushing of catheter should not be performed Notify neurosurgery team immediately if there is an accidental injection via EVD Lele et al; JNA 2017

Checklists Lele et al; JNA 2017

Educational Resources

Summary Common indications, contraindications and patient preparation for extraventricular drain (EVD) placement Pre-operative assessment & IHT of patients presenting for or with EVD Management of patients with EVD in the perioperative setting including monitoring and CSF drainage