HIGH LEVEL - Science

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Learning Outcomes

HIGH LEVEL - Science Describe the structure and function of the back and spine (8a) Outline the functional anatomy and physiology of the spinal cord and peripheral nerves (8a) Describe the anatomical relationship of the spinal cord and peripheral nerve roots to the vertebral column (8a) Describe the physiology of nerve conduction (8a) Explain the difference between upper and lower motor neurone lesions (8a,b) Explain the pathological mechanisms responsible for the development of back-pain (8a)

HIGH LEVEL - Science Describe the features of medically significant causes of back pain (red flag symptoms and signs) including metastatic disease their investigation and management (8b-f,16a,b) Outline the physiology of bone health (8a) Describe the epidemiology of back pain and sickness related absence from work (9a-f) Apply knowledge about the social aspects of chronic illness to understanding patients experiences of back pain, and to clinical practices of information, support and referral (10a-d)

HIGH LEVEL - Practical Perform an examination of the spine (13c,14a,b) Perform a neurological examination of the upper and lower limbs (13c,14a,b)

HIGH LEVEL - Professional Describe the role of palliative care teams in supporting patients (22a,b) Describe the legal framework of work and ill health and processes for sickness and disability certification (20g)

LO The Case Explain the underlying mechanisms of low back pain using background knowledge of relevant anatomy Know the incidence of low back pain in primary care and the initial management (e.g.nice guidance) Know the epidemiology of low back pain Know the following conditions: non-specific / mechanical low back pain, degenerative disc disease, facet joint arthrosis, spondylolysis, spondylolisthesis, inflammatory back pain, disc prolapse, spinal stenosis, cauda equina syndrome

LO The Case Describe the red flags which may suggest more serious spinal pathology Describe the yellow flags which may limit recovery and rehabilitation Explain the social and economical burden due to sickness from work related to back pain Explain the legal framework of work and ill health and processes for sickness and disability certification Apply knowledge about the social aspects of chronic illness to understanding patients experiences of back pain, and to clinical practices of information, support and referral

LO Anatomy Session Know the macroscopic and microscopic anatomy of the bones, ligaments and muscles around the spine, the intervertebral disc, the spinal cord, meninges and nerves Demonstrate the main spinal cord motor and sensory tracts and the deficits that result as a consequence to injury Explain the different spinal cord syndromes anterior, posterior, central and Brown-Sequard Explain the difference between upper and lower motor neuron lesions with clinical examples Be familiar with normal radiological imaging of the spine X-rays, CT and MRI Demonstrate the anatomical landmarks and principles for performing epidural and spinal injection / catheter insertion

LO Nerve Plenary Describe the physiology of normal nerve conduction at a cellular level including the maintenance of a resting and action potentials via sodium and potassium gated channels Describe transmission of an electrical signal along a nerve axon and the role of the myelin sheath Describe the release of neurotransmitters at pre-synaptic junctions and subsequent generation of a post-synaptic action potential Describe the afferent and efferent pathways involved in the detection of a peripheral stimulus and the resulting motor response Describe the response of a nerve to injury in terms of neural regeneration, comparing and contrasting the peripheral and central nervous systems. Demonstrate understanding of nerve physiology and synapses with specific example of mechanism of action of local anaesthetic and other agents e.g. depolarising muscle relaxants

LO Bone Plenary Know the structure and function of bone and articular cartilage Explain the role of osteoblasts and osteoclasts in normal bone remodelling Know the relationship between calcium, vitamin D and parathyroid hormone in normal bone remodelling Describe the bones response to injury and the normal healing process for a fracture Describe the factors that prevent normal fracture healing Understand the concept of osteoporosis as a state of reduced bone mineral density and the resultant increased risk of fracture List protective factors and risk factors for the development of osteoporosis Name at least two medications used in osteoporosis for fracture prevention Describe the clinical consequences of vitamin D insufficiency (rickets and osteomalacia)

LO Spinal Pathology 1 Be familiar with the epidemiology and main causes of spinal cord injury Be familiar with the presenting features of spinal cord injury including spinal shock, neurogenic shock and autonomic dysfunction Explain the initial physiological consequences of spinal cord injury on the cardiovascular and respiratory systems Explain the concept of complete and incomplete spinal cord injury Explain the initial management and investigation of patients with spinal cord injury Explain the different spinal cord syndromes anterior, posterior, central and Brown-Sequard Explain the presenting features of cauda equina syndrome Identify the main causes of cauda equina syndrome Recognise cauda equina syndrome as a surgical emergency and understand the initial steps in its investigation and management Recognise the serious causes of back pain in a child

LO Spinal Pathology 2 Be familiar with the epidemiology of spinal metastases and metastatic spinal cord compression Identify key clinical features that would raise suspicion of metastatic spinal disease List the more common malignancies which metastasize to bone Explain the ways in which spinal metastases can cause spinal cord compression Recognise metastatic spinal cord compression as a medical / surgical emergency and understand the initial steps in its investigation and management Recognise the difficulty in the management of some cases of metastatic spinal cord compression and be aware of sources of support (palliative care / oncology / Macmillan / support groups etc.) List the presenting features and risk factors for spinal infections Explain the ways in which spinal infections can cause spinal cord compression Recognise spinal infection as a serious condition and understand the initial steps in its investigation and management Recognise epidural abscess as a surgical emergency List the more common infective agents that can cause spinal infections (including tuberculosis)

LO History Examination Be able to conduct an appropriate history from a patient with a spinal complaint / condition Describe and determine the nature of the pain in terms of Site, Onset, Character, Radiation, Associations, Time course, Exacerbating / relieving factors and Severity (SOCRATES) Describe and determine any associated features such as arm / leg pain, weakness, numbness, bladder / bowel involvement Be able to screen for any red flag features Be able to screen for any yellow flag features

LO History Examination Assess risk factors for the complaint / condition Determine the medications / treatments which have been utlilised Outline a full employment history and its impact on the clinical problem Determine the functional limitations which have resulted as a consequence of the pain Outline a full social history including smoking history and sports activities Make an enquiry as to the emotional consequences of the spinal complaint / condition Ascertain and address the ideas, concerns and expectations of a patient with a spinal complaint

LO History Examination Be able to conduct an appropriate physical examination on a patient Perform a physical inspection of the spine (assess for normal thoracic kyphosis and lumbar lordosis, presence of any spinal deformities, scoliosis, skin changes) Palpate any region of interest for tenderness Palpate vertebral spinous processes for tenderness and paraspinal muscles for muscle spasm Assess cervical and thoracolumbar spine movements actively and passively flexion / extension / lateral bending / left and right rotation

LO History Examination Perform Schobers test measure the lumbar spine flexion Perform Adams forward bending test to assess for any fixed spinal deformity Assess straight leg raising (Lasègue ssign)

LO History Examination Perform a neurological examination of the upper and lower limbs Assess gait and Rombergs sign Inspection of the limbs Assess muscle tone Assess power / strength (MRC Medical Research Council grading) according to the myotomes described by the American Spinal Injury Association (ASIA) Assess deep tendon reflexes hyper and hyporeflexia Biceps, brachioradialis, triceps, knee and ankle Assess for clonus Assess plantar responses Perform Hoffmans test Perform a full sensory dermatomal examination as described by the American Spinal Injury Association (ASIA) Coordination Assess for saddle anaesthesia and anal sphincter tone

LO Palliative Care Discuss how psychosocial and spiritual issues may impact on patients and their families Recognize the importance of patient-centred rather than doctor-centred care Define terminal illness and palliative care Describe the holistic nature of palliative care Summarize the services provided by a specialist palliative care unit Appreciate the multidisciplinary nature of palliative care Summarize how specialist palliative care links into primary care

Community Have you completed the workbook for this Case? Discuss adaptation to major life changes, such as bereavement; comparing and contrasting the abnormal adjustments that might occur in these situations Determine the extent to which patients want to be involved in decision-making about their care and treatment