Fiera di Vicenza Convention Center Vicenza - Italy

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Regione Veneto - ULSS 6 Department of Nephrology, Dialysis and Renal Transplantation International Renal Research Institute Vicenza - IRRIV San Bortolo Hospital - Vicenza - Italy th Fiera di Vicenza Convention Center Vicenza - Italy

JUNE 7, Tuesday - NO ECM (Italian Credits) Room Palladio 14.00-15.15 Industry - Sponsored satellite Symposium SESSION - AKI BIOMARKERS: The New Frontier Chairmen: J. Kellum - M. Plebani 15.30 Expanding the spectrum of AKI diagnosis C. Ronco 15.35 The Emerging Role of Biomarkers in Acute Kidney Injury J. Kellum 15.50 Integrating biomarker application into clinical routine A. Zarbock 16.05 Clinical Uses of Biomarkers in AKI Risk Assessment and Patient Management L. Forni 16.20 AKI diagnosis in China X. Ding 16.35 Discussion 17.00-18.15 Industry - Sponsored satellite Symposium 14.00-15.15 Satellite JOINED SESSION ITALIAN SOCIETY OF NEPHROLOGY AND IRRIV SIN - IRRIV Fellow Day Chairmen: A. Santoro - C. Ronco 14.00 Introduction A. Santoro 14.15 Oral presentation of selected posters 17.00-18.15 Industry - Sponsored satellite Symposium 4 OPENING CEREMONY Room Palladio 18.30 AKI & CRRT today C. Ronco 18.45 International Vicenza Award for Critical Care Nephrology 19.00 Fifteen years of ADQI: Achievements and results J. Kellum 19.30 Welcome Reception 1

JUNE 8, Wednesday - Room Palladio SESSION 1 - AKI 3W: Where, When, Why Chairmen: R. Bellomo - R.L. Mehta 8.30 Global Health Alert: update on the 0 by 25 initiative R.L. Mehta 8.50 Epidemiology of acute kidney injury in critically ill patients E. Hoste 9.10 AKI on non-renal, non ICU wards - care and outcomes M. Haase 9.30 AKI Incidence and Outcomes in Sepsis J.L. Vincent 9.50 Incidence and Outcomes in Cancer Patients M. Rosner 10.10 Discussion 10.30 Coffee Break and Visit to the Exhibition / Poster Area SESSION 2 - AKI NEW ECONOMY Chairmen: M. Rosner - J.L. Vincent 10.50 The economic impact of AKI S. Bagshaw 11.10 Economic models in AKI (The case for contrast media) C. Ronco 11.30 AKI in the era of big data (reports from ADQI) S. Bagshaw 11.50 EMR and sniffers in AKI diagnosis K. Kashani 12.10 Quality Improvement in Acute Kidney Injury: What is Quality in AKI? M. Rosner 12.30 Discussion 12.50 Lunch and Visit to the Exhibition / Poster Area 13.15-14.15 Industry - Sponsored satellite Lunch Symposium 5 SESSION 3 - RRT in AKI Chairmen: A. Tolwani - S. Bagshaw 14.30 Patient selection criteria and indications for RRT in AKI R.L. Mehta 14.50 Timing of RRT in AKI S. Bagshaw 15.10 Modality of RRT in AKI J. Cerda 15.30 Anticoagulation in RRT in AKI M. Joannidis 15.50 Antibiotics Dosages Adaptation During RRT P. Honoré 16.10 Discussion 16.30 Coffee Break and Visit to the Exhibition / Poster Area SESSION 4 - MOST Chairmen: A. Shaw - J. Cerda 16.50 Continuous ultrafiltration in heart failure: current issues and future directions. M.R. Costanzo 17.10 Extracorporeal carbon dioxide removal? F. Ferrari 17.30 Artificial extracorporeal Liver Support : current and future perspectives. G. Auzinger 17.50 CRRT and ECMO circuit: how to do it and when? A. Shaw 18.20 Discussion 18.40 Adjourn 2

JUNE 8, Wednesday - / Scamozzi NO ECM (Italian Credits) WORKSHOP 1 - CRRT Management Group Chairmen: F. Ferrari - Z. Ricci - S. Romagnoli 9.30 The importance of Multidisciplinary Team I. Baldwin 9.50 Nomenclature in CRRT: Basic Principles M. Neri 10.10 Improving Delivery of Continuous Renal Replacement Therapy F. Garzotto 10.30 CRRT Technical Complications F. Barbarigo - M. Mettifogo 10.50 Hands on session S. De Rosa (coordinator) 11.40 Discussion Room Scamozzi WORKSHOP 2 - Ultrasound in Critical Care Nephrology Chairman: M. Meola 10.30 Theoretical outline preliminary to practice M. Meola 10.50 Clinical case: Uremic pleuropericarditis M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.00 Clinical case: Chronic heart failure M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.10 Clinical case: Parenchymal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.20 Clinical case: Prerenal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.30 Hands on ultrasound in critical care nephrology M. Meola 12.30 Discussion WORKSHOP 1 - CRRT Management Group Chairmen: F. Ferrari - Z. Ricci - S. Romagnoli 14.00 The importance of Multidisciplinary Team I. Baldwin 14.20 Nomenclature in CRRT: Basic Principles M. Neri 14.40 Improving Delivery of Continuous Renal Replacement Therapy F. Garzotto 15.00 CRRT Technical Complications F. Barbarigo - M. Mettifogo 15.20 Hands on session S. De Rosa (coordinator) 16.10 Discussion Room Scamozzi WORKSHOP 2 - Ultrasound in Critical Care Nephrology Chairman: M. Meola 14.00 Theoretical outline preliminary to practice M. Meola 14.20 Clinical case: Uremic pleuropericarditis M. Meola - I. Petrucci - F. Nalesso - S. Samoni 14.30 Clinical case: Chronic heart failure M. Meola - I. Petrucci - F. Nalesso - S. Samoni 14.40 Clinical case: Parenchymal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 14.50 Clinical case: Prerenal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 15.00 Hands on ultrasound in critical care nephrology M. Meola 16.00 Discussion 3

JUNE 9, Thursday - Room Palladio SESSION 5 - AKI BIOMARKERS & Diagnosis Chairmen: S. Goldstein - L.S. Chawla 8.20 AKI: from clinical to molecular diagnosis C. Ronco 8.40 What have we learned from biomarkers? J. Kellum 9.00 Acute Kidney Stress (AKS) - A concept to accelerate early detection of AKI N. Katz 9.20 Kidney Stress test (Glomerular and tubular) L.S. Chawla 9.40 IRRIV test S. Samoni 10.00 Discussion 10.20 Coffee Break and Visit to the Exhibition / Poster Area SESSION 6 - AKI: FROM PATHOPHYSIOLOGY TO PROGRESSION Chairmen: L.S. Chawla - M. Ostermann 10.40 Pathophysiology of AKI in sepsis R. Bellomo 11.00 Interaction between systemic inflammation and renal tubular epithelial cells V. Cantaluppi 11.20 The spectrum of Acute Kidney Disease (update from ADQI) J. Kellum 11.40 Adaptive and maladaptive repair after AKI R. Bellomo 12.00 The course of recovery after AKI: is it modifiable? R.L. Mehta 12.20 Persistent versus resolved AKI L.S. Chawla 12.40 Discussion 13.00 Lunch and Visit to the Exhibition / Poster Area 13.15-14.15 Industry - Sponsored satellite Lunch Symposium 6 SESSION 7 - AKI, SEPSIS & BLOOD PURIFICATION Chairmen: P. Angeli - L.G. Forni 14.30 CRRT in AKI and Sepsis A. Tolwani 14.50 CRRT in sepsis and multisystem organ failure N. Gibney 15.10 CRRT in infants and Children S. Goldstein 15.30 Genetic and Phenotypic Patterns and Blood Purification G. Villa 15.50 Sepsis and Blood Purification: Sorbent Therapy and Endotoxin Removal C. Ronco 16.10 Discussion 16.30 Coffee Break and Visit to the Exhibition / Poster Area SESSION 8 - ORGAN CROSSTALK AND INTERACTION WITH EXTRACORPOREAL THERAPIES Chairmen: N. Gibney - R.L. Mehta 16.50 Brain and Kidney L.G. Forni 17.10 Lung and Kidney F. Husain-Syed 17.30 GI tract and Kidney and the importance of the microbiota L. Gesualdo 17.50 Liver and kidney P. Angeli 18.10 Heart and Kidney C. Ronco 18.30 Discussion 18.40 Adjourn 4

JUNE 9, Thursday - / Scamozzi NO ECM (Italian Credits) WORKSHOP 1 - CRRT Management Group Chairmen: F. Ferrari - Z. Ricci - S. Romagnoli 9.30 The importance of Multidisciplinary Team I. Baldwin 9.50 Nomenclature in CRRT: Basic Principles M. Neri 10.10 Improving Delivery of Continuous Renal Replacement Therapy F. Garzotto 10.30 CRRT Technical Complications F. Barbarigo - M. Mettifogo 10.50 Hands on session S. De Rosa (coordinator) 11.40 Discussion Room Scamozzi WORKSHOP 2 - Ultrasound in Critical Care Nephrology Chairman: M. Meola 10.30 Theoretical outline preliminary to practice M. Meola 10.50 Clinical case: Uremic pleuropericarditis M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.00 Clinical case: Chronic heart failure M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.10 Clinical case: Parenchymal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.20 Clinical case: Prerenal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 11.30 Hands on ultrasound in critical care nephrology M. Meola 12.30 Discussion WORKSHOP 1 - CRRT Management Group Chairmen: F. Ferrari - Z. Ricci - S. Romagnoli 14.00 The importance of Multidisciplinary Team I. Baldwin 14.20 Nomenclature in CRRT: Basic Principles M. Neri 14.40 Improving Delivery of Continuous Renal Replacement Therapy F. Garzotto 15.00 CRRT Technical Compli F. Barbarigo - M. Mettifogo 15.20 Hands on session S. De Rosa (coordinator) 16.10 Discussion 5 Room Scamozzi WORKSHOP 2 - Ultrasound in Critical Care Nephrology Chairman: M. Meola 14.00 Theoretical outline preliminary to practice M. Meola 14.20 Clinical case: Uremic pleuropericarditis M. Meola - I. Petrucci - F. Nalesso - S. Samoni 14.30 Clinical case: Chronic heart failure M. Meola - I. Petrucci - F. Nalesso - S. Samoni 14.40 Clinical case: Parenchymal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 14.50 Clinical case: Prerenal AKI M. Meola - I. Petrucci - F. Nalesso - S. Samoni 15.00 Hands on ultrasound in critical care nephrology M. Meola 16.00 Discussion

JUNE 9, Thursday - NO ECM (Italian Credits) 16.30-18.20 SESSION 8B - BIOETHICAL ROUNDTABLE Chairman: R. Bellomo Panel participants: L.S. Chawla - J. Kellum - C. Ronco - J.L. Vincent - N. Zamperetti 18.40 Adjourn JUNE 10, Friday - Room Palladio INTERACTIVE CASE PRESENTATION 8.20 Critical Care Nephrology cases. Discussing with the expert R. Bellomo SESSION 9 - FLUID MANAGEMENT Chairmen: S. Di Somma - S. Goldstein 9.20 Results from the DoReMiFa study C. Ronco 9.40 Role of Bioimpedance in Fluid Assessment in ER and ICU S. Di Somma 10.00 Pharmacological management of FO and monitoring B. Molitoris 10.20 Indications and management of FO with extracorporeal therapies M. Ostermann 10.40 FO and outcomes R. Murugan 11.00 Discussion 11.10 Coffee Break and Visit to the Exhibition / Poster Area SESSION 10 - NEW TECHNOLOGIES, Hot Issues and trials Chairmen: B. Molitoris - A. Tolwani 11.30 Real Time GFR B. Molitoris 11.50 Transdermal real time GFR measurements R. Solomon 12.10 New Membranes (functionalized) C. Ronco 12.30 Personalized versus protocolized therapy J.L. Vincent 12.50 End points in clinical trials L.S. Chawla 13.10 Discussion 13.30 Lunch and Farewell 6

Secretariat New Progress Service S.r.l. National Provider n 1257 Vicenza - ITALY Contacts Mrs Anna Saccardo & Mrs Marta Scabardi phone / fax +39 0444 753949 mobile +39 340 1607312 email info@irriv.com International Renal Research Institute Vicenza - IRRIV w w w. i r r i v. c o m