DISCLOSURE FNFX ORIF OR ARTHROPLASTY? 11/21/2016 FEMORAL NECK FRACTURES: ORIF OR ARTHROPLASTY? ROYALTIES DEPUY, BIOMET

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FEMORAL NECK FRACTURES: ORIF OR ARTHROPLASTY? GEORGE HAIDUKEWYCH, MD ORLANDO, FLORIDA DISCLOSURE ROYALTIES DEPUY, BIOMET CONSULTING DEPUY, SYNTHES, BIOMET, RESPONSIVE ORTHOPEDICS STOCK OWNERSHIP ORTHOPEDIATRICS NUMBERS INCREASING LIFE CHANGING INJURIES CONTROVERSIAL FNFX ORIF OR ARTHROPLASTY? COST TO SOCIETY 1

FEMORAL NECK FRACTURES OUTCOME RELATED TO: FRACTURE DISPLACEMENT AGE QUALITY OF REDUCTION FRACTURE PATTERN?? TIMING FNFX ORIF OR ARTHROPLASTY? NON-DISPLACED FRACTURES ARE TREATED THE SAME REGARDLESS OF PATIENT AGE ORIF SCREWS CAREFUL ATTENTION TO SCREW PLACEMENT IS IMPORTANT FNFX ORIF OR ARTHROPLASTY? PERIPHERAL CALCAR SUPPORT ABOVE LESSER TROCHANTER 2

3

FNFX ORIF OR ARTHROPLASTY? DISPLACED FRACTURES REMAIN CONTROVERSIAL PHYSIOLOGIC AGE COGNITION?? STATUS OF THE HIP JOINT MEDICAL PROBLEMS CALLAGHAN ET AL JBJSBr 2012 FNFX ORIF OR ARTHROPLASTY? IN GENERAL, UNDER AGE 60, I PREFER ORIF THE BEST FEMORAL HEAD IS YOUR OWN ANATOMIC REDUCTION IS VERY IMPORTANT ORIF YOUNG FEMORAL NECKS URGENT TREATMENT TRY CLOSED REDUCTION, IF NOT PERFECT, OPEN IT FIX BASED ON FRACTURE VERTICALITY 4

CHOOSE FIXATION DEVICE BASED ON SHEAR ANGLE LIPORACE ET AL JBJS Am 2008 5

OPEN REDUCTION TECHNIQUE 54 FEMALE 6

CAPSULOTOMY?? LENGTH-STABLE INTERNAL FIXATION? ORIF YOUNG FEMORAL NECKS URGENT ANATOMIC SHEAR ANGLE CAPSULOTOMY 85% WILL KEEP THEIR HIPS 10 YEARS, EVEN THOUGH ABOUT 25% WILL GET AVN HAIDUKEWYCH ET AL JBJS Am 2004 7

DISPLACED FEMORAL NECK FRACTURES IN THE ELDERLY FEMORAL NECK FRACTURE Prosthetic Replacement Unipolar? Bipolar? THA? Cement? Press fit? DISPLACED FNFX IN THE ELDERLY THE FAILURE RATE OF ORIF IN THIS SETTING REMAINS AT ABOUT 40% UNCHANGED FOR THE LAST SEVENTY YEARS.. BHANDARI ET AL JBJS 2004. KEATING ET AL JBJS 2006 8

48 OR 84? FEMORAL NECK FX FAILURES CEMENTED HEMIARTHROPLASTY FOR DISPLACED FRACTURES IN OLDER PATIENTS HAS 10 YEAR SURVIVORSHIP FREE OF REVISION OF 94% Haidukewych et al CORR 2002 9

FEMORAL NECK FX FAILURES OLDER PATIENT RIGHT OPERATION?? ORIF DISPLACED FEMORAL NECK FX REOPERATION RATES CONSISTENTLY AT AROUND 40% OVER THE LAST SEVEN DECADES Bhandari et al JBJS 2004 FEMORAL NECK FX FAILURES SUMMARY: THE REOPERATION RATE FOR ORIF OF DISPLACED FEMORAL NECK FRACTURES IN ELDERLY PATIENTS IS 10 TIMES HIGHER!!! THAN FOR ARTHROPLASTY 10

DISPLACED FNFX ELDERLY ARTHROPLASTY OFFERS LOWER REOPERATION RATE BETTER FUNCTION LOWER COST SAME MORTALITY SAME MEDICAL RISK BIPOLAR vs. UNIPOLAR NO DIFFERENCE AT MID TERM FOLLOW UP BIPOLAR WITH LONGER F-U ACETABULAR EROSION POLY WEAR COST BIPOLAR 10 YEAR SURVIVORSHIP 94% 11

WHAT ABOUT THA?? HOT TOPIC BETTER FUNCTION THAN BIPOLAR NO INCREASE IN COMPLICATIONS OR MORTALITY DISLOCATION IS AN ISSUE (OLD LITERATURE?) DATA THA BETTER: KEATING ET AL JBJS 2006 BLOMFELDT ET AL JBJSBr 2007 SKODENBURG ET AL JBJS Br 2011 HEDBECK ET AL JBJSBr 2011 GJERTSEN ET AL ACTA ORTHOP 2007 HEETVELD ET AL JOT 2009 ORIF vs arthroplasty for displaced femoral neck fractures ORIF - reduced operative time, operative blood loss, need for transfusion, and risk of deep wound infection Arthroplasty - lower revision rate No differences found in hospital LOS, mortality, residual pain, or regaining mobility Cochrane review 2002 12

ORIF vs Hemi vs THR RCT 278 patients > 65 years old SHS vs uncemented AM vs cemented semiconstarined THR One year mortality similar for 3 groups Revision rate: ORIF 33%, hemi 13%, THR 4% Dislocation rate: hemi 11% and THR 12.5% THR had least pain and best mobility in short and long term f/u Hemiarthroplasty had worst functional results Skinner et al, Injury 1989 ORIF vs Hemi vs THR RCT 290 patients > 65 years old SHS vs uncemented AM vs cemented THR Mortality rate similar for 3 groups Revision rate: ORIF 33%, hemi 24%, THR 6.8% Dislocation rate: hemi 13% and THR 20% Harris hip scores: ORIF 62, hemi 55, THR 80 THR had least pain and best mobility in short and long term f/u Ravikumar and Marsh, Injury 2000 ORIF vs Bipolar vs THR Prospective randomized multicenter Displaced FN fxs, pts > 60 years 298 pts- ORIF (118); cemented bipolar (111); cemented THR (69) ORIF fixation failure (AVN,NU) - 37% ORIF 8x more likely to require revision surgery than bipolar and 5x than THR Functional outcome highest for THR Keating et al, JBJS 2006 13

Current consensus THR Bigger procedure, peri-op complications Improved function Over all hemiarthroplasties Baker, JBJS(A) 06 Gebhard, Amstutz, ClinOrthop 92 Even after successful ORIF Tidermark, Törnkvist, JBJS(B) 03 Excellent survivorship: 94% at 10 yrs Lee, Berry JBJS(A) 98 Cost effective Iorio, Healy, Clin Orthop 01 Cost effectiveness* at 2 years Repair (Screws) $24,600 Bipolar $22,000 Unipolar $21,600 Cemented THR $20,700 *Hospital +rehab +(revision surgery probability x cost) Internal Fixation Compared with Arthroplasty for Displaced Fractures of the Femoral Neck: A Meta-Analysis 140 studies examined (14 randomized trials) After ORIF 9.7% AVN 20% AVN 18.5% nonunion 30% Nonunion Reoperation 10-48% after ORIF 20-36% 0-24% after hemiarthroplasty Death w/in 1 year 20% after ORIF 30% 23% after arthroplasty Bhandari, et.al. JBJS 85-A, 2003. 14

Intracapsular Hip Fractures: Results of Management Adopting a Treatment Protocol 166 patients Managed by physiologic score to choose between ORIF and arthroplasty in displaced fracture, elderly age group (65-85 yrs). CM Robinson et al., CORR 302, 1994 "Physiologic Score" Mobility (5 points) Accommodation (5 pts) Osteoporosis (Singh Index, 6 points) Cognition (10 questions, 5 points) Medical (5 points) Management Protocol <65 or non-displaced ORIF 65-85 Physiologic Score > 20 < 20 > 85 Prosthesis CM Robinson et al., CORR 302, 1994 15

Results ORIF done in 42% of patients aged 65-85. 2-yr mortality 14% AVN 5% Nonunion 2% Dislocation 3% Reoperation 5% CM Robinson et al., CORR 302, 1994 Internal fixation versus hemiarthroplasty versus total hip arthroplasty for displaced subcapital fractures of the femur 13 year results of a prospective randomized study 271 elderly patients randomized into 3 groups: Internal fixation Hemiarthroplasty Cemented total hip arthroplasty Ravikumar and Marsh, Injury 31: 793, 2000 Long-term (13 year) Results ORIF 33% revised (25% in 1st year) Hemiarthroplasty 25% revised Dislocation rate 13% THA Overall survival 93% Dislocation rate 20%, only 6% recurrent Ravikumar and Marsh, Injury 31: 793, 2000 16

Long-term (13 year) Results ORIF and hemiarthroplasty patients deteriorated over time. Mortality remained equal over time. THA group: least pain and best function. Ravikumar and Marsh, Injury 31: 793, 2000 Changing trends in the RX of FN fxs: a review of the ABOS database 19,541 FN fxs Rxd by 4450 ABOS candidates, 1999-2011 Use of THA increased (0.7% in 1999, 7.7% in 2011, p < 0.001) Proportion of pts < age 65 managed with THA increased from 1.4% to 13.1% (p < 0.001) Candidates with subspecialty of "adult recon" had increasing use of THA (4.3% from 1999 to 2002, 21.1% from 2009 to 2011, p < 0.001) while "trauma" subspecialty candidates had decreasing use of ORIF (40.9% from 1999 to 2002, 32.9% from 2009 to 2011, p = 0.012) Miller et al JBJS 2014 CEMENTED OR UNCEMENTED? GOOD RESULTS WITH BOTH TECHNIQUES, SLIGHT TREND FAVORING CEMENTED STEMS DEANGELIS ET AL JOT 2012 JAMESON ET AL JBJSBr 2012 STAFFORD ET AL ANN R COLL SURG 2012 TAYLOR ET AL JBJS Am 2012 17

DISLOCATION THA FOR FNFX WHY? NOT STIFF GET MOTION EARLY FALLS COMPLIANCE DEMENTIA? ROLE OF DUAL MOBILITY? REASONABLE CHOICE TO MINIMIZE RISK OF DISLOCATION ADAM ET AL ORTHOP TRAUM SURG 2012 TARASEVICIUS ET AL BMC 2010 18

THA FOR FNFX 66 FEMALE WHAT ABOUT THA?? STEM FIXATION STRATEGY ON BONE QUALITY BIGGEST HEAD YOU CAN. ROLE OF DUAL MOBILITY? CONSIDER SURGICAL APPROACHES THAT MINIMIZE DISLOCATION RISK PATIENT EDUCATION 19

SUMMARY THE GOAL IS TO PROVIDE GOOD FUNCTION WHILE MINIMIZING COMPLICATIONS AND REOPERATIONS A SIMPLE ALGORITHM CAN BE HELPFUL MY ALGORITHM NON-DISPLACED FRACTURES, ANY AGE ORIF WITH THREE SCREWS SPREAD OUT, CALCAR SUPPORT START ABOVE LESSER TROCHANTER MY ALGORITHM DISPLACED FRACTURES UNDER AGE 60 URGENT ORIF FIXATION DEVICE BASED ON VERTICALITY (BEWARE HIGH SHEAR ANGLES!) ANATOMIC REDUCTION CAPSULOTOMY? 20

MY ALGORITHM DISPLACED FRACTURES AGE 60-80 TOTAL HIP ARTHROPLASTY ANTEROLATERAL APPROACH MODULAR CUP WITH SCREWS BIGGEST HEAD POSSIBLE DUAL MOBILITY? STEM FIXATION BASED ON BONE QUALITY MY ALGORITHM DISPLACED FRACTURE OVER AGE 80 CEMENTED HEMIARTHROPLASTY ANTEROLATERAL APPROACH CLEAN AND DRY CANAL WELL ANTIBIOTICS IN CEMENT? THANK YOU 21