Restore biomolecular balance to enjoy natural vitality and live your life to the fullest

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www.bio-r.ch

Restore biomolecular balance to enjoy natural vitality and live your life to the fullest Eduardo Greghi CEO & Chairman Antoinette Sarasin Gianduzzo Director of Biomolecular Restoration, Nutrition and Lifestyle 02

Balance The human body, with all of its interconnected systems, is the most advanced structure in the known universe - a perfect combination of biochemical structuring and biomechanical engineering. When we come in to this world, our bodies are finely tuned and in perfect balance. 03

Imbalance As we then grow, life begins to take its toll. In today s fast-paced society, maintaining a healthy lifestyle can be difficult. More often than not, we don t get enough of the essential vitamins, amino and fatty acids, trace elements and minerals our bodies need to keep up with the busy lives we lead. This, in turn, has an effect on our complex biochemistry, creating deficiencies and imbalances, which can lead us to feel mentally and physically unwell. Thankfully, through Biomolecular Restoration, it is possible to restore your natural biochemistry. 04

Swiss Biomolecular Restoration (Bio-R ) Bio-R is an innovative and highly personalised medical approach to improve physical and emotional well-being. It works by detecting and correcting imbalances in our individual biochemistry and neurochemistry. It significantly improves physical health, vitality and emotional well-being. Our Bio-R Expert Team has carefully developed orthomolecular medicine and integrative medicine to create unique s that help your body and brain function as smooth as Swiss clockwork. Much like a clock, our body is a finely tuned mechanism that functions due to biochemical factors that influence many aspects of our physical and mental make-up. If any of the chemical components become disrupted, the mechanism can no longer function at an optimal level. 05

Restore your balance IMBALANCE RECOVERY PROCESS BALANCE 01 02 03 04 05 Our Bio-R diagnostics and analysis identify the underlying biochemical causes of various disorders so that they can be properly treated. Your exclusive Bio-R supplementation will contain essential vitamins, minerals, amino and fatty acids and other micronutrients that are required to kick-start the restoration process. Specific micronutrient infusions may be used to reinvigorate your body, avoiding medication that can have unpleasant side effects. Our experts will then work with you to create a bespoke diet and lifestyle plan for longterm success. The results will leave you feeling rejuvenated, physically energised and psychologically positive. STAGE 01 Assessment of health, nutrition & lifestyle Comprehensive biomolecular laboratory tests STAGE 02 Unique micronutrient formula Meeting to discuss comprehensive lab test results and your personal plan Specific tailor-made lifestyle plan STAGE 03 Ongoing support and follow-up for a long-term success 06

Biomolecular Restoration revitalises your life Bio-R can lead to numerous health benefits, including: STAGE 01 The ultimate purpose of Bio-R is to re-energise you, both mentally and physically, in order to achieve your chosen goals. For some clients this may mean seeking to enjoy a dynamic and challenging lifestyle, whilst still looking and feeling great. Others may choose Bio-R as a means to maintain optimum health by reducing the chances of chronic illness. Revitalisation and energy boost Efficient detox and sustainable weight loss Improved physical fitness and performance Mindfulness, self-awareness and mental strength Sharper cognitive skills and brain efficiency Significant stress release and relaxation Strengthened immune system Stable emotional balance Optimised sleep quality Anti-ageing and cellular protection Accelerated regeneration processes Skin enhancement Improved overall well-being Bio-R can be fully tailored to your unique requirements, based on the results of laboratory tests, health issues and expectations. Not only will you receive a bespoke formulation of micronutrients, but also our Bio-R Expert Team will provide expert mentoring to create your own personal lifestyle plan. So whether your goals include weight loss, reducing high cholesterol and blood sugar levels, beginning a physical training regime, or simply feeling and looking younger and more energetic, Bio-R can be tremendously beneficial. 07

The nature of well-being Maintain physical and psychological health STAGE 02 Bio-R relieves metabolic stress, harmful oxidation, and dysfunction at a cellular level. Most diseases and health problems in modern society are associated with biochemical deficiencies and metabolic stress, including: Depression, anxiety and emotional instability Insomnia, burnout and chronic fatigue Overweight and cravings Insulin resistance and type 2 diabetes Metabolic syndrome and cardiovascular risk factors (e.g. high blood pressure, high cholesterol etc.) Reduced sex drive Skin problems Weakened immune system Our aim is to enable you to maintain the physical and psychological health you need to feel happy and energised. Benefits of Bio-R can include efficient weight loss, detox and anti-ageing. It can also reduce risk factors for lifestyle-related illnesses, such as type 2 diabetes or cardiovascular diseases. 08

Why is Bio-R so effective? We know most diets are ineffective in the long term because people are unable to incorporate a uniform diet into their lives. Bio-R is different because it is tailored to each client. Your personalised lifestyle plan will encompass diet, physical exercise and resource management. With the help of expert mentoring from our team, it is possible to lead a dynamic and fulfilled life, whilst maintaining optimum health. STAGE 03 The rejuvenation process requires an understanding of metabolic processes in life that make us feel happy and contented. Besides, personalised supplementation, diet and lifestyle play a major role by helping to keep our biochemistry in harmony. SPECIFIC TAILOR-MADE LIFESTYLE PLAN: Tailored lifestyle plan (nutrition, physical activity, resource management) Personalised micronutrient supplementation and diet counselling Ongoing support and follow-up meeting to discuss genetic results 09

Bio-R overview and features Restoration: Specific micronutrient infusions Tailored micronutrient supplementation (personalised formula) Specific detox and hormonal rebalancing Our most popular s include the following elements: Restoration of healthy gastrointestinal microbiome Health and lifestyle assessment: Medical history Current health status Body composition/body fat mass/fat free mass Personal goals Comprehensive laboratory tests and analysis to detect: Micronutrient deficiencies e.g. vitamins, minerals, amino acids, fatty acids Cellular ageing factors e.g. oxidative, nitrosative and inflammatory stress Mitochondrial stress/impaired energy synthesis Imbalances in neurotransmitters and hormones Adrenal fatigue/stress profile Allergy predisposition Heavy metal loading Nutritive hypoglycemia Microbiome imbalances Genetic predispositions/nutri-genetics Continuing Care: Ongoing support (to enable a successful transition to daily life) Expert mentoring (via Skype/email/sms etc.) Laboratory re-testing and lifestyle adaptation Lifestyle: Personalised workout and fat-burning plans Mindfulness and stress management Bespoke supportive treatments (e.g. laser acupuncture, reflexology, body balance and harmonisation etc.) Expert training for your own personal staff (e.g. instructions for chef etc.) 10

Bio-R Assessment of health and the style of living Ultimate detox Meals prepared by your gourmet chef 7 days a week features Family anamnesis Efficient weight loss Training of your personal chef Check-up of vital parameters Metabolic/hormonal rebalancing Medical concierge consultation Body composition analysis to detect body fat and measure absolute and relative muscle mass Restoration of sleep architecture BIO-R PROGRAMME BOOSTER TREATMENTS*: Comprehensive biomolecular laboratory tests: Mindfulness and stress management Specific micronutrient infusions Micronutrient deficiencies e.g. vitamins, minerals, amino acids, fatty acids Tailor-made meal plans Reflexology Cellular ageing factors e.g. oxidative, nitrosative and inflammatory stress Personalised workout and instructions by our expert personal trainers Body balance Mitochondrial stress/ impaired energy synthesis Laboratory retesting and fine-tuning Acupuncture Imbalances in neurotransmitters and hormones Adrenal fatigue/stress profile Allergy predisposition Heavy metal loading Continuous support according to the chosen Ongoing support to allow a successful transition to one s personal, daily life. Bespoke lifestyle plan Colon Hydrotherapy Microbiome restoration Mental strengthening Skin enhancement Microbiome imbalances VIP service upon arrival and departure including transfers to and from Zurich Airport for 1 person Spa treatments *Note: Bio-R booster treatments & Double Check specific medical check-ups available at extra cost except for Ultimate. Genetic predispositions/nutri-genetics Composition of a unique set of personalised micronutrient formulas including a 2-3 month supply Impact detox 12-13 nights in one of our 5-star private residences, with personal butler/chef, laundry and dry-cleaning service and personal chauffeur Assistant to coordinate your days from Monday to Friday DOUBLE CHECK SPECIFIC HEALTH CHECK-UPS*: Double Check specific health check-ups Personal file containing all the Double Check medical reports 11

Our Bio-R s We offer a wide range of Bio-R packages that can be tailored to your requirements. Our Ultimate rejuvenation experience includes a 2-week or longer stay in one of our luxury residences, followed by unlimited aftercare for an extended period. During your time in Zurich, your needs will be attended to by a personal butler/chef, with maid service and a chauffeur. We also offer our non-residential s, Bio-R Essential and Bio-R Impact, that range from 1 to 3 months in duration. We are happy to supply further details upon request. Each of our s is individually designed to achieve maximum positive results in the time available to each client. However, serious biomolecular imbalances that have led to major physical or psychological disorders may require longer treatment s combined with conventional medicine. Please contact us for details of our various Bio-R s and to discuss how Bio-R can help to rejuvenate your life. Bio R Tel: +41 43 541 11 52 info@bio-r.ch www.bio-r.ch Double Check Zollikerstrasse 60 8702 Zurich-Zollikon Switzerland Tel: +41 44 212 11 00 care@doublecheck.ch www.doublecheck.ch 12

Bio-R Essential Innovative medical detox and rejuvenation, exclusively personalised to your individual biochemical needs for significant results, focusing on the following benefits: Bio-R Essential is an innovative nonresidential for general wellbeing and rejuvenation. It is ideal for clients with a challenging lifestyle who wish to maintain their general level of good health, whilst boosting body functions and enhancing well-being. It aims to identify any imbalances in your personal biochemistry at an early stage in order to reduce the risk of weight gain, premature ageing and chronic illness. non-residential IN-DEPTH AWARENESS OF PERSONAL HEALTH RISK FACTORS HEALTH IMPROVEMENT AND PREVENTION REVITALISATION AND ENERGY BOOST ANTI-AGEING AND CELLULAR PROTECTION This is a 1-2 month that includes comprehensive, in-depth lab tests and a personalised health strengthening and maintenance plan, including tailored micronutrient supplementation as well as nutritional and lifestyle coaching with an additional 2-3 month supply of micronutrients. All treatments and expert mentoring sessions are tailored to meet your individual biochemical needs. OPTIMISED SLEEP QUALITY IMPROVED OVERALL WELL-BEING 13

Bio-R Essential Comprehensive biomolecular laboratory tests: Assessment of health and the style of living BIO-R PROGRAMME BOOSTER TREATMENTS*: includes: Micronutrient deficiencies e.g. vitamins, minerals, amino acids, fatty acids Family anamnesis Specific micronutrient infusions Reflexology Check-up of vital parameters Cellular ageing factors e.g. oxidative, nitrosative and inflammatory stress Mitochondrial stress/ impaired energy synthesis Imbalances in neurotransmitters and hormones Adrenal fatigue/stress profile Body composition analysis to detect body fat and measure absolute and relative muscle mass Composition of a unique set of personalised micronutrient formulas including a 2-3 month supply Bespoke lifestyle plan Body balance Acupuncture Colon Hydrotherapy Microbiome restoration Mental strengthening Skin enhancement ADD-ONS AT EXTRA COST: Metabolic/hormonal rebalancing Allergy predisposition Continuous support according to the chosen Spa treatments DOUBLE CHECK SPECIFIC HEALTH CHECK-UPS*: Heavy metal loading Laboratory retesting and fine-tuning Double Check specific health check-ups *Note: Bio-R booster treatments & Double Check specific medical check-ups available at extra cost except for Ultimate. Genetic predispositions/nutri-genetics (included only in Bio-R Essential Genetics ) Medical concierge consultation Personal file containing all the Double Check medical reports 14

Bio-R Impact Bio-R Impact is an innovative non-residential for deep rejuvenation. It is ideal for clients who wish to prioritise sustainable weight loss, and/or the release of metabolic stress, insulin resistance (pre-diabetes) and cardiovascular risk factors. It also supports the restoration of restful sleep, anti-ageing and correction of emotional imbalances. non-residential Innovative medical detox, weight loss and rejuvenation, exclusively personalised to your individual biochemical needs for significant results, focusing on the following benefits: IN-DEPTH AWARENESS OF PERSONAL HEALTH RISK FACTORS EFFICIENT DETOX AND SUSTAINABLE WEIGHT LOSS HEALTH IMPROVEMENT AND PREVENTION IMPROVED PHYSICAL FITNESS AND PERFORMANCE REVITALISATION AND ENERGY BOOST ANTI-AGEING AND CELLULAR PROTECTION STRENGTHENED IMMUNE SYSTEM SIGNIFICANT STRESS RELEASE AND RELAXATION This is a 3-month that includes a highly personalised lifestyle enhancement plan. All treatments and expert mentoring sessions are fully tailored to meet your individual biochemical needs. OPTIMISED SLEEP QUALITY STABLE EMOTIONAL BALANCE IMPROVED OVERALL WELL-BEING ACCELERATED REGENERATION PROCESSES 15

Bio-R Impact Comprehensive biomolecular laboratory tests: Micronutrient deficiencies e.g. vitamins, minerals, amino acids, fatty acids Body composition analysis to detect body fat and measure absolute and relative muscle mass Composition of a unique set of personalised micronutrient formulas including a 2-3 month supply BIO-R PROGRAMME BOOSTER TREATMENTS*: Specific micronutrient infusions includes: Cellular ageing factors e.g. oxidative, nitrosative and inflammatory stress Metabolic/hormonal rebalancing Reflexology Mitochondrial stress/ impaired energy synthesis Impact detox Body balance Imbalances in neurotransmitters and hormones Adrenal fatigue/stress profile Allergy predisposition Heavy metal loading Efficient weight loss Tailor-made meal plans Mindfulness and stress management Continuous support according to the chosen Acupuncture Colon Hydrotherapy Microbiome restoration Mental strengthening Skin enhancement ADD-ONS AT EXTRA COST: Genetic predispositions/nutri-genetics (included only in Bio-R Impact Genetics ) Assessment of health and the style of living Ongoing support to allow a successful transition to one s personal, daily life. Bespoke lifestyle plan Medical concierge consultation Spa treatments DOUBLE CHECK SPECIFIC HEALTH CHECK-UPS*: Double Check specific health check-ups *Note: Bio-R booster treatments & Double Check specific medical check-ups available at extra cost except for Ultimate. Family anamnesis Check-up of vital parameters Training of your personal chef Laboratory retesting and fine-tuning Personal file containing all the Double Check medical reports 16

Bio-R Ultimate Our exclusive Bio-R Ultimate residential is our most comprehensive package to date, which is fully tailored to your individual needs. It includes a two-week or longer stay at one of our luxury residences whilst you relax, rejuvenate and detox, followed by a tailored aftercare plan. The focuses on the following benefits: Bio-R Ultimate is ideal for clients who wish to maximise their potential for physical and emotional well-being. Benefits can include sustainable weight loss, and/or the release of cellular and metabolic stress, insulin resistance (pre-diabetes) and reduction of risk factors for cardiovascular diseases. The includes a highly personalised lifestyle enhancement plan and nutri-genetic tests to identify the level of detox needed, any intolerances (lactose, gluten etc.) as well as any other specific predispositions. This allows for even more personalised risk prevention and long-term health. The includes constant access to our interdisciplinary Bio-R Expert Team who provide mentoring to assist you with your chosen goals, such as detox and significant weight loss, emotional balance and restful sleep, anti-ageing and deep rejuvenation of body and mind. residential IN-DEPTH AWARENESS OF PERSONAL HEALTH RISK FACTORS HEALTH IMPROVEMENT AND PREVENTION REVITALISATION AND ENERGY BOOST ANTI-AGEING AND CELLULAR PROTECTION OPTIMISED SLEEP QUALITY IMPROVED OVERALL WELL-BEING EFFICIENT DETOX AND SUSTAINABLE WEIGHT LOSS IMPROVED PHYSICAL FITNESS AND PERFORMANCE STRENGTHENED IMMUNE SYSTEM SIGNIFICANT STRESS RELEASE AND RELAXATION STABLE EMOTIONAL BALANCE ACCELERATED REGENERATION PROCESSES IMPROVED COGNITIVE SKILLS AND BRAIN EFFICIENCY MINDFULNESS, SELF-AWARENESS AND MENTAL STRENGTH REHABILITATION (e.g. after surgery) SUSTAINABILITY IN PERSONAL DAILY LIFE All treatments and expert mentoring sessions are fully tailored to meet your individual biochemical needs. During your stay at one of our 5-star villas, a private butler & chef will attend to your needs, along with a chauffeur and laundry service. We also offer spa and body treatments which your hospitality manager will be happy to arrange for you. Tailored ongoing support will make your success sustainable so that you profit from a significant and long term improvement in quality of life. 17

Bio-R Assessment of health and the style of living Ultimate detox Meals prepared by your gourmet chef 7 days a week Ultimate Family anamnesis Efficient weight loss Training of your personal chef Check-up of vital parameters Metabolic/hormonal rebalancing Medical concierge consultation includes: Body composition analysis to detect body fat and measure absolute and relative muscle mass Restoration of sleep architecture BIO-R PROGRAMME BOOSTER TREATMENTS*: Comprehensive biomolecular laboratory tests: Mindfulness and stress management Tailor-made meal plans Specific micronutrient infusions Reflexology Micronutrient deficiencies e.g. vitamins, minerals, amino acids, fatty acids Cellular ageing factors e.g. oxidative, nitrosative and inflammatory stress Personalised workout and instructions by our expert personal trainers Laboratory retesting and fine-tuning Body balance Acupuncture Mitochondrial stress/ impaired energy synthesis Imbalances in neurotransmitters and hormones Adrenal fatigue/stress profile Continuous support according to the chosen Ongoing support to allow a successful transition to one s personal, daily life. Colon Hydrotherapy Microbiome restoration Mental strengthening Allergy predisposition Bespoke lifestyle plan Skin enhancement Heavy metal loading VIP service upon arrival and departure including transfers to and from Zurich Airport for 1 person Spa treatments *Note: Bio-R booster treatments & Double Check specific medical check-ups are included only in Ultimate and available at extra cost in Essential and Impact s. Microbiome imbalances Genetic predispositions/nutri-genetics Composition of a unique set of personalised micronutrient formulas including a 2-3 month supply 12-13 nights in one of our 5-star private residences, with personal butler/chef, laundry and dry-cleaning service and personal chauffeur Assistant to coordinate your days from Monday to Friday DOUBLE CHECK SPECIFIC HEALTH CHECK-UPS*: Double Check specific health check-ups Personal file containing all the Double Check medical reports 18

Bio-R Essential Bio-R Impact Bio-R Ultimate Bio-R IN-DEPTH AWARENESS OF PERSONAL HEALTH RISK FACTORS IN-DEPTH AWARENESS OF PERSONAL HEALTH RISK FACTORS IN-DEPTH AWARENESS OF PERSONAL HEALTH RISK FACTORS s HEALTH IMPROVEMENT AND PREVENTION HEALTH IMPROVEMENT AND PREVENTION HEALTH IMPROVEMENT AND PREVENTION health benefits REVITALISATION AND ENERGY BOOST REVITALISATION AND ENERGY BOOST REVITALISATION AND ENERGY BOOST overview ANTI-AGEING AND CELLULAR PROTECTION ANTI-AGEING AND CELLULAR PROTECTION ANTI-AGEING AND CELLULAR PROTECTION OPTIMISED SLEEP QUALITY OPTIMISED SLEEP QUALITY OPTIMISED SLEEP QUALITY IMPROVED OVERALL WELL-BEING IMPROVED OVERALL WELL-BEING IMPROVED OVERALL WELL-BEING EFFICIENT DETOX AND SUSTAINABLE WEIGHT LOSS EFFICIENT DETOX AND SUSTAINABLE WEIGHT LOSS EFFICIENT DETOX AND SUSTAINABLE WEIGHT LOSS IMPROVED PHYSICAL FITNESS AND PERFORMANCE IMPROVED PHYSICAL FITNESS AND PERFORMANCE IMPROVED PHYSICAL FITNESS AND PERFORMANCE STRENGTHENED IMMUNE SYSTEM STRENGTHENED IMMUNE SYSTEM STRENGTHENED IMMUNE SYSTEM SIGNIFICANT STRESS RELEASE AND RELAXATION SIGNIFICANT STRESS RELEASE AND RELAXATION SIGNIFICANT STRESS RELEASE AND RELAXATION STABLE EMOTIONAL BALANCE STABLE EMOTIONAL BALANCE STABLE EMOTIONAL BALANCE ACCELERATED REGENERATION PROCESSES ACCELERATED REGENERATION PROCESSES ACCELERATED REGENERATION PROCESSES IMPROVED COGNITIVE SKILLS AND BRAIN EFFICIENCY IMPROVED COGNITIVE SKILLS AND BRAIN EFFICIENCY IMPROVED COGNITIVE SKILLS AND BRAIN EFFICIENCY Bio-R Essential Bio-R Impact non-residential MINDFULNESS, SELF-AWARENESS AND MENTAL STRENGTH REHABILITATION (e.g. after surgery) MINDFULNESS, SELF-AWARENESS AND MENTAL STRENGTH REHABILITATION (e.g. after surgery) MINDFULNESS, SELF-AWARENESS AND MENTAL STRENGTH REHABILITATION (e.g. after surgery) Bio-R Ultimate residential SUSTAINABILITY IN PERSONAL DAILY LIFE SUSTAINABILITY IN PERSONAL DAILY LIFE SUSTAINABILITY IN PERSONAL DAILY LIFE 19

Please contact us for details Bio R Tel: +41 43 541 11 52 info@bio-r.ch www.bio-r.ch Double Check Zollikerstrasse 60 8702 Zurich-Zollikon Switzerland Tel: +41 44 212 11 00 care@doublecheck.ch www.doublecheck.ch

www.bio-r.ch