DOMENICO SANTORO M.D. Associate Professor of Nephrology

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DOMENICO SANTORO M.D. Associate Professor of Nephrology CURRICULUM VITAE Revised: 2010/12

Birth Date: March 15, 1969 Birth Place: Office Address: E-mail address: Messina, Italy AOU G.Martino University of Messina Unit of Nephrology and Dialysis Department of Internal Medicine Via Consolare Valeria 98124 Messina Italy santisi@hotmail.com; dsantoro@unime.it Office Telephone: 090 221-2331 Fax No.: 090 2925899 Education and Training: 1987 Diploma in Classical Literature 1993 Medical Degree with distinction at University of Messina (Degree thesis: Renal Functional Reserve in Single Kidney Patients) 1995 Stage of Clinical and Research Activity, with a particular interest in renal biopsy carried out with traditional methods and in molecular biology at the University of Bari, Division of Nephrology, headed by Prof. FP Schena 1996-1998 Collaboration with the Department of Biomorphology University of Messina, regarding the study on the Main Extracellular Matrix Components at electron microscopy. 1996-2003 Member of the National Directive Technical Committee. Member of the National Committee of Dialysis and Transplantation Italian Registry. Member of the scientific committee for drawing up the Sicilian Registry of Dialysis and Transplantation, contributing actively to the drafting of two books and the creation of a web page on the Italian Society of Nephrology web site (www.sinitalia.org/registri/sicilia/introduction.html),. 1999 One Year Fellowship, abroad sponsored by the University of Messina, at the Department of Pathology, Cedars-Sinai Medical Center (Los Angeles-California) under the guidance of Dr Arthur Cohen, head of the Department of Renal Pathology. During that period, Dr Santoro made a thorough of a renal disease diagnosis by using the light microscopy, immunofluorescence and electron microscopy and took part in clinico-pathological studies which then resulted in abstracts in international meetings and scientific papers. 1999 Visiting fellow for two weeks at the Division of Nephrology at Baylor College of Medicine (Houston-Texas) directed by Dr Garabed Eknoyan 2002 Visiting fellow for two weeks at the Division of Nephrology and Hypertension at Harbour UCLA Los Angeles directed by Dr Joel Kopple. Board Certification: 1993 Medical Degree with distinction at University of Messina 1993 License for Medical Practice 2

1997 Specialty Training in Renal Medicine 1993-97 with distinction at University of Messina Academic achievements 1993 Medical Degree thesis: Renal Functional Reserve in Single Kidney Patients 1997 Specialty Degree in Renal Medicine thesis: TGF-beta and extracellular matrix changes in ADPKD: immunohistochemical study at CLSM Positions Held: Academic activity 2005- Assistant Professor of Nephrology; School of Renal Medicine University of Messina. 2007- Assistant Professor of Nephrology; School of Medicine University of Messina. 2007- Assistant Professor of Physiopathology of Human Disease; School of Medicine University of Messina. 2008 Assistant Professor of Nephrology; Degree Nursing Science University of Messina. Reggio Calabria Venue. 2009- Assistant Professor of Nephrology; Degree Nursing Science University of Messina. Syracuse Venue 2017 Associate Professor of Nephrology University of Messina Hospital As a Medical Student: 1991-1993 Internal Medicine Department. University of Messina As a Resident: 1993-1997 Division of Nephrology Department. University of Messina As a Medical Director:: 2002-2003 LABOS Nephrology and Dialysis Center As a Medical Doctor working for the National Health Service: 2000-2002 Medical Office of medical units in Messina County 2004 Medical Office of medical units in Messina County As a Nephrologist: 1997-1998 and 2000-2003 AMOS Nephrology and Dialysis Center 2000-2001 CESAR Nephrology and Dialysis Center 2001 Padre Pio Nephrology and Dialysis Center 2004-2006 Unit of Nephrology and Dialysis San Vincenzo Taormina Hospital 2006- Unit of Nephrology and Dialysis, University of Messina Scientific Collaborations: 1993- Prof. G.Bellinghieri: Division of Nephrology and Dialysis at University of Messina 1995 Prof. FP Schena: Chair of Nephrology, University of Bari 1996-1998 Prof. L. Magaudda: Department of Biomorphology University of Messina 1999- Prof. AH Cohen: Division of Renal Pathology at Cedars-Sinai Medical Center UCLA Los Angeles 2002 Prof. JD Kopple: Division of Nephrology and Hypertension at Harbour UCLA Los Angeles 2012 Prof. Ali Gharavi: Division of Nephrology and Hypertension a Columbia University 3

2012 Prof. Ghiggeri Gianmarco: Division of Nephrology at Gaslini Genova 2012 Prof. Francesco Scolari: Division of Nephrology and Dialysis, University of Brescia. Study Groups: National Italian Registry of Dialysis and Transplantation Renal Immunopathology Sicilian Regional Study Group Renal Immunopathology Italian Study Group Chronic Renal Failure Italian Study Group Awards 1992 Scholarship, by merit, awarded by the University Organization of Messina. 1993 Scholarship, by merit, awarded by the University Organization of Messina. 1999 One year research fellowship abroad awarded by the University of Messina and carried out at the Division of Renal Pathology, Cedars Sinai Medical Center UCLA Los Angeles 1999 Grant awarded by the International Society of Nephrology on the occasion of the XVth International Congress of Nephrology (Buenos Aires - Argentina) from 2 to 6 May 1999 As Responsible in Clinical Trials: 1996 Evaluation of the efficacy and tolerability of Manidipine in the tratment of arterial hypertension in patients with chronic renal failure. Randomised, parallel study group versus nifedipine 1998-2003 International Dialysis Outcomes and Practice Pattern Study (I-DOPPS) As Monitor in Clinical Trial 2002- Evaluation of the efficacy and tolerability of Zofenopril. A multicenter randomised parallel study group versus Candesartan As a Member of Scientific Society 1997- Italian Society of Nephrology 1998- Sicilian Regional Society of Nephrology 1999- American Society of Nephrology 2000- European Society of Nephrology 2000- Campano-Sicilian Society of Nephrology 2017-2020: Member of the Italian Society of Nephrology Council Social Activity: Regional Member of the Italian Association of Organ Donation Scientific Activity As Reviewer Nephrology Dialysis and Transplantation Kidney International Journal of Rheumatology Hypertension Research 4

International Journal of Nephrology Kidney & Blood Pressure Research Nephron Experimental International SportMed Journal Arteriosclerosis, Thrombosis, and Vascular Biology Journal of Clinical Rheumatology American Journal of Kidney Disease American Journal of Nephrology PLOS ONE Editorial Board 2009 The Open Drug Safety Journal 2010 The Open Andrology Journal 2011 The Journal of Research On History Of Medicine 2012 World Journal of Nephrology 2012 ISRN Nephrology 2013 Giornale di Tecniche Nefrologiche e Dialitiche 2013 Giornale Italiano di Nefrologia 2016 Journal of Nephrology Associate Editor 2017 BMC Nephrology Papers Scientific Publication on PubMed (181); Scientific Publication on Scopus (189) H index: 22; Author ID: 7006830885; http://orcid.org/0000-0002-4279-6559 Messina 06/02/2018 5