Slide 1. Slide 2. Slide 3 EMS STROKE CARE AND CSTAT OREGON STROKE NETWORK CONFERENCE 2018 SHAWN WOOD, CLINICAL MANAGER DISCLOSURES MY PATH TO EMS

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Slide 1 EMS STROKE CARE AND CSTAT OREGON STROKE NETWORK CONFERENCE 2018 SHAWN WOOD, CLINICAL MANAGER METRO WEST AMBULANCE Slide 2 DISCLOSURES No Financial Conflicts. I work as the Clinical Manager for Metro West Ambulance. I have been a paramedic for 14 years. Member of the Tri-County Protocol Development Committee. Slide 3 MY PATH TO EMS Emergency! U of O SOJ Kitchen Back to School->OHSU/OIT Metro West Ambulance

Slide 4 EMS: EMERGENCY MEDICAL SERVICES Respond, provide emergency stabilization and transport...usually to the closest hospital. That changed with TRAUMA. Specifically with the publication of The 2011 Guidelines for Field Triage of Injured Patients: Recommendations of National Expert Panel on Field Triage (Although here in the Portland area we were already doing this!) STEMI Care: In the early 2000 s with the increased use of field 12-lead EKGs, and advances of cardiac catheterization, it began to matter where we brought our STEMI patients. Slide 5 EMS: STROKE CARE STROKE Care: There are about 795,000 strokes that occur annually. 87% of these strokes are ischemic strokes. Prompt identification and TIME of onset is what mattered. The 3 Hour Window : tpa (Tissue plasminogen activator) administration. Some benefit at 90 days post-treatment. (NINDS Trial, 1995) Anything beyond 3 hours... I am sorry, you should have called sooner....code 1. Transporting for rehabilitation purposes. Slide 6 EMS STROKE SCREENS-PROTOCOL Cincinnati Pre-Hospital Stroke Screen: 1. Facial Droop: Smile and show your teeth. 2. Arm Drift: Hold arms out with palms up and close eyes. 3. Speech: You can t teach an old dog new tricks or It never rains in Oregon.

Slide 7 EMS STROKE STROKE SCREEN- PROTOCOL Screening Criteria: Los Angeles Pre-Hospital Stroke Screen Over 45 years old No history of seizures Neurologic symptoms started to present within the last 24 hours Pt is ambulatory prior to the event; Patient is not hospitalized Blood sugar is 60-400 mg/dl Unilateral (and not bilateral) exhibition of Facial Droop, Grip weakness, Arm weakness or other observable motor asymmetries IF criteria was met, EMS would consider calling a stroke activation, and transport code 3 to the closest primary stroke center. Slide 8 EMS STROKE CARE On the streets, there seemed to be some word of extending that 3 hour window to 4.5 hours. 2015- Endovascular thrombolytic and thrombectomy trials being performed. For EMS, it is a BIG Well, now what is the window?? Slide 9 STROKE: LARGE VESSEL OCCLUSION Acute ischemic stroke related to intracranial large vessel occlusion constitutes about 10% of all stroke patients. Intracranial large vessel occlusion is life-threatening and symptoms are typically profound. These patients are less likely to respond to IV- tpa because of the significant clot burden. Recanalization rates for this subgroup of patients are between 13 and 50% -Vivek Deshmukh, M.D., FACS

Slide 10 MECHANICAL THROMBECTOMY MATURES SWIFT-PRIME randomized trial of ischemic stroke patients treated with tpa alone versus thrombectomy using the new SOLITAIRE revascularization device (Stent retrieval) with and without IV tpa: 60% of those who received both thrombectomy and IV tpa gained functional independence versus only 30% with tpa alone. Slide 11 POSITIVE EMBOLECTOMY TRIALS Slide 12 HOW DOES THIS IMPACT EMS?

Slide 13 EMS STROKE PROTOCOL DEVELOPMENT Often a chaotic, uncontrolled environment. Family sometimes not available for history gathering or consult. Other times family is there, but becomes more of a disruption to care. Primary Stroke Centers vs Comprehensive Stroke Centers (or other neuro-endovascular care hospitals) and location comparative to scene location. Early identification and early imaging are CRITICAL! Slide 14 DEVELOPMENT OF THE 2017 EMS STROKE PROTOCOL In early 2016, the Tri-County Protocol Development Committee began to discuss how to identify LVO in the field. EMS Medical Directors met with area neurologists Reviewed different scoring tools: CSTAT, LAMS, RACE...and others. Taking into consideration how to keep the protocol as operational ( easy ) as possible. Slide 15 2017 EMS PROTOCOL DEVELOPMENT

Slide 16 NOT ALL VARIABLES ARE EQUAL Most Reliable Predictors: Language function Motor power in the arm or leg Next Most Reliable Items: Facial weakness Level of consciousness Least Reliable Items: Sensory function, speech, cerebellar signs, visuospatial dysfunction and visual fields Slide 17 CSTAT: CINCINNATI STROKE TRIAGE ASSESSMENT TOOL Slide 18 CSTAT PERFORMANCE ON DETECTION OF LVO

Slide 19 INTERRATER RELIABILITY Greatest Interrater Reliability: Arm and leg strength evaluations Least Interrater Reliability: Facial movement, limb ataxia, neglect, level of consciousness, and dysarthria had the least reliability. Slide 20 2017 EMS STROKE PROTOCOL: PORTLAND STROKE SCALE Speech deficit Slide 21 2017 EMS STROKE PROTOCOL: PORTLAND STROKE SCALE If patient is positive for stroke using the PSS (Portland Stroke Scale), then we move to CSTAT. If patient is within 20 min of an interventional stroke center, patient should be transported to that center. If the scene is greater than 20 min from an interventional stroke center, we should transport to the closest primary stroke center.

Slide 22 EMS PROTOCOL CSTAT DEPLOYMENT CHALLENGES How do we train 120+ MWA paramedics (Not to mention all of the fire agency paramedics and EMTs? 20 min from scene to interventional facility. (Time of day, route, paramedic/emt judgement-subjective) Hedging your bets...take everyone to an interventional facility! WRONG Hospital A doesn t take strokes-wrong Consistency in reporting of the CSTAT outcome over the radio Slide 23 YOU ARE NOW A PARAMEDIC! You are called to a home in Aloha, OR (Between Beaverton and Hillsboro). You are halfway between Hospital A (PSC) and Hospital B (CSC w/ir) Adult son was visiting his parents when his 75 y/o dad started to fall against the hallway wall while walking to the living room. Son asked what was happening and the father could not say any words. Son assisted him to the ground and called EMS (YOU!) PMHX: A-Fib (not on thinners), colon cancer 10 years ago. Slide 24 YOU ARE THE PARAMEDIC Vital signs: 158/90, HR 72 irregular, RR 14 CBG is 90mg/dl Neuro exam: Pupils equal and reactive, R sided weakness, and he cannot follow simple commands or tell you what city is in or that he is in his home. Portland Stroke Scale: Positive or Negative? CSTAT: Positive or Negative? Hospital A or Hospital B? (Pt family says that he always goes to hospital A.)

Slide 25 THANK YOU, DR. JON JUI FOR SHARING INFORMATION AND DATA FROM HIS SLIDES. Slide 26 REFERENCES Jui, Jonathan, MD. mcems stroke update 2018 veccu 083118 vpublic https://www.nasemso.org/meetings/spring/documents/advances-in-stroke-care- Williams-Spring2017.pdf Rush University Medical Center. "Game-changer for stroke treatment: Better function after stroke if clots removed." ScienceDaily. ScienceDaily, 17 April 2015. <www.sciencedaily.com/releases/2015/04/150417085029.htm>. https://oregon.providence.org/forms-and-information/m/mechanical-thrombectomya-new-standard-of-care/ https://journals.heart.org/bloggingstroke/2018/04/18/does-tpa-really-save-lives/ Slide 27 THANK YOU! shawnw@metrowest.fm