Evaluation and Management of Common Knee Disorders

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Evaluation and Management of Common Knee Disorders Chief of Sports Medicine and Shoulder Surgery Beth Israel Deaconess Medical Center Team Physician, Boston Red Sox Harvard Combined Orthopedic Residency Program

Conflict of Interest Arun J. Ramappa, MD I have no financial relationships with commercial entities producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients relevant to the content I am presenting.

Disclosures Major League Baseball (MLB) Arthrex, Naples, FL Ceterix Orthopaedics, Menlo Park, CA ConMed Linvatec, Largo, FL Smith & Nephew, Andover, MA Zimmer, Warsaw, IN

Common Knee Disorders: Overview Anatomy History Common Knee Disorders - Evaluation - Management Injections vetothiais.com

Knee: Bony Anatomy Bones of the Knee Joint - Femur - Tibia - Patella - Fibula Major joints: - Patellofemoral joint - Tibiofemoral joint Tandeter, H.B., et al. Am Fam Physician. 1999

Anterior cruciate ligament (ACL) Knee: Ligament Anatomy Posterior cruciate ligament (PCL) Medial collateral ligament (MCL) Lateral collateral ligament (LCL) orthoinfo.aaos.org

Knee: Anatomy Meniscus - Fibrocartilage Articular cartilage Tandeter, H.B., et al. Am Fam Physician. 1999

Muscles Knee: Muscles/Tendons - Quadriceps - Hamstrings - Patellar Tendon - Popliteus

Knee: History Age Occupation Chief Complaint: Pain, Mechanical Symptoms, Stiffness, and Effusion Location Onset Precipitant or Mechanism of Injury Prior Treatment: RICE, Medication, PT, Injections, and Surgery ironstruck.com Limitations/Progression

Always order weight-bearing knee X-rays initially!

Non weight-bearing X-rays Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Weight-bearing X-rays Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery Anatomy Anterior Posterior (AP) View of Both Knees Weight Bearing 617-667-7678 617-667-7678 bidmc.org/sports

Arun J. Ramappa, MD AP View of Both Knees Weight Bearing BIDMC Sports Medicine & Shoulder Surgery Lateral View of Right Knee Sunrise View of Right Knee 617-667-7678 bidmc.org/sports

Inspection ROM Ligament testing Palpation Provocative maneuvers Physical Examination

Knee Exam: Inspection + ROM Inspection - Effusion - Quad tone ROM Flexion/Extension Passive/Active

MCL LCL ACL PCL Exam: Ligament Exam - Valgus stress at 0 and 30 - Varus stress at 0 and 30 - Lachman maneuver - Anterior drawer - Posterior drawer

Knee Exam: MCL

Knee Exam: ACL

Knee Exam: PCL

Exam: Medial Joint Line

Exam: Lateral Joint Line

Exam: McMurray s Test

Meniscal Tear Common Knee Disorders Anterior Cruciate Ligament (ACL) Tear Patellofemoral Syndrome Osteoarthritis

Case 1 18 y.o. high school senior baseball player Twists knee while swinging Develops pain and knee swelling Unable to resume playing tullahomanews.com

Case 1 Exam: Walks with limp Exam: (+) Effusion Exam: Lachman negative Exam: Unable to fully extend knee mikereinold.com

Two semilunar fibrocartilaginous wedges - Medial: Semicircular - Lateral: Circular (Cshaped) - Medial > Lateral Function: Menisci - Shock Absorber - Load transmission webmd.com Surgery of the Knee, 2002 - Joint stabilizer

Meniscal Tear - History Mechanism of Injury - Twisting - Flexed knee, planted foot - Rotation - Often insidious onset Symptoms - Swelling (gradual) - Recurrent Effusions - Pain (esp. squatting) - Locking (bucket-handle tears) - Popping - Catching

Meniscal Tear - Physical Examination Effusion Joint line tenderness: - Sensitivity 75% - Specificity 28% McMurray s maneuver: - Specificity 97% - Sensitivity 52% Jackson, et al, Annals of Internal Medicine, 2003 Surgery of the Knee, 2002

MRI without WB X-ray

MRI without WB X-ray Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

WB X-rays demonstrate OA Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Total Knee Replacement Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

MRI Unnecessary Unnecessary study MRI: $800-$1500 Lower pt satisfaction: extra visit/cost

Treatment: Meniscal Tear Activity modification Physical therapy Tylenol/NSAIDs Corticosteroid injection Arthroscopy - Meniscectomy bis.gov - Meniscal Repair

Not ALL tears are the same! Unstable tears Degenerative tears Acute, traumatic tears orthoinfo.aaos.org orthoinfo.aaos.org

Treatment for Meniscal Tear + OA Katz, J.N., et al. NEJM. 2013

Meniscectomy Beneficial For Degenerative Tears? Sihvonen, R., et al. NEJM. 2013

Is there a role for surgery in the treatment of meniscal tears?

Yes patients with mechanical symptoms: locking, catching, giving way.* Hurr JR, et al, Knee Surg Sports Traumatol Arthrosc, 2015 Sihvonen R, et al, Annals of Internal Medicine, 2016

Meniscal Tear Classification Longitudinal Bucket-handle Radial Flap Horizontal Cleavage Degenerative Complex

Partial Meniscectomy

Increases load transmission Decreases contact area Partial Meniscectomy Leads to osteoarthritis Surgery of the Knee, 2002

Displaced Bucket Handle Meniscal Tear Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Meniscal Repair Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Meniscal Repair Much less common than partial meniscectomy Longer rehab: crutches/brace Younger patients: success based on vascularity/biology Healing rates: 75-80% Nepple, et al, JBJS, 2012

Case 1: Treatment MRI Reveals displaced meniscal tear Surgery for repair Arun J. Ramappa, MD 617-667-7678 Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery bidmc.org/sports BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Meniscal Tears: Take Home Points! Not all meniscal tears require surgery! Degenerative tears - PT initially - Surgery if PT fails Tears w/ osteoarthritis - Non-surgical approach Acute, traumatic tears - May require early surgery Gray s Basic Anatomy, 2012 Do NOT order an MRI before ordering WB X-rays!

Meniscal Tear Common Knee Disorders Anterior Cruciate Ligament (ACL) Tear Patellofemoral Syndrome Osteoarthritis

19 y.o. female college junior injured knee playing soccer Noncontact injury Felt pop Case 2 Needed assistance off field quotesgram.com

Exam: (+) effusion Exam: decreased range of motion Case 2 Exam: Lachman maneuver equivocal Smith, B.W., Green, G.A. Am Fam Physician. 1995.

Anterior Cruciate Ligament (ACL) Interconnects the femur and tibia - Crosses the PCL within the center of the knee Function: - Restricts anterior translation of tibia - Rotational stability/ prevents shifting while pivoting orthoinfo.aaos.org

Mechanism of Injury: - Typically non-contact - Pivoting or cutting - Contact is usually from lateral side Symptoms: ACL Tear - History - Knee swelling bleacherreport.com - Decreased knee ROM - Instability

ACL Tear: Physical Examination Lachman Maneuver: - Most sensitive - Compare sides - Look for endpoint! Anterior Drawer Test Pivot Shift Test Benjaminse, A., et al. JOSPT. 2006 Gray s Basic Anatomy. 2012

Negative Lachman Maneuver

Positive Lachman Maneuver

MRI Examination of ACL Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

ACL Tear: Treatment Activity modification Wean from brace/crutches PT: Focused on achieving normal knee ROM + quad activation Non-operative - bracing SURGERY!

ACL Tear Incidence Over 200,000 new ACL injuries occur annually in the USA Often occur concomitantly with meniscal tears Females at risk of sustaining ACL injury 2-8x more than males Sutton, K.M., Bullock, J.M. JAAOS. 2013

ACL Tear: Higher Incidence in Females Anatomic (Q Angle, Laxity, and Intercondylar Notch Size) Biomechanical (Landing Position) Environmental (Equipment and Playing Surface) hughston.com Hormonal (Preovulatory > Postovulatory) Beynnon, B.D., et al. J Athl Train. 2008

Younger Patients - Hamstring Tendon Autograft Graft Options - Patellar Tendon Autograft Older Patients - Allograft mayoclinic.org

ACL Reconstruction Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Do Acute ACL Tears Require Early Surgery? Delayed ACL surgery equivalent to early ACL surgery at 2 year follow-up More than 50% of delayed group had ACL reconstruction Frobell, R.G., et al. NEJM. 2010

Risks of Delaying ACL Surgery? Long-term inability to participate in athletics Decrease in quality of life Increase in meniscal injuries Development of osteoarthritis Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports Oiestad, B.E., et al. American Journal of Sports Medicine. 2009

A Cost-Utility Analysis ACL Reconstruction vs. Structured Rehabilitation Reconstruction resulted in incremental cost savings of $50,417 compared to rehabilitation Reconstruction provided an incremental QALY gain of 0.72 compared to rehabilitation Mather III, R.C., et al. JBJS. 2013

Significant knee effusion Case 2: Treatment Intra-articular injury MRI!!: Reveals ACL tear Prehab PT to increase knee ROM + quad strength Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery Surgery: ACL reconstruction w/ autograft 617-667-7678 bidmc.org/sports

ACL Tear: Take Home Points! Typically sustained through noncontact injury Females > Males Reconstruction should be performed in the athletic/active population Do NOT use allograft reconstruction in young patients

Meniscal Tear Common Knee Disorders Anterior Cruciate Ligament (ACL) Tear Patellofemoral Syndrome Osteoarthritis

22 y.o. female collegiate runner with knee pain Pain is dull, aching, and located over anterior aspect of knee Difficulty running without pain Case 3 Reports no mechanical symptoms or instability al.milesplit.com

Exam: Weakness w/ single leg squat Exam: No effusion Exam: Full ROM Exam: Normal ligament laxity Case 3: Exam Exam: (+) Patellar Grind Test Dixit, S., et al. Am Fam Physician. 2007

Patellofemoral Syndrome High risk of development in runners and endurance athletes Mechanism - Overuse (duration or intensity) - Patellar maltracking - Muscular imbalance Symptoms - Dull, aching, anterior knee pain - Often exacerbated with activity cathe.com

Patellofemoral Syndrome: X-Rays JF Sarwark, J.F., et al. AAOS. 2010

Patellofemoral Syndrome - Examination Evaluate flexibility/strength of quads, hip abductors. J Sign Assess knee ROM Evaluate patellar tracking ( J sign) Patellofemoral compression test A. 90 Flexion B. Full Knee Extension Dixit, S., et al. Am Fam Physician. 2007

Single-legged squat

Quadriceps flexibility

Patellar Grind Test

Patellofemoral Syndrome - Treatment Activity Modification RICE NSAIDs/Tylenol Physical Therapy Orthotics and Taping howcast.com Surgery? NO! Barton, C. J., et al. Br J Sports Med. 2011

Non-Operative Treatment Rixe, J.A., et al. The Physician and Sports Medicine. 2013

Non-Operative Treatment Lower extremity stability, strength, and flexibility Core strengthening Hip abductor Hip external rotator strengthening Quad strengthening Hamstring, ITB, and quad stretching McCall, et al. JPO. 1999

Non-Operative Treatment Hip + Quad strengthening Orthotics Patellar Taping Patellar Bracing

Physical Therapy Alba-Martin, P., et al. J Phys Ther Sci. 2015

Foot Orthoses Barton, C. J., et al. Br J Sports Med. 2011

Patellar Taping Paoloni, M., et al. Clin Rheumatol. 2012

Activity modification Structured PT program Case 3: Treatment Patellar taping and orthotics sportsrehabcoach.com NO surgery! Return to running Paoloni, M., et al. Clin Rheumatol. 2012

Patellofemoral Syndrome: Take home points! Managed through non-operative treatment Physical therapy program focused on quad and hip abductor exercises Taping, orthotics, and bracing can also be beneficial NO surgery!

Meniscal Tear Common Knee Disorders Anterior Cruciate Ligament (ACL) Tear Patellofemoral Syndrome Osteoarthritis

57 y.o. female with knee pain for 6 months Pain is localized to the medial aspect of the knee Describes a feeling of weakness and stiffness in the knee Case 4 Reports difficulty walking for prolonged periods of time and ambulating bonejoint.net

Exam: (+) effusion Case 4 Exam: alignment - bowed Exam: reduced ROM and unable to fully extend Exam: ligament exam normal Exam: medial joint line tenderness Exam: BMI > 30

Osteoarthritis History Mechanism - Degenerative process - Develops slowly - Prior injury Symptoms - Swelling - Progressive pain orthoinfo.aaos.org - Decreased knee ROM - Crepitus

Diagnosis: Weight-bearing X-rays!

Osteoarthritis - Examination Varus/valgus alignment Evaluate swelling Assess knee ROM Joint line tenderness Crepitus bonejoint.net

Osteoarthritis: Treatment Rest/PT/ice/activity modification Weight loss/nutritional Counseling Tylenol/NSAIDs Corticosteroid injections Bracing Arthroscopy Joint replacement

AAOS AUC GUIDELINES FOR KNEE OSTEOARTHRITIS 2013 RECOMMENDATION STRENGTH OF RECOMMENDATION 1. SELF EDUCATION, STRENGTHENING STRONG 2. WEIGHT LOSS MODERATE 3. AGAINST ACUPUNCTURE STRONG 4. MEDIAL UNLOADER BRACING INCONCLUSIVE 5. NO LATERAL HEEL INSERT MODERATE 6. NO GLUCOSAMINE/CHONDROITIN STRONG 7. NSAIDS/TRAMADOL STRONG 8. CORTICOSTEROID KNEE INJECTION INCONCLUSIVE

AAOS AUC GUIDELINES FOR KNEE OSTEOARTHRITIS 2013 RECOMMENDATION STRENGTH OF RECOMMENDATION 9. NO HYALURONIC ACID INJECTIONS STRONG 10. GROWTH FACTOR/PRP INJECTIONS INCONCLUSIVE 11. NO NEEDLE LAVAGE STRONG 12. NO ARTHROSCOPIC DEBRIDEMENT STRONG 13. ARTHROSCOPIC MENISCUS SURGERY INCONCLUSIVE 14. OSTEOTOMY LIMITED 15. SPACER DEVICE CONSENSUS

Arthroscopy for Arthritis? Moseley, J.B., et al. NEJM. 2002

Placebo=Arthroscopy for OA Sham surgery vs. arthroscopic debridement vs. arthroscopic lavage 44 % Refusal rate: selection bias Male VA pts: generalizable results? Moseley, J.B., et al. NEJM. 2002

Arthroscopy for Arthritis? Kirkley, A., et al. NEJM. 2008

Osteoarthritis: Total Knee Replacement Arun J. Ramappa, MD BIDMC Sports Medicine & Shoulder Surgery 617-667-7678 bidmc.org/sports

Weight loss Activity modification/pt Case 4: Treatment Corticosteroid injection hellawella.com NO arthroscopy! TKR if symptoms persist

Osteoarthritis: Take home points! Treat the patient not the X-ray! Self management: weight reduction and activity modification Non-operative treatment: PT + corticosteroid injection Viscosupplementation is generally ineffective NO Arthroscopy! Total knee replacement if severely limited

Diagnostic & Therapeutic Best Approach? - Superolateral Chlorhexidine Knee Injections 1. 2. 5 cc!% lidocaine w/o Epinephrine 1-2 cc (40-80 mg) of corticosteroid 3. 4. Angle needle parallel to the femur with knee extended Hermans J, et al. Semin Arthritis Rheum. 2011 Douglas, R. KSRR. 2014

Knee Injection + Aspiration

Special Considerations before Injection Pts with Diabetes - Injection may raise blood glucose levels Pts with HIV Moon, et al, Am J Phys Med Rehabil 2014 - Wary if on protease inhibitor Ex. Ritonavir/Norvir Can cause iatrogenic Cushing s response Maviki, et al, Skeletal Radiol 2013

What About Synvisc? 2012 Anne, W.S., et al. Annals of Internal Medicine. 2012 Jevsevar, D., et al. JBJS. 2015

Evaluation of Common Knee Injuries: Summary When to refer? - ALL Dislocations or instability - Traumatic event with NEW pain or mechanical symptoms - Whenever in doubt bleacherreport.com

Evaluation and Management of Common Knee Injuries Thank you!! Questions please Referral: 617-667-7678 Doctor-Doctor Line: 617-667-2020 bidmc.org/sports mtn.weekly.com aramappa@bidmc.harvard.edu

Thank You aramappa@bidmc.harvard.edu