University of Groningen Hand eczema Coevorden, Anthony Marco van IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2005 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Coevorden, A. M. V. (2005). Hand eczema: clinical efficacy of interventions, and burden of disease s.n. Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date: 10-02-2018
HAND ECZEMA CLINICAL EFFICACY OF INTERVENTIONS, AND BURDEN OF DISEASE
A.M. van Coevorden Cover: Hands and threader by Todd Messegee ISBN: 90-367-2370-1
RIJKSUNIVERSITEIT GRONINGEN HAND ECZEMA CLINICAL EFFICACY OF INTERVENTIONS, AND BURDEN OF DISEASE PROEFSCHRIFT ter verkrijging van het doctoraat in de Medische Wetenschappen aan de Rijksuniversiteit Groningen op gezag van de Rector Magnificus, Dr. F. Zwarts, in het openbaar te verdedigen op woensdag 14 december 2005 om 13.15 uur door Anthony Marco van Coevorden geboren op 4 september 1973 te Groningen
Promotor: Prof.dr. P.J. Coenraads Copromotor: Dr. F.L.P. van Sonderen Beoordelingscommissie: Prof.dr. D.P. Bruynzeel Prof.dr. R.P. Stolk Prof.dr. Å. Svensson
Paranimfen: Dr. M.M. Boomsma Mw.drs. W.G. Kamphof
The financial support from the following institutions is gratefully acknowledged: Abbott, AB Medical prs, Artu Biologicals, Astellas, Bauerfeind, Bipharma, CenE Bankiers, Coloplast, ConvaTec, Fagron, Galderma, GlaxoSmithKline, La Roche-Posay, Laservision Instruments, Leo Pharma, Lohmann & Rauscher, Louis Widmer, Medi Nederland, Novartis, Pharmadeal, Roche, Sanofi-Aventis, Schering-Plough, Serono, Sigma-Tau, Stichting Mileuen Arbeidsdermatologie, Stichting Nationaal Huidfonds, Tramedico Consumer Healthcare, UCB Pharma, Van der Bend, Will Pharma and Wyeth.
Liberdade Ai que prazer Não cumprir um dever, Ter um livro para ler E não o fazer! Ler é maçada, Estudar é nada. O sol doira Sem literatura. Livros são papéis pintados com tinta. Estudar é uma coisa em que está indistinta A distinção entre nada e coisa nenhuma. Grande é a poesia, a bondade e as danças Mas o melhor do mundo são as crianças. Fernando Pessoa 16 de Março 1935 Voor Alexander
CONTENTS Chapter 1 Introduction 11 Chapter 2 Overview of therapeutic studies of treatments for hand eczema the EDEN hand eczema survey 23 Chapter 3 Hand eczema the evidence for treatment questions 37 Chapter 4 Interventions for hand eczema 63 Chapter 5 Chapter 6 Appendix 1 Comparison of oral psoralen-uva with a portable tanning unit at home vs. hospital-administered bath psoralen-uva in patients with chronic hand eczema: an open label randomised controlled trial of efficacy Assessment of severity of hand eczema; discrepancies between patient- and physician-rated scores Comparison of economic outcomes of oral PUVA with a portable tanning unit at home vs. hospital administered bath PUVA in patients with chronic hand eczema 131 143 155 Appendix 2 Severe influenzalike symptoms associated with 8- methoxypsoralen photochemotherapy 163 General discussion 167 Summary 173 Samenvatting 179 Dankwoord 187 Curriculum vitae 191 List of publications 195