Note: Page numbers of article titles are in boldface type. A AEDs. See Automated external defibrillators (AEDs) AF. See Atrial fibrillation (AF) Age as factor in SD in marathon runners, 45 Antiarrhythmic drug therapy exercise testing taking, 57 Arrhythmia(s) sinus, 109 110 ventricular. See Ventricular arrhythmias Arrhythmic syncope, 127 Arrhythmogenesis and, 74 75 Arrhythmogenic right ventricular cardiomyopathy (ARVC) arrhythmic SD in young people due to, 4 5 exercise-induced, 97 105. See also Exercise-induced arrhythmogenic right ventricular cardiomyopathy (EIARVC) 88 ARVC. See Arrhythmogenic right ventricular cardiomyopathy (ARVC) Athlete(s) competitive cardiac screening of exercise testing in, 59 60 EIARVC in factors predisposing to, 101 102. See also Exercise-induced arrhythmogenic right ventricular cardiomyopathy (EIARVC) heart of RV as Achilles heel of, 99 101 ICD in, 123 130. See also Implantable cardioverter defibrillator (ICD), middle-aged/older AF in, 115 121. See also Atrial fibrillation (AF), in middle-aged/older athletes RV of chronic remodeling of, 100 101 SD in apparently normal hearts and, 73 74 and, 73 84. See also syncope in, 85 96. See also Syncope, in athletes ventricular arrhythmias in risk stratification of exercise testing for, 53 64. See also Exercise testing, in risk stratification of ventricular arrhythmias young competitive cardiovascular evaluation of recommendations for, 34 SCD in primary prevention of preparticipation screening in, 13 21. See also Preparticipation screening, in primary prevention of SCD in young secondary prevention of, 23 31. See also Automated external defibrillators (AEDs), in secondary prevention of SCD in young Atrial fibrillation (AF) exercise-related pathophysiology of, 117 118 in middle-aged/older athletes, 115 121 endurance sports related, 117 incidence of, 115 116 increased risk of studies of, 116 117 inflammatory response/endurance sport practice relationship, 118 management of, 119 pathophysiology of, 117 118 prevalence of, 115 116 prevalence of, 115 Atrioventricular (AV) conduction disturbances in, 110 111 Automated external defibrillators (AEDs) in SD prevention in marathon runners, 49 50 in secondary prevention of SCD in young, 26 28 barriers to use of, 27 28 costs related to, 27 implementation-related issues, 27 28 rescuer knowledge of, 28 AV. See Atrioventricular (AV) B Bradyarrhythmia(s), 107 114 described, 107 Card Electrophysiol Clin 5 (2013) 131 135 http://dx.doi.org/10.1016/s1877-9182(13)00027-0 1877-9182/13/$ see front matter Ó 2013 Elsevier Inc. All rights reserved. cardiacep.theclinics.com
132 Bradyarrhythmia(s) (continued ) long-term follow-up of, 111 observational studies, 109 pathophysiology of, 107 109 recommendations related to, 111 112 sinus, 107 Bradycardia sinus, 109 110 Brugada syndrome genetic basis of, 77 78 right precordial early repolarization and differential diagnosis of, 78 79 right precordial and, 75 77 risk stratification for, 79 sport recommendations for patients with, 79 C CAD. See Coronary artery disease (CAD) Cardiac catheterization/cta Cardiac disease. See Heart diseases Cardiomyopathy(ies) (CMPs) competitive sport participation by patients with, 69 70 leisure-time physical/sport activity in patients with, 65 71 examining physician s role in, 67 modality of, 68 69 patient education related to, 69 prescription for, 67 68 recommendations for, 66 67 risks related to, 66 special considerations, 70 in young patients physical education class for, 69 Cardiopulmonary resuscitation (CPR) bystander in SD prevention in marathon runners, 49 50 Cardiovascular disease athletes with known exercise testing in, 55 57 sports and, 126 127 Catecholaminergic polymorphic ventricular tachycardia (CPVT), 58 59 89 Chagas disease CMPs. See Cardiomyopathy(ies) (CMPs) Commotio cordis Computed tomography angiography (CTA) Conduction system disorders arrhythmic SD in young people due to, 6 7 Congenital heart disease Coronary anomalies Coronary artery(ies) congenital anomalies of arrhythmic SD in young people due to, 2 4 Coronary artery disease (CAD) atherosclerotic arrhythmic SD in young people due to, 2 leisure-time sport activities for people with recommendations for, 35 36 CPR. See Cardiopulmonary resuscitation (CPR) CPVT. See Catecholaminergic polymorphic ventricular tachycardia (CPVT) CTA. See Computed tomography angiography (CTA) D Doping substances SCD due to, 7 8 Drug use illicit as factor in EIARVC, 102 E Early repolarization syndrome inferolateral early repolarization and, 79 80 Echocardiography Electrocardiography (ECG) physiologic vs. pathologic abnormalities on in young, 16 Electrophysiologic study ETT. See Exercise treadmill testing (ETT) Exercise AF related to in middle-aged/older athletes, 115 121. See also Atrial fibrillation (AF), in middle-aged/older athletes ARVC due to, 97 105. See also Exercise-induced arrhythmogenic right ventricular cardiomyopathy (EIARVC) benefits of, 43 pathophysiologic changes during ventricular arrhythmias triggered by, 54 55 physiologic adaptations during, 54 RV afterload and work during increase in, 99 ventricular arrhythmias induced by clinical significance of, 57 58 Exercise-induced arrhythmogenic right ventricular cardiomyopathy (EIARVC)
133 clinical relevance of, 102 103 conflicts of interest related to, 103 104 described, 97 99 factors predisposing to, 101 102 funding for, 103 104 perspectives on, 102 103 Exercise testing in cardiac screening of, 59 60 in risk stratification of ventricular arrhythmias in athletes, 53 64 with known cardiovascular disease, 55 57 on antiarrhythmic drug therapy, 57 underlying electrical disease, 56 57 underlying structural disease, 55 56 introduction to, 53 54 Exercise treadmill testing (ETT), 94 G Gender as factor in SD in marathon runners, 45 46 Genetic(s) in Brugada syndrome, 77 78 as factor in EIARVC, 101 102 Genetic testing H HCM. See Hypertrophic cardiomyopathy (HCM) Heart(s) apparently normal SD with, 73 74 Heart disease(s) congenital at risk of arrhythmogenic SD in young people, 1 7. See also specific diseases and Sudden cardiac death (SCD), in young people, cardiac disease at risk of SD in marathon runners due to, 47 48 in young athletes diagnosed at early stage treatment of, 18 19 Hyperthermia Hypertrophic cardiomyopathy (HCM) arrhythmic SD in young people due to, 5 6 exercise testing with, 55 56 Hyponatremia I ICD. See Implantable cardioverter defibrillator (ICD) Illicit drug use as factor in EIARVC, 102 Implantable cardioverter defibrillator (ICD), 123 130 efficacy of sympathetic effect on, 124 125 performance of, 124 126 recommendations related to, 127 128 sports injuries affecting, 125 126 sports participation effects on, 124 described, 123 124 Inferolateral early repolarization benign vs. malignant, 80 81 J-wave amplitude in, 80 race in, 81 ST-segment configuration in, 80 early repolarization syndrome and, 79 80 Italian screening program in primary prevention of SCD in young competitive athletes, 14 16 J J-wave amplitude repolarization, 80 L Leisure-time physical/sport activities in cardiomyopathy patients, 65 71. See also Cardiomyopathy(ies) (CMPs), leisure-time physical/sport activity in patients with people engaged in background of, 33 34 cardiovascular evaluation of, 33 42 discussion, 38 40 individual risk profile in, 36 intended level of physical activity in, 37 levels of evaluation, 37 38 recommendations for, 34 38 for CAD patients, 35 36 at health/fitness facilities, 35 Long QT syndrome 57 M Magnetic resonance imaging (MRI) Marathon runners SCA in SD in, 43 51 age as factor in, 45 causes of, 47 49
134 Marathon (continued ) cardiac diseases, 47 48 noncardiac diseases, 48 49 demographics of, 45 47 epidemiology of, 44 47 gender as factor in, 45 46 incidence of, 44 45 introduction to, 43 44 prevalence of, 46 47 prevention of, 49 50 AEDs in, 49 50 bystander CPR in, 49 50 preparticipation screening in, 50 Master athletes leisure-time sport activities among cardiovascular evaluation of, 33 42. See also Leisure-time physical/sport activities, people engaged in, cardiovascular evaluation of MRI. See Magnetic resonance imaging (MRI) Myocarditis arrhythmic SD in young people due to, 6 N Neurally mediated syncope, 85 86 Noncardiac diseases SD in marathon runners due to, 48 49 P Postexertion collapse Preparticipation screening in primary prevention of SCD in young competitive athletes costs related to, 19 described, 13 14 efficacy of, 18 feasibility of, 19 future directions in, 19 20 Italian screening program, 14 16 physiologic vs. pathologic abnormalities in ECG, 16 treatment of athletes diagnosed with heart diseases at early stage, 18 19 ventricular arrhythmias in, 16 18 R Race repolarization, 81 Right precordial early repolarization Brugada syndrome and differential diagnosis of, 78 79 Right ventricle (RV) as Achilles heel of athlete s heart, 99 101 of athlete chronic remodeling of, 100 101 Right ventricle (RV) afterload during exercise, 99 Right ventricle (RV) load exercise-induced effects on disproportionate RV dysfunction related to, 99 100 Right ventricular outflow tract (RVOT) ventricular tachycardia (VT) RV. See Right ventricle (RV) RVOT VT. See Right ventricular outflow tract (RVOT) ventricular tachycardia (VT) S SCA. See Sudden cardiac arrest (SCA) SCD. See Sudden cardiac death (SCD) SD. See Sudden cardiac death (SCD) Seizure(s) 87 Senior(s) AF in, 115 121. See also Atrial fibrillation (AF), in middle-aged/older athletes leisure-time sport activities among cardiovascular evaluation of, 33 42. See also Leisure-time physical/sport activities, people engaged in, cardiovascular evaluation of Sinus arrhythmias, 109 110 Sinus bradyarrhythmia, 107 Sinus bradycardia, 109 110 Sports cardiovascular diseases and, 126 127 competitive CMPs and participation in, 69 70 disease progression related to, 126 127 leisure-time people engaged in cardiovascular evaluation of, 33 42. See also Leisure-time sport activities, master athletes and middle-aged/senior people engaged in, cardiovascular evaluation of SCD during pathologic substrates of, 1 11. See also Sudden cardiac death (SCD) ST-segment configuration repolarization, 80 arrhythmogenesis and, 74 75
135 mechanisms underlying, 74 75 right precordial Brugada syndrome and, 75 77 SD related to, 73 84 implications for screening, 81 Sudden cardiac arrest (SCA) emergency planning for, 26 management of, 26 27 in marathon runners mortality rates, 23 recognition of, 26 27 survival following determinants of, 23 in young responding to, 27 Sudden cardiac death (SCD) with apparently normal hearts, 73 74 and, 73 84. See also young competitive. See Sudden cardiac death (SCD), in young in marathon runners, 43 51. See also Marathon runners, SD in during sports described, 1 2 doping substances and, 7 8 pathologic substrates of, 1 11 structurally normal heart and, 7 in young epidemiology of, 14 primary prevention of preparticipation screening in, 13 21. See also Preparticipation screening, in primary prevention of SCD in young strategies for limitations of, 25 risk factors for, 24 25 secondary prevention of, 23 31 AEDs in, 26 28. See also Automated external defibrillators (AEDs), in secondary prevention of SCD in young in young people cardiac disease at risk of, 2 7 ARVC, 4 5 atherosclerotic CAD, 2 conduction system disorders, 6 7 congenital anomalies of coronary arteries, 2 4 HCM, 5 6 myocarditis, 6 valve diseases, 6 Sudden death (SD). See Sudden cardiac death (SCD) Syncope T arrhythmic, 127, 85 96 causes of cardiac, 87 89 ARVC, 87 88 bradyarrhythmias, 87 Brugada syndrome, 88 commotio cordis, 88 coronary anomalies, 88 CPVT, 88 89 HCM, 87 long QT syndrome, 88 management of, 92 93 RVOT VT, 88 tachyarrhythmias, 87 nonarrhythmic, 85 87 hyperthermia, 86 hyponatremia, 86 neurally mediated syncope, 85 86 postexertion collapse, 86 seizures, 86 87 diagnosis of, 89 94 cardiac catheterization/cta, 94 ECG in, 91 echocardiography in, 91 electrophysiologic study in, 94 ETT in, 91, 94 genetic testing in, 94 initial work-up in, 89 91 MRI in, 91 management of, 89 94 neurally mediated, 85 86 Tachyarrhythmia(s) V Valve diseases arrhythmic SD in young people due to, 6 Ventricular arrhythmias risk stratification of exercise testing for, 53 64. See also Exercise testing, in risk stratification of ventricular arrhythmias exercise-induced clinical significance of, 57 58 pathophysiologic changes triggering, 54 55 in preparticipation screening for SCD in young, 16 18 W Wolff-Parkinson-White (WPW) syndrome exercise testing with, 57