Clinical management of BRCA mutation carriers and those at high risk of breast cancer. Provisional Program

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Clinical management of BRCA mutation carriers and those at high risk of breast cancer Provisional Program

Thursday, November 22 14.00 18.00 Live operating session - Bilateral risk reducing mastectomy case (D and K) Pre-pectoral implant reconstruction 18.30 21.00 Get together and pre-meeting drinks at Klíníkin Friday, November 23 8.45 9.00 Welcome and opening remarks Kristján Skúli Ásgeirsson Session 1: Risk Reducing Surgery The route to surgery Moderator: Stephen McCulley 9.00 9.15 The why of risk reducing surgery Kevin S. Hughes (Massachusetts General Hospital) 9.15 10.00 Planning RRS The pathway before surgery The Geneticist - Diana Eccles The Specialist Nurse - Nicky Scott The Surgeons - Douglas Macmillan (Nottingham Breast Institute) 10.00 10.15 Pre-mastectomy fat grafting and / or breast lift/reduction in RRS. Kristjan S. Asgeirsson (Nordic and Nottingham Breast Institute) Panel discussion

10.30 11.00 Coffee Break Session 2: Risk Reducing Surgery Implant Recon Moderator: Kristjan S. Asgeirsson 11.00 11.15 Under or over Is over the way to go? 11.15 11.35 Designing the pre-pectoral pocket Douglas Macmillan (Nottingham Breast Institute) 11.35 11.55 Product selection Which implant / mesh Douglas Macmillan (Nottingham Breast Institute) 11.55 12.10 Post-mastectomy fat grafting Susanna Kauhanen 12.10 12.45 Panel Discussion 12.45 13.45 Lunch

Session 3: BRCA related breast cancer Moderator: Douglas Macmillan 13.45 14.00 Risk reducing strategies for the BRCA positive breast cancer survivor Douglas Macmillan 14.00 14.15 BRCA gene mutations and clinical outcomes in young onset breast cáncer, results from the POSH study Professor Diana Eccles, University of Southampton 14.15 14.30 An update on the systemic treatment of BRCA - related breast cáncer NIklas Loman 14.30 14.45 The role of oophorectomy in reducing breast cancer mortality for BRCA mutation carriers after breast cancer Steve Narod 14.45 15.00 Panel discussion and live web-based discussion 15.00 15.30 Coffee break Advertising stands 15.30-16.00 Invited lecture What is the origin of the BRCA mutation? TBA 17.15 Bus trip and Dinner at the Blue Lagoon and Northern Lights

Saturday November 24 Session 4: Non BRCA women at high risk Moderator: Kristjan Asgeirsson 09.00 09.15 What to do about non-brca pathogenic mutation carriers? Steve Narod (Toronto, Canada) 09.15 09.30 Pathological risk lesions and their management. Kevin S. Hughes (Massachusetts General Hospital) 09.30 09.45 What is the risk in women with a strong family history, but test negative for BRCA mutation Diana Eccles / Noomi 09.45 10.15 A new view on DCIS Steve Narod 10.15 10.30 Panel discussion and live web-based discussion 10.30 11.00 Coffee Break Session 5: Identifying BRCA mutation carriers Moderator; Douglas Macmillan

11.00 11.15 Current and future best practice in clinical genetic testing Professor Diana Eccles, University of Southampton 11.15 11.30 Genetic testing: What problem are we trying to solve? Kevin S, Hughes (Massachusetts General Hospital) 11.30 11.45 Is population based genetic testing becoming a reality? Steve Narod (Toronto, Canada) 11.45 12.00 Implications of identifying gene mutation carriers through whole genome studies Niklas Loman 12.00 12.15 What are the caveats to population based genetic testing Diana Eccles (University of Southampton) 12.15 12.30 The impact of more liberal genetic testing in Iceland Vigdís Stefánsdóttir (genetic counsellor, Landspitali University Hosppital, Iceland) 12.30 12.45 Panel discussion and live web-based discussion