Discussion Panel: Integrated Testing and Screening From Primary Care to Public Health

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Analysis. Answers. Action. www.aphl.org Discussion Panel: Integrated Testing and Screening From Primary Care to Public Health

Analysis. Answers. Action. www.aphl.org Anne Gaynor, PhD, Association of Public Health Laboratories Vaneet Arora, MD, Kentucky State Public Health Laboratory Lesley Miller, MD, Emory University School of Medicine Liisa Randall, PhD Massachusetts Department of Public Health

Synergy is the creation of a whole that is greater than the simple sum of its parts

Why Integration? APHL Survey Report Analysis. Answers. Action. National HIV Prevention Inventory https://www.nastad.org/sites/default/files/re sources/docs/2019-nhpi-survey-report.pdf www.aphl.org

Why Integration? Analysis. Answers. Action. Image Credit: https://www.hhs.gov/hepatitis/blog/2019/01/16/new-hivhcv-coinfection-resources-for-providers.html www.aphl.org

Where should there be integration? Ideally everywhere! How to integrate will depend on your Venue/Setting Population Client Preferences Resources Policies and Regulations Analysis. Answers. Action. www.aphl.org

Integration Analysis. Answers. https://www.nastad.org/resource/integrated-testing-toolkit Action. www.aphl.org

Laboratory Testing Integration www.aphl.org/vh On the right side of the page under Other Resources Analysis. Answers. Action. www.aphl.org

Analysis. Answers. Action. www.aphl.org

Routine HCV and HIV Screening at Grady Health System Lesley Miller, MD Associate Professor of Medicine Emory University School of Medicine Medical Director, Grady Liver Clinic CDC HIV Diagnostics Conference March 27, 2019

Disclosures Dr. Miller receives grant funding from Gilead Sciences (FOCUS Program) and Merck & Co. and participates on an advisory board for AbbVie The FOCUS Program is a public health initiative that enables partners to develop and share best practices in routine blood-borne virus (HIV, Hepatitis C, Hepatitis B) screening, diagnosis, and linkage to care in accordance with screening guidelines promulgated by the U.S. Centers for Disease Control and Prevention (CDC), the U.S. Preventive Services Task Force (USPSTF), and state and local public health departments. FOCUS funding supports HIV, HCV, and HBV screening and linkage to the first medical appointment after diagnosis. FOCUS partners do not use FOCUS awards for activities beyond linkage to the first medical appointment.

640,000 137,000 141,000 6,000 2017 Data

Importance of Routine HIV and HCV Screening at Grady At Risk Patient Population High HIV & HCV prevalence High prevalence of risk factors Grady Liver Clinic & Ponce de Leon Center (IDP) Access to specialty care for uninsured patients Low barrier linkage to HIV Providers & HCV medical care Academic internal medicine, emergency medicine residents/faculty Community-based family practice

Evolution of Integrated HCV/HIV Screening 2013-16 Separate HCV and HIV Screening grants and programs 2016 Combined programs Expansion to neighborhood clinics Creation of HCV Screening provider BPA 2017 Expansion to Inpatient Med/Surg Bundled HIV/HCV inpatient BPA 2018 Expansion to Ambulatory Specialty Clinics Bundled HIV/HCV outpatient triage BPA Reflex RNA testing

HCV/HIV Screening: Patient Pathway ASSESS REGISTRATION: Smart algorithm to identify eligible patients OFFER TRIAGE: RN/MA makes an opt-out test offer to eligible patients ORDER Order Signed: RN or Provider signs order RESULTS Preliminary test results appear in EHR (HCV 24 h, HIV 3 h) DISCLOSE HIV: MSW paged; collaborates with the provider to disclose HCV: Navigator or provider disclose after HCV RNA positive (1-2 weeks) LINK MSW or navigator initiates linkage

Grady HCV/HIV EHR Testing Algorithm AGE LAST TEST HCV/HIV Diagnosis Meets Criteria? HCV and/or HIV Screening Tab CMA places order (opt out offer) EHR Logic Triage Navigator Automated Order

Triage: Test Offer Only appears for patients eligible for an offer

HIV and HCV Screening Offer at Triage

Test Acceptance at Triage Triggers Provider BPA

Inpatient HIV/HCV Screening Incorporated into Admission Order Set

Grady HCV Care Cascade October 2015-October 2018 27,059 tested 2,489 HCV Ab + 9% prevalence 1,985 HCV RNA tested 80% tested 1,320 HCV RNA positive 66% viremic 918 linked to care 70% linked

Grady HIV Care Cascade July 2013-October 2018 116, 458 tested 839 new HIV + 0.7% prevalence 459 linked to care 55% linked (68% adjusted*) * Adjusted linkage to care excludes the following patients: deceased, incarcerated, moved, declined, provided incorrect contact information during registration or already in care (previously diagnosed).

Conclusions HCV and HIV testing and linkage to care are feasible and high yield in this safety-net health system Testing reveals high prevalence of both disease and successful linkage to care Bundling HCV and HIV testing increases efficiency and requires coordination, stakeholder investment and a focus on sustainability

Thank you

Massachusetts Department of Public Health Bureau of Infectious Disease and Laboratory Sciences Strengthening Testing and Linkage through Integration of HIV, HCV, and STI Testing in Massachusetts Liisa M. Randall Director, Office of Health Care Planning 2019 HIV Diagnostics Conference

Context & Goals Public Health Laboratory Program Surveillance

Policy and Strategies Enabling policies State appropriations Retained revenue acct Universal coverage No treatment restrictions IDDAP Opioid SPHL capacity Enhanced capacity Automation Co-testing 3rd Party billing Integrated services Targeted Co-testing Submission to MA SPHL Accountable for outcomes SSP expansion Capacity building/ta Surveillance MAVEN Enhanced surveillance ESP TLC

Integrated HIV/HCV/STI/TB Testing System: Massachusetts MA SPHL 48 partner agencies 120+ locations CBOS CHCs Hospitals DOC HOCs SSPs SUD/OTP Mobile

Syringe Services Programs Sterile injection equip. Syringe disposal Overdose prev., naloxone HIV/HCV/STI T&L Referral SUD Tx Prevention, support Locally approved Syringe Services Programs in Massachusetts (as of February POWERPOINT 2019) MAPS https://www.mass.gov/syringe-service-programs 29

Implementing Integration: HIV, HCV, Syphilis Test Volume, 2014-2018 End RT HIV/HCV/SYP & HCV Reflex Automated + HIV/HCV RT Phase Out Data Source: BIDLS/MDPH. Current as of 3/5/19

Impact of Integration: Testing Uptake 2014-2018 Increase: 106% overall 205% HCV 61% syphilis 63% PWID 48% MSM Data Source: BIDLS/MDPH. Current as of 3/5/19

Impact of Integration: Infections Identified, 2014-2018 HIV/HCV/SYP & HCV Reflex HIV/HCV Data Source: BIDLS/MDPH. Current as of 3/5/19

Impact of Integration Increases uptake of testing Related conditions Priority populations Identifies infection Facilitates linkage Strengthens surveillance Enhances capacity

Lessons Learned Feasible Leveraged existing capacity (lab, program) Community-based implementation Self-sustaining Facilitators Enabling policies Collaboration: PHL, Program, Surveillance Capacity enhancement (lab, providers)

Future Refine strategies & tweak investments Optimize targeting and yield Support/facilitate intervention (e.g. PrEP, opioid prevention) Enhance clinical provider education/ta Continue to build PHL capacity HIV NAT, HBV, Other?

Liisa M. Randall, PhD Director, Office of Health Care Planning Bureau of Infectious Disease and Laboratory Sciences Liisa.randall@state.ma.us