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New! with 1064 nm Technology You Trust Innovation You Need SPTL-1 Vbeam Classic Vbeam Perfecta Vbeam Prima First FDA-cleared PDL Proprietary 595 nm wavelength 8 micropulses Dual wavelength Dual cooling More user-friendly features Better treatment experience A recognized leader in vascular treatments, Candela now brings you the latest pulsed-dye laser with more enhancements than ever before.

Clinically proven results across indications Versatile treatments Vbeam Prima is a highly efficient pulsed-dye laser (PDL) used by healthcare providers all over the world to treat a variety of indications for both face and body, including benign vascular, pigmented, and certain non-pigmented lesions, with high patient tolerability and a low incidence of side effects. 1-12 Poikiloderma of Civatte Benign pigmented lesions Deep blue veins Rosacea Browns Venous lakes a Improved with 1064 nm wavelength Port wine stains a Blues Wrinkles Facial and leg telangiectasia Reds Other Inflammatory acne vulgaris Hemangiomas, angiomas, and spider angiomas a Benign cutaneous lesions warts, scars, striae, psoriasis a a Examples of purpuric treatments. A legacy of innovation 1983 Anderson/Parrish MGH/Harvard 1988 SPTL-1 577 nm, first FDA-cleared PDL 1994 SPTL-1b 585 nm 1996 ScleroPlus 585 nm, 590 nm, 595 nm, 600 nm SPTL, selective photothermolysis. 510(k) pre-market noti

Two wavelengths, more treatment parameters Proprietary 595 nm wavelength The 595 nm wavelength deeply penetrates the skin to reach targeted blood vessels. 4 Its energy is absorbed by oxyhemoglobin to coagulate and clear vessels with more tolerability and fewer instances of melanin absorption. 13 Absorption Oxyhemoglobin Melanin Vbeam 595 nm 400 500 600 700 800 Wavelength (nm) Additional 1064 nm wavelength Treat deep blue veins, venous lakes, and wrinkles! 12 Treats blue veins across face and body Minimizes the appearance of wrinkles 595 nm 1064 nm 2000 Vbeam Classic 595 nm 2006 Vbeam Perfecta 595 nm 8 micropulses 2018 Vbeam Prima 595 nm and 1064 nm fication pending review

New features that benefit both the provider and patient experience Achieve greater results in less time 15 mm spot size Larger max treatment spot size and greater max energy with 595 nm 12 mm Faster, more efficient treatments A treatment that requires 100 pulses with a 12 mm spot size can require as few as 64 pulses with a 15 mm spot size VBEAM PERFECTA VBEAM PRIMA Maximum energy 8 J 12 J Maximum spot size 12 mm 15 mm Area covered 1.13 cm 2 1.77 cm 2 Fluence at 12 mm 7.1 J/cm 2 10.6 J/cm 2 50% more powerful

EverC L Patented cryogen-based Dynamic Cooling Device (DCD ) and EverCool contact cooling options Two types of cooling for maximum versatility and epidermal protection Patented DCD scales with fluence to automatically administer consistent epidermal protection With EverCool, you can treat vascular and pigmented lesions at the same time Smart dye life management Dye life meter provides data on remaining dye levels Avoid unexpected treatment interruptions from dye loss Prompts user to schedule preventative maintenance 1 Once-daily system calibration Device is patient- and treatment-ready for the entire day, reducing downtime between patients; no need to recalibrate when changing spot sizes or fluences Zoom handpiece A versatile handheld applicator that allows for very targeted spot size adjustments in increments as small as 0.5 mm Wi-Fi connectivity More accurate remote service diagnostics for faster equipment servicing Guided user interface Intuitive, easy-to-use software with quick access to saved, favorite treatment settings

Powerful results begin with Vbeam Prima Vbeam Prima is the trusted, proven PDL across indications 14 Telangiectasia Baseline Photos are unretouched. Patient treated with Vbeam Prima; individual results may vary. Photos courtesy of E. Victor Ross, MD. 3-month follow-up Pigmentation with EverC L Baseline Photos are unretouched. Patient treated with Vbeam Prima; individual results may vary. Photos courtesy of E. Victor Ross, MD. 3-month follow-up Diffuse redness Baseline Photos are unretouched. Patient treated with Vbeam Prima; individual results may vary. Photos courtesy of E. Victor Ross, MD. 3-month follow-up

Demand the best for your patients Rosacea affects an estimated 415 million people worldwide 15 In a consumer survey, 59% of patients with rosacea weren t aware of laser therapy as a treatment. 16 Only 8% of surveyed patients said they had undergone laser therapy as part of their rosacea treatment plan. 16 Significant improvements in rosacea symptoms with Vbeam Prima 17 In a clinical study, rosacea symptoms were significantly reduced from moderate to mild after 4 treatments. Difficult-to-treat erythema was reduced from severe to mild ~90% of patients had >40% rosacea improvement Baseline 2-month follow-up, post 4 treatments 94% of patients reported being very satisfied with results 17 Photos are unretouched. Patient treated with Vbeam Prima; individual results may vary. Photos courtesy of Eric F. Bernstein, MD, MSE. Minimal adverse side effects reported 17 On a scale of 1 to 10 (10=max), patients reported an average pain score of 5.6 ± 1.8. Most patients reported side effects such as mild edema, mild to moderate erythema, and mild to moderate bruising. These effects resolved within a few days after treatment without intervention.

Experience the benefits of Vbeam Prima for versatile treatments with proven results Larger 15 mm spot size and 50% greater power at 12 J with 595 nm for faster, more efficient treatments Once-daily system calibration for less downtime between treatments, and more efficient treatments when using a variety of settings Smart dye life management for real-time data on remaining dye levels 1064 nm wavelength for deep blue vessel clearance and wrinkle reduction Patented cryogen-based DCD and EverCool contact cooling for maximum epidermal protection and treatment versatility PRODUCT SPECIFICATIONS Laser wavelengths PDL: 595 nm Nd:YAG laser: 1064 nm Laser pulse repetition rate PDL: Up to 1.5 Hz Nd:YAG laser: Up to 10 Hz Laser pulse duration PDL: 0.45-40 ms Nd:YAG laser: 0.5-40 ms Maximum pulse energy PDL: 12 J Nd:YAG laser: 30 J Method of optical output Lens-coupled optical fiber with user-selectable spot sizes Networking method Dimensions (H x W x D) Weight Electrical requirements Wi-Fi 53 x 20 x 33 in / 135 x 51 x 84 cm 280 lbs / 127 kg 220-240 VAC, 24 A max, 50/60 Hz, single phase Cooling methods Patented Dynamic Cooling Device (DCD) and EverCool contact cooling Patented Dynamic Cooling Device (DCD) Integrated controls, cryogen container, and handpiece with distance gauge Cryogen DCD spray duration HFC 134a User-adjustable range: 20-100 ms DCD delay duration User-adjustable range: 10-100 ms DCD post-spray duration User-adjustable range: 0-50 ms Beam spot sizes 3-15 mm Zoom handpiece 3 x 10 mm Patented EverCool contact cooling User-controlled, adjustable sapphire cooling tip for use pre, during, and post pulse Temperature range Beam spot size 10 C-20 C 3-15 mm Zoom handpiece For more information about how Vbeam Prima* may help you achieve your practice goals, visit syneron-candela.com 1. Vbeam 510(k) clearance (K033461), January 2004. 2. Vbeam 510(k) clearance for pigmented lesion handpiece accessory (K051359), July 2005. 3. Bernstein EF, Kligman A. Rosacea treatment using the newgeneration, high-energy, 595 nm, long pulse-duration pulsed-dye laser. Lasers Surg Med. 2008;40(4):233-239. 4. Woo SH, Ahn HH, Kim SN, Kye YC. Treatment of vascular skin lesions with the variable-pulse 595 nm pulsed dye laser. Dermatol Surg. 2006;32(1):41-48. 5. Chapas AM, Eickhorst K, Geronemus RG. Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Lasers Surg Med. 2007;39(7):563-568. 6. Jasim ZF, Woo WK, Handley JM. Long-pulsed (6-ms) pulsed dye laser treatment of rosacea-associated telangiectasia using subpurpuric clinical threshold. Dermatol Surg. 2004;30(1):37-40. 7. Jørgensen GF, Hedelund L, Hædersdal M. Long-pulsed dye laser versus intense pulsed light for photodamaged skin: a randomized split-face trial with blinded response evaluation. Lasers Surg Med. 2008;40(5):293-299. 8. Halachmi S, Israeli H, Ben-Amitai D, Lapidoth M. Treatment of the skin manifestations of hereditary hemorrhagic telangiectasia with pulsed dye laser. Lasers Med Sci. 2014;29(1):321-324. 9. Yu W, Ma G, Qiu Y, et al. Prospective comparison treatment of 595-nm pulsed-dye lasers for virgin port-wine stain. Br J Dermatol. 2015;172(3):684-691. 10. Galeckas KJ, Ross EV, Uebelhoer NS. A pulsed dye laser with a 10-mm beam diameter and a pigmented lesion window for purpura-free photorejuvenation. Dermatol Surg. 2007;34:1-6. 11. Madan V, Ferguson J. Using the ultra-long pulse width pulsed dye laser and elliptical spot to treat resistant nasal telangiectasia. Lasers Med Sci. 2010;25(1):151-154. 12. Indications for 1064 nm wavelength. Candela, data on file. 13. Bernstein EF. The pulsed-dye laser for treatment of cutaneous conditions. G Ital Dermatol Venereol. 2009;144(5):557-572. 14. Ross EV. Vbeam Prima before and after photos. Candela, data on file. 15. National Rosacea Society website. https://www.rosacea.org/weblog/415- million-people-affected-rosacea-worldwide. Accessed May 8, 2018. 16. Consumer rosacea laser attitude and behavior exploratory: final report. September 7, 2017. BuzzBack Market Research. 17. Bernstein EF, Schomacker K, Paranjape A, Jones CJ. Pulsed dye laser treatment of rosacea using a novel 15 mm spot size. Candela, data on file. 2019 Candela Corporation. This material contains registered trademarks, trade-names and brand names of Candela Corporation and its affiliates, including Syneron, Candela, DCD, Dynamic Cooling Device, EverCool, ScleroPlus, Vbeam, and Vbeam Perfecta. All other trademarks are the property of their respective owners. All rights reserved. PB98812EN R14