LARS (Ligament Augmentation & Reconstruction System) Literature

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LARS-Related Studies and Papers ACL: 1. Level of Evidence: IV Li, H. et al (2011). Enhancement of the osseointegration of a polyethylene Terephthalate artificial ligament graft in a bone tunnel using 58S bioglass. Int. Orthop, February. [Epub ahead of print] 2. Level of Evidence: IV Li, H. et al (2010). Hydroxyapatite coating enhances polyethylene teraphelate artificial ligament graft osseointegration in the bone tunnel. Int. Orthop, November. [Epub ahead of print] 3. Level of Evidence: V* Machotka, S. et al. (2010). Anterior Cruciate Ligament repair with LARS (Ligament Advanced Reinforcement System): A Systematic Review.. Sports Med Arthrosc Rehabil Ther Technol. 2010 Dec 7;2(1):29. [Epub ahead of print] 4. Level of Evidence: III* Hamido, F. et al. (2010). The use of the LARS artificial ligament to augment a short or undersized ACL hamstrings tendon graft. The Knee, November. [Epub ahead of print] 5. Level of Evidence: IV* Gao, K. et al. (2010). Anterior Cruciate Ligament Reconstruction With LARS Artificial Ligament: A Multicenter Study With 3- to 5-Year Follow-up. Arthroscopy. The Journal of Arthroscopic and Related Surgery, Vol 26, No 4 (April), 2010: pp 515-523 6. Level of Evidence: IV* Huang, J. et al. (2010). Cruciate ligament reconstruction using LARS artificial ligament under arthroscopy: 81 cases report. Chin Med J 2010;123(2):160-164 7. Level of Evidence: III* Zhong-tang Liu et al. (2009). Four-strand hamstring tendon autograft versus LARS artificial ligament for anterior cruciate ligament reconstruction. International Orthopedics, 2009 Apr 25. [Epub ahead of print] 8. Level of Evidence: IV* Yu, S.B. et al. (2008). Histological characteristics an ultrastructure of polyethylene terephthalate LARS ligament following the reconstruction of anterior cruciate ligament in rabbits. Zhongguo Zuzhi Gongcheng Yanjiu yu Linchuang Kangfu 2008;12(36):7061-7066 9. Level of Evidence: III* Fan, Q. et al. (2008). Comparison between four-strand semitendinosus tendon autograft and ligament advanced reinforcement system for anterior cruciate ligament reconstruction by arthroscopy. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2008 Jun;22(6):676-9.

LARS-Related Studies and Papers ACL: 10. Level of Evidence: IV* Cerulli, G. et al. (2007). ACL reconstruction using artificial ligaments: Five years follow-up. S.I.O.T, 33 (3suppl. 1), pp. 8238-8242 11. Level of Evidence: IV* Trieb, K. et al. (2004). In vivo and in vitro cellular ingrowth into a new generation of artificial ligament. Eur Surg Res. May-Jun;36(3):148-51. 12. Level of Evidence: I* Nau, T. et al. (2002). A new generation of artificial ligaments in reconstruction of the anterior cruciate ligament. Blinded prospective randomised study. JBJS (Br), Vol 84b (3), pp. 356-360 13. Level of Evidence: IV* Lavoie, P. et al. (2000). Patient satisfaction needs as related to knee stability and objective findings after ACL reconstruction using LARS artificial ligament. The Knee, 7, pp. 157-163 14. Level of Evidence: V* Derricks, G. (1995). LARS anterior cruciate ligament reconstruction, Operative Techniques in Sports Medicine, 3(3): 187-205. LARS-Related Studies and Papers PCL: 15. Level of Evidence: IV* Shen, G. et al.(2010). Arthroscopic Posterior Cruciate Ligament Reconstruction Using LARS Artificial Ligament: A Retrospective Study. J Surg Res. 2010 Sep 8. [Epub ahead of print] 16. Level of Evidence: III* Li, P et al. (2008). Arthroscopic single-bundle posterior cruciate ligament reconstruction: retrospective review of hamstring tendon graft versus LARS artificial ligament. International Orthopedics, Jul: 25, 17. Level of Evidence: IV* Xu, Y. et al. (2008). [A clinical report on arthroscopic reconstruction of posterior cruciate ligament using ligament advanced reinforcement system]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2008 Oct;22(10):1184-8.

LARS-Related Studies and Papers PCL: 18. Level of Evidence: IV* Brunet, P. et al. (2005). [Reconstruction of acute posterior cruciate ligament tears using a synthetic ligament]. Rev Chir Orthop Reparatrice Appar Mot, 2005; 91(1):34-43 19. Level of Evidence: V* Teule, P. et al. (2000). Posterior Cruciate Ligament Reconstruction: The Role of Synthetic Ligaments. Riv Lt Biol Med 20. 20. Level of Evidence: V* Laboureau, J.P (2001). Reconstruction of posterior cruciate ligament rupture and posterolateral instability with synthetic ligaments. Editions Scientifiques et Medicales Elsevier SAS (Paris). Surgical Techniques in Orthopaedics and Traumatology, 2001: 55-540-C-20. LARS-Related Studies and Papers Hip: 21. Level of Evidence: IV* Holroyd, B. et al. (2009). Synthetic Ligaments in Hip Surgery. European Musculoskeletal Review pp. 52-54 22. Level of Evidence: IV* Holroyd, B. et al. (2008). A Novel use for Synthetic Ligaments in Hip Surgery. Annals Royal Collage of Surgery.90: pp. 253-259. LARS-Related Studies and Papers Multi-Ligament: 23. Level of Evidence: IV* Ranger, P. et al. (2010). Evaluation of reconstructive surgery using artificial ligaments in 71 acute knee dislocations. Int Orthop. 2010 Nov 24. [Epub ahead of print]. 24. Level of Evidence: IV* Ibrahin, S.A. et al. (2008). Surgical management of traumatic knee dislocation. Arthroscopy 24(2), pp.178-187. 25. Level of Evidence: IV* Dominikus, M. et al. (2006). Reconstructing the Extensor Apparatus with a New Polyester Ligament. Clinical Orthopaedics and Related Research, 453, pp. 328 334

LARS-Related Studies and Papers Multi-Ligament: 26. Level of Evidence: IV* Talbot, M. et al. (2004). Knee dislocations: Experience at the Hôpital du Sacré-Coeur de Montréal. Can J Surg. 2004 Feb;47(1):20-4. LARS-Related Studies and Papers Patellar Tendon: 27. Level of Evidence: IV* Naim, S. et al (2011). Patellar tendon reconstruction using LARS ligament: surgical technique and case report. Strategies Trauma Limb Reconstr. 2011 Apr;6(1):39-41. Epub 2011 Jan 14. LARS-Related Studies and Papers Foot & Ankle: 28. Level of Evidence: IV* Dhillon MS, et al. (2010). Reconstruction of bilateral spontaneous chronic idiopathic Achilles tendon rupture using LARS ligament: Case report. Foot (Edinb). 2010 Oct 21. [Epub ahead of print] 29. Level of Evidence: IV* Ibrahin, S.A. et al. (2009). Surgical treatment of Chronic Achilles Tendon Rupture. The Journal of Foot and Ankle Surgery 49(3), pp. 340-347. LARS-Related Studies and Papers Rotator Cuff 30. Level of Evidence: IV* Krenn, M. et al. (2005). Permanent tendon replacement for RC defect. Nonsense, alternative or a solution? 33 patients, 2 months 3.5 years, average age 57.6. Jatros Orthopedics 2005, pp. 11 13

LARS-Related Studies and Papers AC Joint 31. Level of Evidence: III* Fraschini G, et al. (2010). Surgical treatment of chronic acromioclavicular dislocation: Comparison between two surgical procedures for anatomic reconstruction. Injury. [Epub ahead of print] 32. Level of Evidence: III* Fialka, C. et al. (2005). Biomechanical Analysis of Different Operative Techniques with complete ACJ disruption. Osteo Trauma Care, pp. 154-159. 33. Level of Evidence: V* Fialka, C. et al. (2004). Traumatic ACJ separation. Current concept. European Surgery Journal, 20(24). LARS-Related Studies and Papers Bio-mechanics: 34. Level of Evidence: IV* Hagemeister, N. et al (2003). Computer based method for the three-dimensional kinematic analysis of combined posterior cruciate ligament and postero-lateral complex reconstructions on cadaver knees, The Knee, 10(3): 249-256. 35. Level of Evidence: IV* Hagemeister, N. et al (2002). Quantitative comparison of three different types of anterior cruciate ligament reconstruction methods: Laxity and 3-D kinematic measurements, Bio-Medical Materials and Engineering, 12(1): 47-57. 36. Level of Evidence: IV* Hagemeister, N. et al (2002). Comparison of two methods for reconstruction of the posterior cruciate ligament using a computer based method: quantitative evaluation of laxity, threedimensional kinematics and ligament deformation measurement in cadaver knees, The Knee, 9(4): 291-299. 37. Level of Evidence: IV* Hagemeister, N. et al (2003). Computer based method for the three-dimensional kinematic analysis of combined posterior cruciate ligament and postero-lateral complex reconstructions on cadaver knees, The Knee, 10(3): 249-256.

LARS-Related Studies and Papers Bio-mechanics: 38. Level of Evidence: IV* Sati, M. et al. (1996). Improving in vivo knee kinematic measurements: application to prosthetic ligament analysis, The Knee, 3(4): 179-190. Expert Reviews on Synthetic Ligaments: 39. Level of Evidence: V* Legnani, C. et al. (2010). Anterior cruciate ligament reconstruction with synthetic grafts. A review of literature. Int Orthop. 2010 Apr;34(4):465-71. 40. Level of Evidence: V* Bernardino, S. (2010). ACL prosthesis: any promise for the future? Knee Surg Sports Traumatol Arthrosc. 2010 Jun;18(6):797-804 41. Level of Evidence: V* Chen, J. et al. (2009). Scaffolds for tendon and ligament repair: review of the efficacy of commercial products. Expert Rev Med Devices. 2010 Jan;7(1):9. 42. Level of Evidence: V* Mascarenhas, R et al. (2008): Anterior cruciate ligament reconstruction: a look at prosthetics - past, present and possible future. Mcgill J Med. 2008 Jan;11(1):29-37.

Level of Evidence I* 1 Level of Evidence II*: 0 Level of Evidence III*: 6 Level of Evidence IV*: 26 Level of Evidence V*: 5 In Total 41 *Levels of Evidence for Primary Research Question correspond to the actual guidelines of the Journal of Bone and Joint Surgery Available on: http://www2.ejbjs.org/misc/instrux.dtl Updated on: Updated August 27, 2010