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Purpose: To establish guidelines for Childhood Preventive Care Screening.To specify and define the Alliance guidelines for periodic health screening and preventive health services for members up to 21 years old provided by primary care providers. Policy: The Alliance uses the current American Academy of Pediatrics (AAP) Recommendations for Preventive Pediatric Health Care, as well as the current ACIP/AAP immunization schedule, in formulating plan specific standards and guidelines. Since all Alliance primary care providers who care for Medi-Cal children are expected to be enrolled as CHDP providers, all other CHDP policies related to the provision of pediatric preventive services are applicable as well. A. The following standards and guidelines address periodic health screening and preventive services for low risk, asymptomatic children and adolescents. Individuals identified as being at high risk for a given condition may require screening at intervals that are more frequent or the performance of additional screening tests specific to the condition. Highrisk individuals are defined as those individuals whose risk behaviors, family history, socioeconomic status, ethnic background, or life style is associated with a higher tendency towards a specific disease. B. PCPs who provide periodic health screening to members under the age of 21 years old must adhere to the periodicity and content of the current AAP Periodicity Schedule for Health Assessment Requirements by Age Groups, as included in attachment 1. C. In addition to the content of the AAP guidelines, certain CHDP required interventions must be provided as well. At each periodic health-screening visit, these include: a. Comprehensive health and developmental history, including assessment of both physical and mental health development. b. Assessment of nutritional status and screening for obesity. c. Dental screening, including inspection of the mouth, teeth, and gums. PCPs must refer children to a dentist annually, starting at age three. d. Tobacco smoking history or exposure: 1. Exposure to passive (second-hand) smoke. 2. Tobacco used by patient. 3. Counseled regarding, or referred, for tobacco use prevention or cessation. D. PCPs must endeavor to complete an Initial Health Assessment (IHA) within 120 days Page 1 of 4

of assignment to the practice for Alliance Medi-Cal members unless it has been determined by the PCP practice that the member s medical records contain complete and current information consistent with the health assessment criteria stated above. An IHA consists of a comprehensive history, physical and mental status examination, an Individual Health Education Behavioral Assessment (IHEBA), identified diagnosis and plan of care. It is strongly encouraged that non- Medi-Cal members have a visit with their PCP within a similar time frame. The Alliance ensures that all new Members complete the IHEBA within 120 calendar days of enrollment as part of the IHA and that all existing members complete the IHEBA at their next non-acute care visit, but no later than their next scheduled screening exam E. Immunizations must be provided according to the current schedule of the Advisory Committee on Immunization Practices (ACIP), AAP, and the American Academy of Family Physicians (AAFP.) PCPs are expected to administer medically necessary immunizations in the PCP s office. When immunizations are provided at sites other than the PCP s office, the provider should notify the PCP s office of the immunization given and the date. a. If this is not possible, the member or parent/guardian of the member must be advised to provide this information to the PCP at the next visit. b. PCP office should be requesting previous medical record(s) to show a complete history. F. Unless the member has received a periodic health screening (well visit) within the periodicity schedule, in attachment 1, the member, or the member s parent/guardian, must be informed at the time of each non-emergency primary care visit of the availability of well visits available through the PCP s practice, or at another site offering well visits. a. Should the member not receive periodic health screening services according to the attached schedule, either: 1. The voluntary refusal of the member (or the parent/guardian) regarding the use of well visits should be documented in the member s medical record, or: 2. There should be documentation of an outbound phone call or written communication from the provider to the member advising of the need to schedule a periodic health screening appointment. b. In the case where a child scheduled for a periodic health screening visit is not seen as scheduled, the PCP s staff should contact the member (or parent/guardian) to reschedule the visit, and document same in the medical record (see Alliance Policy 401-1509 Missed Appointments and Patient Recall). Page 2 of 4

G. Appointments: Where a request is made for children s preventative services by the member, the member s parent(s) or guardian, or through the referral from the local CHDP Program, an appointment shall be made for the Member to be examined within two (2) weeks of the request. H. Diagnosis and treatment of any medical conditions identified through the periodic health screening process, either by the PCP or through referral to a specialist, must be initiated within 60 days of identification. Justification for delays beyond 60 days are to be entered into the member s medical record. For Medi-Cal members, a CHDP PM160 form must be completed at each well visit in addition to documentation of the visit findings in the medical record. a. For CHDP clients, a copy of the PM 160 form is to be given to the member or parent/guardian after completion of the visit. Upon request by the member, or the parent/guardian of the member, the PCP must provide additional discussion or consultation regarding the results of the health assessment. b. The Alliance submits completed forms (PM-160) to DHCS and to the local children s preventative services program within 30 calendar days of the end of each month for all encounters during that month. I. Parents of children found to have conditions which could constitute eligibility for the California Children s Services (CCS) Program should be so informed. The PCP s staff should initiate a referral to the county CCS office, regarding the finding of a potentially eligible child. J. Documentation of Women, Infant and Children Program (WIC) referral or participation must be made for all eligible children (i.e. children under the age of five years) at the initial IHA and at subsequent well visits. K. Monitoring and Quality Management a. Reports of encounter data will be reviewed periodically by the Alliance Quality Management staff for appropriateness and timeliness of child and adolescent preventive care services. b. As a component of the ongoing audit of medical records in each PCP s practice, documentation of children s preventive services will be reviewed periodically. L. The Alliance shall provide information to all network providers regarding the Vaccines for Children (VFC) Program Page 3 of 4

Definitions: Procedures: (See Attached AAP Guidelines for Current Year) References: Alliance Policies: 401-1512 - Missed Appointments and Patient Recall Regulatory: Contractual: DHCS Medi-Cal Contract Exhibit A, Attachment 10, Section 4 Legislative: MMCD Policy Letter: Lines of Business This Policy Applies To: Medi-Cal Healthy Families Healthy Kids Santa Cruz Healthy Kids Merced Alliance Care IHSS Access for Infants and Mothers Individual Conversion Santa Cruz County LIHP Program Monterey County LIHP Program Merced County LIHP Program Revision History: Review Date Revised Date Changes Made By Approved By 11/012002 11/012002 Barbara Palla, MD Quality Management Committee 01/01/2004 01/01/2004 Barbara Palla, MD Quality Management Committee 04/01/2007 04/01/2007 Barbara Flynn, RN Quality Management Committee 04/01/2008 04/01/2008 Barbara Flynn, RN CQIC 04/01/2009 04/01/2009 Barbara Flynn, RN CQIC 08/01/2010 08/01/2010 Andres Aguirre CQIC 09/01/2011 09/01/2011 Patricia Smith, RN Barbara Flynn, RN, 02/24/2012 02/24/2012 Kaite McGrew Barbara Flynn, RN Page 4 of 4

FIGURE 1: Recommended immunization schedule for persons aged 0 through 6 years United States, 2012 (for those who fall behind or start late, see the catch-up schedule [Figure 3]) Vaccine Age Birth 1 month 2 4 6 Hepatitis B 1 Hep B HepB Rotavirus 2 RV RV RV 2 Diphtheria, tetanus, pertussis 3 DTaP DTaP DTaP Haemophilus influenzae type b 4 Hib Hib Hib 4 Pneumococcal 5 PCV PCV PCV Inactivated poliovirus 6 IPV IPV Influenza 7 Measles, mumps, rubella 8 Varicella 9 Hepatitis A 10 Meningococcal 11 This schedule includes recommendations in effect as of December 23, 2011. Any dose not administered at the age should be administered at a subsequent visit, when indicated and feasible. The use of a combination vaccine generally is preferred over separate injections of its equivalent component vaccines. Vaccination providers should consult the relevant Advisory Committee on Immunization Practices (ACIP) statement for detailed recommendations, available online at http://www.cdc.gov/vaccines/pubs/acip-list.htm. Clinically significant adverse events that follow vaccination should be reported to the Vaccine Adverse Event Reporting System (VAERS) online (http://www.vaers.hhs.gov) or by telephone (800-822-7967). 1. Hepatitis B (HepB) vaccine. (Minimum age: birth) At birth: Administer monovalent HepB vaccine to all newborns before hospital discharge. For infants born to hepatitis B surface antigen (HBsAg) positive mothers, administer HepB vaccine and 0.5 ml of hepatitis B immune globulin (HBIG) within 12 hours of birth. These infants should be tested for HBsAg and antibody to HBsAg (anti-hbs) 1 to 2 after completion of at least 3 doses of the HepB series, at age 9 through 18 (generally at the next well-child visit). If mother s HBsAg status is unknown, within 12 hours of birth administer HepB vaccine for infants weighing 2,000 grams, and HepB vaccine plus HBIG for infants weighing <2,000 grams. Determine mother s HBsAg status as soon as possible and, if she is HBsAg-positive, administer HBIG for infants weighing 2,000 grams (no later than age 1 week). Doses after the birth dose: The second dose should be administered at age 1 to 2. Monovalent HepB vaccine should be used for doses administered before age 6 weeks. Administration of a total of 4 doses of HepB vaccine is permissible when a combination vaccine containing HepB is administered after the birth dose. Infants who did not receive a birth dose should receive 3 doses of a HepBcontaining vaccine starting as soon as feasible (Figure 3). The minimum interval between dose 1 and dose 2 is, and between dose 2 and 3 is 8 weeks. The final (third or fourth) dose in the HepB vaccine series should be administered no earlier than age 2 and at least 16 weeks after the first dose. 2. Rotavirus (RV) vaccines. (Minimum age: 6 weeks for both RV-1 [Rotarix] and RV-5 [Rota Teq]) The maximum age for the first dose in the series is 1, 6 days; and 8, 0 days for the final dose in the series. Vaccination should not be initiated for infants aged 15 weeks, 0 days or older. If RV-1 (Rotarix) is administered at ages 2 and 4, a dose at 6 is not indicated. 3. Diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine. (Minimum age: 6 weeks) The fourth dose may be administered as early as age 12, provided at least 6 have elapsed since the third dose. 4. Haemophilus influenzae type b (Hib) conjugate vaccine. (Minimum age: 6 weeks) If PRP-OMP (PedvaxHIB or Comvax [HepB-Hib]) is administered at ages 2 and 4, a dose at age 6 is not indicated. Hiberix should only be used for the booster (final) dose in children aged 12 through 4 years. 5. Pneumococcal vaccines. (Minimum age: 6 weeks for pneumococcal conjugate vaccine [PCV]; 2 years for pneumococcal polysaccharide vaccine [PPSV]) Administer 1 dose of PCV to all healthy children aged 24 through 59 who are not completely vaccinated for their age. For children who have received an age-appropriate series of 7-valent PCV (PCV7), a single supplemental dose of 13-valent PCV (PCV13) is for: All children aged 14 through 59 Children aged 60 through 71 with underlying medical conditions. Administer PPSV at least 8 weeks after last dose of PCV to children aged 2 years or older with certain underlying medical conditions, including a cochlear implant. See MMWR 2010:59(No. RR-11), available at http://www.cdc.gov/ mmwr/pdf/rr/rr5911.pdf. 6. Inactivated poliovirus vaccine (IPV). (Minimum age: 6 weeks) If 4 or more doses are administered before age 4 years, an additional dose should be administered at age 4 through 6 years. The final dose in the series should be administered on or after the fourth birthday and at least 6 after the previous dose. 9 12 HepB see footnote 3 IPV Hib PCV 15 DTaP 18 Influenza (Yearly) 19 23 Dose 1 10 MCV4 see footnote 11 2 3 years PPSV 4 6 years DTaP 7. Influenza vaccines. (Minimum age: 6 for trivalent inactivated influenza vaccine [TIV]; 2 years for live, attenuated influenza vaccine [LAIV]) For most healthy children aged 2 years and older, either LAIV or TIV may be used. However, LAIV should not be administered to some children, including 1) children with asthma, 2) children 2 through 4 years who had wheezing in the past 12, or 3) children who have any other underlying medical conditions that predispose them to influenza complications. For all other contraindications to use of LAIV, see MMWR 2010;59(No. RR-8), available at http://www.cdc.gov/mmwr/pdf/rr/rr5908.pdf. For children aged 6 through 8 years: For the 2011 12 season, administer 2 doses (separated by at least ) to those who did not receive at least 1 dose of the 2010 11 vaccine. Those who received at least 1 dose of the 2010 11 vaccine require 1 dose for the 2011 12 season. For the 2012 13 season, follow dosing guidelines in the 2012 ACIP influenza vaccine recommendations. 8. Measles, mumps, and rubella (MMR) vaccine. (Minimum age: 12 ) The second dose may be administered before age 4 years, provided at least have elapsed since the first dose. Administer MMR vaccine to infants aged 6 through 11 who are traveling internationally. These children should be revaccinated with 2 doses of MMR vaccine, the first at ages 12 through 15 and at least after the previous dose, and the second at ages 4 through 6 years. 9. Varicella (VAR) vaccine. (Minimum age: 12 ) The second dose may be administered before age 4 years, provided at least 3 have elapsed since the first dose. For children aged 12 through 12 years, the minimum interval between doses is 3. However, if the second dose was administered at least after the first dose, it can be accepted as valid. 10. Hepatitis A (HepA) vaccine. (Minimum age: 12 ) Administer the second (final) dose 6 to18 after the first. Unvaccinated children 24 and older at high risk should be vaccinated. See MMWR 2006;55(No. RR-7), available at http://www.cdc.gov/ mmwr/pdf/rr/rr5507.pdf. A 2-dose HepA vaccine series is for anyone aged 24 and older, previously unvaccinated, for whom immunity against hepatitis A virus infection is desired. 11. Meningococcal conjugate vaccines, quadrivalent (MCV4). (Minimum age: 9 for Menactra [MCV4-D], 2 years for Menveo [MCV4-CRM]) For children aged 9 through 23 1) with persistent complement component deficiency; 2) who are residents of or travelers to countries with hyperendemic or epidemic disease; or 3) who are present during outbreaks caused by a vaccine serogroup, administer 2 primary doses of MCV4-D, ideally at ages 9 and 12 or at least 8 weeks apart. For children aged 24 and older with 1) persistent complement component deficiency who have not been previously vaccinated; or 2) anatomic/functional asplenia, administer 2 primary doses of either MCV4 at least 8 weeks apart. For children with anatomic/functional asplenia, if MCV4-D (Menactra) is used, administer at a minimum age of 2 years and at least after completion of all PCV doses. See MMWR 2011;60:72 6, available at http://www.cdc.gov/mmwr/pdf/wk/ mm6003. pdf, and Vaccines for Children Program resolution No. 6/11-1, available at http://www. cdc.gov/vaccines/programs/vfc/downloads/ resolutions/06-11mening-mcv.pdf, and MMWR 2011;60:1391 2, available at http://www.cdc.gov/mmwr/pdf/wk/mm6040. pdf, for further guidance, including revaccination guidelines. IPV MMR see footnote 8 MMR Varicella see footnote 9 Varicella This schedule is approved by the Advisory Committee on Immunization Practices (http://www.cdc.gov/vaccines/recs/acip), the American Academy of Pediatrics (http://www.aap.org), and the American Academy of Family Physicians (http://www.aafp.org). Department of Health and Human Services Centers for Disease Control and Prevention HepA Series ages for all children ages for certain high-risk groups ages for all children and certain highrisk groups

FIGURE 2: Recommended immunization schedule for persons aged 7 through 18 years United States, 2012 (for those who fall behind or start late, see the schedule below and the catch-up schedule [Figure 3]) Vaccine Age 7 10 years 11 12 years 13 18 years Tetanus, diphtheria, pertussis 1 Human papillomavirus 2 Meningococcal 3 Influenza 4 Pneumococcal 5 Hepatitis A 6 Hepatitis B 7 Inactivated poliovirus 8 Measles, mumps, rubella 9 Varicella 10 This schedule includes recommendations in effect as of December 23, 2011. Any dose not administered at the age should be administered at a subsequent visit, when indicated and feasible. The use of a combination vaccine generally is preferred over separate injections of its equivalent component vaccines. Vaccination providers should consult the relevant Advisory Committee on Immunization Practices (ACIP) statement for detailed recommendations, available online at http://www.cdc.gov/vaccines/ pubs/acip-list.htm. Clinically significant adverse events that follow vaccination should be reported to the Vaccine Adverse Event Reporting System (VAERS) online (http://www. vaers.hhs.gov) or by telephone (800-822-7967). 1. Tetanus and diphtheria toxoids and acellular pertussis (Tdap) vaccine. (Minimum age: 10 years for Boostrix and 11 years for Adacel) Persons aged 11 through 18 years who have not received Tdap vaccine should receive a dose followed by tetanus and diphtheria toxoids (Td) booster doses every 10 years thereafter. Tdap vaccine should be substituted for a single dose of Td in the catchup series for children aged 7 through 10 years. Refer to the catch-up schedule if additional doses of tetanus and diphtheria toxoid containing vaccine are needed. Tdap vaccine can be administered regardless of the interval since the last tetanus and diphtheria toxoid containing vaccine. 2. Human papillomavirus (HPV) vaccines (HPV4 [Gardasil] and HPV2 [Cervarix]). (Minimum age: 9 years) Either HPV4 or HPV2 is in a 3-dose series for females aged 11 or 12 years. HPV4 is in a 3-dose series for males aged 11 or 12 years. The vaccine series can be started beginning at age 9 years. Administer the second dose 1 to 2 after the first dose and the third dose 6 after the first dose (at least 2 after the first dose). See MMWR 2010;59:626 32, available at http://www.cdc.gov/mmwr/pdf/ wk/mm5920.pdf. 3. Meningococcal conjugate vaccines, quadrivalent (MCV4). Administer MCV4 at age 11 through 12 years with a booster dose at age 16 years. Administer MCV4 at age 13 through 18 years if patient is not previously vaccinated. If the first dose is administered at age 13 through 15 years, a booster dose should be administered at age 16 through 18 years with a minimum interval of at least 8 weeks after the preceding dose. If the first dose is administered at age 16 years or older, a booster dose is not needed. Administer 2 primary doses at least 8 weeks apart to previously unvaccinated persons with persistent complement component deficiency or anatomic/functional asplenia, and 1 dose every 5 years thereafter. Adolescents aged 11 through 18 years with human immunodeficiency virus (HIV) infection should receive a 2-dose primary series of MCV4, at least 8 weeks apart. See MMWR 2011;60:72 76, available at http://www.cdc.gov/mmwr/ pdf/wk/mm6003.pdf, and Vaccines for Children Program resolution No. 6/11-1, available at http://www.cdc.gov/vaccines/programs/vfc/downloads/ resolutions/06-11mening-mcv.pdf, for further guidelines. 4. Influenza vaccines (trivalent inactivated influenza vaccine [TIV] and live, attenuated influenza vaccine [LAIV]). For most healthy, nonpregnant persons, either LAIV or TIV may be used, except LAIV should not be used for some persons, including those with asthma or any other underlying medical conditions that predispose them to influenza complications. For all other contraindications to use of LAIV, see MMWR 2010;59(No.RR-8), available at http://www.cdc.gov/mmwr/ pdf/rr/rr5908.pdf. Administer 1 dose to persons aged 9 years and older. 1 dose (if indicated) 1 dose 1 dose (if indicated) see footnote 2 3 doses Complete 3-dose series See footnote 3 Dose 1 Booster at 16 years old Influenza (yearly) See footnote 5 Complete 2-dose series Complete 3-dose series Complete 3-dose series Complete 2-Dose 2-dose series Series Complete 2-dose series ages for all children ages for catch-up immunization ages for certain high-risk groups For children aged 6 through 8 years: For the 2011 12 season, administer 2 doses (separated by at least ) to those who did not receive at least 1 dose of the 2010 11 vaccine. Those who received at least 1 dose of the 2010 11 vaccine require 1 dose for the 2011 12 season. For the 2012 13 season, follow dosing guidelines in the 2012 ACIP influenza vaccine recommendations. 5. Pneumococcal vaccines (pneumococcal conjugate vaccine [PCV] and pneumococcal polysaccharide vaccine [PPSV]). A single dose of PCV may be administered to children aged 6 through 18 years who have anatomic/functional asplenia, HIV infection or other immunocompromising condition, cochlear implant, or cerebral spinal fluid leak. See MMWR 2010:59(No. RR-11), available at http://www.cdc.gov/ mmwr/pdf/rr/rr5911.pdf. Administer PPSV at least 8 weeks after the last dose of PCV to children aged 2 years or older with certain underlying medical conditions, including a cochlear implant. A single revaccination should be administered after 5 years to children with anatomic/functional asplenia or an immunocompromising condition. 6. Hepatitis A (HepA) vaccine. HepA vaccine is for children older than 23 who live in areas where vaccination programs target older children, who are at increased risk for infection, or for whom immunity against hepatitis A virus infection is desired. See MMWR 2006;55(No. RR-7), available at http:// www.cdc.gov/mmwr/pdf/rr/rr5507.pdf. Administer 2 doses at least 6 apart to unvaccinated persons. 7. Hepatitis B (HepB) vaccine. Administer the 3-dose series to those not previously vaccinated. For those with incomplete vaccination, follow the catch-up recommendations (Figure 3). A 2-dose series (doses separated by at least 4 ) of adult formulation Recombivax HB is licensed for use in children aged 11 through 15 years. 8. Inactivated poliovirus vaccine (IPV). The final dose in the series should be administered at least 6 after the previous dose. If both OPV and IPV were administered as part of a series, a total of 4 doses should be administered, regardless of the child s current age. IPV is not routinely for U.S. residents aged18 years or older. 9. Measles, mumps, and rubella (MMR) vaccine. The minimum interval between the 2 doses of MMR vaccine is. 10. Varicella (VAR) vaccine. For persons without evidence of immunity (see MMWR 2007;56[No. RR- 4], available at http://www.cdc.gov/mmwr/pdf/rr/rr5604.pdf), administer 2 doses if not previously vaccinated or the second dose if only 1 dose has been administered. For persons aged 7 through 12 years, the minimum interval between doses is 3. However, if the second dose was administered at least after the first dose, it can be accepted as valid. For persons aged 13 years and older, the minimum interval between doses is. This schedule is approved by the Advisory Committee on Immunization Practices (http://www.cdc.gov/vaccines/recs/acip), the American Academy of Pediatrics (http://www.aap.org), and the American Academy of Family Physicians (http://www.aafp.org). Department of Health and Human Services Centers for Disease Control and Prevention

FIGURE 3. Catch-up immunization schedule for persons aged 4 through 18 years who start late or who are more than 1 month behind United States 2012 The figure below provides catch-up schedules and minimum intervals between doses for children whose vaccinations have been delayed. A vaccine series does not need to be restarted, regardless of the time that has elapsed between doses. Use the section appropriate for the child s age. Always use this table in conjunction with the accompanying childhood and adolescent immunization schedules (Figures 1 and 2) and their respective footnotes. Vaccine Minimum Age for Dose 1 Hepatitis B Birth Persons aged 4 through 6 years Minimum Interval Between Doses Dose 1 to dose 2 Dose 2 to dose 3 Dose 3 to dose 4 Dose 4 to dose 5 8 weeks and at least 16 weeks after first dose; minimum age for the final dose is 2 Rotavirus 1 6 weeks 1 Diphtheria, tetanus, pertussis 2 6 weeks 6 6 2 Haemophilus influenzae type b 3 6 weeks if first dose administered at younger than age 12 8 weeks (as final dose) if first dose administered at age 12 14 if first dose administered at age 15 or older 3 if current age is younger than 12 8 weeks (as final dose) 3 if current age is 12 or older and first dose administered at younger than age 12 and second dose administered at younger than 15 if previous dose administered at age 15 or older 8 weeks (as final dose) This dose only necessary for children aged 12 through 59 who received 3 doses before age 12 Pneumococcal 4 6 weeks if first dose administered at younger than age 12 8 weeks (as final dose for healthy children) if first dose administered at age 12 or older or current age 24 through 59 for healthy children if first dose administered at age 24 or older if current age is younger than 12 8 weeks (as final dose for healthy children) if current age is 12 or older for healthy children if previous dose administered at age 24 or older 8 weeks (as final dose) This dose only necessary for children aged 12 through 59 who received 3 doses before age 12 or for children at high risk who received 3 doses at any age Inactivated poliovirus 5 6 weeks 6 5 minimum age 4 years for final dose Meningococcal 6 9 8 weeks 6 Measles, mumps, rubella 7 12 Varicella 8 12 3 Hepatitis A 12 6 Tetanus, diphtheria/ tetanus, diphtheria, pertussis 9 7 years 9 Persons aged 7 through 18 years if first dose administered at younger than age 12 6 if first dose administered at 12 or older 6 if first dose administered at younger than age 12 Human papillomavirus 10 9 years Routine dosing intervals are 10 Hepatitis A 12 6 Hepatitis B Birth 8 weeks (and at least 16 weeks after first dose) Inactivated poliovirus 5 6 weeks 5 6 5 Meningococcal 6 9 8 weeks 6 Measles, mumps, rubella 7 12 Varicella 8 12 3 if person is younger than age 13 years if person is aged 13 years or older 1. Rotavirus (RV) vaccines (RV-1 [Rotarix] and RV-5 [Rota Teq]). The maximum age for the first dose in the series is 1, 6 days; and 8, 0 days for the final dose in the series. Vaccination should not be initiated for infants aged 15 weeks, 0 days or older. If RV-1 was administered for the first and second doses, a third dose is not indicated. 2. Diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine. The fifth dose is not necessary if the fourth dose was administered at age 4 years or older. 3. Haemophilus influenzae type b (Hib) conjugate vaccine. Hib vaccine should be considered for unvaccinated persons aged 5 years or older who have sickle cell disease, leukemia, human immunodeficiency virus (HIV) infection, or anatomic/functional asplenia. If the first 2 doses were PRP-OMP (PedvaxHIB or Comvax) and were administered at age 11 or younger, the third (and final) dose should be administered at age 12 through 15 and at least 8 weeks after the second dose. If the first dose was administered at age 7 through 11, administer the second dose at least later and a final dose at age 12 through 15. 4. Pneumococcal vaccines. (Minimum age: 6 weeks for pneumococcal conjugate vaccine [PCV]; 2 years for pneumococcal polysaccharide vaccine [PPSV]) For children aged 24 through 71 with underlying medical conditions, administer 1 dose of PCV if 3 doses of PCV were received previously, or administer 2 doses of PCV at least 8 weeks apart if fewer than 3 doses of PCV were received previously. A single dose of PCV may be administered to certain children aged 6 through 18 years with underlying medical conditions. See age-specific schedules for details. Administer PPSV to children aged 2 years or older with certain underlying medical conditions. See MMWR 2010:59(No. RR-11), available at http:// www.cdc.gov/mmwr/pdf/rr/rr5911.pdf. 5. Inactivated poliovirus vaccine (IPV). A fourth dose is not necessary if the third dose was administered at age 4 years or older and at least 6 after the previous dose. In the first 6 of life, minimum age and minimum intervals are only if the person is at risk for imminent exposure to circulating poliovirus (i.e., travel to a polio-endemic region or during an outbreak). IPV is not routinely for U.S. residents aged 18 years or older. 6. Meningococcal conjugate vaccines, quadrivalent (MCV4). (Minimum age: 9 for Menactra [MCV4-D]; 2 years for Menveo [MCV4-CRM]) See Figure 1 ( Recommended immunization schedule for persons aged 0 through 6 years ) and Figure 2 ( Recommended immunization schedule for persons aged 7 through 18 years ) for further guidance. 7. Measles, mumps, and rubella (MMR) vaccine. Administer the second dose routinely at age 4 through 6 years. 8. Varicella (VAR) vaccine. Administer the second dose routinely at age 4 through 6 years. If the second dose was administered at least after the first dose, it can be accepted as valid. 9. Tetanus and diphtheria toxoids (Td) and tetanus and diphtheria toxoids and acellular pertussis (Tdap) vaccines. For children aged 7 through 10 years who are not fully immunized with the childhood DTaP vaccine series, Tdap vaccine should be substituted for a single dose of Td vaccine in the catch-up series; if additional doses are needed, use Td vaccine. For these children, an adolescent Tdap vaccine dose should not be given. An inadvertent dose of DTaP vaccine administered to children aged 7 through 10 years can count as part of the catch-up series. This dose can count as the adolescent Tdap dose, or the child can later receive a Tdap booster dose at age 11 12 years. 10. Human papillomavirus (HPV) vaccines (HPV4 [Gardasil] and HPV2 [Cervarix]). Administer the vaccine series to females (either HPV2 or HPV4) and males (HPV4) at age 13 through 18 years if patient is not previously vaccinated. Use routine dosing intervals for vaccine series catch-up; see Figure 2 ( Recommended immunization schedule for persons aged 7 through 18 years ). Clinically significant adverse events that follow vaccination should be reported to the Vaccine Adverse Event Reporting System (VAERS) online (http://www.vaers.hhs.gov) or by telephone (800-822-7967). Suspected cases of vaccine-preventable diseases should be reported to the state or local health department. Additional information, including precautions and contraindications for vaccination, is available from CDC online (http://www.cdc.gov/vaccines) or by telephone (800-CDC-INFO [800-232-4636]).