BIMOXYL LA A LONG ACTING AMOXYCILLIN INJECTABLE SUSPENSION Abbey Animal Health Pty Ltd Material Safety Data Sheet Section 1- Identification of Product and Supplier Supplier Company Details: Abbey Animal Health Pty Ltd Address: 165 Sharp ST, Cooma NSW 2630 Telephone Number: 02 8090 7187 Facsimile Number: 02 9475 0775 Emergency Number: Australian Poisons Information Centre: 13 11 26 (24 Hour service). Product Name: BIMOXYL LA A LONG ACTING AMOXYCILLIN INJECTABLE SUSPENSION Other Names: None allocated Appearance: A cream to off-white suspension. Use: Veterinary antibiotic for the treatment of bacterial infections sensitive to amoxycillin in cattle, sheep, pigs, dogs and cats. Section 2- Hazards Identification STATEMENT OF HAZARDOUS NATURE: Non-hazardous substance, non-dangerous goods according to criteria of NOHSC* Australia and ADG** Code. Poison Schedule: S4. Potential Acute Health Effects: Human: The active ingredient is potentially hazardous to penicillin and cephalosporin sensitive individuals. Allergic reaction to these substances may occasionally be serious. Slightly hazardous in case of skin contact (irritant), eye contact (irritant), ingestion, and inhalation. Glass vials may explode at high temperature. Environment: Non hazardous *NOHSC = National Occupational Health and Safety Commission. **ADG= Australian Dangerous Goods code. First Effective Date: 1 st of Nov. 2013 Page 1 of 6
Section 3- Composition / Information on Ingredients INGREDIENTS: Chemical Name CAS No. Content Amoxycillin Trihydrate 61336-70-7 150mg/mL Section 4- First Aid Measures Eyes: Holding eyelids apart, wash immediately with plenty of eyewash solution or clean water for at least 15 minutes. Seek medical advice. Skin: Using gloves, remove contaminated clothing. Wash off immediately with soap and water. Obtain medical attention in cases of persistent irritation. Ingestion: If swallowed, obtain immediate medical attention. Do not induce vomiting unless directed by medical personnel. Rinse mouth thoroughly with water. Inhalation: Remove patient to fresh air. Medical Information: This product may cause hypersensitivity reaction in susceptible individuals. Hypersensitivity to penicillins may lead to cross reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious. If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this Material Safety Data Sheet. Swelling of the face, lips, eyes or difficulty breathing are more serious symptoms and require urgent medical attention. For advice contact Veterinarian or the Poisons information Centre (Phone 13 11 26). Section 5- Fire Fighting Measures Extinguishing Media: Foam. Fire and Explosion Hazards: Due to oil content, the product supports combustion at high temperatures. Glass vials may explode at high temperature. Protective Measures and Equipment: Wear self-contained breathing apparatus and appropriate protective clothing. First Effective Date: 1 st of Nov. 2013 Page 2 of 6
Section 6 - Accidental Release Measures Personal Precautions: For large spillages, evacuate area. Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves. For small spillages absorb with cloth or suitable absorbent and dispose of as contaminated waste. Prevent skin contact. May cause hypersensitivity reaction in susceptible individuals. Environmental Precautions: Spillages or uncontrolled discharges into watercourses drains or sewers must be immediately alerted to the Environment Agency or other applicable regulatory body. Methods for clean-up/recovery: Soak up with inert absorbent. Transfer to a double polyethylene-lined container for disposal. Wash spill site and ventilate area after material pickup is complete. The spillage area should be washed with detergent and water. Section 7 - Handling and Storage Handling: Do not eat or drink when using. Wash hands after handling material. Avoid contact with eyes or skin. The product is contained in glass vials, handle with care. Storage: Store only in the original container at room temperature (not exceeding 25 C). Protect from light. Keep out of reach and sight of children. Specific use: Use only for the intended purpose. Section 8 - Exposure Controls / Personal Protection Occupational Precautions: No hazard under normal conditions of use. Avoid exposure to the product. Practice normal good hygiene. Do not handle this product if you have been advised not to work with penicillins or cephalosporins. Engineering Measures: Avoid unnecessary exposure to the product. Personal Protective Equipment: Avoid contact with skin. Wear suitable rubber or PVC gloves and suitable protective clothing. Respiratory: Not required under normal conditions of use. Hand: Chemical protective gloves. Wash hands after use. Eye: Avoid contact with the eyes. Occupational exposure limits: No information available. First Effective Date: 1 st of Nov. 2013 Page 3 of 6
Section 9 - Physical and Chemical Properties Appearance: A cream to off-white suspension. Physical state: Suspension for injection. Odour: Odourless. ph: Not determined. Boiling Point: No information available. Flash Point: No information available. Flammability / Autoflammability: No information available. Explosive Properties: Glass vials may explode at high temperature. Oxidizing Properties: No information available. Vapour Pressure: No information available. Solubility in Water/Fat: No information available. Section 10 - Stability and Reactivity Stability: Stable for three years from the date of manufacture when stored unopened below 25 C. Any product remaining later than 28 days following the date of first broaching the seal should be discarded. Conditions to Avoid: Protect from light, including direct sun rays. Glass vials may explode at high temperatures. Materials to Avoid: None known. Hazardous Decomposition Products: May emit noxious to toxic fumes if heated to decomposition. Section 11 - Toxicological Information ALWAYS READ AND FOLLOW THE LABEL INSTRUCTIONS AND WARNINGS Potential Acute Health Affects: Inhalation: Not applicable. Skin Contact: Amoxycillin trihydrate acute subcutaneous LD50 >8 g/kg (Rat), LD50 >20 g/kg (mouse). Acute intraperitoneal LD50 >2870 g/kg (Rat), LD50 >3590 g/kg (mouse). Eye Contact: Not determined. Ingestion: Amoxycillin trihydrate acute oral LD50 >15 g/kg (Rat), LD50 >25 g/kg (mouse), LD50 >12.5 g/kg (rabbit). Acute oral TDLo = 2800 mg/kg (rat), 9100 mg/kg (mouse). Carcinogenicity: Not reported. Chronic: Not reported. First Effective Date: 1 st of Nov. 2013 Page 4 of 6
Section 12 - Ecological Information Mobility: No information available. Persistence and Degradability: Amoxycillin is readily biodegradable. Bioaccumulative potential: No information available Aquatic toxicity: No information available. Other: In normal use, the environmental impact of this product is considered to be low. Section 13 - Disposal Considerations Product: Small amounts of product may be disposed of by flushing away with plenty of water. Contact your local office of the Environment Agency or a licensed waste disposal contractor for advice on disposal of large amounts of unused material, spillage or waste contaminated with this product. Containers: Used containers should be flushed out with plenty of water and disposed of in domestic waste, taking care to avoid spillage or leakage. Dispose of empty container by wrapping with paper and putting in garbage. For large quantities dispose via an authorised disposal contractor. UN Number None allocated Section 14 - Transport Information UN Number: None allocated Proper Shipping Name: None allocated Dangerous Goods Class and Subsidiary Risk: None allocated Transport Classification: Not classified as dangerous for transport. Packaging Group Number: None allocated Packaging (Size & Description): 100ml clear glass vials sealed with plain aluminium caps. Special Storage Precautions for User: Store below 25 C (Air Conditioning). Protect from light. Hazchem Code: None allocated. Section 15 - Regulatory Information BIMOXYL LA A LONG ACTING AMOXYCILLIN INJECTABLE SUSPENSION is classified as S4 according to the Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP). APVMA Approval No. 47146. Approved pack sizes: 100mL and 250mL. First Effective Date: 1 st of Nov. 2013 Page 5 of 6
Section 16 Other Information For additional information contact: Abbey Animal Health Pty Ltd Telephone Number: 02 8090 7187 Facsimile Number: 02 9475 0775 Emergency Number: Australian Poisons Information Centre: 13 11 26 (24 Hour service). This Material Safety Data Sheet (MSDS) summarises our best knowledge of the health and safety hazard information of the product and how to safely handle and use the product in the workplace. Each user must review this MSDS in the context of how the product will be handled and used in the workplace. If clarification or further information is needed to ensure that an appropriate risk assessment can be made, the user should contact this company. First Effective Date: 1 st of Nov. 2013 Page 6 of 6