Advantages of MISS. Disclosures. Thoracolumbar Trauma: Minimally Invasive Techniques. Minimal Invasive Spine Surgery 11/8/2013.

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3 rd Annual UCSF Techniques in Complex Spine Surgery Program Thoracolumbar Trauma: Minimally Invasive Techniques Research Support: Stryker Disclosures Murat Pekmezci, MD Assistant Clinical Professor UCSF/SFGH Orthopedic Trauma Institute Minimal Invasive Spine Surgery Advantages of MISS Smaller incisions/minimal soft tissue disruption Improved healing and decreased infection risk Less blood loss 1

Advantages of MISS Trauma Perspective: Ability to perform surgery in Silver day Mobilize the patient decreased risk of ARDS, Head injury Disadvantages of MISS Learning Curve Accuracy Long term outcomes (pain, etc) Need for hardware removal??? T-L reductions difficult Thoracolumbar Trauma: Minimally Invasive Techniques Posterior Techniques Posterior Percutaneous posterior segmental instrumentation Anterior Balloon-assisted reduction Endoscopic assisted approaches Mini Open Anterior Approach Percutaneous posterior segmental fixation Temporizing Measure Damage Control Definitive Care 2

New Strategy for T-L Trauma Temporizing Measure Polytrauma patient with spine fracture - Too sick. Damage Control maintaining a ship s functions while it has taken on damage Trauma/General surgery to quickly stop bleeding and surgically resuscitate a patient Damage Control Spine Surgery Damage Control Spine Surgery Trauma patients are often too sick for the BIG spine procedure Percutaneous posterior spinal fixation Retrospective review of 10 patients with > 24 month f/u MISS within 48 hrs No revision surgery except planned hardware removal Blood loss avg 177 ml Surgery time 95 min Poelstra et al, 2009 AAOS Annual Meeting, Las Vegas, NV 3

SFGH Data Oct 2008-24 patients (age, 17-80) Average level of instrumentation 3.8 (2-10) Mean OR Time: 173 min (66-360) Mean EBL: 180cc (50-500) Complication: Superficial infection (1), DVT (1), PE (1) Case Example X-ray Indirect Reduction 4

New Strategy for T-L Trauma Definitive Fixation Isolated unstable spine fracture - Is there a less invasive technique. 5

52 y/o female s/p 2 story fall sustaining an unstable T10 fracture, rib fractures and SAH Screw and Rod Placement Percutaneous Pedicle Screw Instrumentation for Temporary Internal Bracing of Nondisplaced Bony Chance Fractures 2 cases L2 and L4 (neuro intact) Short-segment pedicle screw construct for Chance fractures J Spinal Disorders and Techniques, May 2007 6

Technique Technique Technique 7

Technique Technique Technique Technique 8

Technique Technique Technique Accuracy & Reduction 9

SFGH Data Patients who had percutaneous instrumentation and postoperative CT scan Accuracy evaluated by Neuro-radiologist, Ortho-spine surgeon Neuro-spine surgeon Accuracy with C-Arm Criteria developed by Gertzbein et al. A: lateral pedicle wall penetration B: superior or inferior pedicle wall penetration C: medial pedicle wall penetration D: anterolateral vertebral body penetration Quantitative grade 1: >0 and _2 mm 2: >2 and _4 mm 3: >4 mm 4: >4 mm w/o pedicle or vertebral body contact Sixteen patients 102 screws Accuracy with C-Arm Posterior Techniques NeuroRad Ortho-Spine Neuro-Spine No Breach 90.2 99.1 94 100 57 98.1 Lateral Breach 2.0 1.0 19.6 Sup-Inf Breach 0 0 2.9 Medial Breach 1.0 2.0 27.4 Anterior Breach 6.9 4.9 10.7 Percutaneous posterior segmental fixation Temporizing Measure Damage Control Definitive Care 10

Indications for Anterior Approach Decompress neural elements Anterior Approach Anterior column support Load Sharing Classification Anterior Techniques Sixty-two patients General satisfaction (82%) Postoperative pain (32.3%), Bulging (43.5%), Functional disturbance (24.2%) Balloon-assisted reduction Endoscopic assisted approaches Mini Open Anterior Approach 11

Balloon Assisted Reduction and Augmentation with Calcium Phosphate Cement Balloon Assisted Reduction and Augmentation with Calcium Phosphate Cement Preservation of motion segments (short segment posterior fusion) Avoids morbidity of anterior approach Less blood loss Lower infection rate Less pain / improved recovery time Technique: Open or Percutaneous +/- Posterior Fixation Short segment fixation with cement augmentation of burst fractures 28 patients A3 burst injury / 13 with incomplete deficit Balloon assisted reduction with Norian Ca Phosphate cement 22 (79 %) laminectomy Operative time 116 min (80-165) Blood loss 316 (50-1200) 80yo F s/p syncopal fall with back pain December 28, 2009 PMH: HTN, hyperlipidemia, asthma Physical Exam: 5/5 strength in BUE, BLE, intact rectal tone Thoracolumbar Burst Fractures Treated with Posterior Decompression and Pedicle Screw Instrumentation Supplemented with Balloon-Assisted Vertebroplasty and Calcium Phosphate Reconstruction JBJS 2009 12

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Thoracoscopic-assisted treatment of thoracic and lumbar fractures 373 pts (T3-L3) Supplemental posterior instrumentation 65% Complication rate 1.3% Steep learning curve Neurosurgery. 2002 Nov;51(5 Suppl):S104-17. Thoracoscopic transdiaphragmatic approach to thoracolumbar junction fractures 212 patients Supplemental posterior fixation 64.6% Complication rate 11.7% Conversion to open 1.4% Spine J. 2004 May-Jun;4(3):317-28 MISS Techniques for Anterior Column Reconstruction Advantages of MOA Mini Open Technique Reduced pain Better cosmesis Excellent direct visualization No approach surgeon 14

46 y/o F with L1 burst Positioning C-arm localization 15

Retractor Placement Cage Placement Post op X-rays 16

SFGH Data SFGH Data 17

SFGH Data SFGH Data Clinical Outcomes ODI 17.6 ± 12.1 SF 12 PCS 45.0% ± 6.70% SF 12 MCS 54.4% ± 9.68% Cage Subsidence Subsidence remains a problem Robertson et al, 2004 7% Uchida et al, 2006 17% Blattert et al, 2008 12% 18

56 y/o female, fall from 3 rd floor Novel Footplate Design 19

27 y/o female, 4 story fall Footplate Design and Resistance to Subsidence Pekmezci et al BIOMECHANICS Figure 3. The ultimate load and stiffness results for the 3 test groups. Error bars represent the 95% confi dence intervals of the mean. between 0 and 3 mm of ad and slightly increased nt. displacement curve, along ultimate load showed dif- corpectomy defect, the goal is to implant the largest footplate suitable. The higher contact area results in a lower force per unit area, which in turn should lead to lower subsidence DISCUSSION rate. Reinhold et al 9 recently confi rmed that bigger endplate Expandable cages are frequently used in the reconstruction of defects after thoracolumbar corpectomy; however, subsidence surface areas are associated with higher resistance to subsidence. Although an increase in the surface area with a larger remains a problem. Subsidence of expandable cages depends on several variables, including bone quality, fi t on the end- footplate will decrease the force per unit area, circular cages 20

Lumbopelvic Dissociation 21

Lumbopelvic Dissociation 22

26 yo M Thank You 23