Atherosclerotic Heart Disease: Coronary Vessels, EKG Localization of STEMI and Complications/Derivatives for USMLE Step One

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Atherosclerotic Heart Disease: Coronary Vessels, EKG Localization of STEMI and Complications/Derivatives for USMLE Step One Howard J. Sachs, MD Associate Professor of Medicine University of Massachusetts Medical School www.12daysinmarch.com E-mail: Howard@12daysinmarch.com

They will never ask you to name a vessel Name this vessel

They will never ask you to name a vessel They will ask you the manifestations of that blocked vessel.

They will ask you the manifestations of that blocked vessel. Well, they won t actually say manifestations of a blocked vessel. They ll say chest pain and ST segment (elevation/depression) in leads

CT Angiogram, Coronary Vessels Blood in LV

CT Angiogram, Coronary Vessels Left Main

CT Angiogram, Coronary Vessels Ramus Intermedius (left main trifurcation)

Lateral Wall by LCX Anterior Wall by LAD Inferior Wall by RCA

Lateral Wall by LCX Anterior Wall by LAD Posterior Wall by RCA

RCA LCX LAD Lateral Wall by LCX Anterior Wall by LAD Inferior Wall by RCA

RCA R C A P D A S e p LAD t LAD u Anterior m Wall by LAD 1/3 2/3 LCX Lateral Wall by LCX Inferior Wall by RCA

II III avf III II avf

II III avf

II III avf

II III avf

II III avf Reciprocal Changes: If the inferior wall has ST elevations, the anterior (contralateral leads) wall will have ST depressions (opposite vectors)

Reciprocal Changes Present in Ischemia/Infarction II III avf Acute Pericarditis: diffuse (inferior, anterior and lateral) ST-segment elevation devoid of reciprocal changes

Patient experiences STEMI 3 days ago. Now with sharp chest pain relieved while leaning forward. VSS; lungs clear; cor scratchy heart sound. Choose the correct diagnosis?: A. Acute pericarditis B. Extension of myocardial infarction

II III avf Derivatives: RCA occlusion/imi (inferior wall MI)

RCA occlusion (IMI) Bradyarrhythmias Sinus Bradycardia 2 nd Degree Heart Block

RCA occlusion (IMI) Bradyarrhythmias Sinus Bradycardia 2 nd Degree Heart Block Patient with chest pain and elevated troponin. Rhythm strip shown. Occlusion of which vessel is most likely? EKG will show elevations in which leads?

RCA occlusion (IMI) Bradyarrhythmias Sinus Bradycardia 2 nd Degree Heart Block Patient with chest pain and elevated troponin. Rhythm strip shown. Occlusion of which vessel is most likely RCA (or PDA) EKG will show elevations in which leads II, III, avf

RCA Posterior Descending Artery Dominance (or Co-dominance) ~80% ~10%

RCA PDA Dominance (Posterior 1/3 Septum) ~80% ~10%

RV Infarct Left Ventricle: EF? PCWP? Lung exam?

RV Infarct Left Ventricle: EF: normal PCWP: normal Lung exam: clear

JVP Q. Patient with cardiogenic shock and normal EF/PCWP with clear lungs RV Infarct

RCA RV infarct Hypotension Elevated CVP Clear lungs High index of suspicion Very pre-load dependent: push fluids, avoid nitrates Right sided chest leads

Coronary Vessels, EKG Localization of STEMI and Derivatives for USMLE Step One Right Coronary Artery [inferior (posterior) wall] Leads: II, III, avf Sinoatrial and AV Nodes bradyarrhythmia Dominance: supplies the posterior descending a. Posterior 1/3 of septum RV infarct: cardiogenic shock without LV EDV Left Circumflex (lateral wall) Leads: I, avl, V5,6 Dominance Territorial pattern Left Anterior Descending Leads: V2,3,4 Major MI, Major Complications (for the boards) Rupture: LV free wall tamponade; Papillary muscle mitral regurgitation, CHF Cardiogenic shock Special Notes: Reciprocal changes

LCX Lateral Wall I, avl, V5, 6

LCx I, avl, V5, 6 Lateral Wall

Take homes for Left Circumflex: 1. Dominance: infrequent; if dominant, supplies PDA (and posterior 1/3 septum) 2. Territorial pattern: overall pattern of elevations in acute pericarditis

Take homes for Left Circumflex: 1. Dominance: infrequent; if dominant, supplies PDA (and posterior 1/3 septum) 2. Territorial pattern: overall pattern of elevations in acute pericarditis Acute Pericarditis

Take homes for Left Circumflex: 1. Dominance: infrequent; if dominant, supplies PDA (and posterior 1/3 septum) 2. Territorial pattern: overall pattern of elevations in acute pericarditis 3. Occlusion: lateral wall infarction

Anterior Wall, LAD V2-4

Anterior Wall, LAD V2-4

Look at limb leads for reciprocal s in AWMI Anterior Wall, LAD V2-4

Anterior Wall Infarction (STEMI) LAD, V2-4

Key Derivatives: Anterior Wall Infarction (STEMI) LAD, V2-4 LV Free Wall Rupture Macrophage Phase Papillary Muscle

Key Derivatives: Anterior Wall Infarction (STEMI) LAD, V2-4 Macrophage Phase Day 5 post-awmi Cardiogenic Shock Hemopericardium Pulsus Paradoxus

Key Derivatives: Anterior Wall Infarction (STEMI) LAD, V2-4 Day 5 post-awmi New Onset CHF M Harsh, holosystolic axilla Macrophage Phase

Key Derivatives: Anterior Wall Infarction (STEMI) LAD, V2-4 Cardiogenic Shock

Key Derivatives: Anterior Wall Infarction (STEMI) LAD, V2-4 LV Aneurysm

Key Derivatives: Anterior Wall Infarction (STEMI) LAD, V2-4 Mural Thrombus LV Aneurysm

RCA LCX LAD Lateral Wall by LCX Anterior Wall by LAD Inferior Wall by RCA

RCA LCX LAD Lateral Wall by LCX Anterior Wall by LAD Inferior Wall by RCA

Coronary Vessels, EKG Localization of STEMI and Derivatives for USMLE Step One Right Coronary Artery [inferior (posterior) wall] Leads: II, III, avf Sinoatrial and AV Nodes bradyarrhythmia Dominance: supplies the posterior descending a. Posterior 1/3 of septum RV infarct: cardiogenic shock without LV EDV Left Circumflex (lateral wall) Leads: I, avl, V5,6 Dominance Territorial pattern Left Anterior Descending Leads: V2,3,4 Major MI, Major Complications (for the boards) Rupture: LV free wall tamponade; Papillary muscle mitral regurgitation, CHF Cardiogenic shock LV aneurysm and sequelae Special Notes: Reciprocal changes and acute pericarditis

Atherosclerotic Heart Disease: Coronary Vessels, EKG Localization of STEMI and Complications/Derivatives for USMLE Step One Howard J. Sachs, MD Associate Professor of Medicine University of Massachusetts Medical School www.12daysinmarch.com E-mail: Howard@12daysinmarch.com