Research as part of a clinical career

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Research as part of a clinical career Dr Alison Tree Consultant Clinical Oncologist, Royal Marsden Hospital Associate Honorary Faculty, Institute of Cancer Research

2 Firstly This has been a really hard talk to write! Why would you want to pursue an academic career within the NHS? What are the benefits and drawbacks of this approach? Tips (from the top) for success Thanks to Peter Hoskin, Chris Nutting, Chris Parker, Charlotte Coles, Nick van As, Fiona McDonald, Anna Kirby, Katharine Aitken, Corinne Faivre-Finn

3 My (current) perspective MD(Res) at the ICR, on SBRT 2011-2014 Consultant at the Royal Marsden 2014- present Expectation but no dedicated time for research Wrote grants, papers, started up projects 1 PA of my time funded via a PCUK clinical trial grant 2 PAs of my time funded via a Rosetrees grant, supporting MR Linac research

4 What are we talking about? Those who are research active but are employed by the NHS May have an honorary affiliation with a university too May or may not have official time to do research Only really relevant to non-laboratory research i.e. clinical research with patients

5 What you need to make it as a clinical academic A strong constitution A dislike for sleep The ability to work harder than you thought possible

6 What is the hardest work I have ever done? Junior doctor? Nope (56 hours on call) Having 3 babies in just over 5 years? Nope Trying to pursue an academic career whilst an NHS consultant?

7 Why do it at all then??!?? Median survival 45 to 60 months James et al, Lancet 2015

8 The Pro s of staying within the NHS Job security No shortage of patients to recruit to clinical trials Able to determine your own research priorities (nobody telling you what to research) Academic clinical oncology jobs are like hen s teeth Copyright Dreamworks/ Aardman animations

9 The Con s of staying within the NHS as a consultant Hard/Impossible to get protected research time (patients come first) = not enough sleep/time with family Lack of infrastructure and support for research eg admin support, finance support Some grants (eg MRC) mandate a University lead No road map to progression Credit: Calvin and Hobbs

10 Vast majority of radiotherapy research is done within a clinical setting This requires Machines Radiographers Hospital infrastructure support Those within the NHS are somewhat better placed to influence the research infrastructure within the Hospitals where the research is done.

11 16 tips from others how to pursue an academic clinical oncology career within the NHS 1. Start as a trainee publish something (anything!) to get started 2. Get a research degree MD/PhD (alison.tree@icr.ac.uk), usually years 4-5 3. The main thing is to make the main thing the main thing Stephen Covey say no to other things (even good things) 4. Find a department with supportive colleagues who will cover for you and be prepared to cover them

12 16 tips from others how to pursue an academic clinical oncology career within the NHS 5. Have some research momentum to take into your consultant job. Helpful to have some research under your belt and ideas that you want to pursue 6. Be collegiate recruit to other people s trials. It s a small world. 7. Come up with a trial idea and take it to CTRad supportive peer input, get to know other research-active clin oncs in the UK

CTRad Aims: To proactively identify, nurture and advise young investigators in radiotherapy research To support trial design, methodology, protocol development, and quality assurance To ensure that all trials involving radiotherapy are efficient and technologically up-to-date To provide specialist review of radiotherapy trial proposals for CRUK Slide credit Chris Nutting

14 Some tips from others how to pursue an academic clinical oncology career within the NHS 8. Get involved with patient groups go an give a talk, ask them to review your patient information sheet. Listen to what they say. 9. Find a good clinical trials and statistics unit and find every excuse to hang around them. Listen this stuff sounds tedious at first but is CRITICAL to the success of your future studies. 10. Think about the biology - imaging and laboratory endpoints: Add the extra value translation! 11. Look ahead for deadlines: Conference abstracts / funding applications to ensure local timelines for co-investigators realistic with everyone under pressure.

15 Some tips from others how to pursue an academic clinical oncology career within the NHS 12. Solve service pressures yourself business cases 13. Get a grant and put 1-2 PAs of your time on it 14. Or negotiate a feasible job plan from the start 15. Work in a research active institution (hard to do in a vacumn) 16. Find a mentor (or two), or a buddy, and ask for help Copyright RusTempo.ru

16 The supportive UK academic community

17 Most importantly Find a problem that needs solving Don t try to pursue an academic career find a problem your patients are facing and try to find the answer "We need less research, better research, and research done for the right reasons." Doug Altman (1948-1918)

The wisdom of Twitter

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20 Where to go for more information Academy of Medical Sciences https://acmedsci.ac.uk/grants-and-schemes/grant-schemes/csf MRC NIHR CRUK Site specific charities PCUK, Breast Cancer Now