Neuro-Audio Version 2010

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ABR PTA ASSR Multi-ASSR OAE TEOAE DPOAE SOAE ECochG MLR P300 Neuro-Audio Version 2010 one device for all audiological tests Auditory brainstem response (ABR)/Brainstem evoked response audiometry (BERA) (air and bone conduction) including EABR Auditory steady-state response (ASSR) with possibility of simultaneous stimulation at 4 frequencies for both ears (multi-assr) Transient evoked otoacoustic emission (TEOAE) Distortion product otoacoustic emission (DPOAE) Spontaneous otoacoustic emission (SOAE) Middle- and long-latency auditory evoked potentials (MLR, LLR/CAEP) Pure tone audiometry (PTA) (air and bone conduction) Electrocochleography (ECochG) Cognitive evoked potentials (MMN, P300) Medical Diagnostic Equipment Development and Manufacture

Neuro-Audio (Version 2010) Features One Device for All Audiological Tests Most of the tests needed for your daily audiological practice are in just one box with the size of a small book, powered from a personal computer. This Neuro-Audio (version 2010) device has: One USB cable to connect device to a computer 2 DIN connectors Set of sockets on side bottom panel to connect all LED impedance indicator and stimulators: headphones, insert earphones, OAE probe Impedance check button and bone vibrator Combined trig-in and trig-out socket (to connect 5 touch-proof connectors to plug electrodes to DIB for cochlear implant, for example) No other devices, cables, batteries, chargers and power supply units needed! LED impedance indicators Impedance check button Operation indicator Touch proof connectors DIN connectors Bone vibrator Headphones OAE probe (Neurosoft Ltd.) OAE probe (Etymotic Research) Many Supported Transducers Neuro-Audio (version 2010) supports many transducers for audiometric tests available on the market. Headphones: TDH-39, HDA-280 High-frequency headphones: HDA-200, ER-2 Insert earphones: EAR-5A, EAR-3A (10, 50, 300 Ohm; automatic 0.9 ms acoustic delay correction) Bone vibrator B-71 OAE probes: Neurosoft probe, ER-10D probe Loudspeakers for sound-field testing (must be individually calibrated) Some of supported transducers

Simple and Fast Workflow Neuro-Audio.NET software provides a simple workflow to perform tests. Step 1. Enter patient s information to the database Step 2. Select from the list what test you want to do Step 3. Press "Run" button and test is performed automatically Step 4. Once a test is done, software tries to arrange the markers automatically, however, you can correct them manually. Immediately you see all related graphs and tables. If reference values are set for this test, you see all figures compared with reference numbers Step 5. Press "Report" button and report is generated in editable format (Microsoft Word) Step 1. Enter patient s information Unlimited Flexibility When the software is installed, all tests are preset for daily practice. And you do not need to make any changes. But when you need it, you can change practically any parameter you wish: parameters of acquisition and stimulation, window layout, colors, report, etc. Step 2. Choose what do you want to do Shortest ABR Acquisition Time Neuro-Audio.NET has several signal processing features which significantly decrease ABR acquisition time: 1. Weighted averaging decreases required quantity of sweeps to get a clear trace 2. Minimize interference feature helps to reduce electrical interference 3. Chirp stimulus activates all cochlear hair cells simultaneously which increases signal amplitude 4. High frequency stimulation. Even at 50 Hz stimulation you still clearly see peak V. But this decreases test duration by up to 5 times comparing with 11 Hz stimulation 5. Statistical algorithms for online objective analysis of waveforms for response presence (Fsp/Fmp) eliminate observer s subjectivity and save valuable test time Step 3. Run the test and observe the process Fast ABR Analysis Step 4. See the result 1. Automatic ABR marker arrangement with possibility of manual correction 2. A/B buffers to check reproducibility quickly 3. Automatically displayed normative data (reference values) based on patient s age 4. Latency/intensity graphs and analysis tables 5. 64-bit data processing on 64-bit computers Step 5. Print the report

Automatic ABR Threshold Search Protocol ABR threshold search is one of the most widespread routine tests in objective audiometry. We developed a special automatic ABR protocol Objective hearing threshold search. In this mode the whole process is done automatically. You need only to prepare a patient, start this protocol and simply observe the procedure, stopping it when you see the threshold. New and Traditional ABR 1. Traditional click ABR 2. Tone burst ABR to estimate frequency-specific hearing thresholds 3. Bone conduction ABR for infants with ear canal atresia or other structural malformations 4. Chirp ABR (wideband, frequency-specific) 5. Electric ABR (EABR) for patients with cochlear implants EABR test Screening Mode for OAE DPOAE and TEOAE tests can be performed in screening mode. In this mode minimum interaction with the machine is needed to perform the test. Software tells you what to do next or does it automatically. The results appear as a simple phrase PASS or REFER. Technician can be easily trained to perform screening tests. 12-point DPOAE mode is available (with frequencies up to 12 khz). Multi-ASSR: State of the Art Implementation Minimization of test duration: stimulation of both ears simultaneously using 4 carrier frequencies (500 Hz, 1 khz, 2 khz and 4 khz) in each ear. Independent intensity control for each of 8 stimuli. Effective stimulus enhancing the response amplitude (exponential modulation, narrow-band chirp) Accurate objective technique of response detection (F-test) Two-channel recording improves the signal-to-noise ratio and reduces test time The same electrode placement as in ABR can be used Automatic conversion of frequency-specific ASSR thresholds to estimated audiogram Weighted averaging (with improved accuracy, reduced test time) Independence from patient s state (2 modulation modes: awake (40 Hz) and asleep (90 Hz)) Modulation mode can be changed during test (if awake patient fell asleep, for example) Monitoring of response amplitude and noise floor per ear and per frequency All ASSR data are displayed on a single screen (including response probability and spectrum) DPOAE test Multi-ASSR test Multi-ASSR: estimated audiogram

Pure Tone Audiometry with up to 16 khz Stimulation Pure tone audiometry test with air and bone conduction can be performed with the same device and in the same software, with the same interface which is used for objective test. You do not need to register or recall your patient when you go to PTA test. You just press New test button. Test can be performed automatically (Hughson-Westlake algorithm), or you can control it manually using hot keys on PC keyboard. Patient responds to the stimulus using a remote button. High-frequency audiometry is supported (up to 16 khz) with these transducers: HDA-200 and ER-2. 16 khz pure tone audiometry And More Traditional single-frequency ASSR MLR, LLR: middle and long-latency evoked potentials You can use calibrated loudspeakers to perform tests in a free sound field MMN and P300 for cognitive function evaluation ECochG: electrocochleography test At the Cutting Edge of Science Access to all amplifier, stimulator and signal processing settings allows you to create your own custom test templates, for all your scientific research needs. And if you feel you miss some flexibility or feature, you can always contact our powerful engineering team directly. We are open to innovations! Traditional single-frequency ASSR P300 test

Delivery Set Electronic unit Holder Auditory stimulator for EP (TDH-39 headphones) OAE probe OAE probe tip 3 pcs. Probe tip extractor Set of ear tips (universal) (4-13 mm diameter) Test cavity Dental floss for probe tip cleaning Cup electrode with cable 5 pcs. Pup-jack linker Electrode adhesive paste (100 g) Abrasive paste for skin preparation (160 g) Neuro-Audio.NET software with ABR, MLR, LLR and OAE modules Technical manual, user manual Variants of Delivery Set Three delivery set variants are available, these are Neuro-Audio (version 2010), Neuro-Audio/OAE (version 2010), Neuro-Audio/ABR (version 2010) Available Techniques Neuro-Audio Neuro-Audio/OAE Neuro-Audio/ABR ABR / BERA MLR, LLR/CAEP TEOAE DPOAE ASSR ECochG Cognitive EP (MMN, P300) PTA + ABR option* + + + OAE option* ASSR option* ECochG option* Cognitive EP option* PTA option* + included in the base delivery set * is supplied optionally by special order March 2012 Since 1992 Neurosoft Ltd. 5, Voronin str., Ivanovo, 153032, Russia P.O. Box 10, Ivanovo, 153000, Russia Phone: +7 (4932) 24-04-34 Fax: +7 (4932) 24-04-35 E-mail: com@neurosoft.ru Internet: www.neurosoft.ru