Harvard Medical School Center for Global Health Delivery Dubai Areas of Focus

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Harvard Medical School Center for Global Health Delivery Dubai Areas of Focus Mohammed Bin Rashid Academic Medical Center Building 14 PO Box 505276 Dubai Healthcare City Dubai United Arab Emirates Tel. +971 4 422 1740 Fax +971 4 422 5814 http://ghd-dubai.hms.harvard.edu Ref:/Pixeladv-PVol. 1 Oct2015 http://ghd-dubai.hms.harvard.edu

AUTHORS Brittany Klooster* and Courtney Yuen** *Boston University **Harvard Medical School, Brigham and Women s Hospital DISCLAIMER HARVARD MEDICAL SCHOOL CENTER FOR GLOBAL HEALTH DELIVERY DUBAI Mohammed Bin Rashid Academic Medical Center Building 14 Dubai Healthcare City Dubai, United Arab Emirates The development and publication of this product were made possible by support from the Dubai Harvard Foundation for Medical Research. The contents of this report are the sole responsibility of its Author and do not necessarily reflect the views of the Dubai Harvard Foundation for Medical Research. Any opinion, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of Harvard Medical School or any organization or agency that provided support for this meeting. Harvard Medical School or its licensors at all times owns and retains all right, title, and interest in and to this products (hereafter referred to as the publication ) including all intellectual property rights therein and thereto. You may use and copy the publication, or portions of the publication, provided that you reproduce all copyright notices, claims, or reservation of rights appearing in the publication, as delivered to you, on all copies made pursuant to this sentence. To the maximum extent permitted under applicable laws, the Author is not liable, under any circumstance or under any theory of law, tort, contract, strict liability or otherwise, for any direct, indirect, special, incidental, consequential, exemplary or punitive damages, or any other injury and/or damage (actual or perceived), including, without limitation, damages based on errors, omissions, or reliance upon, use, or operation of any ideas, instructions, procedures, products, or methods contained in the material included in the publication. By using the publication, you acknowledge and agree to the terms of this notice. By using the publication, you acknowledge that (i) the Author is not guaranteeing the completeness or accuracy of the information contained herein, (ii) the publication does not represent nor comprise all of the data or other information that may be relevant to you, (iii) portions of the publication may be outdated and may have been superseded by subsequent changes in applicable law, regulation, or conditions affecting the treatment of tuberculosis or the delivery of health care generally, and (iv) the Author does not have any duty to update the publication or, if updated, to provide further updated versions of the publication. Additional copies of this publication are available from the Harvard Medical School Center for Global Health Delivery Dubai at PO Box 505276, Dubai, United Arab Emirates; +971 4 422 1742; ghd.dubai@hms.harvard.edu For more information about the Harvard Medical School Center for Global Health Delivery Dubai, visit the home page www.ghd-dubai.hms.harvard.edu Copyright 2015 by the Harvard Medical School Center for Global Health Delivery Dubai. All rights reserved. Printed in Dubai, United Arab Emirates 1

Diabetes and Obesity Diabetes and obesity, once considered diseases solely of high-income settings, are now a global epidemic. DIABETES Type 2 diabetes is caused by an ineffective use of insulin by the body (insulin resistance), and usually requires management with lifelong medication and/or insulin. Diabetes is associated with many other health problems, including cardiovascular disease, blindness, nerve damage, kidney failure, and lower limb amputation. Unfortunately, only half of people who have diabetes are aware that they have the disease. Type 2 diabetes has long been recognized as a chronic disease affecting older populations. However, this disease, which was once known as adult onset diabetes, is now affecting young adults and children. Percent of population with diabetes mellitus in countries of the Center s region Kyrgyzstan Data source: International Diabetes Federation Palestinian Territories Somalia United Arab Emirates In 2014, 9% of the world s population had diabetes, and an estimated 5.1 million deaths were caused by diabetes in 2013. The Middle East/North Africa region has the highest rates of adult diabetes worldwide. is among the countries with the highest diabetes prevalence globally, with diabetes affecting 21% of its population in 2014. Several other countries in the Center's region have concerning rates of diabetes as well: in,,,,, and, diabetes affects at least 15% of the population. In the United Arab Emirates, around 10% of the population, representing over 1 million people, has diabetes. <5% 5 9% 10 14% 15 19% 20% OBESITY Obesity increases a person s risk of hypertension, diabetes, stroke, cancer, and death. The causes of obesity are varied: genetics, diet, community environment and physical activity can all contribute. Globally, around 13% of adults, or more than 600 million people, were obese in 2014. However, over 30% of the adult population is Estimated percent of adults ( 18 years old) who were obese (body mass index 30) in countries of the Center s region in 2014 Somalia Kyrgyzstan United Arab Emirates <10% 10 19% 20 29% %30 Data source: Institute for Health Metrics and Evaluation. No data available for Palestinian Territories. obese in,,,, the United Arab Emirates, and ; this corresponds to over 3 million obese adults in the United Arab Emirates alone. Among countries in the Center s region, the highest rates of child obesity are observed in,, and, where more than 15% of people aged 2 19 are obese. References International Diabetes Federation. IDF Diabetes Atlas, Sixth Edition. 2013. International Diabetes Federation. IDF Diabetes Atlas Map, Update 2014 [Accessed July 30, 2015]. Available from: http://www.idf.org/atlasmap/atlasmap World Health Organization. Diabetes Fact Sheet No. 312 [Accessed July 30, 2015]. Available from: http://www.who.int/mediacentre/factsheets/fs312/en/ Institute for Health Metrics and Evaluation. Obesity patterns (BMI 30) for both sexves children (2-19) [Accessed July 30, 2015]. Available from: http://vizhub.healthdata.org/obesity/. World Health Organization. Obesity and Overweight Fact Sheet No. 311 [Accessed July 30, 2015]. Available from: http://www.who.int/mediacentre/factsheets/fs311/en World Health Organization. Global Health Observatory Data Repository [Accessed July 30, 2015]. Available from: http://apps.who.int/gho/data/node.main.a900c?lang=en 2 AREAS OF FOCUS 3

Infectious Diseases While many infectious disease deserve attention globally, two that are particularly concerning among the countries of the Center s region are tuberculosis and hepatitis C. TUBERCULOSIS Tuberculosis, a disease caused by bacteria and transmitted through the air, kills more people worldwide than any infectious disease other than HIV/AIDS. In 2013, an estimated nine million people became ill with tuberculosis, and 1.5 million people died from tuberculosis. An estimated one million children suffered from the disease, with only a third of them diagnosed. Effective treatment for tuberculosis has existed for decades, but rising levels of drug resistance are making tuberculosis harder and more expensive to treat. Among the countries of the Center s region,,,, the, Somalia, and have the highest incidences rates of tuberculosis, each with more than 200 new cases annually for every 100,000 people in the population. Globally, drug-resistant tuberculosis is a particularly serious problem in Eastern European and Central Asian countries. In, Kyrgyzstan,, and, around 20 30% of new tuberculosis patients have multidrug-resistant tuberculosis, which is resistant to the two most effective anti-tuberculosis medications. Estimated number of tuberculosis cases per 100,000 people in the population in countries of the Center s region in 2013 Palestinian Territories United Arab Emirates Data source: World Health Organization Somalia <20 20 99 100 199 200 299 300 HEPATITIS C The hepatitis C virus attacks the liver and can cause both mild and severe illness. Once infected, some people are able to eliminate the virus without treatment, while others develop chronic infection, which can lead to cirrhosis or liver cancer. Around 130 150 million people worldwide have chronic hepatitis C infection. While treatment for hepatitis C is not always necessary, effective antiviral medication exists. However, for many people, the cost of treatment is currently prohibitive. Estimated prevalence of hepatitis C virus infection in 2005, by geographic region Geographic region High-income Asia Pacific 1.4% Central Asia East Asia South Asia Southeast Asia Central Europe Eastern Europe Western Europe Middle East/North Africa East Sub-Saharan Africa South Sub-Saharan Africa West Sub-Saharan Africa Global,,, Kyrgyzstan,,,,,,,,,,,, Somalia, Countries in the Center s region included in geographic region,,,,,,,,,,, Palestinian Territories,, Saudi Arabia,,,, United Arab Emirates, Globally, around 3% of the population is estimated to be infected with hepatitis C virus. The Middle East/North Africa region and the Central and East Asia regions have higher prevalences of hepatitis C virus infection than other parts of the world. Incomplete information exists on the prevalence of infection in individual countries of the Center s region. Estimated percentage of population with hepatitis C virus infection in 2005 3.8% 3.7% 3.4% 2.0% 2.4% 2.9% 2.4% 3.6% 2.0% 2.1% 2.8% 2.8% Adapted from: Mohd Hanafiah et al. Hepatology, 2013. References World Health Organization. Tuberculosis Fact Sheet No. 104 [Accessed August 16, 2015]. Available at: http://www.who.int/mediacentre/factsheets/fs104/en/ World Health Organization. Global tuberculosis report 2014. Geneva, Switzerland: World Health Organization; 2014. World Health Organization. Media Centre: Hepatitis C Fact sheet No. 164. [Accessed August 16, 2015]. Available at: http://www.who.int/mediacentre/factsheets/fs164/en/ Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology 2013; 57(4):1333-42. 4 AREAS OF FOCUS 5

Mental Health The category of mental disorders encompasses a wide range of conditions, from schizophrenia to autism to eating disorders. Estimating the number of people with mental disorders is difficult since diagnosis is complicated, diagnostic criteria may be different in different countries, and many people with mental disorders never seek treatment for these issues. Limited information exists on the burden of important mental disorders such as schizophrenia and post-traumatic stress disorder in the countries of the Center s region. Estimated number of health professionals in the mental health sector per 100,000 people in the population in 2014 DEPRESSION Depression is the most common mental disorder and a major cause of disability worldwide. Several countries in the Center s region were estimated to have rates of depression that were significantly higher than the global average in 2010. These include:,,,,,,,,,,, the United Arab Emirates, and. EATING DISORDERS Eating disorders such as anorexia nervosa and bulimia nervosa are caused by a complex variety of factors. They are characterized by severe trouble with eating habits and weight regulation, and often accompany other mental disorders. Females are more likely than males to be affected, and adolescents and young women are at highest risk. The number of people, especially women, with eating disorders appears to be increasing in Asia and the Middle East; in a recent survey, eating disordered attitudes were observed in 30 40% of adolescent girls in several major cities in the Middle East. SYSTEM CAPACITY The number of health professionals (e.g., nurses, social workers, psychiatrists) working in the area of mental health is used to estimate a system s capacity to confront, prevent and treat mental disorders. Globally, there are approximately nine mental health professionals for every 100,000 people; however, there is large regional variation, with over 40 mental health professionals for every 100,000 people in Europe, but fewer than 10 mental health professionals for every 100,000 in Africa, the Middle East, and Asia. Not surprisingly, the countries in the Center s region vary greatly in their mental health system capacity. In 2011,,,, and all had more than 50 mental health professionals for every 100,000 people. In contrast,,,,, and had less than one mental health professional for every 100,000 people. The United Arab Emirates had 3.4 mental health professionals for every 100,000 people. Adapted from: World Health Organization, Mental Health Atlas 2014. References Ferrari AJ, Charlson FJ, Norman RE, Patten SB, Freedman G, Christopher JL et al. Burden of depressive disorders by country, sex, age, and year: findings from the Global Burden of Disease Study 2010. PLoS Med 2013; 10(11):e1001547. Pike KM, Hoek HW, Dune PE. Cultural trends and eating disorders. Curr Opin Psychiatry 2014; 27(6):436-42. World Health Organization. Mental Health Atlas 2014. Geneva, Switzerland: World Health Organization; 2015. World Health Organization. Mental Health Atlas 2011country profiles. [Accessed August 3, 2015]. Available at: http://www.who.int/mental_health/evidence/atlas/profiles/en/ 6 AREAS OF FOCUS 7

Access to Surgical Care One method of measuring a country s health system capacity is to examine patients ability to access surgery when they need it. This includes emergency surgeries and operations necessary to treat ongoing or chronic conditions. Access to care is difficult to quantify, as the true number of people who require surgery in a given country is unknown, and the ease with which people are able to access surgical care depends on a variety of factors. However, estimates of the proportion of the population with access to surgical care have been made based on indicators that represent a country s surgical infrastructure, safety of surgical facilities, geographic proximity of patients to surgical facilities, and affordability of surgical procedures. In the United Arab Emirates, roughly three quarters of the population is estimated to have access to surgical care. The Center s region contains countries where over 90% of the population is estimated to have access to surgical care ( and ), as well as countries where less than 10% of the population is estimated to have access (,,,,, Kyrgyzstan,,,,,,,, and ). Percentage of population estimated to have access to surgical care Kyrgyzstan United Arab Emirates <10% 10 49% 50 74% 75 100% Data source: Program in Global Surgery and Social Change Reference Alkire BC, Raykar NP, Shrime MG, Weiser TG, Bickler SW, Rose JA, et al. Global access to surgical care: a modelling study. Lancet Global Health 2015; 3(6):e316-23. Unpublished country-level estimates provided by authors. 8 AREAS OF FOCUS 9