Assessing Opioid Misuse and Overdose Using Prescription Drug Monitoring Programs (PDMP) and Other Data Sources

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Assessing Opioid Misuse and Overdose Using Prescription Drug Monitoring Programs (PDMP) and Other Data Sources NPN Conference Anaheim, CA September 12, 2017

Presentations Overview of SAMHSA s Prevention Portfolio Thomas Clarke Social Science Analyst, SAMHSA/CSAP Prevention Planning Using Prescription Drug Monitoring Programs (PDMP) and Other Data Sources: Lessons Learned Sandeep Kasat, Associate Director of Epidemiology, CAPT Core Alyssa O'Hair, Regional Coordinator, CAPT West Resource Team Using Prescription Monitoring Program and Other Data for Prescription Drug and Opioid Misuse Prevention in Minnesota Elisabeth Atherly, Evaluation Consultant, Alcohol and Drug Abuse Division, Minnesota Department of Human Services Melissa Adolfson, Epidemiologist, EpiMachine, LLC

Overview of SAMHSA s Prevention Portfolio Thomas Clarke Social Science Analyst, SAMHSA/CSAP NPN Conference Anaheim, CA September 12, 2017

Overview of the Center for Substance Abuse Prevention s (CSAP s) Grant Portfolio CSAP currently has four opioid related grant programs: Partnerships for Success Prescription Drug Overdose (Partnership with CDC) State Targeted Response (STR): partnership with Center for Substance Abuse Treatment (CSAT) and Center for Behavioral Health Statistics (CBHSQ) Strategic Prevention Framework - Prescription Drugs (SPF-Rx)

Partnerships for Success Overview: Prevent the onset and reduce the progression of substance abuse, prioritizing underage drinking among people age 12 20, prescription drug misuse and abuse among people age 12 25, or both Reduce substance abuse-related problems Strengthen prevention capacity and infrastructure at the state and community levels Leverage, redirect, and align statewide funding streams and resources for prevention

Partnerships for Success Number of current awards: 69 Anticipated award amount: $318,543 to $1,230,000 per year Length of project: 5 years

Prescription Drug Overdose Overview: Implements overdose death prevention strategies, such as naloxone distribution and the purchase of naloxone for first responders Raises awareness among pharmaceutical and medical communities on the risks of overprescribing

Prescription Drug Overdose Number of awards: 12 Estimated award amount: Up to $1,000,000 per year Length of project period: Up to 5 years

State Targeted Response Overview: Aims to address the opioid crisis by increasing access to treatment, reducing unmet treatment need, and reducing opioid overdose related deaths through the provision of prevention, treatment and recovery activities for opioid use disorder (OUD)

State Targeted Response Total available funding: $485,000,000 per year Number of awards: 59 Length of project: Up to 2 years

SPF Rx Raises awareness of the dangers of sharing medications, and work with pharmaceutical and medical communities on the risks of overprescribing to young adults Implements prescription drug misuse prevention activities and education to schools, communities, parents, prescribers, and their patients

SPF Rx Aims to assist grantees in developing capacity and expertise in the use of data from state-run Prescription Drug Monitoring Programs (PDMPs) SPF Rx builds on the established SPF-based state and tribal prevention infrastructures The focus of SPF Rx is on prescription drug misuse among youth ages 12-17 and adults 18 years of age and older

SPF-Rx Number of awards: 25 Award amount: Up to $371,616 Length of project period: Up to five years

SPF Rx: Grantees Nooksack Indian Tribe MN WI Little Traverse Bay Band VT ME RI UT NM TX OK IA Cherokee Nation LA OH WV TN MS WY 8 AL0 GA PA NC CT NJ DE MD Southern Plains Tribal Health Board

SPF Rx Cross-Site Evaluation Questions 1. Did SPF Rx implementation improve prescription drug outcomes over time? 2. How was SPF Rx funding leveraged with other funding to address prescription drug misuse and opioid overdose?

SPF Rx Cross-Site Evaluation Questions 3. What factors accounted for variation in performance on grantee- and community-level outcomes across grantees? 4. What are the barriers and facilitators associated with SPF Rx implementation?

CAPT Presentation September 12, 2017 Prevention Planning Using Prescription Drug Monitoring Programs (PDMP) and Other Data Sources: Lessons Learned Sandeep Kasat, Associate Director of Epidemiology, CAPT Core Alyssa O'Hair, Regional Coordinator, CAPT West Resource Team

The Opioid Crisis: Prescription Opioids and Heroin Overdose (OD) Death Trends 18

Why Look at PDMPs? About two-thirds of all opioid overdose deaths are related to prescription opioids PDMPs have been consistently tracking opioid prescriptions for years PDMP data strengths: Available in real time (compared to other health data) Rates by state, county, region/city, and location over time Available by drug type, patient, prescriber, and pharmacy 19

PDMP Data in SAMHSA Initiatives SPF Rx Use PDMP and epidemiological data to identify prevalence; identify and address PDMP data gaps State Targeted Response to the Opioid Crisis Grants (Opioid STR) Use opioid overdose, PDMP, and other epidemiological data to conduct needs assessment; enhance use of PDMPs Grants to Prevent Prescription Drug/Opioid Overdose-Related Deaths (PDO) Needs assessment of prescription drug/opioid overdose issue to identify areas/populations of greatest need 20

Looking at PDMP and Other Data Sources to Understand the Opioid Crisis 21

Prescribing Rates vs. Overdose Deaths in 2015 (PDMP and CDC Wonder) *http://www.pdmpassist.org/content/prescription-behavior-surveillance-system 22

Excessive Dosage and Overdose Deaths by County, California 2013 23

The Opioid Crisis: Overdose Deaths and Misuse Trends Rate per 100K 8 7 6 5 4 3 2 1 Prescription Opioids and Heroin OD Deaths per 100K, CDC Wonder 5.9 5.4 5.4 5.1 5.1 5.1 4.8 4.9 4.6 4 3.7 3.4 3.3 2.9 2.6 2.6 1.9 1.9 1.4 1.6 1.4 0.7 0.7 0.6 0.7 0.7 0.6 0.7 0.7 0.8 1 1.1 1 7 Percent 4 3 2 1 Past Month Non-medical Prescription Painkillers and Heroin Use, NSDUH 1.9 2 1.8 1.9 2.1 2.1 1.9 2.1 2 1.7 1.9 1.7 1.6 0 1999 2003 2007 2011 2015 0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 2002 2005 2008 2011 2014 24

Making Sense of Data Findings Observation Possible Reasons Possible Solutions Opioid prescribing rate age categories do not match with overdose (OD) age categories for older ages Opioid prescribing rate may not be the best indicator for predicting OD deaths Legitimate opioid use more common in older adults Look at doctor shopping/multiple provider episodes Look at additional indicators like patient diagnosis High dosage rate counties do not match with high OD rate counties Age/gender may be playing a confounding role Obtaining prescriptions from a doctor/pharmacy in adjacent county Access to emergency room (ER)/hospital care in a county different than the prescription fill Look at demographic distribution across counties Look at additional indicators (e.g., patient diagnosis, access to care) OD deaths do not match opioid misuse rates Past-month opioid/heroin misuse may not be the best indicator for predicting OD deaths Each data source only gives you one piece of the puzzle. Multiple data sources/indicators can help you see the bigger picture. Look at additional indicators (e.g., high dosage prescriptions, dangerous combinations, ER admissions) 25

Limitations of PDMP Data Access to data is limited by each state s, tribe s, or jurisdiction s legislation Race and ethnicity not recorded on patient s prescription Does not include patient diagnosis (for example, cancer) or physical specialty (for example, pain management clinic) 26

Summary PDMP data is useful, but PDMP data alone may not be helpful in identifying prevention needs. Looking at additional data sources (e.g., overdose, hospitalization, treatment, misuse) can help you identify priorities. PDMP data can be useful in identifying prescribers and pharmacies that should be involved in prevention efforts. 27

Additional Data Sources Center for Disease Control and Prevention Multiple Cause of Death (CDC WONDER)* Agency for Healthcare Research and Quality s (AHRQ) Healthcare Cost and Utilization Project (HCUP)* SAMHSA s Treatment Episode Dataset (TEDS)* Center for Medicare and Medicaid Services Medicare Part D Prescriber Data* SAMHSA s National Survey of Drug Use and Health (NSDUH)* Federal Bureau of Investigation Uniform Crime Reporting (UCR) System American Association of Poison Control Center s National Poison Data System (NPDS) * Available on CAPT s Substance Abuse Prevention Planning and Epidemiology Tool (SAPPET) at www.sappet-epi.com (password: sappet) 28

CAPT Resources on Opioid-related Prevention Planning Data System Substance Abuse Prevention Planning and Epidemiology Tool (SAPPET) Archived Webinars Using Prescription Drug Monitoring Program Data in Prevention Planning Examples of Logic Models for Addressing Opioid-related Overdose Deaths Products Preventing prescription drug misuse: factors and strategies Opioid-related National Data Sources and Indicators Preventing Heroin Use: Facts, Factors, and Strategies 29

Thank you! For more information, please contact: Alyssa O Hair Coordinator, CAPT West Resource Team 775.682.6315 aohair@casat.org Sandeep Kasat CAPT Associate Director of Epidemiology 301.517.4048 SandeepKasat@westat.com 30

Using Prescription Monitoring Program and Other Data for Prescription Drug and Opioid Misuse Prevention in Minnesota Elisabeth Atherly Evaluation Consultant Alcohol and Drug Abuse Division Melissa Adolfson Epidemiologist EpiMachine, LLC 8/28/2017 Minnesota Department of Human Services mn.gov/dhs

Strategic Prevention Framework (SPF) Rx and State Targeted Response (STR) Prevention Partnering with Board of Pharmacy on statewide provider education Funding communities to implement SPF to address Rx drug misuse and illicit opioid use

Prioritization Process Review of potential data sources and indicators: years available, geographic level, strengths, limitations State Epidemiological Outcomes Workgroup vote on final three indicators Rate of opioid prescriptions filled (Prescription Monitoring Program) Rate of opioid overdose deaths (vital statistics) Percent of youth reporting past-year prescription pain reliever misuse (Minnesota Student Survey) 8/28/2017 Minnesota Department of Human Services mn.gov/dhs 33

8/28/2017 Minnesota Department of Human Services mn.gov/dhs 34

Minnesota Prescription Monitoring Program Data Strengths Available at the county level Data exchange with other states Use of PMP by providers and pharmacists is growing Data on 20 types of opioid prescriptions Tracks multiple prescriber and dispenser episodes Limitations County of residence on file with pharmacy not always up to date No data from treatment providers No data from non-indian Health Service tribal providers Limited demographic data Data from 2014 and earlier no longer available 8/28/2017 Minnesota Department of Human Services mn.gov/dhs 35

Other Data Sources Used SOURCE INDICATORS DEMOGRAPHICS GEOGRAPHIC LEVEL Minnesota Student Survey Any Rx misuse Pain reliever misuse Heroin use Rx misuse risk Rx misuse disapproval Grade Sex Race/ethnicity Sexual orientation Gender identity School district Minnesota Survey of Adult Substance Use Pain reliever misuse Heroin use Age Sex Race/ethnicity Sexual orientation Region Vital Statistics/Death Certificate Data Rx opioid overdose deaths Heroin overdose deaths Age Sex Race/ethnicity Zip code 8/28/2017 Minnesota Department of Human Services mn.gov/dhs 36

Other Data Sources Used SOURCE INDICATORS DEMOGRAPHICS GEOGRAPHIC LEVEL Medicaid Claims Data Drug and Alcohol Abuse Normative Evaluation System National Emergency Medical Services Information System* Neonatal abstinence syndrome Maternal opioid use (pain relievers, methadone, buprenorphine) Admissions for heroin as primary-tertiary substance of abuse Admissions for other opioids EMS runs involving overdose EMS runs involving naloxone Age Race/ethnicity Age Sex Race/ethnicity Age Sex Race/ethnicity Zip code County Zip code 8/28/2017 Minnesota Department of Human Services mn.gov/dhs 37

Challenges and Opportunities Enhance collaboration between tribal nations and Board of Pharmacy Collect data on misuse of buprenorphine Evaluate efforts on-reservation, offreservation among tribal youth, and off-reservation among non-tribal youth 8/28/2017 Minnesota Department of Human Services mn.gov/dhs 38

Minnesota Resources Minnesota Prescription Monitoring Program, Reports and Statistics: http://pmp.pharmacy.state.mn.us/reports-andstatistics.html Substance Use in Minnesota: www.sumn.org Minnesota Department of Health, Opioid Dashboard: Coming soon! 8/28/2017 Minnesota Department of Human Services mn.gov/dhs 39

Thank you! Elisabeth Atherly elisabeth.atherly@state.mn.us Melissa Adolfson mboeke@epimachine.com 8/28/2017 Minnesota Department of Human Services mn.gov/dhs 40

NPN Conference Anaheim, CA September 12-13, 2017