Working Group on Blood Pressure and Heart Rate Variability European Society of Hypertension

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Thursday, June 12 Monza (Mi) University of Milano-Bicocca Building U-8 Auditorium Milan (Italy) Working Group on Blood Pressure and Heart Rate Variability European Society of Hypertension Arterial baroreflex sensitivity: methodological aspects and clinical relevance in the new millennium Chairmen: G. Parati (Milan, Italy), M. Di Rienzo (Milan, Italy) Introduction G. Parati (Milan, Italy), M. Di Rienzo (Milan, Italy) Methodological and physiological aspects Chairmen: M. Di Rienzo (Milan, Italy), P.B. Persson (Berlin, Germany) Integrated cardiovascular regulation: neural and non neural mechanisms P.B. Persson (Berlin, Germany) New perspectives from combined computer analysis of BP and HR in assessing cardiovascular regulation M. Di Rienzo (Milan, Italy), G. Parati (Milan, Italy) A new method for assessing spontaneous baroreflex control of the heart K.M. Wessling, B. Westerhof (Amsterdam, The Netherlands) Clinical Aspects I Chairman: G. Parati (Milan, Italy) LECTURE Prognostic value of Autonomic Nervous System Dysfunction S. Julius (Ann Arbor, MI, USA) Coffee Break Clinical Aspects II Chairmen: M. Pagani (Milan, Italy), K. Narkiewicz (Gdansk, Poland) Arterial baroreflex, coronary heart disease and CHF A. Mortara (Monza, Italy) Arterial baroreflex, arterial chemoreflex and CHF L. Bernardi (Pavia, Italy) Arterial baroreflex, SNA and OSAS K. Narkiewicz (Gdansk, Poland) 208 THIRTEENTH EUROPEAN MEETING ON HYPERTENSION

Arterial baroreflex and diabetes mellitus J.L. Elghozi (Paris, France) Arterial baroreflex and neurogenic syncope M.V. Pitzalis (Bari, Italy) Prognostic value of baroreflex sensitivity after acute stroke T.G. Robinson (Leicester, UK) Lunch Autonomic cardiovacular control during space flights: the STS-107 space flight mission on the Columbia Shuttle Chairmen: M. Di Rienzo (Milan,Italy), G. Parati (Milan, Italy) The STS-107 mission. From project details to the tragic end P. Di Palermo (Noordwijk, The Netherlands) Arterial baroreflex and space flights: up-to-date evidence D. Linnarsson (Stockholm, Sweden) The scientific content of the ARMS project in the STS-107 space flight mission J. Karemaker (Amsterdam, The Netherlands) ROUND TABLE DISCUSSION Autonomic cardiovascular regulation during space flights: the italian contribution to the STS-107 mission M. Di Rienzo, F. Iellamo, M. Pagani, G. Parati (Milan and Rome Italy) Conclusions G. Mancia (Milan, Italy) ESH Working Group Business Meeting on Blood Pressure and Heart Rate Variability: Business Meeting This symposium has been accredited by EACCME - UEMS with 6 credits Organizer: Prof. G. Parati Ospedale S. Luca - Istituto Auxologico Italiano Via Spagnoletto 3-20149 Milan - Italy Phone +39 02582161 - Fax +39 0258216712 THIRTEENTH EUROPEAN MEETING ON HYPERTENSION 209

Red Hall 2 Working Group on Blood Pressure Monitoring Blood pressure measurement in hypertension research Welcome E. O Brien (Dublin, Ireland) Blood pressure measurement and outcome Chairman: R. Asmar (Paris, France) 9.05 An international database using ABMP to determine outcome T. Pickering (New York, NY, USA) 9.15 The dabl database : methodology E. Dolan, E. O Brien (Dublin, Ireland) 9.25 Genetic studies are dependent on the blood pressure phenotype J.A. Staessen, V. Tikhonoff (Leuven, Belgium) 9.35 Discussion The role of ABPM in research Chairman: J. Redon (Valencia, Spain) 9.55 Relationship of ABPM to CBPM in patients with isolated systolic hypertension R.H. Fagard (Leuven, Belgium) 10.05 The role of continuous blood pressure in research: the Finapress G.A. van Montfrans (Amsterdam, The Netherlands) 10.15 Assessment of overall BP variability and its different components G. Parati (Milan, Italy) 10.25 Assessment of duration of action of antihypertensive drugs with ABPM M. Myers (Toronto, Canada) 10.35 Discussion 11.00 Coffee Break 210 THIRTEENTH EUROPEAN MEETING ON HYPERTENSION

The role of SBPM in research Chairman: P.L. Padfield (Edinburgh, UK) 11.20 Home BPM versus self- BPM? Which is the correct term? G. Stergiou (Athens, Greece) 11.30 The importance of standardising SBPM: a guideline proposal Y. Imai (Sendai, Japan) 11.40 The role of SBPM in epidemiological studies: the SHEAF study J.M. Mallion (Grenoble, France) 11.50 SBPM versus CBPM and ABPM in pharmacological studies T. Mengden (Bonn, Germany) 12.00 The night/day BP ratio and LV mass in the THOP trial E. den Hond, J.A. Staessen (Leuven, Belgium) 12.10 Discussion 12.30 Closure of the meeting THIRTEENTH EUROPEAN MEETING ON HYPERTENSION 211

Yellow Hall 1 Working Group on Diagnosis and Management of Patients with Multifactorial Cardiovascular Risk An integrative approach to the treatment of the high risk hypertensive patient Chairmen: G. Mancia (Milan, Italy), J.L. Rodicio (Madrid, Spain) 9.00 Introductory remarks G. Mancia (Milan, Italy) 9.05 An integrative view of the mechanisms facilitating CV disease T. Unger (Berlin, Germany) 9.35 Strengths and weaknesses of CV risk assessment B. Williams (Leicester, UK) 10.05 Coffee Break 10.15 The concept of high global CV risk and its relationship to BP (anything beyond 130/80 mmhg is hypertension) B. Waeber (Lausanne, Switzerland) 10.45 LVH and global cardiovascular risk E. Agabiti-Rosei (Brescia, Italy) 11.15 Endothelin damage a common target of CV risk factors S. Taddei (Pisa, Italy) 11.45 Cardiovascular risk in women N.R. Poulter (London, UK) 12.15 Is there any possibility beyond the choice of a diuretic as first step therapy? L.M. Ruilope (Madrid, Spain) 12.45 The concept of the single pill with different components 13.15 Concluding remarks. J.L. Rodicio (Madrid, Spain) 212 THIRTEENTH EUROPEAN MEETING ON HYPERTENSION

Yellow Hall 3 Working Group on Hypertension and Diabetes Chairmen: R. Cifkova (Prague, Czech Republic) P. Nilsson (Malmo, Sweden) 9.00 Welcome P. Nilsson (Malmo, Sweden) 9.05 New epidemiological aspects R. Cifkova (Prague, Czech Republic) 9.30 Nephroprotection in diabetes by antihypertensive treatment M. Ravid (Kfar Sava, Israel) 10.00 Trends in hypertension control in patients with diabetes P. Nilsson (Malmo, Sweden) 10.30 Coffee Break 11.00 Update on meta-analysis of relationship between blood pressure reduction and clinical outcomes in hypertension J. Wang (Bruxelles, Belgium) 11.30 Recent mega-trials in hypertension - Focus on lipids and patients with diabetes S.E. Kjeldsen (Oslo, Norway) 12.00 General Discussion 12.30 Closure of the meeting THIRTEENTH EUROPEAN MEETING ON HYPERTENSION 213

Yellow Hall 2 Working Group on Hypertension and the Kidney Chairman: P.W. de Leeuw (Maastricht, The Netherlands), L.M. Ruilope (Madrid, Spain) 8.55 Opening remarks P.W. De Leeuw (Maastricht, The Netherlands) 9.00-9.30 Determinants of renal aging: focus on hypertension, glucose tolerance and cardiovascular remodeling Ribstein (Montpellier, France) 9.30-10.00 Genetics and renal function in hypertension Spiering (Maastricht, The Netherlands) 10.00-10.30 Endothelial function of the renal vasculature: methodological approach in humans and first results Schneider (Erlangen-Nürnberg, Germany) 10.30-10. 50 Coffee break 10.50-11.20 Estimated GFR as a marker of risk L.M. Ruilope (Madrid, Spain) 11.20-11.50 Kidney protection from antihypertensive agents in renal transplant recipients K. Rahn (Münster, Germany) 11.50-12.20 Vessel wall alterations in patients with chronic renal failure and kidney transplantation Hausberg (Münster, Germany) 12.20 Closing remarks L.M. Ruilope (Madrid, Spain) 214 THIRTEENTH EUROPEAN MEETING ON HYPERTENSION