Maximizing Outcomes in Urologic Oncology

University of California San Francisco The Department of Urology Presents ANNUAL ADVANCED SEMINAR Maximizing Outcomes in Urologic Oncology February 11-12, 2005 Hotel Nikko San Francisco, California COURSE CO-DIRECTORS Peter R. Carroll, MD Professor and Chair of Urology Ken and Donna Derr-ChevronTexaco Distinguished Professor of Prostate Cancer Mack Roach III, MD Professor of Radiation Oncology and Urology Eric J. Small, MD Clinical Professor of Medicine and Urology FEBRUARY 11-12, 2005

DONALD R. SMITH MEMORIAL LECTURER Thomas A. Stamey, MD Professor of Urology, Stanford University Dr. Thomas A. Stamey is a graduate of Johns Hopkins University School of Medicine. He served his internship and urologic residency at the Johns Hopkins Hospital. After two years as a urological consultant to the U.S. Armed Forces in the United Kingdom, he joined the Urology faculty at Johns Hopkins Hospital. In 1961 he accepted the chairmanship of the Stanford University Division of Urology, and he attained full professorship in 1964. Under Dr. Stamey s leadership, the division attained full departmental status in 1990. He served as chairman until 1995. Dr. Stamey has received many honors and awards, including the American Urological Association s Hugh Hampton Young Award and Ramon Guiteras Award. Dr. Stamey was awarded an appointment as Resident Scholar at the Rockefeller Foundation Study and Conference Center in Bellagio, Italy, and membership in Alpha Omega Alpha Honorary Medical Society. He was inducted into the Johns Hopkins Society of Scholars, served as President of the Clinical Society of Genitourinary Surgeons, and was the first urologist elected into the Institute of Medicine of the National Academy of Sciences. He received the Sheen Award of the American College of Surgeons and the Ferdinand Valentine Medal of the New York Academy of Medicine. Dr. Stamey is an Honorary Fellow of the Royal College of Surgeons Edinburgh. As a distinguished scientist-scholar, Dr. Stamey has been or is currently a member of numerous national scientific committees and advisory boards, and an editor or member of the editorial boards of several prestigious journals in medicine. He is a Diplomate of the American Board of Urology and has trained over 70 residents in urology. Dr. Stamey has authored or co-authored over 230 scientific papers, 4 books, 30 textbook chapters, and 7 monographs in his fields of specialization. His research interests have been in renovascular hypertension and physiology; urinary tract infections and incontinence; immunologic characterization of prostatic infections; and cancer of the prostate gland where he has pioneered the use of prostate specific antigen (PSA). Donald R. Smith, MD Professor of Urology, Emeritus, UCSF 1909-1991 Dr. Donald R. Smith received his medical degree from UCSF in 1935, joining the faculty five years later as a Clinical Instructor. In 1951, he succeeded Frank Hinman, Sr., as Chairman of the Division of Urology a position he held for 25 years, training 72 residents. Dr. Smith s major clinical interests were fluid and electrolyte balance, renal physiology, reconstructive surgery (especially hypospadias repair), urinary tract infection, and pediatric urology. In 1957, he conceived and wrote the text, General Urology (now Smith s General Urology). Donald Smith s productive and exemplary career came to an end on August 15, 1991. We remember this great teacher and outstanding clinician with the 2004 memorial lecture.

PRESENTED BY THE UCSF DEPARTMENT OF UROLOGY AND SPONSORED BY THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO SCHOOL OF MEDICINE This course is designed for urologists, medical oncologists, radiation therapists and allied health professionals who evaluate and manage urologic malignancies. Internationally renowned faculty will present the most recent developments and state-of-the-art techniques in this field, with a focus on multidisciplinary care. EDUCATIONAL OBJECTIVES Upon completion of this course, participants should understand and be able to appropriately evaluate: Prostate cancer screening and detection Chemoprevention, nutrition and obesity in prostate cancer Treatment options for localized prostate cancer, including surgery, radiation and minimally invasive techniques Androgen deprivation therapy for advanced prostate cancer: timing, patient selection, and side effects Chemotherapy for prostate, bladder and renal cell cancer Laparoscopy and cytoreductive surgery for renal cell cancer Bladder cancer: BCG failure, chemotherapy/chemoradiation, and bladder replacement surgery COURSE CO-CHAIRS Peter R. Carroll, MD Professor and Chair of Urology Ken and Donna Derr-ChevronTexaco Distinguished Professor of Prostate Cancer Mack Roach III, MD Professor of Radiation Oncology and Urology Eric J. Small, MD Clinical Professor of Medicine and Urology GUEST FACULTY Arie Belldegrun, MD Roy and Carol Doumani Chair in Urologic Oncology Professor of Urology Chief, Division of Urologic Oncology UCLA David Geffen School of Medicine Los Angeles, CA Michael L. Blute, MD Chair, Department of Urology Anson L. Clark Professor of Urology Mayo Clinic Rochester, MN Celestia S. Higano, MD Associate Professor Departments of Medicine and Urology University of Washington Seattle, WA Badrinath R. Konety, MD, MBA Assistant Professor of Urology and Epidemiology Department of Urology University of Iowa Iowa City, IA Alan Pollack, MD, PhD Senior Member and Chairman Department of Radiation Oncology Fox Chase Cancer Center Philadelphia, PA Thomas A. Stamey, MD Professor of Urology Stanford University School of Medicine Stanford, CA UCSF FACULTY June M. Chan, ScD Assistant Professor of Epidemiology and Biostatistics, and Urology Kirsten Greene, MD Senior Research Resident in Urology Christopher J. Kane, MD Associate Professor of Urology Tom F. Lue, MD Professor and Vice Chair of Urology Maxwell Meng, MD Assistant Professor of Urology Brian I. Rini, MD Assistant Clinical Professor of Medicine Jonathan E. Rosenberg, MD Clinical Instructor of Medicine Charles J. Ryan, MD Assistant Clinical Professor of Medicine Katsuto Shinohara, MD Associate Professor of Urology Joycelyn L. Speight, MD, PhD Assistant Clinical Professor of faculty Radiation Oncology

Annual Advanced Seminar: Maximizing Outcomes in Uro 7:00 am Registration and Continental Breakfast PROSTATE CANCER Moderator: Peter Carroll 8:00 Introduction Peter Carroll CANCER SCREENING AND DETECTION 8:05 Chemoprevention: What Did We Learn from the Maxwell Meng Prostate Cancer Prevention Trials? 8:20 Nutrition, Obesity and Prostate Cancer June Chan 8:35 Is More Always Better? The Link Between Volume Badrinath Konety and Outcomes in Urologic Cancer 8:50 PSA Revisited: The Importance of Isoforms and Peter Carroll Velocity 9:10 TRUS-guided Biopsy: Common Errors and Keys Katsuto Shinohara to Success 9:25 Efficient and Reliable Risk Stratification and Staging Kirsten Greene 9:40 Panel Discussion 10:05 Break LOCALIZED DISEASE I Moderator: Katsuto Shinohara 10:20 The Status of Brachytherapy in Contemporary Mack Roach III Treatment of Prostate Cancer 10:40 Minimally Invasive Prostate Surgery: Cryoablation Arie Belldegrun DONALD R. SMITH MEMORIAL LECTURE 10:55 The PSA Era Is Over Thomas Stamey 11:35 Panel Discussion 12:00 Lunch LOCALIZED DISEASE II Moderator: Joycelyn Speight 1:00 The Role of Lymphadenectomy in Improving Badrinath Konety Outcomes from Urologic Cancer Surgery 1:15 Minimally Invasive Prostatectomy: Is It Any Better? Christopher Kane 1:30 Radical Prostatectomy 2005: Improving Cancer Michael Blute Control and Quality of Life 1:50 External Beam Radiation: The Importance of Dose Alan Pollack and Technique and the Role of Prognostic Markers 2:10 Panel Discussion 2:40 Is the Problem Overdetection or Overtreatment? Peter Carroll 2:55 Strategies for Better Recovery of Cavernous Nerve Tom Lue Function after Radical Prostatectomy 3:10 Break FRIDAY, FEBRUARY 11, 2005

logic Oncology The Hotel Nikko San Francisco, California FRIDAY, FEBRUARY 11, 2005 ADVANCED DISEASE Moderator: Charles Ryan 3:25 Brachytherapy Salvage for Rising PSA after Joycelyn Speight External Beam Radiation 3:40 Defining High-risk Biochemical Relapse and the Charles Ryan Timing of Androgen Deprivation 4:00 Monitoring ADT Side Effects Celestia Higano 4:15 Secondary Hormonal Manipulations after the Charles Ryan Failure of ADT 4:30 Monitoring and Treating Bone Loss and Celestia Higano Bone Metastases in Patients with Hormone Refractory Disease 4:45 Chemotherapy: How Effective and for Whom? Charles Ryan 5:05 Panel Discussion 5:30 Adjourn SATURDAY, FEBRUARY 12, 2005 RENAL CELL CANCER Moderator: Christopher Kane 8:00 Is Molecular Profiling Important? Arie Belldegrun 8:15 Improving Techniques in Open Partial Nephrectomy Michael Blute 8:30 Laparoscopy: Impact on Management of Upper Christopher Kane Tract Lesions 8:45 When to Consider Cytoreductive Surgery Arie Belldegrun 9:05 Treating Metastatic Disease: Where Are We? Brian Rini 9:25 Panel Discussion 9:55 Break BLADDER CANCER Moderator: Maxwell Meng 10:10 What Are the Roles of Exfoliated Markers? Badrinath Konety 10:25 Managing the Patient Who Fails BCG Maxwell Meng 10:40 Chemotherapy: Neoadjuvant or Adjuvant? Jonathan Rosenberg 11:00 Chemoradiation: As Effective as Surgery? Alan Pollack 11:20 Bladder Replacement Surgery: Anything New? Michael Blute 11:35 Panel Discussion Noon Adjourn

COURSE REGISTRATION FORM MUR05001 Maximizing Outcomes in Urologic Oncology February 11-12, 2005 Hotel Nikko, San Francisco Dr. Mr. Mrs. Ms. Mail to: UCSF Office of CME Registration Office P.O. Box 45368 San Francisco, CA 94145-0368 Fax: (415) 502-1795 Registration Information: (415) 476-5808 Course Information: (415) 476-4251 Last Name First M.I. Degree Specialty Address City State Zip ( ) ( ) Daytime Phone Fax Email Would you like to be on our priority email list? Yes No Would you like to be on our priority fax list? Yes No Date of birth to be used as OCME registrant number / / X X Month Day Year Please indicate if you have any special needs: Registration Fees: Physicians $395 Allied Health/Resident/Fellow/Nurse $275 Make checks payable to UC Regents Please charge my credit card Visa MasterCard for $ Name on Card (please print) Card # Expiration Date Authorized Signature Refund Policy: Cancellations received in writing on or before February 10, 2005 will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date. www.cme.ucsf.edu

HOTEL RESERVATION FORM MUR05001 Maximizing Outcomes in Urologic Oncology February 11-12, 2005 Hotel Nikko, San Francisco Reservation Deadline: Friday, January 21, 2005** Mail to : Attn: Reservations, Hotel Nikko 222 Mason St. San Francisco, CA 94102 Fax: (415) 394-1106 Reservation Information: (415) 394-1111 Dr. Mr. Mrs. Ms. Last Name First M.I. Address City State Zip ( ) ( ) Daytime Phone Fax Email Arrival Date Departure Date # Persons in Room Special Request: ADA Compliant Other Non-Smoking Accommodation Rates: Single/Double $ 199 Method of Payment: Visa MasterCard Discover Amex Carte Blanche Diner s Club Name on Card (please print) Card # Expiration Date Authorized Signature **Hotel Policies: Reservations must be cancelled at least 72 hours in advance or a onenight s stay (and applicable taxes) will be charged. A credit card number is required to confirm your reservation. Check-in is 3:00 p.m.; check-out is 12:00 noon. Reservation requests made after January 21, 2005 will be honored at the conference roomrates on a space-available basis. Room rates are subject to all state and local taxes (currently 14%, subject to change without notice).

Office of Continuing Medical Education MUR05001 UCSF Box 0742, LH-450 San Francisco, CA 94143-0742 This program is self-supporting and receives no state funding. REGISTER TODAY www.cme.ucsf.edu For more information or to register online visit our website at www.cme.ucsf.edu.you may also reach us by calling the Office of Continuing Medical Education at (415) 476-4251 or email info@ocme.ucsf.edu. NONPROFIT U.S. Postage PAID P I Permit #470 Santa Rosa CA GENERAL INFORMATION Pre-registration is preferred to ensure that registrants receive a syllabus and CME Certificate at the course. HOW TO ENROLL Tuition: $395 Practicing Physicians $275 Allied Health Professionals/ Residents/Fellows Physicians in training must include a letter of verification from training program with registration to qualify for reduced tuition fee. Payment can be made by Visa, MasterCard or check. Register via: Online: www.cme.ucsf.edu Mail: Complete course registration form and send with payment to: UCSF Office of CME P.O. Box 45368 San Francisco, CA 94145-0368 Fax: Fax completed registration form to: (415) 502-1795 (be sure to include your credit card number) To register by phone or to inquire about registration status, please call the UCSF CME Registration Office at (415) 476-5808. REFUNDS Cancellations received in writing on or before February 10, 2005 will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date. ON-SITE REGISTRATION Time: 7:00 am 8:00 am Date: Friday, February 11, 2005 Place: Hotel Nikko 222 Mason Street San Francisco, CA ACCOMMODATIONS A block of guestrooms has been reserved at the Hotel Nikko San Francisco, (415) 394-1111, with a nightly group rate of $199 single/double. Reservations must be received by January 21, 2005, to guarantee availability of the group rate. After this date, rooms will be provided on a space-available basis only. A hotel reservation form is attached for your convenience. If you prefer to phone in your reservation, please identify yourself as a member of this conference to receive the special rate. ACCREDITATION The School of Medicine (UCSF) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. UCSF designates this educational activity for a maximum of 11.75 AMA Physician s Recognition Award category 1 credits. Each physician should claim only those credits that he/she actually spent in the activity. For the purpose of recertification, the American Nurses Credentialing Center accepts AMA PRA category 1 credit issued by organizations accredited by the ACCME.