External respiration Exchange of oxygen and carbon dioxide between the lung and the environment

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Overview of Anatomy and Physiology External respiration Exchange of oxygen and carbon dioxide between the lung and the environment Internal respiration Exchange of oxygen and carbon dioxide at the cellular level Overview of Anatomy and Physiology Upper respiratory tract Nose Pharynx Larynx Trachea Lower respiratory tract Bronchial tree Bronchioles, alveolar ducts, alveoli Overview of Anatomy and Physiology Mechanics of breathing Thoracic cavity Lungs Visceral pleura and parietal pleura Respiratory movements and ranges Rhythmic movements of the chest walls, ribs, and muscles allow air to be inhaled and exhaled Regulation of respiration Nervous control medulla oblongata and pons of the brain; chemoreceptors in the carotid and aorta Assessment of the Respiratory System Subjective data

Shortness of breath, dyspnea, cough Objective data Expression, chest movement, and respirations Respiratory distress, wheezes, or orthopnea Adventitious breath sounds Sibilant wheezes Sonorous wheezes Crackles Pleural friction rubs Laboratory and Diagnostic Examinations Chest roentgenogram Computed tomography (CT) Pulmonary function testing Mediastinoscopy Laryngoscopy Bronchoscopy Sputum specimen Cytological studies Thoracentesis Arterial blood gases Pulse oximetry Figure 49-7 Figure 49-8

Figure 49-9 Disorders of the Upper Airway Epistaxis Bleeding from the nose Congestion of the nasal membranes leading to capillary rupture Primary or secondary Bright red bleeding from one or both nostrils Can lose as much as 1 liter per hour Disorders of the Upper Airway Epistaxis (continued) Sitting position, leaning forward Direct pressure by pinching nose Ice compresses to nose Nasal packing Cautery Balloon tamponade Disorders of the Upper Airway Deviated septum and nasal polyps Congenital abnormality Injury Nasal septum deviates from the midline and can cause a partial obstruction Nasal polyps are tissue growths usually due to prolonged inflammation

Disorders of the Upper Airway Deviated septum and nasal polyps (continued) Stertorous respirations (snoring) Dyspnea Postnasal drip Corticosteroids, antihistamines, antibiotics, analgesics Nasoseptoplasty Nasal polypectomy Disorders of the Upper Airway Allergic rhinitis and allergic conjunctivitis (hay fever) Antigen/antibody reactions in the nasal membranes, nasopharynx, and conjunctiva due to allergens Diagnostic testing Disorders of the Upper Airway Allergic rhinitis and allergic conjunctivitis (continued) Edema Photophobia Excessive tearing Blurring of vision Pruritus Excessive nasal secretions and/or congestion Sneezing

Cough Headache Disorders of the Upper Airway Allergic rhinitis and allergic conjunctivitis (continued) Diagnostic testing Antihistamines Decongestants Corticosteroids Analgesics Avoid allergen Hot packs over facial sinuses Figure 49-3 Disorders of the Upper Airway Obstructive sleep apnea (OSA) Etiology and pathophysiology Characterized by partial or complete upper airway obstruction during sleep Apnea refers to the cessation of spontaneous respirations Hypopnea is the presence of unusually shallow or slow respirations Disorders of the Upper Airway Obstructive sleep apnea (OSA) Clinical manifestations Frequent awakening at night Insomnia Excessive daytime fatigue Witnessed apneic episodes

Loud snoring Hypercapnia Personality changes Irritability Disorders of the Upper Airway Obstructive sleep apnea (continued) Complications Diagnostic tests Avoid sedatives Avoid alcoholic beverages Support groups Oral appliances ncpap Surgery Disorders of the Upper Airway Upper airway obstruction Etiology and pathophysiology Precipitated by a recent respiratory event Common airway obstructions Choking on food Dentures Aspiration of vomitus or secretions The tongue Disorders of the Upper Airway Upper airway obstruction (continued) Stertorous respirations

Altered respiratory rate and character; apneic periods Hypoxia; cyanosis Wheezing; stridor Open the airway Remove obstruction Artificial airway; tracheostomy Disorders of the Upper Airway Cancer of the larynx Squamous cell carcinoma Heavy smoking and alcohol use Chronic laryngitis Vocal abuse Family history Disorders of the Upper Airway Cancer of the larynx (continued) Progressive or persistent hoarseness Pain radiating to the ear Difficulty swallowing Hemoptysis Radiation Surgery Partial or total laryngectomy Radical neck dissection

Respiratory Infections Acute rhinitis (common cold) Inflammation of the mucous membranes of the nose and accessory sinuses Virus(es) Thin, serous nasal exudate Productive cough Sore throat Fever Respiratory Infections Acute rhinitis (common cold) (continued) Analgesic Antipyretic Cough suppressant Expectorant Antibiotic (if infection present) No specific treatment Encourage fluids Respiratory Infections Acute follicular tonsillitis Inflammation of the tonsils Bacterial or viral infection Enlarged, tender, cervical lymph nodes

Sore throat Fever; chills Enlarged, purulent tonsils Elevated WBC Respiratory Infections Acute follicular tonsillitis (continued) Antibiotics; analgesics; antipyretics Warm saline gargles Tonsillectomy and adenoidectomy Postoperative o Assess for excessive bleeding o Ice-cold liquids ice cream o Ice collar o Avoid coughing, sneezing, or vigorous nose blowing Respiratory Infections Laryngitis Inflammation of the larynx due to virus or bacteria May cause severe respiratory distress in children under 5 years old Hoarseness Voice loss Scratchy and irritated throat Persistent cough Respiratory Infections Laryngitis (continued)

Analgesics Antipyretics Antitussives Antibiotics bacterial Viral no specific treatment, supportive care Warm or cool mist vaporizer Limit use of voice Respiratory Infections Pharyngitis Inflammation of the pharynx Chronic or acute Frequently accompanies the common cold Viral, most common Bacterial Respiratory Infections Pharyngitis (continued) Dry cough Tender tonsils Enlarged cervical lymph glands Red, sore throat Fever Antibiotics; analgesics; antipyretics Warm or cool mist vaporizer

Respiratory Infections Sinusitis Inflammation of the sinuses Usually begins with an upper respiratory infection; viral or bacterial Constant, severe headache Pain and tenderness in involved sinus region Purulent exudate Malaise Fever Respiratory Infections Sinusitis (continued) Antibiotics Analgesics Antihistamines Vasoconstrictor nasal spray (Afrin) Warm mist vaporizer Warm, moist packs Nasal windows Acute bronchitis Inflammation of the trachea and bronchial tree Usually secondary to upper respiratory infection

Exposure to inhaled irritants Productive cough; wheezes Dyspnea; chest pain Low-grade fever Malaise; headache Acute bronchitis (continued) Cough suppressants Antitussives Antipyretics Bronchodilators Antibiotics Vaporizer Encourage fluids Legionnaires disease Legionella pneumophila Thrives in water reservoirs Causes life-threatening pneumonia Leads to respiratory failure, renal failure, bacteremic shock, and ultimately death Legionnaires disease (continued)

Elevated temperature Headache Nonproductive cough Difficult and rapid respirations Crackles or wheezes Tachycardia Signs of shock Hematuria Legionnaires disease (continued) Antibiotics Antipyretics Vasopressors Oxygen Mechanical ventilation, if necessary IV therapy Severe Acute Respiratory Syndrome (SARS) Infection caused by coronavirus Spread by close contact between people Airborne May be spread by touching contaminated objects Temperature Headache

Muscle aches Mild respiratory symptoms Dry cough and SOB Adult respiratory distress syndrome (continued) Diagnostic tests Chest radiograph Serum antibody testing Nasopharyngeal and oropharyngeal swabs Antibiotics Antiviral medications Respiratory isolation Oxygen Anthrax Bacillus anthracis Spread by direct contact with bacteria or spores Three types: Cutaneous, GI, inhalational Cold or flu-like symptoms Hemorrhage, tissue necrosis, and lymphedema Medical management Antibiotics

Tuberculosis Inhalation of tubercle bacillus (Mycobacterium tuberculosis) Infection versus active disease Presumptive diagnosis Mantoux tuberculin skin test Chest x-ray film Acid-fast bacilli smear 3 Confirmed diagnosis Sputum culture; positive for TB bacilli Tuberculosis (continued) Fever Weight loss; weakness Productive cough; hemoptysis Chills; night sweats Tuberculosis isolation (acid-fast bacilli [AFB]) Multiple medications to which the organisms are susceptible Pneumonia Inflammatory process of the bronchioles and the alveolar spaces due to infection Bacteria, viruses, mycoplasma, fungi, and parasites Productive cough

Severe chills; elevated temperature Increased heart rate and respiratory rate Dyspnea Pneumonia (continued) Antibiotics Analgesics Expectorants Bronchodilators Oxygen Chest percussion and postural drainage Encourage to cough and deep-breathe Humidifier or nebulizer Pleurisy Inflammation of the visceral and parietal pleura Bacterial or viral Sharp inspiratory pain Dyspnea Cough Elevated temperature Pleural friction rub

Pleurisy (continued) Antibiotics Analgesics Antipyretics Oxygen Anesthetic block for intercostal nerves Pleural effusion/empyema Pleural effusion Accumulation of fluid in the pleural space Empyema infection Dyspnea Air hunger Respiratory distress Fever Pleural effusion/empyema (continued) Thoracentesis Chest tube with closed water-seal drainage system Antibiotics Cough and deep-breathe

Atelectasis Collapse of lung tissue due to occlusion of air to a portion of the lung Dyspnea; tachypnea Pleural friction rub; crackles Restlessness Elevated temperature Decreased breath sounds Atelectasis (continued) Bronchodilators Antibiotics Mucolytic agents Analgesics Cough and deep-breathe Early ambulation Respiratory treatments Incentive spirometry; intermittent positive-pressure breathing (IPPB) Oxygen Chest percussion and postural drainage Chest tube Pneumothorax A collection of air or gas in the pleural space, causing the lung to collapse Decreased breath sounds

Sudden, sharp chest pain with dyspnea Diaphoresis; tachycardia; tachypnea No chest movement on affected side Sucking chest wound Figure 49-13 Pneumothorax (continued) Chest tube to water-seal drainage system Oxygen Analgesics Encourage fluids Lung cancer Primary tumor or metastasis Small-cell, non small-cell, squamous cell, and large-cell carcinoma Hemoptysis Dyspnea; wheezing Fever; chills Pleural effusion Lung cancer (continued) Surgery

Most are not diagnosed early enough for curative surgical intervention Segmental resection Lobectomy Pneumonectomy Radiation Chemotherapy Pulmonary edema Accumulation of serous fluid in interstitial tissue and alveoli Dyspnea; cyanosis Tachypnea; tachycardia Pink or blood-tinged, frothy sputum Restlessness; agitation Wheezing; crackles Decreased urinary output; sudden weight gain Pulmonary edema (continued) Diuretics Narcotic analgesics Nipride Oxygen Mechanical ventilation, if necessary Strict I&O; daily weight Low-sodium diet

Pulmonary embolism Foreign substance in the pulmonary artery Blood clot, fat, air, or amniotic fluid Sudden, unexplained dyspnea, tachypnea Hemoptysis Chest pain Elevated temperature Increased WBCs Pulmonary embolism (continued) Anticoagulants Fibrinolytic agents Oxygen HOB up 30 degrees Acute respiratory distress syndrome (ARDS) Etiology and pathophysiology Results from direct or indirect pulmonary injury Alveolar capillary membranes are altered resulting increased permeability creating pulmonary edema and hypoxia Acute respiratory distress syndrome (continued) Clinical manifestations

Respiratory distress Changes in level of consciousness Tachycardia Hypotension Decreased urinary output Acute respiratory distress syndrome (continued) Corticosteroids Antibiotics Vasodilators Bronchodilators Mucolytics Diuretics Morphine sulfate Neurologic blocking agents Cardiotonic glycosides (digoxin) Acute respiratory distress syndrome (continued) (continued) Oxygen Position changes Close assessment of vital signs Chronic Obstructive Pulmonary Disease (COPD) Emphysema The bronchi, bronchioles, and alveoli become inflamed as a result of chronic irritation

Air becomes trapped in the alveoli during expiration, causing alveolar distention, rupture, and scar tissue Complication Cor pulmonale Right-sided congestive heart failure due to pulmonary hypertension Figure 49-14 Emphysema (continued) Dyspnea on exertion Sputum Barrel chest Chronic weight loss Emaciation Clubbing of fingers Figure 49-16 Emphysema (continued) Bronchodilators; corticosteroids; antibiotics; diuretics Oxygen (low-flow) Chest physiotherapy Humidifier Pursed-lip breathing High-protein, high-calorie diet Chronic bronchitis Hypertrophy of mucous glands causes hypersecretion and alters cilia function Increased airway resistance causes bronchospasm

Productive cough Dyspnea Use of accessory muscles to breathe Wheezing Chronic bronchitis (continued) Bronchodilators Mucolytics Antibiotics Oxygen (low-flow) Pursed-lip breathing Asthma Narrowing of the airways due to various stimuli Extrinsic or intrinsic factors Influenced by secondary factors Antigen-antibody reaction Asthma (continued) Mild asthma Dyspnea on exertion Wheezing Acute asthma attack Tachypnea Expiratory wheezing; productive cough Use of accessory muscles; nasal flaring Cyanosis Asthma (continued)

Maintenance therapy Serevent inhalant, prophylactic Corticosteroid inhalant Avoid allergens Acute or rescue therapy Proventil inhalant; aminophylline IV Corticosteroid and epinephrine oral or subcutaneous Oxygen Bronchiectasis Gradual, irreversible process that involves chronic dilation of bronchi resulting in loss of elasticity Dyspnea; coughing; wheezes and crackles Cyanosis; clubbing of fingers Fatigue; weakness Loss of appetite Bronchiectasis (continued) Mucolytic agents Antibiotics Bronchodilators Oxygen (low-flow) Chest physiotherapy Hydration Cool mist vaporizer Surgery: Lobectomy Nursing Process

Nursing diagnoses Airway clearance, ineffective Breathing pattern, ineffective Gas exchange, impaired Anxiety Activity intolerance Nutrition, imbalanced: less than body requirements