Acronyms and Abbreviations

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Acronyms and Abbreviations 3MS Modified Mini-Mental State Examination AA Arachidonic acid AACD Aging-associated cognitive decline AAMI Age-associated memory impairment ABI Ankle-brachial index ACE Angiotensin 1 converting enzyme ACTIVE Advanced Cognitive Training for Independent and Vital Elderly trial AD Alzheimer s disease ADAPT Alzheimer s Disease Anti-inflammatory Prevention Trial ADAS-Cog Alzheimer Disease Assessment Scale-Cognitive subscale ADEPT Adult Development and Enrichment Project; ADL(s)

Activities of daily living AHRQ Agency for Healthcare Research and Quality amci Amnestic mild cognitive impairment ANS autonomic nervous system ApoE Apolipoprotein E protein APOE Apolipoprotein E gene APOE e4 Epsilon 4 allele of the apolipoprotein E gene APP Amyloid precursor protein ARIC Atherosclerosis Risk in Communities study ASA Acetylsalicylate (aspirin) AVLT Auditory Verbal Learning Test BDI Beck Depression Inventory BMI

Body mass index BNT Boston Naming Test BP Blood pressure BSRT Babcock Story Recall Test BVRT Benton Visual Retention Test CAD Coronary artery disease CASI Cognitive Abilities Screening Instrument CDR Clinical Dementia Rating CDR-SB Clinical Dementia Rating-sum of boxes CEE Conjugated equine estrogen CERAD Consortium to Establish a Registry for Alzheimer s Disease CES-D Center for Epidemiologic Studies Depression scale CHD

Coronary heart disease CHF Congestive heart failure CI Confidence interval CIND Cognitive impairment not demented CNS Central nervous system COPD Chronic obstructive pulmonary disease COWA Controlled Oral Word Association test CRP C-reactive protein CSI-D Community Screening Interview for Dementia CVA Cerebrovascular accident CVD Cardiovascular disease CVLT California Verbal Learning Test DBL

Dementia with Lewy Bodies DBP Diastolic blood pressure DCT Digit Cancellation Test DHA Docosahexaenoic acid DHEA Dehydroepiandosterone DHP-CCB Dihydropyridine-calcium channel blockers; DM Diabetes mellitus DSM Diagnostic and Statistical Manual of Mental Disorders DSST Digit Symbol Substitution Test DWR Delayed word recall EPA Eicosapentaenoic acid EPC Evidence-based Practice Center FTT

Finger Tapping Test GDS Geriatric Depression Scale GEE Generalized estimated equations GRADE Grading of Recommendations Assessment, Development and Evaluation GWAS Genome-wide association studies HDL High density lipoprotein HDL-C High density lipoprotein cholesterol HDRS Hamilton Depression Rating Scale HDDS Hasegawa Dementia Screening Scale HFFQ Harvard Food Frequency Questionnaire HMG-CoA 3-hydroxy-3-methylglutaryl-coenzyme A HMO Health maintenance organization HR

Hazard ratio HRT Hormone replacement therapy HTN IADL IL-1B IL-6 IQ JNC VII LBD LDL MAC MCD MCI Hypertension Instrumental activities of daily living Interleukin-1beta Interleukin-6 Intelligence quotient Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure Lewy Body Dementia Low density lipoprotein Memory assessment clinics Mild cognitive disorder

Mild cognitive impairment MDD Major depressive disorder MeSH Medical Subject Heading MI Myocardial infarction MMSE Mini-Mental State Examination MNC Mild neurocognitive disorder MPA Medroxyprogesterone acetate mtics modified Telephone interview for cognitive status MUFA(s) Monounsaturated fatty acid NCEP-ATPIII National Cholesterol Education Program 3 rd Adult Treatment Panel Guideline NH nursing home NIH National Institutes of Health NIMH

National Institutes of Mental Health NINCDS-ADRDA NS NSAID(s) NYU OMAR OR PDD PMA PUFA(s) PVD RCT RERI National Institute of Neurological and Communicative Diseases and Stroke-Alzheimer s Disease and Related Disorders Association Not statistically significant Non-steroidal anti-inflammatory drug(s) New York University Office of Medical Applications of Research Odds ratio Parkinson's Disease Dementia Primary Mental Abilities Polyunsaturated fatty acid(s) Peripheral vascular disease Randomized controlled trial

Relative excess risk from interaction RR Relative risk RVLT Rey Auditory Verbal Learning Test SBP Systolic blood pressure SCOPE Study on Cognition and Prognosis in the Elderly SD Standard deviation SDMT Symbol Digit Modalities Test SE Standard error SERM Selective estrogen receptor modulator SES Socioeconomic status SF-36 Medical Outcomes Study 36-Item Short Form Health Survey SFA(s) Saturated fatty acid(s) SHEP

Systolic Hypertension in the Elderly Program SNF skilled nursing facility SNP Single-nucleotide polymorphism SPMSQ Short Portable Mental Status Questionnaire STAI State Trait Anxiety Inventory Syst-Eur Systolic Hypertension in Europe trial TBI Traumatic brain injury TEP Technical expert panel TFAM Transcription factor A, mitochondrial TIA Transient ischemic attack TICS Telephone Interview for Cognitive Status TICS-m Telephone Interview for Cognitive Status (modified version) TNK1

Tyrosine kinase, non-receptor 1 Trails A/B Trail Making Test Part A/B Trails B Trail Making Test Part B VA United States Department of Veterans Affairs VAD Vascular Alzheimer s disease VRT Visual Reproduction Test (immediate and delayed recall) from the Wechsler Memory Scale WAIS Wechsler Adult Intelligence Scale WAIS-R Wechsler Adult Intelligence Scale-Revised WF Word Fluency Test WMD Weighted mean difference WMS Wechsler Memory Scale WMS-R Wechsler Memory Scale-Revised