Cours Pasteur. Molecular Cancer Genetics. September 18-29, 2017

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Cours Pasteur Molecular Cancer Genetics September 18-29, 2017 Directors François CLEMENT-BIDARD Co-director, Institut Curie Hospital Jean-Pierre VARTANIAN Co-director, Institut Pasteur PROGRAM 2017-2018

Molecular Cancer Genetics Room 4 & Laboratory ground floor (Building 09, Education center), Institut Pasteur, Paris - Week 1-18 - 22 September 2017 Monday, September 18 9h15-10h00 Course presentation Register office and Education Center presentations 10h30-12h00 Cancer-causing genes: understanding the functions of oncogenes and tumor suppressor genes 14h00-16h00 Molecular cancer: pillars and keystones 16h15-17h00 Practical Work (PW) presentation: Tuesday, September 19 9h00-10h30 Endogenous DNA mutator enzymes 11h00-12h30 Genetic predisposition to cancer 13h30 Wednesday, September 20 9h00-10h30 Regulation of Cell Cycle progression and diseases 11h00-12h30 Oncogenic viruses and the origin of molecular cancer biology Jean-Pierre Vartanian (Institut Pasteur) Chloé Journo (ENS, Lyon) Jean-Christophe Pagès (EFS) Jean-Pierre Vartanian (Institut Pasteur) Pascal Pineau (Institut Pasteur) Group photo Florence Margottin-Goguet (Institut Cochin) Moshe Yaniv (Institut Pasteur)

Thursday, September 21 9h30-12h00 PW: 14h00-17h00 Free Friday, September 22 9h00-10h30 Mechanisms of genome maintenance during antigen receptor diversification 11h00-12h30 Cytokine and Inflammation Analysis of APOBEC3A induced Ludovic Deriano (Institut Pasteur) Jean-Marc Cavaillon (Institut Pasteur)

Molecular Cancer Genetics Institut Curie, Ecole Normale Supérieure (ENS) Paris - Week 2-25 - 29 September 2017 Monday, September 25 (Salle "chez Marie", Institut 9h00-10h30 DNA repair & cancer Marc-Henri Stern (Institut Curie Research, INSERM U830) 10h30-12h00 Genetics & the metastatic process François-Clément Bidard Tuesday, September 26 (Salle "cour anglaise 1&2", level -1, Bâtiment de Biologie du Développement, Institut 9H00-10h30 Genetics & Ethics Guillermo Orsi (Institut Curie Research, CNRS UMR 3664) 10h45-12h15 Genetics of sarcomas Sarah Watson 14h00-15h30 Bioinformatics & interpretation of NGS Nicolas Servant (Institut Curie Research, INSERM U900) 15h30-17h00 Rare allele detection Olivier Lantz (Institut Curie Research, INSERM U932) Wednesday, September 27 (salle "cour anglaise 1&2", level -1, Bâtiment de Biologie du Développement, Institut 9h00-10h30 HPV insertion & cancer Alain Nicolas (Institut Curie Research, CNRS UMR 3244) 10h45-12h15 Cancer immunotherapy Vassili Soumelis (Institut Curie Research, INSERM U932) 14h00-15h30 Epigenetic & cancer Raphael Margueron (Institut Curie Research, CNRS UMR 3215) 15h30-17h00 Genomic instability and telomeres Arturo Londono (Institut Curie Research, CNRS UMR 3244)

Thursday, September 28 (salle "cour anglaise 1&2", level -1, Bâtiment de Biologie du Développement, Institut 9h00-10h30 Molecular genetics of acute leukemia Hugues de Thé (Collège de France / CNRS UMR 7212, INSERM U944) Friday, September 29 (Ecole Normale Supérieure) 9h00-10h00 Steps in biomarker development François-Clément Bidard 10h00-12h00 Journal club François-Clément Bidard 14h00-16h00 Evaluation