Sexually Transmitted Disease (STD) Surveillance Report, 2016

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Sexually Transmitted Disease (STD) Surveillance Report, 2016 Minnesota Department of Health STD Surveillance System STD/HIV/TB Section

Introduction Under Minnesota law, physicians and laboratories must report all laboratory-confirmed cases of chlamydia, gonorrhea, syphilis, and chancroid to the Minnesota Department of Health (MDH) within one working day. MDH does not maintain statistics for other, nonreportable STDs (ex: herpes, HPV/genital warts). This slide set describes trends in reportable STDs in Minnesota by person, place, and time. Analyses exclude cases reported from federal and private prisons.

Introduction STD surveillance is the systematic collection of data from cases for the purpose of monitoring the frequency and distribution of STDs in a given population. STD surveillance data are used to detect problems, prioritize resources, develop and target interventions, and evaluate the effectiveness of interventions.

Interpreting STD Surveillance Data Factors that impact the completeness and accuracy of STD data include: Level of STD screening by healthcare providers Individual test-seeking behavior Sensitivity of diagnostic tests Compliance with case reporting Completeness of case reporting Timeliness of case reporting Increases and decreases in STD rates can be due to actual changes in disease occurrence and/or changes in one or more of the above factors

Interpreting STD Surveillance Data The surveillance system only includes cases with a positive laboratory test. Cases diagnosed solely on symptoms are not counted. Since 2012 we have included cases that had only a lab report and no corresponding case report form. This has increased the number of unknowns in some variables. In 2016, in order to be consistent with CDC, we categorized all White, Hispanic and Black, Hispanic cases as Hispanic. That means the race categories now reflect only White, Non-Hispanic and Black, Non-Hispanic cases Surveillance data represent cases of infection, not individuals. A person with multiple infections in a given year will be counted more than once. Caution is warranted when interpreting changes in STD numbers that can seem disproportionately large when the number of cases is small.

National Context STDs in Minnesota: Annual Review

Chlamydia Rates of Reported Cases by State, United States and Outlying Areas, 2015 NOTE: The total rate of reported cases of chlamydia for the United States and outlying areas (Guam, Puerto Rico, and Virgin Islands) was 475.3 cases per 100,000 population.

Gonorrhea Rates of Reported Cases by State, United States and Outlying Areas, 2015 NOTE: The total rate of reported cases of gonorrhea for the United States and outlying areas (Guam, Puerto Rico, and Virgin Islands) was 122.7 cases per 100,000 population.

Primary and Secondary Syphilis Rates of Reported Cases by State, United States and Outlying Areas, 2015 NOTE: The total rate of primary and secondary syphilis for the United States and outlying areas (Guam, Puerto Rico, and Virgin Islands) was 7.6 cases per 100,000 population.

Overview of STDs in Minnesota STDs in Minnesota: Annual Review

STDs in Minnesota Rate per 100,000 by Year of Diagnosis, 2006-2016 Rate of Chlamydia and Gonorrhea Chlamydia Gonorrhea P&S* Syphilis 450 400 350 300 250 200 150 100 50 0 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year * P&S = Primary and Secondary 10 9 8 7 6 5 4 3 2 1 0 Rate of P&S Syphilis

STDs in Minnesota: Number of Cases Reported in 2016 Total of 28,631 STD cases reported to MDH in 2016: 22,675 Chlamydia cases 5,104 Gonorrhea cases 852 Syphilis cases (all stages) 0 Chancroid cases

CHLAMYDIA

Kittson Roseau Marshall Pennington Red Lake Lake of the Woods Beltrami Koochiching Cook 2016 Minnesota Chlamydia Rates by County Norman Polk Mahnomen Clearwater Itasca St. Louis Lake Hubbard Clay Becker Cass Wadena Wilkin Otter Tail Todd Grant Douglas Morrison Benton Big Stone Stevens Pope Stearns Traverse Swift Kandiyohi Murray Pipestone Cottonwood Blue Earth Watonwan Aitkin Carlton Pine Isanti Chippewa Hennepin Ramsey Lac Qui Parle Yellow Medicine McLeod Renville Carver Scott Dakota Sibley Lincoln Lyon Redwood Goodhue Nicollet Rice Le Sueur Wabasha Brown Crow Wing Mille Lacs Kanabec Sherburne Chisago Anoka Wright Meeker Washington Waseca Steele Dodge Olmsted Winona Rate per 100,000 persons 0-100 101-150 151-300 > 300 City of Minneapolis 1196 City of St. Paul 912 Suburban # 335 Greater Minnesota 298 (890 cases missing residence information) # 7-county metro area, excluding the cities of Minneapolis and St. Paul Rock Nobles Jackson Martin Faribault Freeborn Mower Fillmore Houston

Chlamydia Infections by Residence at Diagnosis Minnesota, 2016 Total Number of Cases = 22,675 Unknown 4% Minneapolis 20% Greater MN 32% St. Paul 12% Suburban 32% Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area.

Chlamydia Rates by Gender Minnesota, 2006-2016 Rate per 100,000 persons 357 371 251 259 144 145 Males Females Overall 470 443 416 390 388 319 340 275 272 292 193 206 158 154 167 484 353 220 504 375 244 528 400 271 560 428 293 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year

Chlamydia Rates by Age Minnesota, 2006-2016 15-19 20-24 25-29 30-39 Rate per 100,000 persons 1363 1423 1162 1018 1059 1539 1507 1220 683 649 669 639 1907 1651 1385 1316 698 719 2015 1458 771 2336 2391 2244 2142 1617 1394 1402 1403 1061 1102 932 843 184 213 217 216 230 242 273 291 348 402 441 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year

Age-Specific Chlamydia Rates by Gender Minnesota, 2016 3500 3325 Males Females Rate per 100,000 persons 3000 2500 2000 1500 1000 500 0 2623 1485 1300 905 659 418 463 88 144 101 92 8 43 24 10 10-14 15-19 20-24 25-29 30-39 40-44 45-49 50+ Age in Years

Chlamydia Rates by Race/Ethnicity Minnesota, 2006-2016 Rate per 100,000 persons White, Non-Hispanic Black, Non-Hispanic American Indian Asian/PI Hispanic* 1825 1727 1631 1661 1611 1619 1587 1519 1527 1524 1517 2016 rates compared with Whites: Black, Non-Hispanic = 9.5x higher American Indian = 5x higher Asian/PI = 2x higher Hispanic* = 3x higher 943 830 730 680 706 744 780 703 653 649 590 480 507 522 424 458 383 405 434 440 376 379 273 265 293 263 284 313 284 289 312 334 342 122 125 130 127 143 162 151 158 178 188 193 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year * Persons of Hispanic ethnicity can be of any race

Chlamydia Rates by Race/Ethnicity Minnesota, 2006-2016 White, Non_Hispanic American Indian Asian/PI Hispanic* 943 Rate per 100,000 persons 730 680 653 649 480 424 458 383 273 265 293 263 122 125 130 127 590 405 284 143 744 706 703 434 376 379 313 284 289 162 151 158 830 780 507 522 440 312 334 342 178 188 193 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year * Persons of Hispanic ethnicity can be of any race

GONORRHEA

Kittson Roseau Marshall Pennington Red Lake Lake of the Woods Beltrami Koochiching Cook 2016 Minnesota Gonorrhea Rates by County Polk Norman Mahnomen Clearwater Hubbard Itasca St. Louis Lake Clay Becker Cass Crow Wing Wadena Aitkin Carlton Wilkin Otter Tail Todd Pine Grant Douglas Morrison Benton Big Stone Stevens Pope Stearns Isanti Chisago Sherburne Traverse Swift Anoka Kandiyohi Wright Meeker Chippewa Ramsey Lac qui Parle Hennepin McLeod Carver Yellow Medicine Renville Scott Dakota Sibley Lincoln Lyon Redwood Goodhue Nicollet Le Sueur Rice Wabasha Brown Murray Cottonwood Blue Earth Steele Dodge Pipestone Olmsted Winona Watonwan Waseca Mille Lacs Kanabec Washington Rate per 100,000 persons 0-10 11-49 50-99 > 100 City of Minneapolis 448 City of St. Paul 271 Suburban # 69 Greater Minnesota 39 (146 cases missing residence information) # 7-county metro area, excluding the cities of Minneapolis and St. Paul Rock Nobles Jackson Martin Faribault Freeborn Mower Fillmore Houston

Gonorrhea Infections in Minnesota by Residence at Diagnosis, 2016 Total Number of Cases= 5,104 Unknown 3% Greater MN 19% Minneapolis 33% Suburban 30% St. Paul 15% Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area.

Gonorrhea Rates by Gender Minnesota, 2006-2016 Males Females Overall 109 Rate per 100,000 persons 74 70 67 64 58 59 63 58 53 48 47 48 44 40 41 43 38 34 63 58 53 76 73 70 92 86 77 77 67 63 96 83 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year

Gonorrhea Rates by Age Minnesota, 2006-2016 15-19 20-24 25-29 30-39 416 360 362 352 Rate per 100,000 persons 285 214 178 75 297 228 186 83 275 214 146 69 216 217 227 165 169 159 117 95 105 50 38 45 290 213 142 65 267 177 86 218 103 238 174 123 302 244 149 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year

Age-Specific Gonorrhea Rates by Gender Minnesota, 2016 Males Females 1 3 17 34 17 22 53 94 90 RATE PER 100,000 PERSONS 144 348 368 235 202 394 436 10-14 15-19 20-24 25-29 30-39 40-44 45-49 50+ AGE IN YEARS

Gonorrhea Rates by Race/Ethnicity Minnesota, 2006-2016 White, Non-Hispanic Black, Non-Hispanic American Indian Asian/PI Hispanic* Rate per 100,000 persons 720 690 591 406 376 410 488 2016 rates compared with Whites: Black, Non-Hispanic = 18x higher American Indian = 9x higher Asian/PI = 2x higher Hispanic* = 3x higher 611 543 518 657 321 217 218 171 132 152 165 102 74 98 70 94 67 24 18 22 47 16 24 19 13 15 13 15 15 16 27 19 32 23 39 31 44 63 34 30 37 35 53 75 81 103 33 37 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year * Persons of Hispanic ethnicity can be of any race

Gonorrhea Rates by Race/Ethnicity Minnesota, 2006-2016 White American Indian Asian/PI Hispanic* 321 Rate per 100,000 persons 171 165 152 132 102 98 94 74 67 70 47 53 34 37 18 24 22 19 24 30 35 27 32 15 15 16 19 23 16 13 13 15 217 218 103 75 81 63 39 44 31 33 37 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 * Persons of Hispanic ethnicity can be of any race. Year

SYPHILIS

Syphilis Rates by Stage of Diagnosis Minnesota, 2006-2016 All Stages P&S* Early Latent 16.1 Rate per 100,000 persons 5 3.6 3.6 4.1 2.2 1.1 0.9 1.1 0.9 1.3 0.9 6.6 6.9 2.8 2.3 2.6 1.4 6.3 2.2 1.8 10.1 3.6 2.6 11.9 12.3 4.8 4.6 3 3.5 5.8 4.7 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 * P&S = Primary and Secondary Year

Kittson Roseau Marshall Pennington Red Lake Polk Norman Mahnomen Clearwater Lake of the Woods Beltrami Koochiching Itasca St. Louis Lake Cook 2016 Minnesota Primary & Secondary Syphilis Rates by County Hubbard Clay Becker Cass Wilkin Traverse Big Stone Rock Grant Stevens Lac qui Parle Otter Tail Lyon Nobles Swift Yellow Medicine Lincoln Pipestone Murray Douglas Pope Chippewa Redwood Jackson Wadena Todd Kandiyohi Renville Cottonwood Stearns Brown Meeker Martin Morrison McLeod Sibley Nicollet Crow Wing Benton Wright Faribault Carver Mille Lacs Sherburne Le Sueur Aitkin Scott Isanti Anoka Hennepin Rice Freeborn Kanabec Dakota Steele Watonwan Blue Earth Waseca Chisago Carlton Washington Pine Goodhue Dodge Olmsted Mower Wabasha Fillmore Winona Houston Rate per 100,000 persons 0 0.8 3.0 3.1 9.2 > 9.2 Ramsey City of Minneapolis 33.7 (129 cases) City of St. Paul 8.1 (23 cases) Suburban # 3.1 (68 cases) Greater Minnesota 1.1 (26 cases) # 7-county metro area, excluding the cities of Minneapolis and St. Paul

Primary & Secondary Syphilis Infections in Minnesota by Residence at Diagnosis, 2016 Total Number of Cases = 306 Greater MN 18% Unknown 0% Minneapolis 42% Suburban 31% St. Paul 9% Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area.

Primary & Secondary Syphilis Rates by Gender Minnesota, 2006-2016 12 Females Overall Males 10.1 10 Rate per 100,000 persons 8.9 7.9 6.8 5.8 5.4 5.1 4.8 4.6 4.3 4.2 3.6 2.7 2.8 2.6 2.2 2.2 2.2 1.7 1.5 1.4 0.9 1.1 1.3 0.8 0.2 0 0.2 0.3 0 0.2 0.3 0.4 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year 8 6 4 2 0

Primary & Secondary Syphilis Rates by Age Minnesota, 2006-2016 Rate per 100,000 persons 3.3 2.9 2.4 2.5 2 1.4 1.4 0.5 0.5 6.7 4.9 4.1 0.8 15-19 20-24 25-29 30-39 40-49 11.3 9.6 9.3 7.3 7.5 7 6.4 5.5 4.8 5.1 4.9 4.5 4 4.2 3.8 3.4 3 2.3 1.6 0.5 0.8 1.1 0.5 14.9 14.6 13.4 13.4 13.8 13.1 9.4 9.5 7 7 5.4 5.9 3.8 2.7 2.7 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year D

Age-Specific Primary & Secondary Syphilis Rates by Gender, Minnesota, 2016 Rate per 100,000 persons 30 25 20 15 10 5 0 Males Females 15-19 20-24 25-29 30-39 40-44 45-49 50+ Age in Years

Primary & Secondary Syphilis Cases by Race Minnesota, 2016 Total Number of Cases = 306 Asian/PI 6% Unknown 3% Hispanic 9% American Indian 6% White, Non- Hispanic 53% Black, Non- Hispanic 23% *Includes persons reported with more than one race

Rate per 100,000 persons 30 25 20 15 10 5 Primary & Secondary Syphilis Rates by Race/Ethnicity Minnesota, 2006-2016 White, Non-Hispanic American Indian Hispanic Black, Non-Hispanic Asian/PI 0 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 * Persons of Hispanic ethnicity can be of any race. Year

CHLAMYDIA AND GONORRHEA AMONG ADOLESCENTS & YOUNG ADULTS Minnesota Department of Health STD Surveillance System STD/HIV/TB Section

Chlamydia Disproportionately Impacts Youth 25-34 yrs 13% MN Population in 2010 (n = 5,303,925) 35+ yrs 53% Chlamydia Cases in 2016 (n = 22,675) 25-29 yrs 18% 30-44 yrs 15% 15-24 yrs 14% <15 yrs 20% 15-24 yrs 64% <15 yrs 1% 45+ yrs 2%

Gonorrhea Disproportionately Impacts Youth 25-34 yrs 13% MN Population in 2010 (n = 5,303,925) 35+ yrs 53% Gonorrhea Cases in 2016 25-29 yrs 22% (n = 5,104) 30-44 yrs 24% 45+ yrs 7% 15-24 yrs 14% <15 yrs 20% 15-24 yrs 46% <15 yrs 1%

Characteristics of Adolescents & Young Adults Diagnosed With Chlamydia or Gonorrhea in 2016 Cases % of Total Male 4,984 29% Female 11,832 71% Transgender 12 White, Non-Hispanic 6,072 36% Black, Non-Hispanic 4,555 27% Am Indian 466 3% Asian/PI 481 3% Hispanic Other/Unknown 946 4,309 6% 26% TOTAL 16,829 Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Characteristics of Adolescents & Young Adults Diagnosed With Chlamydia or Gonorrhea in 2016 Cases % of Total Minneapolis 3,261 19% St. Paul 2,060 12% Suburban MN 5,312 32% Greater MN 5,519 33% Unknown 687 4% TOTAL 16,829 Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Chlamydia Rates Among Adolescents & Young Adults by Gender in Minnesota, 2006-2016 Rate per 100,000 persons 1871 1955 531 544 Males Females 2646 2690 2745 2780 2506 2334 2103 2124 812 845 871 924 980 620 629 661 2970 1063 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Chlamydia Cases Among Adolescents and Young Adults by Gender and Race, Minnesota, 2016 Males (n = 3,925) Females (n = 10,519) White 34% Black 30% White 40% Black 22% Amer Indian 2% Unknown 26% Hispanic 5% Amer Indian 2% Asian/PI 3% Unknown 27% Hispanic 6% Asian / PI 3% Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Chlamydia Rate Among Adolescents and Young Adults by Race, Minnesota, 2016 Males Females 450 1475 1446 478 1563 893 RATE PER 100,000 PERSONS 4608 9592 5117 3035 WHITE, NON- HISPANIC BLACK, NON- HISPANIC AMERICAN INDIAN ASIAN/PI HISPANIC Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Gonorrhea Rates Among Adolescents & Young Adults by Gender in Minnesota, 2006-2016 Males Females 401 337 355 320 337 329 371 Rate per 100,000 persons 165 172 171 249 134 263 258 125 129 167 228 250 283 240 287 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Gonorrhea Cases Among Adolescents and Young Adults by Gender and Race, 2016 Males (n = 1059) Females (n = 1313) White, Non- Hispanic 25% Black, Non- Hispanic 45% Black, Non- Hispanic 45% Amer Indian 5% Unknown 16% Hispanic 6% Other 1% Amer Indian 4% Asian/PI 3% White, Non- Hispanic 17% Unknown 27% Hispanic 3% Asian / PI 2% Other 1% Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Gonorrhea Rate Among Adolescents and Young Adults by Race, Minnesota, 2016 Males Females 90 96 148 145 288 263 811 RATE PER 100,000 PERSONS 1860 2199 987 WHITE, NON- HISPANIC BLACK, NON- HISPANIC AMERICAN INDIAN ASIAN/PI HISPANIC Rate=Cases per 100,000 persons based on 2010 U.S. Census counts. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Summary of Chlamydia and Gonorrhea Among Adolescents and Young Adults, Minnesota, 2016 Adolescents and young adults accounted for 64% of chlamydia and 46% of gonorrhea cases diagnosed in Minnesota. 70% of chlamydia or gonorrhea cases diagnosed among adolescents and young adults were females. 25% of chlamydia and gonorrhea cases diagnosed among adolescents and young adults are missing race/ethnicity 31% of gonorrhea or chlamydia cases were in the Cities of Minneapolis and Saint Paul. Adolescents defined as 15-19 year-olds; Young Adults defined as 20-24 year-olds.

Topic of Interest: Early Syphilis Among Men Who Have Sex With Men in Minnesota Minnesota Department of Health STD Surveillance System STD/HIV/TB Section

Number of Early Syphilis Cases by Gender Minnesota, 2006-2016 All Male MSM Women 468 Number of Cases 374 359 341 298 283 261 247 209 218 222 185 196 158 158 138 111 103 106 91 96 82 88 87 30 41 14 2 5 9 15 13 18 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year MSM=Men who have sex with men. Figure does not include cases diagnosed in transgender persons (1 each in 2005, 2007, 2009, 4 in 2013, 1 in 2014, 2 in 2015). Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Early Syphilis Cases by Stage at Diagnosis Minnesota, 2006-2016 557 Number of Cases 332 416 431 163 105 114 117 58 71 55 45 27 38 47 46 41 20 21 30 259 221 214 120 98 88 96 72 66 51 51 52 139 117 76 159 156 101 251 185 164 132 142 114 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Year Primary Secondary Early Latent Total Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Early Syphilis by Gender and Sexual Behavior Minnesota, 2006-2016 Year Early Syphilis Cases Male Cases (%) MSM Cases (% of males) 2006 104 90 (88) 80 (89) 2007 114 111 (97) 103 (93) 2008 163 158 (97) 140 (89) 2009 117 106 (91) 96 (91) 2010 221 207 (94) 185 (89) 2011 260 246 (95) 218 (89) 2012 214 196 (92) 158 (81) 2013 332 298 (90) 261 (88) 2014 416 374 (90) 283 (76) 2015 431 341 (79) 222 (65) 2016 557 468 (84) 359 (77) MSM=Men who have sex with men Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Early Syphilis Cases Among MSM by Age Minnesota, 2016 (n=359) Mean Age = 36 years Range: 16 to 72 years NUMBER OF CASES 55 66 57 49 38 37 28 21 8 15-19 20-24 25-29 30-34 35-39 40-44 45-49 50-54 55+ AGE IN YEARS MSM=Men who have sex with men Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Early Syphilis (ES) Cases Co-infected with HIV, 2006-2016 All ES Cases Percent HIV Positive 59% 57% 57% 56% 54% 48% 50% 49% 49% 47% 46% 45% 45% 46% 44% 41% 40% 38% 38% 37% 32% 30% 2006 2007 2008 2009 2010 2011 Year 2012 2013 2014 2015 2016 MSM=Men who have sex with men Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Characteristics of Early Syphilis Cases Among MSM, Minnesota, 2016 Gay and bisexual men account for 77% of cases among men. 62% of cases among MSM are White, but a disproportionate number of cases (17%) are African American. 44% of cases are also infected with HIV. MSM=Men who have sex with men Early Syphilis includes primary, secondary, and early latent stages of syphilis.

Topic of Interest: Syphilis Among Females and Congenital Syphilis in Minnesota Minnesota Department of Health STD Surveillance System STD/HIV/TB Section

Female Early Syphilis cases 109 83 88 87 Number of Cases 74 52 41 30 22 17 7 10 13 22 12 9 6 8 14 2 5 9 14 13 18 Year

Early Syphilis Infections in Women in Minnesota by Residence at Diagnosis, 2016 Total Number of Cases = 87 Greater MN 18% Unknown 0% Minneapolis 38% Suburban 25% St. Paul 19% Suburban = Seven-county metro area including Anoka, Carver, Dakota, Hennepin (excluding Minneapolis), Ramsey (excluding St. Paul), Scott, and Washington counties. Greater MN = All other Minnesota counties outside the seven-county metro area.

Early Syphilis Cases in Females by Race Minnesota, 2016 Total Number of Cases = 87 Asian/PI 4% Hispanic 7% Unknown 2% White, Non- Hispanic 33% American Indian 15% *Includes persons reported with more than one race Black, Non- Hispanic 39%

What s Being Done in Minnesota? The MDH Partner Services Program continues to follow up on early syphilis cases and their sex partners and all pregnant syphilis cases. All HIV/Syphilis co-infected cases are assigned to Partner Services for follow-up. Physicians are encouraged to screen men who have sex with men at least annually and to ask about sex partners. All pregnant females should be screened for syphilis at first prenatal visit, 28 weeks gestation (at minimum 28-36 weeks), and at delivery.

STD Surveillance Summary Minnesota Department of Health STD Surveillance System STD/HIV/TB Section

Summary of STD Trends in Minnesota From 2006-2016, the chlamydia rate increased by 71%. The rate of gonorrhea increased by 25%. Rates of reported syphilis increased in 2016 compared to 2015 by 30%. Minnesota has seen a resurgence of syphilis over the past decade, with men who have sex with men and those co-infected with HIV being especially impacted. However, the number of females is near the record high for the last decade. Persons of color continue to be disproportionately affected by STDs. STD rates are highest in the cities of Minneapolis and Saint Paul. However, chlamydia and gonorrhea cases in the Twin Cities suburbs and Greater Minnesota account for 61% of the reported cases in 2016. Between 2015 and 2016, early syphilis cases increased by 29%. Men who have sex with men comprised 77% of all male cases in 2016; cases among women are continuing to remain high.

Future Updates to STD Reporting and Current Follow-Up New case report form to accommodate changes in treatment guidelines, requesting HIV testing status, and PreP usage. Case report form is be able to be filled out on a computer and printed to be mailed or faxed in All cases co-infected with HIV (diagnosed in the last year)/gonorrhea, HIV/Syphilis, and Early Syphilis will be continue to be assigned to MDH Partner Services for followup All Gonorrhea cases continue to have the potential for being contacted by MDH for additional follow-up