MILAN CARDIOLOGY. Milan (Italy), February, 13 th - 15 th, 2014 PROGRAM. Menarini Foundation Symposia: 243. Organized by.

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02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 1 Menarini Foundation Symposia: 243 MILAN CARDIOLOGY, February, 13 th - 15 th, 2014 Organized by Promoted by PROGRAM San Raffaele Congress Centre (Via Olgettina, 58)

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 3 MILAN CARDIOLOGY, February, 13 th - 15 th, 2014 Organized by Promoted by PROGRAM San Raffaele Congress Centre (Via Olgettina, 58)

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 2 Under the Auspices of Associazione Nazionale Brigham and Women s Hospital Società Italiana di Cardiologia Medici Cardiologi Ospedalieri Sistema Sanitario Regione Lombardia OMCeO Milano Dear Colleagues, it is a great pleasure to invite you to the International Congress Milan Cardiology, to be held on February 13 th - 15 th, 2014 at the Ospedale San Raffaele in Milan. This second meeting will provide an in depth update on some of the hottest topics in Cardiology. Each session will cover new epidemiological and pathophysiological issues together with invasive and non invasive diagnostics and treatment for each condition. All this will be only possible through an outstanding international Faculty that will see together some of the world s experts in the field. I hope that the Milan Cardiology 2014 will be an extremely productive meeting, able to provide you with a valid opportunity to improve your understanding of this complex and rapidly evolving area of medicine. I look forward to welcoming you in Milan next February. Paolo G. Camici Chairman Chairman Paolo G. Camici Full Professor of Cardiology, (Milan, Italy) Head of Myocardial Diseases Center, (Milan, Italy) Scientific Committee Ottavio Alfieri, Robert Bonow, Domenico Cianflone, Antonio Colombo, Paolo Della Bella, Peter Libby, Aldo Pietro Maggioni, Alberto Margonato, Marc Pfeffer, Paul Ridker, Ornella E. Rimoldi Organising Secretariat San Raffaele Congress Centre Via Olgettina, 58 I-20132 Phone +39 02 2643 6227 Fax +39 02 2643 3754 E-mail: info@milancardiology2014.com Http://www.milancardiolology2014.com Promoted by Fondazione Internazionale Menarini Via W. Tobagi, 8 I-20068 Peschiera Borromeo (Milan, Italy) Phone: +39 02 55308110 Fax: +39 02 55305739 E-mail: milan@fondazione-menarini.it Http://www.fondazione-menarini.it 2 CME Provider - MZ Congressi - PROVIDER ID: 966 3

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 4 Thursday, February 13 th, 2014 - Morning Thursday, February 13 th, 2014 - Morning 8.00-8.30 Introduction to the Meeting by Local Authorities Session II Arterial Hypertension (HT) and End Organ Damage Session I Chair: Atherosclerosis, Inflammation and Plaque Vulnerability P. Libby (Boston, USA) C. Borghi (Bologna, I) Chair: M. Volpe (Rome, I) G. Grassi (Milan, I) 10.45-11.05 S. Laurent (Paris, F) Vascular Stiffness in HT 8.30-8.50 R. Virmani (Washington, USA) Anatomy and Pathology of the ATS Plaque 8.50-9.10 F. Crea (Rome, I) Evidence Linking Plaque Vulnerability and Inflammation 9.10-9.30 J. Lima (Baltimore, USA) The MESA Study 9.30-9.50 A. Hamsten (Stockholm, S) Functional Genomics 9.50-10.10 P.M. Ridker (Boston, USA) Inhibition of Inflammation and Vascular Events: The CANTOS and CIRT Trials 11.05-11.25 B. Trimarco (Naples, I) Diastolic Dysfunction in HT 11.25-11.45 G. Grassi (Milan, I) Metabolic Profile in HT 11.45-12.05 C. Borghi (Bologna, I) Pregnancy-Induced HT and Heart Disease 12.05-12.25 M. Volpe (Rome, I) Hypertension and Stroke 12:25-12:40 Discussion 12.40-13.10 Lectio Magistralis 10.10-10.25 Discussion 10.25-10.45 Coffee break Chair: P.M. Ridker (Boston, USA) P.G. Camici (Milan, I) P. Libby (Boston, USA) Inflammation and Atherothrombosis: an Update 13.10-14.00 Lunch 4 5

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 6 Thursday, February 13 th, 2014 - Afternoon Thursday, February 13 th, 2014 - Afternoon Session III Coronary Microvascular Dysfunction (CMD) Session IV Cardiac Imaging for Risk Stratification Chair: F. Crea (Rome, I) D. Cianflone (Milan, I) Chair: M.F. Di Carli (Boston, USA) O.E. Rimoldi (Milan, I) 14.00-14.20 G. d Amati (Rome, I) Coronary Microvascular Remodelling 14.20-14.40 P.G. Camici (Milan, I) CMD in Primary and Secondary LVH 14.40-15.00 J. Knuuti (Turku, FI) Reversibility of CMD in Patients with Risk Factors 15.00-15.20 M.F. Di Carli (Boston, USA) Prognostic Impact of CMD in Patients with CAD 15.20-15.40 M. Marzilli (Pisa, I) Implications of MVO in Patients with STEMI 15.40-15.50 L. Monti (Milan, I) A novel truncated form of enos and vascular function 15.50-16.00 Discussion 16.00-16.15 Coffee Break 16.15-16.35 D. Andreini (Milan, I) The CONFIRM Trial and Beyond 16.35-16.55 F. De Cobelli (Milan, I) No Reflow in STEMI: CMR vs TIMI, a Change of Paradigm 16.55-17.15 S.K. Prasad (London, UK) CMR Late Enhancement 17.15-17.35 D. Neglia (Pisa, I) The EVINCI Trial 17.35-17.55 M. Pepi (Milan, I) Which Technique and When 17.55-18.10 Discussion Debate - Quantification of Myocardial Perfusion and Risk Stratification Chair: J. Knuuti (Turku, FI) A. Roghi (Milan, I) 18.10-18.30 P.G. Camici (Milan, I) PET Has Shown the Way 18.30-18.50 S. Plein (Leeds, UK) CMR Should Become the Clinical Tool 6 7

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 8 Friday, February 14 th, 2014 - Morning Friday, February 14 th, 2014 - Morning Session V Ischemic Heart Disease Session VI Ischemic Heart Disease Chair H. Shimokawa (Tohoku, J) B. De Bruyne (Aalst, B) 8.30-8,50 M. Simoons (Rotterdam, NL) The Changing Picture of ACS 8.50-9.10 F. Crea (Rome, I) Pathogenetic Classification of ACS 9.10-9.30 M. Marzilli (Pisa, I) Did the Outcome of Patients with ACS Change over the Past 10 Years? 9.30-9.50 S. De Servi (Legnano, MI - I) New Anti-Platelets Drugs in Acute Coronary Syndromes 9.50-10.10 R. De Caterina (Chieti, I) New Anti-Coagulant Drugs for Long Term Treatment 10.10-10.25 Discussion 10.25-10.45 Coffee Break Chair: R. De Caterina (Chieti, I) A. Margonato (Milan, I) 10.45-11.05 H. Shimokawa (Tohoku, J) Vasospastic Angina: the Japanese Registry 11.05-11.25 S.H. Baek (Seoul, ROK) Class Differences in Calcium-Channel Blockers in Vasospastic Angina 11.25-11.45 B. De Bruyne (Aalst, B) FFR Guided Revascularization: the FAME Studies 11.45-12.05 A. Bartorelli (Milan, I) Bio-Absorbable Stents 12.05-12.25 G. Ambrosio (Perugia, I) New Anti-Ischemic/Anginal Drugs 12.25-12.40 Discussion 12.40-13.10 Lectio Magistralis Chair P.G. Camici (Milan, I) T.F. Lüscher (Zurich, CH) D.A. Wood (London, UK) The Challenge of Cardiovascular Prevention 13.10-14.00 Lunch 8 9

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 10 Friday, February 14 th, 2014 - Afternoon Friday, February 14 th, 2014 - Afternoon Session VII Heart Failure Multiple Interfaces Under the Auspice of Chair: M. Pfeffer (Boston, USA) A.P. Maggioni (Florence, I) 14.00-14.20 A.P. Maggioni (Florence, I) The Updated Clinical Epidemiology of HF Session VIII Heart Failure Chair S.D. Anker (Berlin, D) J. Holzmeister (Zurich, CH) 16.15-16.35 M. Pfeffer (Boston, USA) HF with Preserved EF: the TOPCAT Trial Under the Auspice of 14.20-14.40 S.D Anker (Berlin, D) Management of Co-Morbidities in HF - Anemia, Iron Deficiency, Cardio Renal Syndrome 14.40-15.00 M.R. Cowie (London, UK) New Therapeutic Approaches for Acute and Chronic HF 15.00-15.20 R. Cappato (Milan, I) AF: is Ablation the Best Option? 15.20-15.40 O. Alfieri (Milan, I) Percutaneous Mitral Valve Repair in Functional Mitral Insufficiency 15.40-15.55 Discussion 15.55-16.15 Coffee break 16.35-16.55 M.R. Cowie (London, UK) Strategies for Prevention of LV Remodelling 16.55-17.15 A. Rinaldi (London, UK) Cardiac Resynchronization Therapy 17.15-17.35 O.E. Rimoldi (Milan, I) Imaging Cardiac Sympathetic Innervation as a Guidance for Treatment 17.35-17.55 M. Frigerio (Milan, I) Heart Transplantation: 25 Years Single-Centre Experience 17.55-18.15 T.F. Lüscher (Zurich, CH) Cell, Tissue Engineering and Gene-Based Therapies 18.15-18.30 Discussion Debate - Level of Adherence to the HF Guidelines and Implications on Outcome Chair M.R. Cowie (London, UK) M. Frigerio (Milan, I) 18.30-18.50 M. Pfeffer (Boston, USA) The US Experience 18.50-19.10 A.P. Maggioni (Florence, I) The EU Experience 10 11

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 12 Saturday, February 15 th, 2014 - Morning Saturday, February 15 th, 2014 - Morning Session IX Diseases of the Myocardium Session X Valve Disease Chair G. Thiene (Padua, I) P.M. Elliott (London, UK) Chair R.O. Bonow (Chicago, USA) O. Alfieri (Milan, I) 8.30-8.50 P.M. Elliott (London, UK) Update on Classification of Cardiomyopathies 8.50-9.10 I. Olivotto (Florence, I) Genotype-Phenotype Interactions in HCM 9.10-9.30 H.P. Schultheiss (Berlin, D) Pathophysiology, Clinical Course and Management of DCM 9.30-9.50 C. Basso (Padua, I) Pathophysiology, Diagnosis and Management of Arrhythmogenic Right Ventricular CMP 9.50-10.10 P. Della Bella (Milan, I) Epicardial Management of CMP-Related Ventricular Tachycardia 10.10-10.25 Discussion 10.25-10.55 Lectio Magistralis 11.15-11.35 R.O. Bonow (Chicago, USA) Aging and the New Burden of Valve Disease 11.35-11.55 G. La Canna (Milan, I) Imaging-Guided Treatment Strategies 11.55-12.15 N. Moat (London, UK) TAVI Twelve Years After 12.15-12.35 O. Alfieri (Milan, I) The Evolution from Surgery to Percutaneous Mitral Valve Interventions 12.35-12.55 A. Vahanian (Paris, F) Management after Valve Replacement 12.55-13.10 Discussion Meeting ends Chair P.G. Camici (Milan, I) R. Chiesa (Milan, I) 10.55-11.15 Coffee break G. Thiene (Padua, I) The Concept of Non-Ischemic Disease of the Myocardium: a Historical Survey 12 13

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 14 GENERAL INFORMATION Meeting venue The venue of the Meeting will be the San Raffaele Congress Centre (Via Olgettina, 58 - Milan, Italy). Phone +39 02 2643 6227 - Fax +39 02 2643 3754. Secretariat during the Meeting The Secretariat will be opened at the following times: Thursday, February 13 th, from 07.30 a.m. to 06.30 p.m. Friday, February 14 th, from 08.00 a.m. to 07.00 p.m. Saturday, February 15 th, from 08.00 a.m. to 01.30 p.m. Official Language The official language of the Congress is English. Simultaneous translation Italian/English/Italian will be provided. Registration The Meeting is free to attend. Please return the Registration form to: San Raffaele Congress Centre - Via Olgettina 58 20132 - E-mail: info@milancardiology2014.com - Fax: +39 02 2643 3754 or visit the official website www.milancardiology2014.com for the online registration. EBAC The Congress will be included in the Educational Program of the European Board for Accreditation in Cardiology. CME Credits The Congress will be included in the C.M.E. Program of the Italian Ministry fo Health. Technical facilities Facilities will be available for computer presentations and overhead projections. A slide center with PC (Powerpoint for Windows) will be available for check and preview of presentations. It is essential that speakers take their presentation to the slide center at least one hour before the session starts. It will be opened at the following times: Thursday, February 13 th, from 07.30 a.m. to 06.30 p.m. Friday, February 14 th, from 08.00 a.m. to 07.00 p.m. Saturday, February 15 th, from 08.00 a.m. to 01.30 p.m. Lunches and coffee breaks Lunches and coffee breaks will be served in the Meeting area. Certificate of attendance The certificate of attendance will be available on request at the end of the Meeting at the Secretariat. 14 LIST OF CHAIRMAN, SCIENTIFIC COMMITTEE AND INVITED FACULTY CHAIRMAN Paolo G. Camici SCIENTIFIC COMMITTEE Ottavio Alfieri Cardiac Surgery Division Robert O. Bonow Centre of Cardiovascular Innovation Northwestern University Feinberg School of Medicine Chicago (IL, USA) Domenico Cianflone Cardiovascular Rehabilitation Unit Antonio Colombo Interventional Cardiology and Hemodynamics Division Paolo Della Bella Arrhythmology and Cardiac Electrophysiology Division Peter Libby Service of Cardiovascular Medicine Brigham and Women s Hospital Boston (MA, USA) 15

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 16 Aldo Pietro Maggioni Centro Studi A.N.M.C.O. Florence (Italy) Alberto Margonato Clinical Cardiology and CCU Division Marc Pfeffer Brigham and Women s Hospital Boston (MA, USA) Paul M. Ridker Center of Cardiovascular Disease Prevention Brigham and Women s Hospital Boston (MA, USA) Ornella Rimoldi IBFM-CNR INVITED FACULTY Ottavio Alfieri Giuseppe Ambrosio Università degli Studi di Perugia Ospedale Santa Maria della Misericordia Perugia (Italy) Daniele Andreini Centro Cardiologico Monzino Stefan D. Anker Medizinische Klinik m. S. Kardiologie Berlin (Germany) Sang Hong Baek The Catholic University of Korea School of Medicine Seoul (South Korea) Antonio Bartorelli Centro Cardiologico Monzino Cristina Basso Università degli Studi di Padova Padua (Italy) Robert O. Bonow Northwestern University Feinberg School of Medicine Chicago (IL, USA) Claudio Borghi Università degli Studi di Bologna Bologna (Italy) Riccardo Cappato IRCCS Policlinico San Donato San Donato M.se (Milan, Italy) Roberto Chiesa Domenico Cianflone Martin R. Cowie Imperial College London London (United Kingdom) Filippo Crea Università Cattolica del Sacro Cuore Policlinico Universitario Agostino Gemelli Rome (Italy) 16 17

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 18 Giulia d Amati Sapienza - Università di Roma Rome (Italy) Bernard De Bruyne O.L.V. Ziekenhuis Aalst (Belgium) Raffaele De Caterina Università degli Studi G. D Annunzio Chieti, Italy Francesco De Cobelli Stefano De Servi Ospedale di Legnano Legnano - MI (Italy) Paolo Della Bella Marcelo Fernando Di Carli Brigham and Women s Hospital Boston (MA, USA) Perry Elliott The Heart Hospital London (United Kingdom) Maria Frigerio Ospedale Niguarda Ca Granda Guido Grassi Università degli Studi di Milano Bicocca Anders Hamsten Karolinska Institute Stockholm (Sweden) Johannes Holzmeister University Hospital Zurich (Switzerland) Juhani Knuuti Turku University Hospital and University of Turku Turku (Finland) Giovanni La Canna Stéphane Laurent Hopital Européen George Pompidou Paris (France) Peter Libby Brigham and Women s Hospital Boston (MA, USA) Joao Lima The Johns Hopkins University School of Medicine Baltimore (MD, USA) Thomas F. Lüscher University Hospital Zurich (Switzerland) Aldo Pietro Maggioni Centro Studi A.N.M.C.O. Florence (Italy) Alberto Margonato Mario Marzilli Università degli Studi di Pisa Pisa (Italy) Neil Moat The Royal Brompton Hospital London (United Kingdom) 18 19

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 20 Lucilla Monti Danilo Neglia Fondazione Toscana Gabriele Monasterio Pisa (Italy) Iacopo Olivotto Azienda Ospedaliero-Universitaria Careggi Florence (Italy) Mauro Pepi Centro Cardiologico Monzino Marc Pfeffer Brigham and Women s Hospital Boston (MA, USA) Sven Plein University of Leeds Leeds (United Kingdom) Sanjay K. Prasad Imperial College London London (United Kingdom) Paul M. Ridker Brigham and Women s Hospital Boston (MA, USA) Ornella E. Rimoldi Aldo Rinaldi King s College London London (United Kingdom) Heinz-Peter Schultheiss Charité-Campus Benjamin Franklin Berlin (Germany) Hiroaki Shimokawa Tohoku University Graduate School of Medicine Tohoku (Japan) Maarten L. Simoons Erasmus University Rotterdam Rotterdam (The Netherlands) Gaetano Thiene Università degli Studi di Padova Padua (Italy) Bruno Trimarco Università degli Studi di Napoli Federico II Naples (Italy) Alec Vahanian Bichat University Hospital Paris (France) Renu Virmani Path Institute Gaithersburg (MD, USA) Massimo Volpe Sapienza - Università di Roma Ospedale Sant Andrea Rome (Italy) David A. Wood Imperial College London London (United Kingdom) Alberto Roghi Ospedale Niguarda Ca Granda 20 21

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 22 MILAN CARDIOLOGY, February, 13 th -15 th, 2014 Physician Postgraduate Please complete and return the entire registration form to: San Raffaele Congress Centre Via Olgettina, 58-20132 Milan - Italy e-mail: info@milancardiology2014.com Fax: +39 02 2643 3754 Surname Institute Mailing address Name City Country Postal Code Phone e-mail Fax Date Signature ACCORDING TO ITALIAN LAW N. 196/2003 ON PRIVACY PROTECTION, ALL PERSONAL DATA WILL BE TREATED STRICTLY CONFIDENTIALLY. AT ANY TIME YOU CAN ASK SAN RAFFAELE CONGRESS CENTRE TO MODIFY OR CANCEL YOUR DATA.

02-2014 Prog CARDIOLOGY:02-2014 Prog CARDIOLOGY.qxp 07/01/14 10:55 Pagina 24