Nutritional Assessment of Patients with Respiratory Disease C H A P T E R 1 7

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Nutritional Assessment of Patients with Respiratory Disease C H A P T E R 1 7

Nutritional Status Major factor influencing acute and long term outcomes Quantity and quality of food affects the efficiency of the metabolic process Nutrients can enhance or harm immune functions Important to understand the interdependence of nutrition and respiratory care

Integration of Organ Systems

Components of the Respiratory System Neurologic Drives and controls ventilation Requires glucose, protein Respiratory Muscles Pump that drives the lungs Energy from glucose, fatty acids, muscle glycogen Cardiovascular Carries both nutrients and oxygen to the tissues Protein, carbohydrates, fat, water, vitamins Gas Exchange V/Q matching Surfactant synthesis, humidity and mucociliary performance

Metabolism Produces body heat Requires fuel = food Combustion requires oxygen to produce ATP Catabolism Anabolism 4 major phases Digestion Production of acetyl CoA Krebs/citric acid cycle ATP production

Metabolism Metabolic rates of the tissues dictate the amount of oxygen needing to be picked up in the lungs BMR/BEE REE Sufficient food maintains an equilibrium energy production and demands of environment Too little food ingested use of stored energy Too much food ingested convert and store as fat Too much or too little cause the functional capability to decrease

Energy Use Determined by: Direct calorimetry Indirect calorimetry Respiratory measurements

Metabolic Cart Bedside monitors O 2 CO 2 analyzers; flow transducers Nose clips/mouthpiece Hood/Tent Through the ventilator circuit Procedure: Collect expired gas Analyze for carbon dioxide and oxygen Measure the volume of gas collected Calculate VCO 2 and VO 2 and convert to kilocalories Weir Equation Determines energy expenditure

Monitoring incorporated into existing Hardware In order to provide an accurate breath-bybreath measurement of respiratory gas exchange the module must algorithmically integrate side stream gas concentrations (CO2 and O2) as well as the flows and volumes generated by each breath. This is done with the D-Lite + flow sensor in conjunction with the fast paramagnetic oxygen sensor and the infrared gas bench for CO2 measurement. Thus, the measurement can be thought of as a three stage technique whereby flows and concentrations are synchronized and gas volumes calculated.

Variations in oxygen consumption and carbon dioxide production (expressed as percent change) associated with diagnostic and therapeutic interactions in an ICU patient.

Clinical Usefulness of Metabolic Monitoring Determines the REE Guides appropriate nutritional support Tailor support to meet the patient s needs Continued evaluation of adequacy and appropriateness of nutritional support Provides relationship between DO 2 (oxygen delivery) and VO 2 (oxygen consumption) Guide for ventilator mode and setting selection, assess weaning strategies; predictor of patient outcomes

Limitations No contraindications other than caution when assembling equipment (brief interruption of mechanical ventilation while connecting measurement lines hypoxemia, bradycardia) Leaks in the system prevent accurate measurements\ Patient condition or activities may prevent measurements from occuring Costly equipment with few comprehensive studies demonstrating improved outcomes, decreased ventilator times, or shorter ICU/hospital stays

Routes of Nutritional Administration Enteral Preferred route Sites Nasogastric, nasoduodenal nasojejunal Gastrostomy Jejunostomy Esophagotomy PEG/PEJ Given by bolus, intermittent, or continuous drip Risk of Aspiration Parenteral Use peripheral or central vein TPN Risk of infection

Nutritional Depletion Blood sugar levels; gluconeogenesis Protein depletion Decrease in respiratory muscle strength Weight loss Malnutrition PEM

Nutritional Repletion Hindered in Respiratory patients Respiratory response is usually regulated by VCO 2 Critical care patients require continuous assistance with nutrition and breathing

Respiratory Quotient Metabolic pathways use O2 produce CO2 RQ = ratio of VCO2 to VO2 Determined by the amount of fat, carbohydrate, or protein eaten PROTEIN RQ = 0.85 FAT RQ = 0.7 CARB RQ = 1.0 Mixture = 0.8 Minimum nutrient levels to avoid deficiency symptoms and low enough to prevent toxicity

Nutritional Elements Carbohydrate Largest amount of intake Complex vs simple Evaluate response CO2 load and production Protein 12-15% intake Quantity and quality Extremes are detrimental Nitrogen balance Fat Best storage form for energy Efficient way to provide calories Quality saturated, polyunsaturated, monounsaturated Vitamin, Mineral, Other Variety of foods Supplementation Fluids, Electrolytes Monitor intake/output

The role of the RT in nutrition NOT responsible for the nutritional assessment Familiar with the process and contribute to the data gathering History Physical exam Clinical lab values

Respiratory Assessment Inspection BMI Cachectic Kwashiorkor/Marasmus Obesity Muscle condition JVP, acites, edema fluid balance Sputum viscosity Auscultation Course or fine crackles Wheezing Laboratory Findings PFT measurements PEP, PIP Lung compliance ABG values